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Items: 1 to 50 of 460

1.

Clinical relevance of lung-restricted antibodies in lung transplantation.

Akbarpour M, Wu Q, Liu X, Sun H, Lecuona E, Tomic R, Bhorade S, Mohanakumar T, Bharat A.

Hum Immunol. 2019 May 8. pii: S0198-8859(19)30203-4. doi: 10.1016/j.humimm.2019.04.016. [Epub ahead of print] Review.

PMID:
31078336
2.

Development and Optimization of an ELISA to Quantitate C3(H 2 O) as a Marker of Human Disease.

Elvington M, Liszewski MK, Liszewski AR, Kulkarni HS, Hachem RR, Mohanakumar T, Kim AHJ, Atkinson JP.

Front Immunol. 2019 Apr 4;10:703. doi: 10.3389/fimmu.2019.00703. eCollection 2019.

3.

The role of donor-derived exosomes in lung allograft rejection.

Ravichandran R, Bansal S, Rahman M, Sharma M, Liu W, Bharat A, Hachem R, Omar A, Smith MA, Mohanakumar T.

Hum Immunol. 2019 Mar 18. pii: S0198-8859(19)30140-5. doi: 10.1016/j.humimm.2019.03.012. [Epub ahead of print] Review.

PMID:
30898684
4.

Prevalence of antibodies to lung self-antigens (Kα1 tubulin and collagen V) and donor specific antibodies to HLA in lung transplant recipients and implications for lung transplant outcomes: Single center experience.

Rao U, Sharma M, Mohanakumar T, Ahn C, Gao A, Kaza V.

Transpl Immunol. 2019 Jun;54:65-72. doi: 10.1016/j.trim.2019.02.006. Epub 2019 Feb 20.

PMID:
30794945
5.

Association between Allosensitization and Waiting List Outcomes among Adult Lung Transplant Candidates in the United States.

Tague LK, Witt CA, Byers DE, Yusen RD, Aguilar PR, Kulkarni HS, Bain KB, Fester KA, Puri V, Kreisel D, Mohanakumar T, Trulock EP, Hachem RR.

Ann Am Thorac Soc. 2019 Feb 14. doi: 10.1513/AnnalsATS.201810-713OC. [Epub ahead of print]

PMID:
30763122
6.

The detection of donor-derived cell-free DNA may serve as a biomarker for the early detection of chronic lung allograft dysfunction.

Bansal S, Fleming T, Mohanakumar T.

EBioMedicine. 2019 Feb;40:13-14. doi: 10.1016/j.ebiom.2019.01.044. Epub 2019 Feb 5. No abstract available.

7.

Molecular events contributing to successful pediatric cardiac transplantation in HLA sensitized recipients.

Sharma M, Webber SA, Zeevi A, Mohanakumar T.

Hum Immunol. 2019 Apr;80(4):248-256. doi: 10.1016/j.humimm.2019.01.008. Epub 2019 Jan 30.

PMID:
30710563
8.

Neutrophil extracellular trap fragments stimulate innate immune responses that prevent lung transplant tolerance.

Scozzi D, Wang X, Liao F, Liu Z, Zhu J, Pugh K, Ibrahim M, Hsiao HM, Miller MJ, Yizhan G, Mohanakumar T, Krupnick AS, Kreisel D, Gelman AE.

Am J Transplant. 2019 Apr;19(4):1011-1023. doi: 10.1111/ajt.15163. Epub 2018 Dec 13.

PMID:
30378766
9.

Tissue-associated self-antigens containing exosomes: Role in allograft rejection.

Sharma M, Ravichandran R, Bansal S, Bremner RM, Smith MA, Mohanakumar T.

Hum Immunol. 2018 Sep;79(9):653-658. doi: 10.1016/j.humimm.2018.06.005. Epub 2018 Jun 15.

PMID:
29908844
10.

The role of exosomes in allograft immunity.

Bansal S, Sharma M, R R, Mohanakumar T.

Cell Immunol. 2018 Sep;331:85-92. doi: 10.1016/j.cellimm.2018.06.003. Epub 2018 Jun 7. Review.

PMID:
29907298
11.

Isolation and In Vitro Culture of Murine and Human Alveolar Macrophages.

Nayak DK, Mendez O, Bowen S, Mohanakumar T.

J Vis Exp. 2018 Apr 20;(134). doi: 10.3791/57287.

12.

Human leukocyte antigens antibodies after lung transplantation: Primary results of the HALT study.

