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Title: Once-weekly Oral Dosing of MK-8591 Protects Male Rhesus Macaques from Intrarectal SHIV109CP3 Challenge.

Markowitz M, Gettie A, St Bernard L, Andrews CD, Mohri H, Horowitz A, Grasperge BF, Blanchard JL, Niu T, Sun L, Fillgrove K, Hazuda DJ, Grobler JA.

J Infect Dis. 2019 Jun 7. pii: jiz271. doi: 10.1093/infdis/jiz271. [Epub ahead of print]


Poly-ICLC, a TLR3 Agonist, Induces Transient Innate Immune Responses in Patients With Treated HIV-Infection: A Randomized Double-Blinded Placebo Controlled Trial.

Saxena M, Sabado RL, La Mar M, Mohri H, Salazar AM, Dong H, Correa Da Rosa J, Markowitz M, Bhardwaj N, Miller E.

Front Immunol. 2019 Apr 9;10:725. doi: 10.3389/fimmu.2019.00725. eCollection 2019.


Male reproductive health statement (XIIIth international symposium on Spermatology, may 9th-12th 2018, Stockholm, Sweden.

Levine H, Mohri H, Ekbom A, Ramos L, Parker G, Roldan E, Jovine L, Koelle S, Lindstrand A, Immler S, Mortimer S, Mortimer D, van der Horst G, Ishijima S, Aneck-Hahn N, Baldi E, Menkveld R, Rothmann SA, Giwercman A, Giwercman Y, Holmberg M, Kvist U, Björndahl L, Holmberg R, Arver S, Flanagan J, Drevet JR.

Basic Clin Androl. 2018 Oct 29;28:13. doi: 10.1186/s12610-018-0077-z. eCollection 2018.


MTMR4, a phosphoinositide-specific 3'-phosphatase, regulates TFEB activity and the endocytic and autophagic pathways.

Pham HQ, Yoshioka K, Mohri H, Nakata H, Aki S, Ishimaru K, Takuwa N, Takuwa Y.

Genes Cells. 2018 Jul 2. doi: 10.1111/gtc.12609. [Epub ahead of print]


Hearing vulnerability after noise exposure in a mouse model of reactive oxygen species overproduction.

Morioka S, Sakaguchi H, Yamaguchi T, Ninoyu Y, Mohri H, Nakamura T, Hisa Y, Ogita K, Saito N, Ueyama T.

J Neurochem. 2018 Aug;146(4):459-473. doi: 10.1111/jnc.14451. Epub 2018 Jul 23.


Roles of Cdc42 and Rac in Bergmann glia during cerebellar corticogenesis.

Sakamoto I, Ueyama T, Hayashibe M, Nakamura T, Mohri H, Kiyonari H, Shigyo M, Tohda C, Saito N.

Exp Neurol. 2018 Apr;302:57-67. doi: 10.1016/j.expneurol.2017.12.003. Epub 2017 Dec 15.


Newly Acquired Infection With Multidrug-Resistant HIV-1 in a Patient Adherent to Preexposure Prophylaxis.

Markowitz M, Grossman H, Anderson PL, Grant R, Gandhi M, Horng H, Mohri H.

J Acquir Immune Defic Syndr. 2017 Dec 1;76(4):e104-e106. doi: 10.1097/QAI.0000000000001534. No abstract available.


Impact of matrix stiffness on fibroblast function.

El-Mohri H, Wu Y, Mohanty S, Ghosh G.

Mater Sci Eng C Mater Biol Appl. 2017 May 1;74:146-151. doi: 10.1016/j.msec.2017.02.001. Epub 2017 Feb 7.


Cabotegravir long acting injection protects macaques against intravenous challenge with SIVmac251.

Andrews CD, Bernard LS, Poon AY, Mohri H, Gettie N, Spreen WR, Gettie A, Russell-Lodrigue K, Blanchard J, Hong Z, Ho DD, Markowitz M.

AIDS. 2017 Feb 20;31(4):461-467. doi: 10.1097/QAD.0000000000001343.


Clinical impact of targeted amplicon sequencing for meningioma as a practical clinical-sequencing system.

Yuzawa S, Nishihara H, Yamaguchi S, Mohri H, Wang L, Kimura T, Tsuda M, Tanino M, Kobayashi H, Terasaka S, Houkin K, Sato N, Tanaka S.

