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Items: 1 to 50 of 62

1.

Oncogenic Akt-FOXO3 loop favors tumor-promoting modes and enhances oxidative damage-associated hepatocellular carcinogenesis.

Lu M, Hartmann D, Braren R, Gupta A, Wang B, Wang Y, Mogler C, Cheng Z, Wirth T, Friess H, Kleeff J, Hüser N, Sunami Y.

BMC Cancer. 2019 Sep 5;19(1):887. doi: 10.1186/s12885-019-6110-6.

2.

Caspase-8 modulates physiological and pathological angiogenesis during retina development.

Tisch N, Freire-Valls A, Yerbes R, Paredes I, La Porta S, Wang X, Martín-Pérez R, Castro L, Wong WW, Coultas L, Strilic B, Gröne HJ, Hielscher T, Mogler C, Adams R, Heiduschka P, Claesson-Welsh L, Mazzone M, López-Rivas A, Schmidt T, Augustin HG, Ruiz de Almodovar C.

J Clin Invest. 2019 Aug 27. pii: 122767. doi: 10.1172/JCI122767. [Epub ahead of print]

3.

Molecular characterization of hepatic epithelioid hemangioendothelioma reveals alterations in various genes involved in DNA repair, epigenetic regulation, signaling pathways, and cell cycle control.

Mogler C, Koschny R, Heilig CE, Frohling S, Schirmacher P, Weichert W, Pfarr N.

Genes Chromosomes Cancer. 2019 Aug 7. doi: 10.1002/gcc.22795. [Epub ahead of print]

PMID:
31390105
4.

Progression after Immunotherapy for Fibrolamellar Carcinoma.

Bauer U, Mogler C, Braren RF, Algül H, Schmid RM, Ehmer U.

Visc Med. 2019 Mar;35(1):39-42. doi: 10.1159/000497464. Epub 2019 Feb 12.

PMID:
31312648
5.

Brg1 promotes liver regeneration after partial hepatectomy via regulation of cell cycle.

Wang B, Kaufmann B, Engleitner T, Lu M, Mogler C, Olsavszky V, Öllinger R, Zhong S, Geraud C, Cheng Z, Rad RR, Schmid RM, Friess H, Hüser N, Hartmann D, von Figura G.

Sci Rep. 2019 Feb 20;9(1):2320. doi: 10.1038/s41598-019-38568-w.

6.

BRAF V600E and Retinoic Acid in Radioiodine-Refractory Papillary Thyroid Cancer.

Groener JB, Gelen D, Mogler C, Herpel E, Toth C, Kender Z, Peichl M, Haufe S, Haberkorn U, Sulaj A, Zemva J, Kopf S, Nawroth PP, Brune M, Rudofsky G.

Horm Metab Res. 2019 Jan;51(1):69-75. doi: 10.1055/a-0765-9078. Epub 2018 Nov 5.

PMID:
30396219
7.

[Histopathological research laboratories in translational research : Conception and integration into the infrastructure of pathological institutes].

Steiger K, Ballke S, Yen HY, Seelbach O, Alkhamas A, Boxberg M, Schwamborn K, Knolle PA, Weichert W, Mogler C.

Pathologe. 2019 Mar;40(2):172-178. doi: 10.1007/s00292-018-0458-2. German.

PMID:
30027333
8.

Computed tomography and histopathological findings after embolization with inherently radiopaque 40μm-microspheres, standard 40μm-microspheres and iodized oil in a porcine liver model.

Vollherbst DF, Gockner T, Do T, Holzer K, Mogler C, Flechsig P, Harms A, Schlett CL, Pereira PL, Richter GM, Kauczor HU, Sommer CM.

PLoS One. 2018 Jul 9;13(7):e0198911. doi: 10.1371/journal.pone.0198911. eCollection 2018.

9.

GPR182 is a novel marker for sinusoidal endothelial differentiation with distinct GPCR signaling activity in vitro.

