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Items: 15


Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry.

Xu X, Huang Y, Pan H, Molden R, Qiu H, Daly TJ, Li N.

PLoS One. 2019 Oct 16;14(10):e0223899. doi: 10.1371/journal.pone.0223899. eCollection 2019.


Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis.

Bhanu NV, Sidoli S, Yuan ZF, Molden RC, Garcia BA.

J Biol Chem. 2019 May 17;294(20):8296-8308. doi: 10.1074/jbc.RA118.004977. Epub 2019 Mar 14.


Preliminary Study of Testosterone and Empathy in Determining Recidivism and Antisocial Behavior.

House SJ, Laan JM, Molden RK, Ritchie JC, Stowe ZN.

J Forensic Sci. 2017 Sep;62(5):1360-1365. doi: 10.1111/1556-4029.13469. Epub 2017 Feb 15.


A core viral protein binds host nucleosomes to sequester immune danger signals.

Avgousti DC, Herrmann C, Kulej K, Pancholi NJ, Sekulic N, Petrescu J, Molden RC, Blumenthal D, Paris AJ, Reyes ED, Ostapchuk P, Hearing P, Seeholzer SH, Worthen GS, Black BE, Garcia BA, Weitzman MD.

Nature. 2016 Jul 7;535(7610):173-7. Epub 2016 Jun 29.


Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.

Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW.

Science. 2016 May 13;352(6287):844-9. doi: 10.1126/science.aac7272.


Monitoring Cellular Phosphorylation Signaling Pathways into Chromatin and Down to the Gene Level.

Han Y, Yuan ZF, Molden RC, Garcia BA.

Mol Cell Proteomics. 2016 Mar;15(3):834-53. doi: 10.1074/mcp.M115.053421. Epub 2015 Nov 5.


Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications.

Molden RC, Bhanu NV, LeRoy G, Arnaudo AM, Garcia BA.

Epigenetics Chromatin. 2015 Apr 22;8:15. doi: 10.1186/s13072-015-0006-8. eCollection 2015.


EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra.

Yuan ZF, Lin S, Molden RC, Cao XJ, Bhanu NV, Wang X, Sidoli S, Liu S, Garcia BA.

Mol Cell Proteomics. 2015 Jun;14(6):1696-707. doi: 10.1074/mcp.M114.046011. Epub 2015 Mar 24.


Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis.

Sidoli S, Yuan ZF, Lin S, Karch K, Wang X, Bhanu N, Arnaudo AM, Britton LM, Cao XJ, Gonzales-Cope M, Han Y, Liu S, Molden RC, Wein S, Afjehi-Sadat L, Garcia BA.

Proteomics. 2015 May;15(9):1459-69. doi: 10.1002/pmic.201400483.


Evaluation of proteomic search engines for the analysis of histone modifications.

Yuan ZF, Lin S, Molden RC, Garcia BA.

J Proteome Res. 2014 Oct 3;13(10):4470-8. doi: 10.1021/pr5008015. Epub 2014 Sep 7.


Middle-Down and Top-Down Mass Spectrometric Analysis of Co-occurring Histone Modifications.

Molden RC, Garcia BA.

Curr Protoc Protein Sci. 2014 Aug 1;77:23.7.1-28. doi: 10.1002/0471140864.ps2307s77. Review.


Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination.

Molden RC, Goya J, Khan Z, Garcia BA.

Mol Cell Proteomics. 2014 Apr;13(4):1106-18. doi: 10.1074/mcp.O113.036145. Epub 2014 Feb 16.


Neutron-encoded mass signatures for quantitative top-down proteomics.

Rhoads TW, Rose CM, Bailey DJ, Riley NM, Molden RC, Nestler AJ, Merrill AE, Smith LM, Hebert AS, Westphall MS, Pagliarini DJ, Garcia BA, Coon JJ.

Anal Chem. 2014 Mar 4;86(5):2314-9. doi: 10.1021/ac403579s. Epub 2014 Feb 19.


RNA catalysis through compartmentalization.

Strulson CA, Molden RC, Keating CD, Bevilacqua PC.

Nat Chem. 2012 Nov;4(11):941-6. doi: 10.1038/nchem.1466. Epub 2012 Oct 14.


Revealing histone variant induced changes via quantitative proteomics.

Arnaudo AM, Molden RC, Garcia BA.

Crit Rev Biochem Mol Biol. 2011 Aug;46(4):284-94. doi: 10.3109/10409238.2011.577052. Review.

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