Mod Pathol. 2016 Jul;29(7):708-16. doi: 10.1038/modpathol.2016.81. Epub 2016 Apr 22.


Viral envelope is a major determinant of enhanced fitness of a multidrug-resistant HIV-1 variant.

Mohri H, Prada N, Markowitz M.

J Acquir Immune Defic Syndr. 2015 Apr 15;68(5):487-94. doi: 10.1097/QAI.0000000000000524.


A long-acting integrase inhibitor protects female macaques from repeated high-dose intravaginal SHIV challenge.

Andrews CD, Yueh YL, Spreen WR, St Bernard L, Boente-Carrera M, Rodriguez K, Gettie A, Russell-Lodrigue K, Blanchard J, Ford S, Mohri H, Cheng-Mayer C, Hong Z, Ho DD, Markowitz M.

Sci Transl Med. 2015 Jan 14;7(270):270ra4. doi: 10.1126/scitranslmed.3010298.


GSK1265744 demonstrates robust in vitro activity against various clades of HIV-1.

Karmon SL, Mohri H, Spreen W, Markowitz M.

J Acquir Immune Defic Syndr. 2015 Mar 1;68(3):e39-41. doi: 10.1097/QAI.0000000000000469. No abstract available.


Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus.

Andrews CD, Spreen WR, Mohri H, Moss L, Ford S, Gettie A, Russell-Lodrigue K, Bohm RP, Cheng-Mayer C, Hong Z, Markowitz M, Ho DD.

Science. 2014 Mar 7;343(6175):1151-4. doi: 10.1126/science.1248707. Epub 2014 Mar 4.


A randomized open-label study of 3- versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individuals.

Markowitz M, Evering TH, Garmon D, Caskey M, La Mar M, Rodriguez K, Sahi V, Palmer S, Prada N, Mohri H.

J Acquir Immune Defic Syndr. 2014 Jun 1;66(2):140-7. doi: 10.1097/QAI.0000000000000111.


Immunohistochemical evaluation of O6 -methylguanine DNA methyltransferase (MGMT) expression in 117 cases of glioblastoma.

Miyazaki M, Nishihara H, Terasaka S, Kobayashi H, Yamaguchi S, Ito T, Kamoshima Y, Fujimoto S, Kaneko S, Katoh M, Ishii N, Mohri H, Tanino M, Kimura T, Tanaka S.

Neuropathology. 2014 Jun;34(3):268-76. doi: 10.1111/neup.12091. Epub 2014 Jan 7.


Pax1 acts as a negative regulator of chondrocyte maturation.

Takimoto A, Mohri H, Kokubu C, Hiraki Y, Shukunami C.

Exp Cell Res. 2013 Dec 10;319(20):3128-39. doi: 10.1016/j.yexcr.2013.09.015. Epub 2013 Sep 27.


Clinicopathological evaluation of cyclooxygenase-2 expression in meningioma: immunohistochemical analysis of 76 cases of low and high-grade meningioma.

Kato Y, Nishihara H, Mohri H, Kanno H, Kobayashi H, Kimura T, Tanino M, Terasaka S, Tanaka S.

Brain Tumor Pathol. 2014 Jan;31(1):23-30. doi: 10.1007/s10014-012-0127-8. Epub 2012 Dec 19. Erratum in: Brain Tumor Pathol. 2014 Jan;31(1):31.


Immunohistochemical molecular gene expression profile of metastatic brain tumor as a potent personalized medicine.

Kato Y, Nishihara H, Yuzawa S, Mohri H, Kanno H, Hatanaka Y, Kimura T, Tanino M, Tanaka S.

Brain Tumor Pathol. 2013 Jul;30(3):167-74. doi: 10.1007/s10014-012-0124-y. Epub 2012 Nov 20. Erratum in: Brain Tumor Pathol. 2013 Oct;30(4):266-7.


Tubulin-dynein system in flagellar and ciliary movement.

Mohri H, Inaba K, Ishijima S, Baba SA.

Proc Jpn Acad Ser B Phys Biol Sci. 2012;88(8):397-415. Review.


Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antiviral therapy initiated during primary infection.

