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Role of AKT and mTOR Signaling Pathways in the Induction of Epithelial-Mesenchymal Transition (EMT) Process.

Roshan MK, Soltani A, Soleimani A, Kahkhaie KR, Afshari AR, Soukhtanloo M.

Biochimie. 2019 Aug 8. pii: S0300-9084(19)30235-4. doi: 10.1016/j.biochi.2019.08.003. [Epub ahead of print] Review.


Zataria multiflora and its main ingredient, carvacrol, affect on the renal function, histopathological, biochemical and antioxidant parameters in adriamycin-induced nephrotic rats.

Mohebbati R, Jalili-Nik M, Saghi H, Sadatfaraji H, Soukhtanloo M.

Arch Physiol Biochem. 2019 Aug 9:1-9. doi: 10.1080/13813455.2019.1650069. [Epub ahead of print]


Cytotoxic effects of auraptene against a human malignant glioblastoma cell line.

Afshari AR, Karimi Roshan M, Soukhtanloo M, Ghorbani A, Rahmani F, Jalili-Nik M, Vahedi MM, Hoseini A, Sadeghnia HR, Mollazadeh H, Mousavi SH.

Avicenna J Phytomed. 2019 Jul-Aug;9(4):334-346.


Acute and sub-acute toxicity evaluation of the root extract of Rheum turkestanicum Janisch.

Jahani Yazdi A, Javanshir S, Soukhtanloo M, Jalili-Nik M, Jafarian AH, Iranshahi M, Hasanpour M, Khatami SM, Hosseini A, Amiri MS, Ghorbani A.

Drug Chem Toxicol. 2019 Jul 2:1-7. doi: 10.1080/01480545.2018.1561713. [Epub ahead of print]


Effects of PPAR-γ agonist, pioglitazone on brain tissues oxidative damage and learning and memory impairment in juvenile hypothyroid rats.

Baghcheghi Y, Salmani H, Beheshti F, Shafei MN, Sadeghnia HR, Soukhtanloo M, Ebrahimzadeh Bideskan A, Hosseini M.

Int J Neurosci. 2019 Oct;129(10):1024-1038. doi: 10.1080/00207454.2019.1632843. Epub 2019 Jul 3.


Thymoquinone alleviates renal interstitial fibrosis and kidney dysfunction in rats with unilateral ureteral obstruction.

Hosseinian S, Shahraki S, Ebrahimzadeh Bideskan A, Shafei MN, Sadeghnia HR, Soukhtanloo M, Rahmani F, Khajavi Rad A.

Phytother Res. 2019 Aug;33(8):2023-2033. doi: 10.1002/ptr.6376. Epub 2019 Jun 18.


Overexpression of Lactate Dehydrogenase in the Saliva and Tissues of Patients with Head and Neck Squamous Cell Carcinoma.

Mohajertehran F, Ayatollahi H, Jafarian AH, Khazaeni K, Soukhtanloo M, Shakeri MT, Mohtasham N.

Rep Biochem Mol Biol. 2019 Jan;7(2):142-149.


PPAR-γ: Its ligand and its regulation by microRNAs.

Seiri P, Abi A, Soukhtanloo M.

J Cell Biochem. 2019 Feb 15. doi: 10.1002/jcb.28419. [Epub ahead of print]


Effects of standardized Zataria multiflora extract and its major ingredient, Carvacrol, on Adriamycin-induced hepatotoxicity in rat.

Mohebbati R, Paseban M, Soukhtanloo M, Jalili-Nik M, Shafei MN, Yazdi AJ, Rad AK.

Biomed J. 2018 Dec;41(6):340-347. doi: 10.1016/ Epub 2019 Jan 11.


CD73; a key ectonucleotidase in the development of breast cancer: Recent advances and perspectives.

Soleimani A, Taghizadeh E, Shahsavari S, Amini Y, Rashidpour H, Azadian E, Jafari A, Parizadeh MR, Mashayekhi K, Soukhtanloo M, Jaafari MR.

