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Items: 1 to 50 of 68

1.

A novel interaction of PAK4 with PPARγ to regulate Nox1 and radiation-induced epithelial-to-mesenchymal transition in glioma.

Kesanakurti D, Maddirela D, Banasavadi-Siddegowda YK, Lai TH, Qamri Z, Jacob NK, Sampath D, Mohanam S, Kaur B, Puduvalli VK.

Oncogene. 2017 Sep 14;36(37):5309-5320. doi: 10.1038/onc.2016.261. Epub 2017 May 22.

2.

Correction: Intermittent Hypoxia Effect on Osteoclastogenesis Stimulated by Neuroblastoma Cells.

Bhaskara VK, Mohanam I, Gujrati M, Mohanam S.

PLoS One. 2017 Jan 13;12(1):e0170156. doi: 10.1371/journal.pone.0170156. eCollection 2017.

3.

Intermittent hypoxia effect on osteoclastogenesis stimulated by neuroblastoma cells.

Bhaskara VK, Mohanam I, Gujrati M, Mohanam S.

PLoS One. 2014 Aug 22;9(8):e105555. doi: 10.1371/journal.pone.0105555. eCollection 2014. Erratum in: PLoS One. 2017 Jan 13;12 (1):e0170156. Retraction in: PLoS One. 2018 Jun 5;13(6):e0198763.

4.

Intermittent hypoxia regulates stem-like characteristics and differentiation of neuroblastoma cells.

Bhaskara VK, Mohanam I, Rao JS, Mohanam S.

PLoS One. 2012;7(2):e30905. doi: 10.1371/journal.pone.0030905. Epub 2012 Feb 17.

5.

Mechanism of p27 upregulation induced by downregulation of cathepsin B and uPAR in glioma.

Gopinath S, Alapati K, Malla RR, Gondi CS, Mohanam S, Dinh DH, Rao JS.

Mol Oncol. 2011 Oct;5(5):426-37. doi: 10.1016/j.molonc.2011.07.004. Epub 2011 Jul 26.

6.

Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT.

Asuthkar S, Nalla AK, Gondi CS, Dinh DH, Gujrati M, Mohanam S, Rao JS.

Neuro Oncol. 2011 Oct;13(10):1059-73. doi: 10.1093/neuonc/nor109. Epub 2011 Aug 2.

7.

α3β1 integrin promotes radiation-induced migration of meningioma cells.

Gogineni VR, Nalla AK, Gupta R, Gujrati M, Klopfenstein JD, Mohanam S, Rao JS.

Int J Oncol. 2011 Jun;38(6):1615-24. doi: 10.3892/ijo.2011.987. Epub 2011 Mar 29.

8.

Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1.

Velpula KK, Dasari VR, Tsung AJ, Gondi CS, Klopfenstein JD, Mohanam S, Rao JS.

PLoS One. 2011 Mar 24;6(3):e18017. doi: 10.1371/journal.pone.0018017.

9.

uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.

Gupta R, Nalla AK, Gogineni VR, Chetty C, Bhoopathi P, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS.

PLoS One. 2011 Feb 11;6(2):e17123. doi: 10.1371/journal.pone.0017123.

10.

Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo.

Gupta R, Rao Gogineni V, Nalla AK, Chetty C, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS.

Int J Oncol. 2011 Apr;38(4):973-83. doi: 10.3892/ijo.2011.934. Epub 2011 Feb 2.

11.

Downregulation of uPA/uPAR inhibits intermittent hypoxia-induced epithelial-mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells.

Gupta R, Chetty C, Bhoopathi P, Lakka S, Mohanam S, Rao JS, Dinh DE.

Int J Oncol. 2011 Mar;38(3):733-44. doi: 10.3892/ijo.2010.883. Epub 2010 Dec 22.

PMID:
21181094
12.

siRNA-mediated downregulation of MMP-9 and uPAR in combination with radiation induces G2/M cell-cycle arrest in Medulloblastoma.

