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Items: 1 to 50 of 83

1.

Identification of calcium, sodium, magnesium and chloride ion levels in hypertensive and non-hypertensive trinidadians.

Gadad A, Mohammed S, Sundaram V, Nayak SB, Mohammed AR, Ramnanansingh TG.

Int J Biochem Mol Biol. 2019 Aug 15;10(3):17-22. eCollection 2019.

2.

Conceptualisation, Development, Fabrication and In Vivo Validation of a Novel Disintegration Tester for Orally Disintegrating Tablets.

Koner JS, Rajabi-Siahboomi AR, Missaghi S, Kirby D, Perrie Y, Ahmed J, Mohammed AR.

Sci Rep. 2019 Aug 28;9(1):12467. doi: 10.1038/s41598-019-48859-x.

3.

LC-MS/MS method for quantification of 3,4-dihydroxyphenylglycol, a norepinephrine metabolite in plasma and brain regions.

Padala NSP, Ajjala DR, Boggavarapu RK, Pantangi HR, Thentu JB, Mohammed AR, Nirogi R.

Bioanalysis. 2019 May;11(10):971-986. doi: 10.4155/bio-2019-0023.

PMID:
31218903
4.

Delivery of Poorly Soluble Drugs via Mesoporous Silica: Impact of Drug Overloading on Release and Thermal Profiles.

Le TT, Elzhry Elyafi AK, Mohammed AR, Al-Khattawi A.

Pharmaceutics. 2019 Jun 10;11(6). pii: E269. doi: 10.3390/pharmaceutics11060269.

5.

Investigating the blood-host plasticity and dispersal of Anopheles coluzzii using a novel field-based methodology.

Orsborne J, Furuya-Kanamori L, Jeffries CL, Kristan M, Mohammed AR, Afrane YA, O'Reilly K, Massad E, Drakeley C, Walker T, Yakob L.

Parasit Vectors. 2019 Mar 25;12(1):143. doi: 10.1186/s13071-019-3401-3.

6.

High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport.

Pollard J, Rajabi-Siahboomi A, Badhan RKS, Mohammed AR, Perrie Y.

J Pharm Pharmacol. 2019 Jun;71(6):889-897. doi: 10.1111/jphp.13072. Epub 2019 Feb 19.

7.

Discovery and Development of N-[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Active Histamine H3 Receptor Inverse Agonist with Robust Wake-Promoting Activity.

Nirogi R, Shinde A, Mohammed AR, Badange RK, Reballi V, Bandyala TR, Saraf SK, Bojja K, Manchineella S, Achanta PK, Kandukuri KK, Subramanian R, Benade V, Palacharla RC, Jayarajan P, Pandey S, Jasti V.

J Med Chem. 2019 Feb 14;62(3):1203-1217. doi: 10.1021/acs.jmedchem.8b01280. Epub 2019 Jan 25.

PMID:
30629436
8.

Using the human blood index to investigate host biting plasticity: a systematic review and meta-regression of the three major African malaria vectors.

Orsborne J, Furuya-Kanamori L, Jeffries CL, Kristan M, Mohammed AR, Afrane YA, O'Reilly K, Massad E, Drakeley C, Walker T, Yakob L.

Malar J. 2018 Dec 18;17(1):479. doi: 10.1186/s12936-018-2632-7.

9.

Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa.

Jeffries CL, Lawrence GG, Golovko G, Kristan M, Orsborne J, Spence K, Hurn E, Bandibabone J, Tantely LM, Raharimalala FN, Keita K, Camara D, Barry Y, Wat'senga F, Manzambi EZ, Afrane YA, Mohammed AR, Abeku TA, Hedge S, Khanipov K, Pimenova M, Fofanov Y, Boyer S, Irish SR, Hughes GL, Walker T.

Version 2. Wellcome Open Res. 2018 Nov 27 [revised 2018 Jan 1];3:113. doi: 10.12688/wellcomeopenres.14765.2. eCollection 2018.

10.

Quality by Design (QbD) based process optimisation to develop functionalised particles with modified release properties using novel dry particle coating technique.

Dahmash EZ, Al-Khattawi A, Iyire A, Al-Yami H, Dennison TJ, Mohammed AR.

PLoS One. 2018 Nov 1;13(11):e0206651. doi: 10.1371/journal.pone.0206651. eCollection 2018.

11.

Assessment of sigma-1 receptor occupancy in mice with non-radiolabelled FTC-146 as a tracer.

Bhyrapuneni G, Thentu JB, Mohammed AR, Aleti RR, Padala NP, Ajjala DR, Nirogi R.