J Cell Physiol. 2019 Jan 28. doi: 10.1002/jcp.28187. [Epub ahead of print] Review.


Teucrium polium L. Improves Blood Glucose and Lipids and Ameliorates Oxidative Stress in Heart and Aorta of Diabetic Rats.

Zabihi NA, Mousavi SM, Mahmoudabady M, Soukhtanloo M, Sohrabi F, Niazmand S.

Int J Prev Med. 2018 Dec 24;9:110. doi: 10.4103/ijpvm.IJPVM_189_17. eCollection 2018.


The Preventive Effects of Standardized Extract of Zataria multiflora and Carvacrol on Acetaminophen-Induced Hepatotoxicity in Rat: - Zataria multiflora and Carvacrol and Hepatotoxicity.

Mohebbati R, Paseban M, Beheshti F, Soukhtanloo M, Shafei MN, Rakhshandeh H, Rad AK.

J Pharmacopuncture. 2018 Dec;21(4):249-257. doi: 10.3831/KPI.2018.21.028. Epub 2018 Dec 31.


Safranal Attenuates Excitotoxin-Induced Oxidative OLN-93 Cells Injury.

Alavi MS, Fanoudi S, Fard AV, Soukhtanloo M, Hosseini M, Barzegar H, Sadeghnia HR.

Drug Res (Stuttg). 2019 Jun;69(6):323-329. doi: 10.1055/a-0790-8200. Epub 2018 Nov 21.


Plantago major protects against cisplatin-induced renal dysfunction and tissue damage in rats.

Parhizgar S, Hosseinian S, Soukhtanloo M, Bideskan AE, Hadjzadeh MA, Shahraki S, Noshahr ZS, Heravi NE, Haghshenas M, Rad AK.

Saudi J Kidney Dis Transpl. 2018 Sep-Oct;29(5):1057-1064. doi: 10.4103/1319-2442.243960.


Therapeutic potency of pharmacological adenosine receptors agonist/antagonist on cancer cell apoptosis in tumor microenvironment, current status, and perspectives.

Soleimani A, Bahreyni A, Roshan MK, Soltani A, Ryzhikov M, Shafiee M, Soukhtanloo M, Jaafari MR, Mashkani B, Hassanian SM.

J Cell Physiol. 2019 Mar;234(3):2329-2336. doi: 10.1002/jcp.27249. Epub 2018 Sep 7. Review.


Administration of Nigella sativa during neonatal and juvenile growth period improved liver function of propylthiouracil-induced hypothyroid rats.

Hosseini M, Ghasemi S, Hadjzadeh MAR, Ghorbani A, Aghili S, Aghaei A, Soukhtanloo M, Beheshti F.

J Matern Fetal Neonatal Med. 2018 Sep 6:1-8. doi: 10.1080/14767058.2018.1500540. [Epub ahead of print]


Nigella sativa extract is a potent therapeutic agent for renal inflammation, apoptosis, and oxidative stress in a rat model of unilateral ureteral obstruction.

Hosseinian S, Ebrahimzadeh Bideskan A, Shafei MN, Sadeghnia HR, Soukhtanloo M, Shahraki S, Samadi Noshahr Z, Khajavi Rad A.

Phytother Res. 2018 Nov;32(11):2290-2298. doi: 10.1002/ptr.6169. Epub 2018 Aug 2.


In vivo and In vitro effects of ethanolic extract of Trigonella foenum-graecum L. seeds on proliferation, angiogenesis and tube formation of endothelial cells.

Iranmanesh M, Mohebbati R, Forouzanfar F, Roshan MK, Ghorbani A, Nik MJ, Soukhtanloo M.

Res Pharm Sci. 2018 Aug;13(4):343-352. doi: 10.4103/1735-5362.235161.


Nigella sativa prevented liver and renal tissue damage in lipopolysaccharide-treated rats.

Beheshti F, Norouzi F, Abareshi A, Khazaei M, Alikhani V, Moussavi S, Biglari G, Soukhtanloo M, Hosseini M.