Nagaraju GP, Nalla AK, Gupta R, Mohanam S, Gujrati M, Dinh DH, Rao JS.

Mol Cancer Res. 2011 Jan;9(1):51-66. doi: 10.1158/1541-7786.MCR-10-0399. Epub 2010 Dec 10.

13.

Downregulation of Focal Adhesion Kinase (FAK) by cord blood stem cells inhibits angiogenesis in glioblastoma.

Dasari VR, Kaur K, Velpula KK, Dinh DH, Tsung AJ, Mohanam S, Rao JS.

Aging (Albany NY). 2010 Nov;2(11):791-803.

14.

Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas.

Malla R, Gopinath S, Alapati K, Gondi CS, Gujrati M, Dinh DH, Mohanam S, Rao JS.

PLoS One. 2010 Oct 29;5(10):e13731. doi: 10.1371/journal.pone.0013731.

15.

Suppression of uPA and uPAR attenuates angiogenin mediated angiogenesis in endothelial and glioblastoma cell lines.

Raghu H, Lakka SS, Gondi CS, Mohanam S, Dinh DH, Gujrati M, Rao JS.

PLoS One. 2010 Aug 27;5(8):e12458. doi: 10.1371/journal.pone.0012458.

16.

The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice.

Ezhilarasan R, Jadhav U, Mohanam I, Rao JS, Gujrati M, Mohanam S.

Int J Cancer. 2009 Jan 15;124(2):306-15. doi: 10.1002/ijc.23951.

17.

Dietary isothiocyanate iberin inhibits growth and induces apoptosis in human glioblastoma cells.

Jadhav U, Ezhilarasan R, Vaughn SF, Berhow MA, Mohanam S.

J Pharmacol Sci. 2007 Feb;103(2):247-51.

18.

Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells.

Jadhav U, Ezhilarasan R, Vaughn SF, Berhow MA, Mohanam S.

Int J Mol Med. 2007 Mar;19(3):353-61.

19.

Glioma cells suppress hypoxia-induced endothelial cell apoptosis and promote the angiogenic process.

Ezhilarasan R, Mohanam I, Govindarajan K, Mohanam S.

Int J Oncol. 2007 Mar;30(3):701-7.

21.

Inhibition of matrix metalloproteinase-9 reduces in vitro invasion and angiogenesis in human microvascular endothelial cells.

Jadhav U, Chigurupati S, Lakka SS, Mohanam S.

Int J Oncol. 2004 Nov;25(5):1407-14.

PMID:
15492832
22.

Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis.

Yanamandra N, Gumidyala KV, Waldron KG, Gujrati M, Olivero WC, Dinh DH, Rao JS, Mohanam S.

Oncogene. 2004 Mar 18;23(12):2224-30.

PMID:
14730346
23.

Glial cell-induced endothelial morphogenesis is inhibited by interfering with extracellular signal-regulated kinase signaling.

Chandrasekar N, Mohanam S, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS.

Clin Cancer Res. 2003 Jun;9(6):2342-9.

24.

Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells.

Chandrasekar N, Mohanam S, Gujrati M, Olivero WC, Dinh DH, Rao JS.

Oncogene. 2003 Jan 23;22(3):392-400.

PMID:
12545160
25.

Modulation of invasive properties of human glioblastoma cells stably expressing amino-terminal fragment of urokinase-type plasminogen activator.

Mohanam S, Chandrasekar N, Yanamandra N, Khawar S, Mirza F, Dinh DH, Olivero WC, Rao JS.

Oncogene. 2002 Nov 7;21(51):7824-30.

26.

Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences.

Adachi Y, Chandrasekar N, Kin Y, Lakka SS, Mohanam S, Yanamandra N, Mohan PM, Fuller GN, Fang B, Fueyo J, Dinh DH, Olivero WC, Tamiya T, Ohmoto T, Kyritsis AP, Rao JS.

Oncogene. 2002 Jan 3;21(1):87-95.

27.

Downregulation of urokinase-type plasminogen activator receptor (uPAR) induces caspase-mediated cell death in human glioblastoma cells.