J Recept Signal Transduct Res. 2018 Aug;38(4):290-298. doi: 10.1080/10799893.2018.1478855. Epub 2018 Jun 18.

PMID:
29912606
12.

Synthesis, Structure-Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT4 Receptor Partial Agonists.

Nirogi R, Mohammed AR, Shinde AK, Gagginapally SR, Kancharla DM, Middekadi VR, Bogaraju N, Ravella SR, Singh P, Birangal SR, Subramanian R, Palacharla RC, Benade V, Muddana N, Jayarajan P.

J Med Chem. 2018 Jun 14;61(11):4993-5008. doi: 10.1021/acs.jmedchem.8b00457. Epub 2018 May 31.

PMID:
29763304
13.

Current opinions and recommendations of paediatric healthcare professionals - The importance of tablets: Emerging orally disintegrating versus traditional tablets.

Alyami H, Koner J, Huynh C, Terry D, Mohammed AR.

PLoS One. 2018 Feb 28;13(2):e0193292. doi: 10.1371/journal.pone.0193292. eCollection 2018.

14.

Dosage form preference consultation study in children and young adults: paving the way for patient-centred and patient-informed dosage form development.

Alyami H, Dahmash E, Alyami F, Dahmash D, Huynh C, Terry D, Mohammed AR.

Eur J Hosp Pharm. 2017 Nov;24(6):332-337. doi: 10.1136/ejhpharm-2016-001023. Epub 2016 Sep 2.

15.

Colonic delivery of indometacin loaded PGA-co-PDL microparticles coated with Eudragit L100-55 from fast disintegrating tablets.

Tawfeek HM, Abdellatif AAH, Dennison TJ, Mohammed AR, Sadiq Y, Saleem IY.

Int J Pharm. 2017 Oct 5;531(1):80-89. doi: 10.1016/j.ijpharm.2017.08.069. Epub 2017 Aug 15.

PMID:
28818458
16.

Understanding the compaction behaviour of low-substituted HPC: macro, micro, and nano-metric evaluations.

ElShaer A, Al-Khattawi A, Mohammed AR, Warzecha M, Lamprou DA, Hassanin H.

Pharm Dev Technol. 2018 Jun;23(5):442-453. doi: 10.1080/10837450.2017.1363775. Epub 2017 Aug 18.

17.
18.
19.

Discovery and Development of 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer's Disease.

Nirogi R, Shinde A, Kambhampati RS, Mohammed AR, Saraf SK, Badange RK, Bandyala TR, Bhatta V, Bojja K, Reballi V, Subramanian R, Benade V, Palacharla RC, Bhyrapuneni G, Jayarajan P, Goyal V, Jasti V.

J Med Chem. 2017 Mar 9;60(5):1843-1859. doi: 10.1021/acs.jmedchem.6b01662. Epub 2017 Feb 17.

PMID:
28212021
20.

Corrigendum: Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers.

Iyire A, Alaayedi M, Mohammed AR.

Sci Rep. 2016 Oct 14;6:34883. doi: 10.1038/srep34883. No abstract available.

21.

Microparticle surface layering through dry coating: impact of moisture content and process parameters on the properties of orally disintegrating tablets.

Alyami H, Koner J, Dahmash EZ, Bowen J, Terry D, Mohammed AR.

J Pharm Pharmacol. 2017 Jul;69(7):807-822. doi: 10.1111/jphp.12623. Epub 2016 Oct 2.

PMID:
27696423
22.
23.

Design of Experiments to Study the Impact of Process Parameters on Droplet Size and Development of Non-Invasive Imaging Techniques in Tablet Coating.

Dennison TJ, Smith J, Hofmann MP, Bland CE, Badhan RK, Al-Khattawi A, Mohammed AR.

PLoS One. 2016 Aug 22;11(8):e0157267. doi: 10.1371/journal.pone.0157267. eCollection 2016.

24.

Benzamide derivatives and their constrained analogs as histamine H3 receptor antagonists.

Nirogi R, Shinde A, Tiriveedhi V, Kota L, Saraf SK, Badange RK, Mohammed AR, Subramanian R, Muddana N, Bhyrapuneni G, Abraham R.

Eur J Med Chem. 2016 Jan 27;108:655-662. doi: 10.1016/j.ejmech.2015.12.005. Epub 2015 Dec 10.

PMID:
26731168
25.

Characterisation and surface-profiling techniques for composite particles produced by dry powder coating in pharmaceutical drug delivery.