Saudi J Kidney Dis Transpl. 2018 May-Jun;29(3):554-566. doi: 10.4103/1319-2442.235184.


The Status of Nitric Oxide and its Backup, Heme Oxygenase 1, in Thromboangiitis Obliterans.

Aliee A, Zahedi Avval F, Taheri H, Moghadam SM, Soukhtanloo M, Hamidi Alamdari D, Fazeli B.

Rep Biochem Mol Biol. 2018 Apr;6(2):197-202.


Angiotensin receptor blocker, losartan ameliorates neuroinflammation and behavioral consequences of lipopolysaccharide injection.

Salmani H, Hosseini M, Beheshti F, Baghcheghi Y, Sadeghnia HR, Soukhtanloo M, Shafei MN, Khazaei M.

Life Sci. 2018 Jun 15;203:161-170. doi: 10.1016/j.lfs.2018.04.033. Epub 2018 Apr 22.


Memory enhancing effect of Nigella Sativa hydro-alcoholic extract on lipopolysaccharide-induced memory impairment in rats.

Norouzi F, Hosseini M, Abareshi A, Beheshti F, Khazaei M, Shafei MN, Soukhtanloo M, Gholamnezhad Z, Anaeigoudari A.

Drug Chem Toxicol. 2019 May;42(3):270-279. doi: 10.1080/01480545.2018.1447578. Epub 2018 Mar 28.


Salix alba attenuated oxidative stress in the heart and kidney of hypercholesterolemic rabbits.

Amel Zabihi N, Mahmoudabady M, Soukhtanloo M, Hayatdavoudi P, Beheshti F, Niazmand S.

Avicenna J Phytomed. 2018 Jan-Feb;8(1):63-72.


The effects of vitamin E on brain derived neurotrophic factor, tissues oxidative damage and learning and memory of juvenile hypothyroid rats.

Baghcheghi Y, Beheshti F, Shafei MN, Salmani H, Sadeghnia HR, Soukhtanloo M, Anaeigoudari A, Hosseini M.

Metab Brain Dis. 2018 Jun;33(3):713-724. doi: 10.1007/s11011-017-0176-0. Epub 2017 Dec 30.


Mixed hydroalcoholic extracts of Nigella sativa and Curcuma longa improves adriamycin-induced renal injury in rat.

Mohebbati R, Shafei MN, Beheshti F, Soukhtanloo M, Roshan NM, Anaeigoudari A, Parhizgar S, Hosseinian S, Khazdeir MR, Rad AK.

Saudi J Kidney Dis Transpl. 2017 Nov-Dec;28(6):1270-1281. doi: 10.4103/1319-2442.220880.


Alterations in Lipid Profile, Zinc and Copper Levels and Superoxide Dismutase Activities in Normal Pregnancy and Preeclampsia.

Keshavarz P, Nobakht M Gh BF, Mirhafez SR, Nematy M, Azimi-Nezhad M, Afin SA, Esmaily H, Pourali L, Hakak AM, Soukhtanloo M, Mirteimouri M, Ghomian N, Ferns GA.

Am J Med Sci. 2017 Jun;353(6):552-558. doi: 10.1016/j.amjms.2017.03.022. Epub 2017 Mar 16.


Protective effect against brain tissues oxidative damage as a possible mechanism for beneficial effects of L-arginine on lipopolysaccharide induced memory impairment in rats.

Hosseini M, Anaeigoudari A, Beheshti F, Soukhtanloo M, Nosratabadi R.

Drug Chem Toxicol. 2018 Apr;41(2):175-181. doi: 10.1080/01480545.2017.1336173. Epub 2017 Jun 22.


Thymoquinone ameliorates renal damage in unilateral ureteral obstruction in rats.

Hosseinian S, Rad AK, Bideskan AE, Soukhtanloo M, Sadeghnia H, Shafei MN, Motejadded F, Mohebbati R, Shahraki S, Beheshti F.

