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Items: 28


Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats.

Wong VKW, Qiu C, Xu SW, Law BYK, Zeng W, Wang H, Michelangeli F, Dias IRSR, Qu YQ, Chan TW, Han Y, Zhang N, Mok SWF, Chen X, Yu L, Pan H, Hamdoun S, Efferth T, Yu WJ, Zhang W, Li Z, Xie Y, Luo R, Jiang Q, Liu L.

Br J Pharmacol. 2019 May 23. doi: 10.1111/bph.14718. [Epub ahead of print]


Novel dauricine derivatives suppress cancer via autophagy-dependent cell death.

Zhou X, Qu YQ, Zheng Z, Law BYK, Mok SWF, Jiang ZH, Wong VKW, Bai LP.

Bioorg Chem. 2019 Mar;83:450-460. doi: 10.1016/j.bioorg.2018.10.074. Epub 2018 Nov 2.


Intra-Articular Delivery of Quercetin Using Thermosensitive Hydrogel Attenuate Cartilage Degradation in an Osteoarthritis Rat Model.

Mok SW, Fu SC, Cheuk YC, Chu IM, Chan KM, Qin L, Yung SH, Kevin Ho KW.

Cartilage. 2018 Aug 30:1947603518796550. doi: 10.1177/1947603518796550. [Epub ahead of print]


A Method for Rapid Screening of Anilide-Containing AMPK Modulators Based on Computational Docking and Biological Validation.

Mok SWF, Zeng W, Niu Y, Coghi P, Wu Y, Sin WM, Ng SI, Gordillo-Martínez F, Gao JY, Law BYK, Liu L, Yao X, Wong VKW.

Front Pharmacol. 2018 Jul 3;9:710. doi: 10.3389/fphar.2018.00710. eCollection 2018.


Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy.

Yang GJ, Wang W, Mok SWF, Wu C, Law BYK, Miao XM, Wu KJ, Zhong HJ, Wong CY, Wong VKW, Ma DL, Leung CH.

Angew Chem Int Ed Engl. 2018 Oct 1;57(40):13091-13095. doi: 10.1002/anie.201807305. Epub 2018 Jul 19.


2-Aminoethoxydiphenylborane sensitizes anti-tumor effect of bortezomib via suppression of calcium-mediated autophagy.

Qu YQ, Gordillo-Martinez F, Law BYK, Han Y, Wu A, Zeng W, Lam WK, Ho C, Mok SWF, He HQ, Wong VKW, Wang R.

Cell Death Dis. 2018 Mar 2;9(3):361. doi: 10.1038/s41419-018-0397-0.


The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity.

de Seabra Rodrigues Dias IR, Mok SWF, Gordillo-Martínez F, Khan I, Hsiao WWL, Law BYK, Wong VKW, Liu L.

Front Pharmacol. 2018 Jan 8;8:962. doi: 10.3389/fphar.2017.00962. eCollection 2017.


New perspectives of cobalt tris(bipyridine) system: anti-cancer effect and its collateral sensitivity towards multidrug-resistant (MDR) cancers.

Law BYK, Qu YQ, Mok SWF, Liu H, Zeng W, Han Y, Gordillo-Martinez F, Chan WK, Wong KM, Wong VKW.

Oncotarget. 2017 Jul 5;8(33):55003-55021. doi: 10.18632/oncotarget.18991. eCollection 2017 Aug 15.


Pathogenesis of thromboangiitis obliterans: Gene polymorphism and immunoregulation of human vascular endothelial cells.

Sun XL, Law BY, de Seabra Rodrigues Dias IR, Mok SWF, He YZ, Wong VK.

Atherosclerosis. 2017 Oct;265:258-265. doi: 10.1016/j.atherosclerosis.2017.08.009. Epub 2017 Aug 18. Review.


N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization.

Law BYK, Mok SWF, Chen J, Michelangeli F, Jiang ZH, Han Y, Qu YQ, Qiu ACL, Xu SW, Xue WW, Yao XJ, Gao JY, Javed MU, Coghi P, Liu L, Wong VKW.

Front Pharmacol. 2017 Jun 16;8:388. doi: 10.3389/fphar.2017.00388. eCollection 2017.


Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells.

Kadioglu O, Law BYK, Mok SWF, Xu SW, Efferth T, Wong VKW.

Front Pharmacol. 2017 May 5;8:238. doi: 10.3389/fphar.2017.00238. eCollection 2017.


Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death.

Law BYK, Gordillo-Martínez F, Qu YQ, Zhang N, Xu SW, Coghi PS, Mok SWF, Guo J, Zhang W, Leung ELH, Fan XX, Wu AG, Chan WK, Yao XJ, Wang JR, Liu L, Wong VKW.