Hachem RR, Kamoun M, Budev MM, Askar M, Ahya VN, Lee JC, Levine DJ, Pollack MS, Dhillon GS, Weill D, Schechtman KB, Leard LE, Golden JA, Baxter-Lowe L, Mohanakumar T, Tyan DB, Yusen RD.

Am J Transplant. 2018 Sep;18(9):2285-2294. doi: 10.1111/ajt.14893. Epub 2018 May 15.

PMID:
29687961
13.

Circulating Exosomes with Distinct Properties during Chronic Lung Allograft Rejection.

Gunasekaran M, Sharma M, Hachem R, Bremner R, Smith MA, Mohanakumar T.

J Immunol. 2018 Apr 15;200(8):2535-2541. doi: 10.4049/jimmunol.1701587. Epub 2018 Feb 28.

14.

Study rationale, design, and pretransplantation alloantibody status: A first report of Clinical Trials in Organ Transplantation in Children-04 (CTOTC-04) in pediatric heart transplantation.

Zuckerman WA, Zeevi A, Mason KL, Feingold B, Bentlejewski C, Addonizio LJ, Blume ED, Canter CE, Dipchand AI, Hsu DT, Shaddy RE, Mahle WT, Demetris AJ, Briscoe DM, Mohanakumar T, Ahearn JM, Iklé DN, Armstrong BD, Morrison Y, Diop H, Odim J, Webber SA.

Am J Transplant. 2018 Sep;18(9):2135-2147. doi: 10.1111/ajt.14695. Epub 2018 Mar 23.

PMID:
29446208
15.

Exosomes expressing the self-antigens myosin and vimentin play an important role in syngeneic cardiac transplant rejection induced by antibodies to cardiac myosin.

Sharma M, Liu W, Perincheri S, Gunasekaran M, Mohanakumar T.

Am J Transplant. 2018 Jul;18(7):1626-1635. doi: 10.1111/ajt.14650. Epub 2018 Feb 14.

PMID:
29316217
16.

Lung Retransplantation for Chronic Rejection: A Single-Center Experience.

Biswas Roy S, Panchanathan R, Walia R, Varsch KE, Kang P, Huang J, Hashimi AS, Mohanakumar T, Bremner RM, Smith MA.

Ann Thorac Surg. 2018 Jan;105(1):221-227. doi: 10.1016/j.athoracsur.2017.07.025. Epub 2017 Nov 1.

PMID:
29100649
17.

Accelerated humoral renal allograft rejection due to HLA-C14 mediated allosensitization to HLA-Bw6.

Persaud SP, Duffy B, Phelan DL, Mohanakumar T, Delos Santos R, Gaut JP, Liu C.

Hum Immunol. 2017 Nov;78(11-12):692-698. doi: 10.1016/j.humimm.2017.09.004. Epub 2017 Oct 9.

PMID:
29024716
18.

The role of C4d deposition in the diagnosis of antibody-mediated rejection after lung transplantation.

Aguilar PR, Carpenter D, Ritter J, Yusen RD, Witt CA, Byers DE, Mohanakumar T, Kreisel D, Trulock EP, Hachem RR.

Am J Transplant. 2018 Apr;18(4):936-944. doi: 10.1111/ajt.14534. Epub 2017 Nov 11.

19.

Immunoglobulin isotype switching of antibodies to vimentin is associated with development of transplant glomerulopathy following human renal transplantation.

Gunasekaran M, Maw TT, Santos RD, Shenoy S, Wellen J, Mohanakumar T.

Transpl Immunol. 2017 Dec;45:42-47. doi: 10.1016/j.trim.2017.09.001. Epub 2017 Sep 11.

PMID:
28911876
20.

Quantitative Evaluation of the Impact of Ethylenediaminetetraacetic Acid Pretreatment on Single-Antigen Bead Assay.

Liu C, Pang S, Phelan D, Brennan DC, Mohanakumar T.

Transplant Direct. 2017 Jul 11;3(8):e194. doi: 10.1097/TXD.0000000000000709. eCollection 2017 Aug.

21.

New Answers to Old Conundrums: What Antibodies, Exosomes and Inflammasomes Bring to the Conversation. Canadian National Transplant Research Program International Summit Report.

Dieudé M, West LJ, Muruve DA, Gunaratnam L, Mohanakumar T, Zorn E, Cairo CW, Freed DH, Schultz KR, Fairchild RL, Hébert MJ.