Schmid CD, Schledzewski K, Mogler C, Waldburger N, Kalna V, Marx A, Randi AM, Géraud C, Goerdt S, Koch PS.

Biochem Biophys Res Commun. 2018 Feb 26;497(1):32-38. doi: 10.1016/j.bbrc.2018.01.185. Epub 2018 Feb 1.

10.

Neutralization of CD95 ligand protects the liver against ischemia-reperfusion injury and prevents acute liver failure.

Al-Saeedi M, Steinebrunner N, Kudsi H, Halama N, Mogler C, Büchler MW, Krammer PH, Schemmer P, Müller M.

Cell Death Dis. 2018 Jan 26;9(2):132. doi: 10.1038/s41419-017-0150-0.

11.

Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis.

La Porta S, Roth L, Singhal M, Mogler C, Spegg C, Schieb B, Qu X, Adams RH, Baldwin HS, Savant S, Augustin HG.

J Clin Invest. 2018 Feb 1;128(2):834-845. doi: 10.1172/JCI94674. Epub 2018 Jan 22.

12.

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart.

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, Schmid RM, Adams RH, Gröne HJ, Hell R, Okun JG, Backs J, Nawroth PP, Herzig S, Fischer A.

Circulation. 2018 Jun 12;137(24):2592-2608. doi: 10.1161/CIRCULATIONAHA.117.029733. Epub 2018 Jan 20.

PMID:
29353241
13.

[Spindle-cell osteosclerotic bone lesion with MDM2 amplification].

Mogler C, Boxberg M, Knebel C, Weichert W, Wörtler K, Specht K.

Pathologe. 2018 Mar;39(2):186-190. doi: 10.1007/s00292-017-0394-6. German.

PMID:
29209796
14.

Epithelioid sarcoma of the plantar fascia mimicking Morbus Ledderhose - A severe pitfall for clinical and histopathological misinterpretation.

Toepfer A, Harrasser N, Dreyer F, Mogler C, Walther M, von Eisenhart-Rothe R.

Foot Ankle Surg. 2017 Dec;23(4):e25-e30. doi: 10.1016/j.fas.2017.03.013. Epub 2017 Apr 5.

PMID:
29202999
15.

Mammary analogue secretory carcinoma of salivary glands: diagnostic pitfall with distinct immunohistochemical profile and molecular features.

Bissinger O, Götz C, Kolk A, Bier HA, Agaimy A, Frenzel H, Perner S, Ribbat-Idel J, Wolff KD, Weichert W, Mogler C.

Rare Tumors. 2017 Oct 3;9(3):7162. doi: 10.4081/rt.2017.7162. eCollection 2017 Oct 3.

16.

Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation.

Thomas Koch D, Pickhard A, Gebel L, Buchberger AMS, Bas M, Mogler C, Reiter R, Piontek G, Wirth M.

Oncotarget. 2017 May 16;8(20):32668-32682. doi: 10.18632/oncotarget.15949.

17.

Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin.

Mogler C, König C, Wieland M, Runge A, Besemfelder E, Komljenovic D, Longerich T, Schirmacher P, Augustin HG.

EMBO Mol Med. 2017 Jun;9(6):741-749. doi: 10.15252/emmm.201607222.

18.

BMP-9 interferes with liver regeneration and promotes liver fibrosis.

Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P.

Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23.

PMID:
28336518
19.

Endothelial Notch1 Activity Facilitates Metastasis.

Wieland E, Rodriguez-Vita J, Liebler SS, Mogler C, Moll I, Herberich SE, Espinet E, Herpel E, Menuchin A, Chang-Claude J, Hoffmeister M, Gebhardt C, Brenner H, Trumpp A, Siebel CW, Hecker M, Utikal J, Sprinzak D, Fischer A.

Cancer Cell. 2017 Mar 13;31(3):355-367. doi: 10.1016/j.ccell.2017.01.007. Epub 2017 Feb 23.

20.

Endosialin Promotes Atherosclerosis Through Phenotypic Remodeling of Vascular Smooth Muscle Cells.