Oncotarget. 2017 May 2;8(18):30077-30091. doi: 10.18632/oncotarget.15616.


An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB.

Kang TS, Wang W, Zhong HJ, Dong ZZ, Huang Q, Mok SW, Leung CH, Wong VK, Ma DL.

Cancer Lett. 2017 Jun 28;396:76-84. doi: 10.1016/j.canlet.2017.03.016. Epub 2017 Mar 18.


Intra-articular injection of an antioxidant formulation did not improve structural degeneration in a rat model of post-traumatic osteoarthritis.

Cheuk YC, Fu SC, Mok SW, Ho KK, Hung LK, Chan KM.

J Orthop Translat. 2016 Sep 8;8:25-31. doi: 10.1016/ eCollection 2017 Jan.


Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol.

Xu SW, Law BY, Mok SW, Leung EL, Fan XX, Coghi PS, Zeng W, Leung CH, Ma DL, Liu L, Wong VK.

Int J Oncol. 2016 Oct;49(4):1576-88. doi: 10.3892/ijo.2016.3644. Epub 2016 Aug 3.


From the printer: Potential of three-dimensional printing for orthopaedic applications.

Mok SW, Nizak R, Fu SC, Ho KK, Qin L, Saris DBF, Chan KM, Malda J.

J Orthop Translat. 2016 May 10;6:42-49. doi: 10.1016/ eCollection 2016 Jul. Review.


New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy.

Law BY, Mok SW, Wu AG, Lam CW, Yu MX, Wong VK.

Molecules. 2016 Mar 17;21(3):359. doi: 10.3390/molecules21030359. Review.


Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers.

Law BY, Mok SW, Chan WK, Xu SW, Wu AG, Yao XJ, Wang JR, Liu L, Wong VK.

Oncotarget. 2016 Feb 16;7(7):8090-104. doi: 10.18632/oncotarget.6980.


The FHL2 regulation in the transcriptional circuitry of human cancers.

Cao CY, Mok SW, Cheng VW, Tsui SK.

Gene. 2015 Nov 1;572(1):1-7. doi: 10.1016/j.gene.2015.07.043. Epub 2015 Jul 26. Review.


Second harmonic correlation spectroscopy: a method for determining surface binding kinetics and thermodynamics.

Sly KL, Mok SW, Conboy JC.

Anal Chem. 2013 Sep 3;85(17):8429-35. doi: 10.1021/ac4018742. Epub 2013 Aug 22.


B cell-specific S1PR1 deficiency blocks prion dissemination between secondary lymphoid organs.

Mok SW, Proia RL, Brinkmann V, Mabbott NA.

J Immunol. 2012 May 15;188(10):5032-40. doi: 10.4049/jimmunol.1200349. Epub 2012 Apr 13.


Assembly of lipid bilayers on silica and modified silica colloids by reconstitution of dried lipid films.

Ross EE, Mok SW, Bugni SR.

Langmuir. 2011 Jul 19;27(14):8634-44. doi: 10.1021/la200952c. Epub 2011 Jun 15.


Accelerated prion replication in, but prolonged survival times of, prion-infected CXCR3-/- mice.

Riemer C, Schultz J, Burwinkel M, Schwarz A, Mok SW, Gültner S, Bamme T, Norley S, van Landeghem F, Lu B, Gerard C, Baier M.

J Virol. 2008 Dec;82(24):12464-71. doi: 10.1128/JVI.01371-08. Epub 2008 Oct 8.


Evaluation of drugs for treatment of prion infections of the central nervous system.

Riemer C, Burwinkel M, Schwarz A, Gültner S, Mok SW, Heise I, Holtkamp N, Baier M.

J Gen Virol. 2008 Feb;89(Pt 2):594-7. doi: 10.1099/vir.0.83281-0.


Role of galectin-3 in prion infections of the CNS.

Mok SW, Riemer C, Madela K, Hsu DK, Liu FT, Gültner S, Heise I, Baier M.

Biochem Biophys Res Commun. 2007 Aug 3;359(3):672-8. Epub 2007 Jun 4.


Simvastatin prolongs survival times in prion infections of the central nervous system.

Mok SW, Thelen KM, Riemer C, Bamme T, Gültner S, Lütjohann D, Baier M.

Biochem Biophys Res Commun. 2006 Sep 22;348(2):697-702. Epub 2006 Jul 31.


3-Methyl-4-chlorophenol for prion decontamination of medical devices.

Riemer C, Bamme T, Mok SW, Baier M.

Infect Control Hosp Epidemiol. 2006 Jul;27(7):778-80. Epub 2006 Jun 19.


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