Transplantation. 2018 Feb;102(2):209-214. doi: 10.1097/TP.0000000000001872. Review. Erratum in: Transplantation. 2018 Jul;102(7):e360. Gunaratman, Lakshman [corrected to Gunaratnam, Lakshman].

22.

Zbtb7a induction in alveolar macrophages is implicated in anti-HLA-mediated lung allograft rejection.

Nayak DK, Zhou F, Xu M, Huang J, Tsuji M, Yu J, Hachem R, Gelman AE, Bremner RM, Smith MA, Mohanakumar T.

Sci Transl Med. 2017 Jul 12;9(398). pii: eaal1243. doi: 10.1126/scitranslmed.aal1243.

23.

Development of immune response to tissue-restricted self-antigens in simultaneous kidney-pancreas transplant recipients with acute rejection.

Gunasekaran M, Vachharajani N, Gaut JP, Maw TT, Delos Santos R, Shenoy S, Chapman WC, Wellen J, Mohanakumar T.

Clin Transplant. 2017 Aug;31(8). doi: 10.1111/ctr.13009. Epub 2017 Jun 21.

PMID:
28639386
24.

Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop.

Lama VN, Belperio JA, Christie JD, El-Chemaly S, Fishbein MC, Gelman AE, Hancock WW, Keshavjee S, Kreisel D, Laubach VE, Looney MR, McDyer JF, Mohanakumar T, Shilling RA, Panoskaltsis-Mortari A, Wilkes DS, Eu JP, Nicolls MR.

JCI Insight. 2017 May 4;2(9). pii: 93121. doi: 10.1172/jci.insight.93121. eCollection 2017 May 4. Review.

25.

Rapid detection of donor cell free DNA in lung transplant recipients with rejections using donor-recipient HLA mismatch.

Zou J, Duffy B, Slade M, Young AL, Steward N, Hachem R, Mohanakumar T.

Hum Immunol. 2017 Apr;78(4):342-349. doi: 10.1016/j.humimm.2017.03.002. Epub 2017 Mar 4.

26.

Untreated donor specific antibodies against HLA are associated with poor outcomes in peripheral blood haploidentical hematopoietic cell transplantation.

Zou J, Romee R, Slade M, Phelan D, Keller J, Mohanakumar T, Grossman BJ.

Bone Marrow Transplant. 2017 Jun;52(6):898-901. doi: 10.1038/bmt.2017.7. Epub 2017 Feb 20. No abstract available.

27.

Immune Responses to Tissue-Restricted Nonmajor Histocompatibility Complex Antigens in Allograft Rejection.

Bharat A, Mohanakumar T.

J Immunol Res. 2017;2017:6312514. doi: 10.1155/2017/6312514. Epub 2017 Jan 9. Review.

28.

Autologous and Allogenous Antibodies in Lung and Islet Cell Transplantation.

Nayak DK, Saravanan PB, Bansal S, Naziruddin B, Mohanakumar T.

Front Immunol. 2016 Dec 23;7:650. doi: 10.3389/fimmu.2016.00650. eCollection 2016. Review.

29.

Role of Circulating MicroRNAs in the Immunopathogenesis of Rejection After Pediatric Lung Transplantation.

Xu Z, Yang W, Steward N, Sweet SC, Danziger-Isakov L, Heeger PS, Mohanakumar T.

Transplantation. 2017 Oct;101(10):2461-2468. doi: 10.1097/TP.0000000000001595.

30.

Polyomavirus Reactivation and Immune Responses to Kidney-Specific Self-Antigens in Transplantation.

Seifert ME, Gunasekaran M, Horwedel TA, Daloul R, Storch GA, Mohanakumar T, Brennan DC.

J Am Soc Nephrol. 2017 Apr;28(4):1314-1325. doi: 10.1681/ASN.2016030285. Epub 2016 Nov 7.

31.

Significant role for microRNA-21 affecting toll-like receptor pathway in primary graft dysfunction after human lung transplantation.

Xu Z, Sharma M, Gelman A, Hachem R, Mohanakumar T.

J Heart Lung Transplant. 2017 Mar;36(3):331-339. doi: 10.1016/j.healun.2016.08.028. Epub 2016 Sep 12.

32.

Humoral Human Lung Allograft Rejection by Tissue-Restricted Non-HLA Antibodies.

Fernandez R, Chiu S, Raparia K, Garcha P, Farver C, Budev M, Tambur AR, DeCamp MM, Budinger S, Perlman H, Mohanakumar T, Bharat A.