Yanamandra N, Konduri SD, Mohanam S, Dinh DH, Olivero WC, Gujrati M, Nicolson GL, Obeyeseke M, Rao JS.

Clin Exp Metastasis. 2000;18(7):611-5.

PMID:
11688967
28.

A novel function of tissue factor pathway inhibitor-2 (TFPI-2) in human glioma invasion.

Konduri SD, Rao CN, Chandrasekar N, Tasiou A, Mohanam S, Kin Y, Lakka SS, Dinh D, Olivero WC, Gujrati M, Foster DC, Kisiel W, Rao JS.

Oncogene. 2001 Oct 18;20(47):6938-45.

29.

Down-regulation of integrin alpha(v)beta(3) expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPAR) and sense p16 genes.

Adachi Y, Lakka SS, Chandrasekar N, Yanamandra N, Gondi CS, Mohanam S, Dinh DH, Olivero WC, Gujrati M, Tamiya T, Ohmoto T, Kouraklis G, Aggarwal B, Rao JS.

J Biol Chem. 2001 Dec 14;276(50):47171-7. Epub 2001 Sep 25.

30.

Stable transfection of urokinase-type plasminogen activator antisense construct modulates invasion of human glioblastoma cells.

Mohanam S, Jasti SL, Kondraganti SR, Chandrasekar N, Kin Y, Fuller GN, Lakka SS, Kyritsis AP, Dinh DH, Olivero WC, Gujrati M, Yung WK, Rao JS.

Clin Cancer Res. 2001 Aug;7(8):2519-26.

31.

Modulation of endothelial cell morphogenesis in vitro by MMP-9 during glial-endothelial cell interactions.

Chandrasekar N, Jasti S, Alfred-Yung WK, Ali-Osman F, Dinh DH, Olivero WC, Gujrati M, Kyritsis AP, Nicolson GL, Rao JS, Mohanam S.

Clin Exp Metastasis. 2000;18(4):337-42.

PMID:
11448065
32.

Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.

Mohanam S, Jasti SL, Kondraganti SR, Chandrasekar N, Lakka SS, Kin Y, Fuller GN, Yung AW, Kyritsis AP, Dinh DH, Olivero WC, Gujrati M, Ali-Osman F, Rao JS.

Oncogene. 2001 Jun 21;20(28):3665-73.

33.

In vitro modulation of human lung cancer cell line invasiveness by antisense cDNA of tissue factor pathway inhibitor-2.

Lakka SS, Konduri SD, Mohanam S, Nicolson GL, Rao JS.

Clin Exp Metastasis. 2000;18(3):239-44.

PMID:
11315097
34.

Expression of tissue factor pathway inhibitor 2 inversely correlates during the progression of human gliomas.

Rao CN, Lakka SS, Kin Y, Konduri SD, Fuller GN, Mohanam S, Rao JS.

Clin Cancer Res. 2001 Mar;7(3):570-6.

35.

Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines.

Bhattacharya A, Lakka SS, Mohanam S, Boyd D, Rao JS.

Clin Cancer Res. 2001 Feb;7(2):267-76.

36.

Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion.

Kondraganti S, Mohanam S, Chintala SK, Kin Y, Jasti SL, Nirmala C, Lakka SS, Adachi Y, Kyritsis AP, Ali-Osman F, Sawaya R, Fuller GN, Rao JS.

Cancer Res. 2000 Dec 15;60(24):6851-5.

37.

Regulation of the uPA gene in various grades of human glioma cells.

Lakka SS, Bhattacharya A, Mohanam S, Boyd D, Rao JS.

Int J Oncol. 2001 Jan;18(1):71-9.

PMID:
11115541
38.

Effects of radiation on the levels of MMP-2, MMP-9 and TIMP-1 during morphogenic glial-endothelial cell interactions.

Nirmala C, Jasti SL, Sawaya R, Kyritsis AP, Konduri SD, Ali-Osman F, Rao JS, Mohanam S.

