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Items: 23

1.

Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation.

Moi D, Nocentini A, Deplano A, Balboni G, Supuran CT, Onnis V.

Eur J Med Chem. 2019 Aug 22;182:111638. doi: 10.1016/j.ejmech.2019.111638. [Epub ahead of print]

PMID:
31472471
2.

Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors.

Moi D, Foster PA, Rimmer LG, Jaffri A, Deplano A, Balboni G, Onnis V, Potter BVL.

Eur J Med Chem. 2019 Aug 12;182:111614. doi: 10.1016/j.ejmech.2019.111614. [Epub ahead of print]

PMID:
31422224
3.

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.

Géraldy M, Morgen M, Sehr P, Steimbach RR, Moi D, Ridinger J, Oehme I, Witt O, Malz M, Nogueira MS, Koch O, Gunkel N, Miller AK.

J Med Chem. 2019 May 9;62(9):4426-4443. doi: 10.1021/acs.jmedchem.8b01936. Epub 2019 Apr 29.

PMID:
30964290
4.

Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones.

Demurtas M, Baldisserotto A, Lampronti I, Moi D, Balboni G, Pacifico S, Vertuani S, Manfredini S, Onnis V.

Bioorg Chem. 2019 Apr;85:568-576. doi: 10.1016/j.bioorg.2019.02.007. Epub 2019 Feb 10.

PMID:
30825715
5.

Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity.

Baldisserotto A, Demurtas M, Lampronti I, Moi D, Balboni G, Vertuani S, Manfredini S, Onnis V.

Eur J Med Chem. 2018 Aug 5;156:118-125. doi: 10.1016/j.ejmech.2018.07.001. Epub 2018 Jul 2.

PMID:
30006157
6.

Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.

Wagner F, Holzapfel BM, McGovern JA, Shafiee A, Baldwin JG, Martine LC, Lahr CA, Wunner FM, Friis T, Bas O, Boxberg M, Prodinger PM, Shokoohmand A, Moi D, Mazzieri R, Loessner D, Hutmacher DW.

Biomaterials. 2018 Jul;171:230-246. doi: 10.1016/j.biomaterials.2018.04.030. Epub 2018 Apr 16.

PMID:
29705656
7.

Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study.

Shafiee A, McGovern JA, Lahr CA, Meinert C, Moi D, Wagner F, Landgraf M, De-Juan-Pardo E, Mazzieri R, Hutmacher DW.

Int J Cancer. 2018 Sep 15;143(6):1470-1482. doi: 10.1002/ijc.31528. Epub 2018 May 7.

8.

Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy.

Nocentini A, Moi D, Balboni G, Salvadori S, Onnis V, Supuran CT.

Bioorg Chem. 2018 Apr;77:633-639. doi: 10.1016/j.bioorg.2018.02.021. Epub 2018 Feb 23.

PMID:
29502024
9.

Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy.

Zeng B, Middelberg AP, Gemiarto A, MacDonald K, Baxter AG, Talekar M, Moi D, Tullett KM, Caminschi I, Lahoud MH, Mazzieri R, Dolcetti R, Thomas R.

J Clin Invest. 2018 May 1;128(5):1971-1984. doi: 10.1172/JCI96791. Epub 2018 Apr 9.

10.

Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors.

Nocentini A, Moi D, Balboni G, Onnis V, Supuran CT.

Bioorg Chem. 2018 Apr;77:293-299. doi: 10.1016/j.bioorg.2018.01.023. Epub 2018 Jan 31.

PMID:
29421705
11.

B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity.

McKee SJ, Tuong ZK, Kobayashi T, Doff BL, Soon MS, Nissen M, Lam PY, Keane C, Vari F, Moi D, Mazzieri R, Leggatt G, Gandhi MK, Mattarollo SR.

Oncoimmunology. 2017 Dec 18;7(2):e1393599. doi: 10.1080/2162402X.2017.1393599. eCollection 2018.

12.

Interleukin-23 regulates interleukin-17 expression in wounds, and its inhibition accelerates diabetic wound healing through the alteration of macrophage polarization.