Pharmacol Rep. 2017 Aug;69(4):648-657. doi: 10.1016/j.pharep.2017.03.002. Epub 2017 Mar 14.


Protective Effect of PPARγ Agonists on Cerebellar Tissues Oxidative Damage in Hypothyroid Rats.

Baghcheghi Y, Beheshti F, Salmani H, Soukhtanloo M, Hosseini M.

Neurol Res Int. 2016;2016:1952561. doi: 10.1155/2016/1952561. Epub 2016 Dec 26.


Protection against brain tissues oxidative damage as a possible mechanism for improving effects of low doses of estradiol on scopolamine-induced learning and memory impairments in ovariectomized rats.

Hejazian SH, Karimi S, Hosseini M, Mousavi SM, Soukhtanloo M.

Adv Biomed Res. 2016 Jul 29;5:123. doi: 10.4103/2277-9175.186981. eCollection 2016.


Renoprotective Effect of Plantago Major Against Nephrotoxicity and Oxidative Stress Induced by Cisplatin.

Parhizgar S, Hosseinian S, Hadjzadeh MA, Soukhtanloo M, Ebrahimzadeh A, Mohebbati R, Naji Ebrahimi Yazd Z, Khajavi Rad A.

Iran J Kidney Dis. 2016 Jul;10(4):182-8.


Beneficial effects of garlic on learning and memory deficits and brain tissue damages induced by lead exposure during juvenile rat growth is comparable to the effect of ascorbic acid.

Ghasemi S, Hosseini M, Feizpour A, Alipour F, Sadeghi A, Vafaee F, Mohammadpour T, Soukhtanloo M, Ebrahimzadeh Bideskan A, Beheshti F.

Drug Chem Toxicol. 2017 Apr;40(2):206-214. doi: 10.1080/01480545.2016.1197238. Epub 2016 Jul 7.


Inducible nitric oxide inhibitor aminoguanidine, ameliorates deleterious effects of lipopolysaccharide on memory and long term potentiation in rat.

Anaeigoudari A, Soukhtanloo M, Reisi P, Beheshti F, Hosseini M.

Life Sci. 2016 Aug 1;158:22-30. doi: 10.1016/j.lfs.2016.06.019. Epub 2016 Jun 21.


Adriamycin-induced oxidative stress is prevented by mixed hydro-alcoholic extract of Nigella sativa and Curcuma longa in rat kidney.

Mohebbati R, Shafei MN, Soukhtanloo M, Mohammadian Roshan N, Khajavi Rad A, Anaeigoudari A, Hosseinian S, Karimi S, Beheshti F.

Avicenna J Phytomed. 2016 Jan-Feb;6(1):86-94.


Nigella sativa seed decreases endothelial dysfunction in streptozotocin-induced diabetic rat aorta.

Abbasnezhad A, Niazmand S, Mahmoudabady M, Soukhtanloo M, Rezaee SA, Mousavi SM.

Avicenna J Phytomed. 2016 Jan-Feb;6(1):67-76.


Feeding of Nigella sativa during neonatal and juvenile growth improves learning and memory of rats.

Beheshti F, Hosseini M, Vafaee F, Shafei MN, Soukhtanloo M.

J Tradit Complement Med. 2015 Jan 17;6(2):146-52. doi: 10.1016/j.jtcme.2014.11.039. eCollection 2016 Apr.


Effect of exogenous leptin on serum levels of lipids, glucose, renal and hepatic variables in both genders of obese and streptozotocin-induced diabetic rats.

Hayatdavoudi P, Ghasemi M, Zendehbad B, Soukhtanloo M, Golshan A, Hadjzadeh MA.

Iran J Basic Med Sci. 2015 Nov;18(11):1072-8.


Neuronal nitric oxide synthase has a role in the detrimental effects of lipopolysaccharide on spatial memory and synaptic plasticity in rats.

Anaeigoudari A, Soukhtanloo M, Shafei MN, Sadeghnia HR, Reisi P, Beheshti F, Behradnia S, Mousavi SM, Hosseini M.