Dahmash EZ, Mohammed AR.

Drug Discov Today. 2016 Apr;21(4):550-61. doi: 10.1016/j.drudis.2015.11.013. Epub 2015 Dec 9. Review.

PMID:
26689131
26.

A Holistic Multi Evidence Approach to Study the Fragmentation Behaviour of Crystalline Mannitol.

Koner JS, Rajabi-Siahboomi A, Bowen J, Perrie Y, Kirby D, Mohammed AR.

Sci Rep. 2015 Nov 10;5:16352. doi: 10.1038/srep16352.

27.

Synthesis and SAR of Imidazo[1,5-a]pyridine derivatives as 5-HT4 receptor partial agonists for the treatment of cognitive disorders associated with Alzheimer's disease.

Nirogi R, Mohammed AR, Shinde AK, Bogaraju N, Gagginapalli SR, Ravella SR, Kota L, Bhyrapuneni G, Muddana NR, Benade V, Palacharla RC, Jayarajan P, Subramanian R, Goyal VK.

Eur J Med Chem. 2015 Oct 20;103:289-301. doi: 10.1016/j.ejmech.2015.08.051. Epub 2015 Sep 1.

PMID:
26363507
28.

Functionalised particles using dry powder coating in pharmaceutical drug delivery: promises and challenges.

Dahmash EZ, Mohammed AR.

Expert Opin Drug Deliv. 2015;12(12):1867-79. doi: 10.1517/17425247.2015.1071351. Epub 2015 Aug 7. Review.

PMID:
26289674
29.

A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets.

ElShaer A, Kaialy W, Akhtar N, Iyire A, Hussain T, Alany R, Mohammed AR.

Eur J Pharm Biopharm. 2015 Oct;96:272-81. doi: 10.1016/j.ejpb.2015.07.028. Epub 2015 Aug 5.

PMID:
26255158
30.

A pragmatic approach for engineering porous mannitol and mechanistic evaluation of particle performance.

Al-Khattawi A, Koner J, Rue P, Kirby D, Perrie Y, Rajabi-Siahboomi A, Mohammed AR.

Eur J Pharm Biopharm. 2015 Aug;94:1-10. doi: 10.1016/j.ejpb.2015.04.011. Epub 2015 May 7.

31.

Paediatric drug development of ramipril: reformulation, in vitro and in vivo evaluation.

Russell C, Begum S, Hussain Y, Hussain M, Huen D, Rahman AS, Perrie Y, Mohammed AR.

J Drug Target. 2015;23(9):854-63. doi: 10.3109/1061186X.2015.1036275. Epub 2015 May 7.

32.

Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction.

Nirogi R, Palacharla RC, Mohammed AR, Manoharan A, Ponnamaneni RK, Bhyrapuneni G.

Chem Biol Interact. 2015 Mar 25;230:9-20. doi: 10.1016/j.cbi.2015.01.028. Epub 2015 Feb 3.

PMID:
25656918
33.

Challenges and emerging solutions in the development of compressed orally disintegrating tablets.

Al-Khattawi A, Mohammed AR.

Expert Opin Drug Discov. 2014 Oct;9(10):1109-20. doi: 10.1517/17460441.2014.941802. Epub 2014 Jul 21. Review.

PMID:
25045997
34.

Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets.

Al-Khattawi A, Alyami H, Townsend B, Ma X, Mohammed AR.

PLoS One. 2014 Jul 15;9(7):e101369. doi: 10.1371/journal.pone.0101369. eCollection 2014.

35.

A novel concentration dependent amino acid ion pair strategy to mediate drug permeation using indomethacin as a model insoluble drug.

ElShaer A, Hanson P, Mohammed AR.

Eur J Pharm Sci. 2014 Oct 1;62:124-31. doi: 10.1016/j.ejps.2014.05.022. Epub 2014 Jun 4.

PMID:
24907680
36.

Systematic screening of compressed ODT excipients: cellulosic versus non-cellulosic.

Al-Khattawi A, Iyire A, Dennison T, Dahmash E, Bailey CJ, Smith J, Rue P, Mohammed AR.

Curr Drug Deliv. 2014;11(4):486-500.

PMID:
24655059
37.

Application of genomics, proteomics and metabolomics in drug discovery, development and clinic.

Russell C, Rahman A, Mohammed AR.

Ther Deliv. 2013 Mar;4(3):395-413. doi: 10.4155/tde.13.4. Review.

PMID:
23442083
38.

Compressed orally disintegrating tablets: excipients evolution and formulation strategies.