Lee J, Rodero MP, Patel J, Moi D, Mazzieri R, Khosrotehrani K.

FASEB J. 2018 Apr;32(4):2086-2094. doi: 10.1096/fj.201700773R. Epub 2018 Jan 5.

PMID:
29208701
13.

Engineering a humanized bone organ model in mice to study bone metastases.

Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, Wunner FM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D, Oussenko T, Piccinini E, Zandstra PW, Mazzieri R, Lévesque JP, Dalton PD, Taubenberger AV, Hutmacher DW.

Nat Protoc. 2017 Apr;12(4):639-663. doi: 10.1038/nprot.2017.002. Epub 2017 Mar 2.

PMID:
28253234
14.

Arabidopsis HAP2/GCS1 is a gamete fusion protein homologous to somatic and viral fusogens.

Valansi C, Moi D, Leikina E, Matveev E, Graña M, Chernomordik LV, Romero H, Aguilar PS, Podbilewicz B.

J Cell Biol. 2017 Mar 6;216(3):571-581. doi: 10.1083/jcb.201610093. Epub 2017 Jan 30.

15.

Angiopoietin 2 expression in the cornea and its control of corneal neovascularisation.

Ferrari G, Giacomini C, Bignami F, Moi D, Ranghetti A, Doglioni C, Naldini L, Rama P, Mazzieri R.

Br J Ophthalmol. 2016 Jul;100(7):1005-1010. doi: 10.1136/bjophthalmol-2015-307901. Epub 2016 May 4.

PMID:
27146154
16.

Urokinase Receptor Promotes Skin Tumor Formation by Preventing Epithelial Cell Activation of Notch1.

Mazzieri R, Pietrogrande G, Gerasi L, Gandelli A, Colombo P, Moi D, Brombin C, Ambrosi A, Danese S, Mignatti P, Blasi F, D'Alessio S.

Cancer Res. 2015 Nov 15;75(22):4895-909. doi: 10.1158/0008-5472.CAN-15-0378. Epub 2015 Nov 2.

17.

Targeted genome editing in human repopulating haematopoietic stem cells.

Genovese P, Schiroli G, Escobar G, Tomaso TD, Firrito C, Calabria A, Moi D, Mazzieri R, Bonini C, Holmes MC, Gregory PD, van der Burg M, Gentner B, Montini E, Lombardo A, Naldini L.

Nature. 2014 Jun 12;510(7504):235-240. doi: 10.1038/nature13420. Epub 2014 May 28.

18.

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression.

Escobar G, Moi D, Ranghetti A, Ozkal-Baydin P, Squadrito ML, Kajaste-Rudnitski A, Bondanza A, Gentner B, De Palma M, Mazzieri R, Naldini L.

Sci Transl Med. 2014 Jan 1;6(217):217ra3. doi: 10.1126/scitranslmed.3006353.

19.

miR-511-3p modulates genetic programs of tumor-associated macrophages.

Squadrito ML, Pucci F, Magri L, Moi D, Gilfillan GD, Ranghetti A, Casazza A, Mazzone M, Lyle R, Naldini L, De Palma M.

Cell Rep. 2012 Feb 23;1(2):141-54. doi: 10.1016/j.celrep.2011.12.005. Epub 2012 Feb 9.

20.

Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.

Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, Berti A, Politi LS, Gentner B, Brown JL, Naldini L, De Palma M.

Cancer Cell. 2011 Apr 12;19(4):512-26. doi: 10.1016/j.ccr.2011.02.005.

21.

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships.

Pucci F, Venneri MA, Biziato D, Nonis A, Moi D, Sica A, Di Serio C, Naldini L, De Palma M.

Blood. 2009 Jul 23;114(4):901-14. doi: 10.1182/blood-2009-01-200931. Epub 2009 Apr 21.

22.

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.

De Palma M, Mazzieri R, Politi LS, Pucci F, Zonari E, Sitia G, Mazzoleni S, Moi D, Venneri MA, Indraccolo S, Falini A, Guidotti LG, Galli R, Naldini L.

Cancer Cell. 2008 Oct 7;14(4):299-311. doi: 10.1016/j.ccr.2008.09.004.

23.

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