Int J Cancer. 2000 Dec 1;88(5):766-71.

39.

A novel role for the urokinase-type plasminogen activator receptor in apoptosis of malignant gliomas.

Kin Y, Chintala SK, Go Y, Sawaya R, Mohanam S, Kyritsis AP, Rao JS.

Int J Oncol. 2000 Jul;17(1):61-5.

PMID:
10853019
40.

Downregulation of the urokinase-type plasminogen activator receptor through inhibition of translation by antisense oligonucleotide suppresses invasion of human glioblastoma cells.

Mohan PM, Lakka SS, Mohanam S, Kin Y, Sawaya R, Kyritsis AP, Nicolson GL, Rao JS.

Clin Exp Metastasis. 1999;17(7):617-21.

PMID:
10845561
41.

Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.

Chintala SK, Kyritsis AP, Mohan PM, Mohanam S, Sawaya R, Gokslan Z, Yung WK, Steck P, Uhm JH, Aggarwal BB, Rao JS.

Mol Carcinog. 1999 Dec;26(4):274-85.

PMID:
10569804
42.

Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth.

Mohan PM, Chintala SK, Mohanam S, Gladson CL, Kim ES, Gokaslan ZL, Lakka SS, Roth JA, Fang B, Sawaya R, Kyritsis AP, Rao JS.

Cancer Res. 1999 Jul 15;59(14):3369-73.

43.

Regulation of ProMMP-1 and ProMMP-3 activation by tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor.

Rao CN, Mohanam S, Puppala A, Rao JS.

Biochem Biophys Res Commun. 1999 Feb 5;255(1):94-8. Erratum in: Biochem Biophys Res Commun 1999 May 10;258(2):497.

PMID:
10082661
44.

Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors.

Mohanam S, Gladson CL, Rao CN, Rao JS.

Front Biosci. 1999 Feb 15;4:D178-87. Review.

PMID:
9989951
45.

Elevated levels of urokinase-type plasminogen activator and its receptor during tumor growth in vivo.

Mohanam S, Go Y, Sawaya R, Venkaiah B, Mohan PM, Kouraklis GP, Gokaslan ZL, Lagos GK, Rao JS.

Int J Oncol. 1999 Jan;14(1):169-74.

PMID:
9863025
46.

Increased invasion of neuroglioma cells transfected with urokinase plasminogen activator receptor cDNA.

Mohanam S, Chintala SK, Mohan PM, Sawaya R, Lagos GK, Gokaslan ZL, Kouraklis GP, Rao JS.

Int J Oncol. 1998 Dec;13(6):1285-90.

PMID:
9824646
47.

Elevated levels of Mr 92,000 type IV collagenase during tumor growth in vivo.

Sawaya R, Go Y, Kyritisis AP, Uhm J, Venkaiah B, Mohanam S, Gokaslan ZL, Rao JS.

Biochem Biophys Res Commun. 1998 Oct 20;251(2):632-6.

PMID:
9792825
48.

Altered in vitro spreading and cytoskeletal organization in human glioma cells by downregulation of urokinase receptor.

Chintala SK, Mohanam S, Go Y, Venkaiah B, Sawaya R, Gokaslan ZL, Rao JS.

Mol Carcinog. 1997 Dec;20(4):355-65.

PMID:
9433480
49.

Inhibition of in vivo tumorigenicity and invasiveness of a human glioblastoma cell line transfected with antisense uPAR vectors.

Go Y, Chintala SK, Mohanam S, Gokaslan Z, Venkaiah B, Bjerkvig R, Oka K, Nicolson GL, Sawaya R, Rao JS.

Clin Exp Metastasis. 1997 Jul;15(4):440-6.

PMID:
9219733
50.

Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro.

Chintala SK, Ali-Osman F, Mohanam S, Rayford A, Go Y, Gokaslan ZL, Gagercas E, Venkaiah B, Sawaya R, Nicolson GL, Rao JS.

Clin Exp Metastasis. 1997 Jul;15(4):361-7.

PMID:
9219724

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