Evering TH, Mehandru S, Racz P, Tenner-Racz K, Poles MA, Figueroa A, Mohri H, Markowitz M.

PLoS Pathog. 2012 Feb;8(2):e1002506. doi: 10.1371/journal.ppat.1002506. Epub 2012 Feb 2.


RAGE mediates vascular injury and inflammation after global cerebral ischemia.

Kamide T, Kitao Y, Takeichi T, Okada A, Mohri H, Schmidt AM, Kawano T, Munesue S, Yamamoto Y, Yamamoto H, Hamada J, Hori O.

Neurochem Int. 2012 Feb;60(3):220-8. doi: 10.1016/j.neuint.2011.12.008. Epub 2011 Dec 19.


Identification of the starting point for spermatogenesis resumption in the post-diapause development of the sweet potato hornworm, Agrius convolvuli L.

Kubo-Irie M, Yamaguchi T, Tanaka Y, Yamazaki I, Irie M, Mohri H, Shimoda M.

J Insect Physiol. 2011 Jun;57(6):784-90. doi: 10.1016/j.jinsphys.2011.03.006. Epub 2011 Mar 21.


Phylogeny, biogeography, and host-plant association in the subfamily Apaturinae (Insecta: Lepidoptera: Nymphalidae) inferred from eight nuclear and seven mitochondrial genes.

Ohshima I, Tanikawa-Dodo Y, Saigusa T, Nishiyama T, Kitani M, Hasebe M, Mohri H.

Mol Phylogenet Evol. 2010 Dec;57(3):1026-36. doi: 10.1016/j.ympev.2010.09.018. Epub 2010 Nov 4.


The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection.

Markowitz M, Vaida F, Hare CB, Boden D, Mohri H, Hecht FM, Kalayjian RC, Conrad A, Mildvan D, Aberg J, Hogan C, Kilby JM, Balfour HH Jr, Schafer K, Richman D, Little S.

J Infect Dis. 2010 May 1;201(9):1298-302. doi: 10.1086/651664.


Natural polymorphisms of human immunodeficiency virus type 1 integrase and inherent susceptibilities to a panel of integrase inhibitors.

Low A, Prada N, Topper M, Vaida F, Castor D, Mohri H, Hazuda D, Muesing M, Markowitz M.

Antimicrob Agents Chemother. 2009 Oct;53(10):4275-82. doi: 10.1128/AAC.00397-09. Epub 2009 Aug 3.


Drug-susceptible HIV-1 infection despite intermittent fixed-dose combination tenofovir/emtricitabine as prophylaxis is associated with low-level viremia, delayed seroconversion, and an attenuated clinical course.

Prada N, Davis B, Jean-Pierre P, La Roche M, Duh FM, Carrington M, Poles M, Mehandru S, Mohri H, Markowitz M.

J Acquir Immune Defic Syndr. 2008 Oct 1;49(2):117-22. doi: 10.1097/QAI.0b013e3181869a9b.


In vitro characterization of multidrug-resistant HIV-1 isolates from a recently infected patient associated with dual tropism and rapid disease progression.

Mohri H, Markowitz M.

J Acquir Immune Defic Syndr. 2008 Aug 15;48(5):511-21. doi: 10.1097/QAI.0b013e31817ecb31.


[Effective immunosuppresive therapies including steroid pulse treatment for intramuscular hematoma in iliopsoas in acquired hemophilia].

Mohri H, Tanabe J, Takagi H, Murata T.

Rinsho Ketsueki. 2007 Dec;48(12):1544-8. Japanese.


[IgG-kappa type multiple myeloma with cytoplasmic crystalline inclusions].

Kobayashi C, Tanabe J, Aoki M, Suzuuki R, Asai H, Kurita M, Murata T, Mohri H.

Rinsho Ketsueki. 2007 Aug;48(8):652-8. Review. Japanese.


Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection.

Mehandru S, Vcelar B, Wrin T, Stiegler G, Joos B, Mohri H, Boden D, Galovich J, Tenner-Racz K, Racz P, Carrington M, Petropoulos C, Katinger H, Markowitz M.

J Virol. 2007 Oct;81(20):11016-31. Epub 2007 Aug 8.


Efficient repeated low-dose intravaginal infection with X4 and R5 SHIVs in rhesus macaque: implications for HIV-1 transmission in humans.