Ann Thorac Surg. 2016 Oct;102(4):e339-41. doi: 10.1016/j.athoracsur.2016.03.042.

33.

Attenuation of Ischemia-Reperfusion Injury and Improvement of Survival in Recipients of Steatotic Rat Livers Using CD47 Monoclonal Antibody.

Xiao Z, Banan B, Xu M, Jia J, Manning PT, Hiebsch RR, Gunasekaran M, Upadhya GA, Frazier WA, Mohanakumar T, Lin Y, Chapman WC.

Transplantation. 2016 Jul;100(7):1480-9. doi: 10.1097/TP.0000000000001186.

PMID:
27331362
34.

Donor-Derived Exosomes With Lung Self-Antigens in Human Lung Allograft Rejection.

Gunasekaran M, Xu Z, Nayak DK, Sharma M, Hachem R, Walia R, Bremner RM, Smith MA, Mohanakumar T.

Am J Transplant. 2017 Feb;17(2):474-484. doi: 10.1111/ajt.13915. Epub 2016 Jul 16.

35.

2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.

Demetris AJ, Bellamy C, Hübscher SG, O'Leary J, Randhawa PS, Feng S, Neil D, Colvin RB, McCaughan G, Fung JJ, Del Bello A, Reinholt FP, Haga H, Adeyi O, Czaja AJ, Schiano T, Fiel MI, Smith ML, Sebagh M, Tanigawa RY, Yilmaz F, Alexander G, Baiocchi L, Balasubramanian M, Batal I, Bhan AK, Bucuvalas J, Cerski CTS, Charlotte F, de Vera ME, ElMonayeri M, Fontes P, Furth EE, Gouw ASH, Hafezi-Bakhtiari S, Hart J, Honsova E, Ismail W, Itoh T, Jhala NC, Khettry U, Klintmalm GB, Knechtle S, Koshiba T, Kozlowski T, Lassman CR, Lerut J, Levitsky J, Licini L, Liotta R, Mazariegos G, Minervini MI, Misdraji J, Mohanakumar T, Mölne J, Nasser I, Neuberger J, O'Neil M, Pappo O, Petrovic L, Ruiz P, Sağol Ö, Sanchez Fueyo A, Sasatomi E, Shaked A, Shiller M, Shimizu T, Sis B, Sonzogni A, Stevenson HL, Thung SN, Tisone G, Tsamandas AC, Wernerson A, Wu T, Zeevi A, Zen Y.

Am J Transplant. 2016 Oct;16(10):2816-2835. doi: 10.1111/ajt.13909. Epub 2016 Jul 14.

36.

Respiratory virus infections and chronic lung allograft dysfunction: Assessment of virology determinants.

Fisher CE, Mohanakumar T, Limaye AP.

J Heart Lung Transplant. 2016 Jul;35(7):946-7. doi: 10.1016/j.healun.2016.04.004. Epub 2016 May 11. No abstract available.

PMID:
27235268
37.

Lung Injury Combined with Loss of Regulatory T Cells Leads to De Novo Lung-Restricted Autoimmunity.

Chiu S, Fernandez R, Subramanian V, Sun H, DeCamp MM, Kreisel D, Perlman H, Budinger GR, Mohanakumar T, Bharat A.

J Immunol. 2016 Jul 1;197(1):51-7. doi: 10.4049/jimmunol.1502539. Epub 2016 May 18.

38.

Lung-Restricted Antibodies Mediate Primary Graft Dysfunction and Prevent Allotolerance after Murine Lung Transplantation.

Bharat A, Chiu S, Zheng Z, Sun H, Yeldandi A, DeCamp MM, Perlman H, Budinger GR, Mohanakumar T.

Am J Respir Cell Mol Biol. 2016 Oct;55(4):532-541.

39.

Long-Term Persistence of Donor Alveolar Macrophages in Human Lung Transplant Recipients That Influences Donor-Specific Immune Responses.

Nayak DK, Zhou F, Xu M, Huang J, Tsuji M, Hachem R, Mohanakumar T.

Am J Transplant. 2016 Aug;16(8):2300-11. doi: 10.1111/ajt.13819. Epub 2016 May 23.

40.

MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndrome.

Xu Z, Ramachandran S, Gunasekaran M, Zhou F, Trulock E, Kreisel D, Hachem R, Mohanakumar T.