Al-khattawi A, Mohammed AR.

Expert Opin Drug Deliv. 2013 May;10(5):651-63. doi: 10.1517/17425247.2013.769955. Epub 2013 Feb 7. Review.

PMID:
23387409
39.

A systematic and mechanistic evaluation of aspartic acid as filler for directly compressed tablets containing trimethoprim and trimethoprim aspartate.

ElShaer A, Hanson P, Mohammed AR.

Eur J Pharm Biopharm. 2013 Apr;83(3):468-76. doi: 10.1016/j.ejpb.2012.11.010. Epub 2012 Dec 1.

PMID:
23207325
40.

Dry powder inhalation of macromolecules using novel PEG-co-polyester microparticle carriers.

Tawfeek HM, Evans AR, Iftikhar A, Mohammed AR, Shabir A, Somavarapu S, Hutcheon GA, Saleem IY.

Int J Pharm. 2013 Jan 30;441(1-2):611-9. doi: 10.1016/j.ijpharm.2012.10.036. Epub 2012 Nov 1.

PMID:
23124106
41.

The role of lipid geometry in designing liposomes for the solubilisation of poorly water soluble drugs.

Ali MH, Moghaddam B, Kirby DJ, Mohammed AR, Perrie Y.

Int J Pharm. 2013 Aug 30;453(1):225-32. doi: 10.1016/j.ijpharm.2012.06.056. Epub 2012 Jul 3.

PMID:
22766442
42.

Dissolution rate enhancement, in vitro evaluation and investigation of drug release kinetics of chloramphenicol and sulphamethoxazole solid dispersions.

Khan S, Batchelor H, Hanson P, Saleem IY, Perrie Y, Mohammed AR.

Drug Dev Ind Pharm. 2013 May;39(5):704-15. doi: 10.3109/03639045.2012.689763. Epub 2012 May 29.

PMID:
22639985
43.

The impact of ageing on the barriers to drug delivery.

Perrie Y, Badhan RK, Kirby DJ, Lowry D, Mohammed AR, Ouyang D.

J Control Release. 2012 Jul 20;161(2):389-98. doi: 10.1016/j.jconrel.2012.01.020. Epub 2012 Jan 24. Review.

PMID:
22289435
44.

Trigger release liposome systems: local and remote controlled delivery?

Bibi S, Lattmann E, Mohammed AR, Perrie Y.

J Microencapsul. 2012;29(3):262-76. doi: 10.3109/02652048.2011.646330. Epub 2011 Dec 30.

PMID:
22208705
45.

Preparation and characterization of amino acids-based trimethoprim salts.

Elshaer A, Hanson P, Worthington T, Lambert P, Mohammed AR.

Pharmaceutics. 2012 Feb 16;4(1):179-96. doi: 10.3390/pharmaceutics4010179.

46.

Formulation of multiparticulate systems as lyophilised orally disintegrating tablets.

Alhusban F, Perrie Y, Mohammed AR.

Eur J Pharm Biopharm. 2011 Nov;79(3):627-34. doi: 10.1016/j.ejpb.2011.05.014. Epub 2011 Jun 13.

PMID:
21693189
47.

Physicochemical characterisation, drug polymer dissolution and in vitro evaluation of phenacetin and phenylbutazone solid dispersions with polyethylene glycol 8000.

Khan S, Batchelor H, Hanson P, Perrie Y, Mohammed AR.

J Pharm Sci. 2011 Oct;100(10):4281-94. doi: 10.1002/jps.22613. Epub 2011 May 10.

PMID:
21560130
48.

Use of amino acids as counterions improves the solubility of the BCS II model drug, indomethacin.

ElShaer A, Khan S, Perumal D, Hanson P, Mohammed AR.

Curr Drug Deliv. 2011 Jul;8(4):363-72.

PMID:
21453261
49.

Effects of ball-milling on PLGA polymer and its implication on lansoprazole-loaded nanoparticles.

Shabir A, Alhusban F, Perrie Y, Mohammed AR.

J Basic Clin Pharm. 2011 Mar;2(2):71-82. Epub 2011 May 15.

50.

The application of monolayer studies in the understanding of liposomal formulations.

Moghaddam B, Ali MH, Wilkhu J, Kirby DJ, Mohammed AR, Zheng Q, Perrie Y.

Int J Pharm. 2011 Sep 30;417(1-2):235-44. doi: 10.1016/j.ijpharm.2011.01.020. Epub 2011 Jan 18. Review.

PMID:
21251964

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