Tsai L, Trunova N, Gettie A, Mohri H, Bohm R, Saifuddin M, Cheng-Mayer C.

Virology. 2007 May 25;362(1):207-16. Epub 2007 Jan 29.


Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection.

Mehandru S, Poles MA, Tenner-Racz K, Jean-Pierre P, Manuelli V, Lopez P, Shet A, Low A, Mohri H, Boden D, Racz P, Markowitz M.

PLoS Med. 2006 Dec;3(12):e484. Erratum in: PLoS Med. 2006 Dec;3(12):e546.


Mechanisms of gastrointestinal CD4+ T-cell depletion during acute and early human immunodeficiency virus type 1 infection.

Mehandru S, Poles MA, Tenner-Racz K, Manuelli V, Jean-Pierre P, Lopez P, Shet A, Low A, Mohri H, Boden D, Racz P, Markowitz M.

J Virol. 2007 Jan;81(2):599-612. Epub 2006 Oct 25.


Acquired von Willebrand syndrome: features and management.

Mohri H.

Am J Hematol. 2006 Aug;81(8):616-23. Review.


Hyperactivation of monkey spermatozoa is triggered by Ca2+ and completed by cAMP.

Ishijima S, Mohri H, Overstreet JW, Yudin AI.

Mol Reprod Dev. 2006 Sep;73(9):1129-39.


Tracking the prevalence of transmitted antiretroviral drug-resistant HIV-1: a decade of experience.

Shet A, Berry L, Mohri H, Mehandru S, Chung C, Kim A, Jean-Pierre P, Hogan C, Simon V, Boden D, Markowitz M.

J Acquir Immune Defic Syndr. 2006 Apr 1;41(4):439-46.


Analysis of hallucinogenic constituents in Amanita mushrooms circulated in Japan.

Tsujikawa K, Mohri H, Kuwayama K, Miyaguchi H, Iwata Y, Gohda A, Fukushima S, Inoue H, Kishi T.

Forensic Sci Int. 2006 Dec 20;164(2-3):172-8. Epub 2006 Feb 7.


Infection with multidrug resistant, dual-tropic HIV-1 and rapid progression to AIDS: a case report.

Markowitz M, Mohri H, Mehandru S, Shet A, Berry L, Kalyanaraman R, Kim A, Chung C, Jean-Pierre P, Horowitz A, La Mar M, Wrin T, Parkin N, Poles M, Petropoulos C, Mullen M, Boden D, Ho DD.

Lancet. 2005 Mar 19-25;365(9464):1031-8.


Resolution of acquired factor X deficiency with amyloidosis secondary to plasma cell dyscrasia.

Mohri H.

Am J Hematol. 2004 Dec;77(4):421-2. No abstract available.


Acquired von Willebrand syndrome: its pathophysiology, laboratory features and management.

Mohri H.

J Thromb Thrombolysis. 2003 Jun;15(3):141-9. Review.


Ultrastructure and function of long and short sperm in Cicadidae (Hemiptera).

Kubo-Irie M, Irie M, Nakazawa T, Mohri H.

J Insect Physiol. 2003 Nov;49(11):983-91.


Timing of anti-platelet effect after oral aspirin administration in patients with sympathetic excitement.

Nishiyama A, Niikawa O, Mohri H, Tsushima M.

Circ J. 2003 Aug;67(8):697-700.


Estimating average cellular turnover from 5-bromo-2'-deoxyuridine (BrdU) measurements.

De Boer RJ, Mohri H, Ho DD, Perelson AS.

Proc Biol Sci. 2003 Apr 22;270(1517):849-58.


In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?

Ribeiro RM, Mohri H, Ho DD, Perelson AS.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15572-7. Epub 2002 Nov 14.


Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells.

Mishima A, Suzuki A, Enaka M, Hirose T, Mizuno K, Ohnishi T, Mohri H, Ishigatsubo Y, Ohno S.

Genes Cells. 2002 Jun;7(6):581-96.


Magnetic resonance imaging of deep vein thrombus.

Nishiyama A, Kurata Y, Niikawa O, Mohri H, Koizumi J, Kunieda T.

Can J Cardiol. 2002 May;18(5):543. No abstract available.


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