J Heart Lung Transplant. 2016 Apr;35(4):543-4. doi: 10.1016/j.healun.2016.01.022. Epub 2016 Mar 3. No abstract available.

PMID:
27044533
41.

Cardiac antibody production to self-antigens in children and adolescents during and following the correction of severe diabetic ketoacidosis.

Hoffman WH, Sharma M, Cihakova D, Talor MV, Rose NR, Mohanakumar T, Passmore GG.

Autoimmunity. 2016;49(3):188-96. doi: 10.3109/08916934.2015.1134509. Epub 2016 Feb 25.

PMID:
26911924
42.

B Cell-Activating Transcription Factor Plays a Critical Role in the Pathogenesis of Anti-Major Histocompatibility Complex-Induced Obliterative Airway Disease.

Xu Z, Ramachandran S, Gunasekaran M, Nayak D, Benshoff N, Hachem R, Gelman A, Mohanakumar T.

Am J Transplant. 2016 Apr;16(4):1173-82. doi: 10.1111/ajt.13595. Epub 2016 Feb 4.

43.

Maternal T-Cell Engraftment Interferes With Human Leukocyte Antigen Typing in Severe Combined Immunodeficiency.

Liu C, Duffy B, Bednarski JJ, Calhoun C, Lay L, Rundblad B, Payton JE, Mohanakumar T.

Am J Clin Pathol. 2016 Feb;145(2):251-7. doi: 10.1093/ajcp/aqv079. Epub 2016 Feb 1.

44.

ABO incompatible renal transplants and decreased likelihood for developing immune responses to HLA and kidney self-antigens.

Subramanian V, Gunasekaran M, Gaut JP, Phelan D, Vachharajani N, Santos RD, Wellen J, Shenoy S, Mohanakumar T.

Hum Immunol. 2016 Jan;77(1):76-83. doi: 10.1016/j.humimm.2015.10.014. Epub 2015 Oct 22.

PMID:
26476207
45.

Novel strategy to decrease reperfusion injuries and improve function of cold-preserved livers using normothermic ex vivo liver perfusion machine.

Banan B, Xiao Z, Watson R, Xu M, Jia J, Upadhya GA, Mohanakumar T, Lin Y, Chapman W.

Liver Transpl. 2016 Mar;22(3):333-43. doi: 10.1002/lt.24352. Epub 2016 Feb 15.

46.

Normothermic extracorporeal liver perfusion for donation after cardiac death (DCD) livers.

Banan B, Chung H, Xiao Z, Tarabishy Y, Jia J, Manning P, Upadhya GA, Mohanakumar T, Lin Y, Chapman WC.

Surgery. 2015 Dec;158(6):1642-50. doi: 10.1016/j.surg.2015.07.016. Epub 2015 Aug 18.

PMID:
26294088
47.

The impact of pre-transplant allosensitization on outcomes after lung transplantation.

Bosanquet JP, Witt CA, Bemiss BC, Byers DE, Yusen RD, Patterson AG, Kreisel D, Mohanakumar T, Trulock EP, Hachem RR.

J Heart Lung Transplant. 2015 Nov;34(11):1415-22. doi: 10.1016/j.healun.2015.06.003. Epub 2015 Jun 10.

48.

De novo development of antibodies to kidney-associated self-antigens angiotensin II receptor type I, collagen IV, and fibronectin occurs at early time points after kidney transplantation in children.

Hesemann LE, Subramanian V, Mohanakumar T, Dharnidharka VR.

Pediatr Transplant. 2015 Aug;19(5):499-503. doi: 10.1111/petr.12531. Epub 2015 Jun 9.

49.

MicroRNA-144 dysregulates the transforming growth factor-β signaling cascade and contributes to the development of bronchiolitis obliterans syndrome after human lung transplantation.

Xu Z, Ramachandran S, Gunasekaran M, Zhou F, Trulock E, Kreisel D, Hachem R, Mohanakumar T.

J Heart Lung Transplant. 2015 Sep;34(9):1154-62. doi: 10.1016/j.healun.2015.03.021. Epub 2015 Mar 27.

50.

De novo-developed antibodies to donor MHC antigens lead to dysregulation of microRNAs and induction of MHC class II.

Xu Z, Nayak DK, Benshoff N, Hachem R, Gelman AE, Mohanakumar T.

J Immunol. 2015 Jun 15;194(12):6133-43. doi: 10.4049/jimmunol.1401848. Epub 2015 May 4.

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