Pharmacol Rep. 2016 Apr;68(2):243-9. doi: 10.1016/j.pharep.2015.09.004. Epub 2015 Sep 26.


Toxicity evaluation of hydroalcoholic extract of Ferula gummosa root.

Ghorbani A, Mohebbati R, Jafarian AH, Vahedi MM, Hosseini SM, Soukhtanloo M, Sadeghnia HR, Azar Hosseini.

Regul Toxicol Pharmacol. 2016 Jun;77:35-41. doi: 10.1016/j.yrtph.2016.02.008. Epub 2016 Feb 15.


The effects of L-arginine on spatial memory and synaptic plasticity impairments induced by lipopolysaccharide.

Anaeigoudari A, Shafei MN, Soukhtanloo M, Sadeghnia HR, Reisi P, Nosratabadi R, Behradnia S, Hosseini M.

Adv Biomed Res. 2015 Sep 28;4:202. doi: 10.4103/2277-9175.166138. eCollection 2015.


The effect of angiotensin-converting enzyme inhibition on inflammatory and angiogenic factors in hypercholesterolemia.

Mahmoudabady M, Kazemi N, Niazmand S, Rezaee SA, Soukhtanloo M, Hosseini M.

Pharmacol Rep. 2015 Oct;67(5):837-41. doi: 10.1016/j.pharep.2015.01.008. Epub 2015 Jan 22.


Lipopolysaccharide-induced memory impairment in rats is preventable using 7-nitroindazole.

Anaeigoudari A, Shafei MN, Soukhtanloo M, Sadeghnia HR, Reisi P, Beheshti F, Mohebbati R, Mousavi SM, Hosseini M.

Arq Neuropsiquiatr. 2015 Sep;73(9):784-90. doi: 10.1590/0004-282X20150121.


The effect of hydro-alcoholic extract of Artemisia absinthium on appetite in male rats.

Baghban Taraghdari S, Nematy M, Mazidi M, Kamgar M, Soukhtanloo M, Hosseini M, Rakhshandeh H, Norouzy A, Esmaily H.

Avicenna J Phytomed. 2015 Mar-Apr;5(2):78-83.


The effect of carvacrol on systemic inflammation in guinea pigs model of COPD induced by cigarette smoke exposure.

Mahtaj LG, Feizpour A, Kianmehr M, Soukhtanloo M, Boskabady MH.

Pharmacol Rep. 2015 Feb;67(1):140-5. doi: 10.1016/j.pharep.2014.08.017. Epub 2014 Aug 29.


The effects of tamoxifen on learning, memory and brain tissues oxidative damage in ovariectomized and naïve female rats.

Zabihi H, Hosseini M, Pourganji M, Oryan S, Soukhtanloo M, Niazmand S.

Adv Biomed Res. 2014 Oct 21;3:219. doi: 10.4103/2277-9175.143297. eCollection 2014.


The effect of hydroalcoholic extract of Cannabis Sativa on appetite hormone in rat.

Mazidi M, Baghban Taraghdari S, Rezaee P, Kamgar M, Jomezadeh MR, Akbarieh Hasani O, Soukhtanloo M, Hosseini M, Gholamnezhad Z, Rakhshandeh H, Norouzy A, Esmaily H, Patterson M, Nematy M.

J Complement Integr Med. 2014 Dec;11(4):253-7. doi: 10.1515/jcim-2014-0006.


Effects of melatonin on biochemical factors and food and water consumption in diabetic rats.

Bibak B, Khalili M, Rajaei Z, Soukhtanloo M, Hadjzadeh MA, Hayatdavoudi P.

Adv Biomed Res. 2014 Aug 19;3:173. doi: 10.4103/2277-9175.139191. eCollection 2014.


The effects of soy extract on spatial learning and memory damage induced by global ischemia in ovariectomised rats.

Vafaee F, Hosseini M, Sadeghinia HR, Hadjzadeh MA, Soukhtanloo M, Rahimi M.

Malays J Med Sci. 2014 May;21(3):19-30.

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