Hasanov Z, Ruckdeschel T, König C, Mogler C, Kapel SS, Korn C, Spegg C, Eichwald V, Wieland M, Appak S, Augustin HG.

Arterioscler Thromb Vasc Biol. 2017 Mar;37(3):495-505. doi: 10.1161/ATVBAHA.116.308455. Epub 2017 Jan 26.

PMID:
28126825
21.

Tumour budding activity and cell nest size determine patient outcome in oral squamous cell carcinoma: proposal for an adjusted grading system.

Boxberg M, Jesinghaus M, Dorfner C, Mogler C, Drecoll E, Warth A, Steiger K, Bollwein C, Meyer P, Wolff KD, Kolk A, Weichert W.

Histopathology. 2017 Jun;70(7):1125-1137. doi: 10.1111/his.13173. Epub 2017 Mar 28.

PMID:
28122134
22.

Endosialin-Expressing Pericytes Promote Metastatic Dissemination.

Viski C, König C, Kijewska M, Mogler C, Isacke CM, Augustin HG.

Cancer Res. 2016 Sep 15;76(18):5313-25. doi: 10.1158/0008-5472.CAN-16-0932.

23.

Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis.

Preusch MR, Rusnak J, Staudacher K, Mogler C, Uhlmann L, Sievers P, Bea F, Katus HA, Blessing E, Staudacher I.

Drug Des Devel Ther. 2016 Aug 26;10:2691-9. doi: 10.2147/DDDT.S105718. eCollection 2016.

24.

Long term follow up after resection emphasizes the role of surgery in Primary Hepatic Epithelioid Hemangioendothelioma.

Mehrabi A, Hoffmann K, Weiss KH, Mogler C, Schemmer P, Büchler MW, Alldinger I.

Ann Med Surg (Lond). 2016 Mar 10;11:1-4. doi: 10.1016/j.amsu.2016.03.002. eCollection 2016 Nov.

25.

Electrochemical Effects after Transarterial Chemoembolization in Combination with Percutaneous Irreversible Electroporation: Observations in an Acute Porcine Liver Model.

Vollherbst D, Bertheau RC, Fritz S, Mogler C, Kauczor HU, Ryschich E, Radeleff BA, Pereira PL, Sommer CM.

J Vasc Interv Radiol. 2016 Jun;27(6):913-921.e2. doi: 10.1016/j.jvir.2016.02.001. Epub 2016 Apr 18.

PMID:
27103147
26.

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling.

Scholz B, Korn C, Wojtarowicz J, Mogler C, Augustin I, Boutros M, Niehrs C, Augustin HG.

Dev Cell. 2016 Jan 11;36(1):79-93. doi: 10.1016/j.devcel.2015.12.015.

27.

Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma.

Reuter T, Warta R, Theile D, Meid AD, Rigalli JP, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1141-50. doi: 10.1007/s00210-015-1150-1. Epub 2015 Jul 4.

PMID:
26141049
28.

Fibromuscular dysplasia of the coronary arteries: a rare cause of death in infants and young children.

Mogler C, Springer W, Gorenflo M.

Cardiol Young. 2016 Jan;26(1):202-5. doi: 10.1017/S104795111500061X. Epub 2015 May 14.

PMID:
25971984
29.

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice.

Maass T, Marquardt J, Lee JS, Krupp M, Scholz-Kreisel P, Mogler C, Schirmacher P, Müller M, Westphal H, Galle PR, Teufel A.

Oncotarget. 2016 May 17;7(20):28903-13. doi: 10.18632/oncotarget.3293.

30.

Aggressive primary cutaneous B-cell lymphomas show increased Angiopoietin-2-induced angiogenesis.

Teichert M, Stumpf C, Booken N, Wobser M, Nashan D, Hallermann C, Mogler C, Müller CS, Becker JC, Moritz RK, Andrulis M, Nicolay JP, Goerdt S, Thomas M, Klemke CD, Augustin HG, Felcht M.

Exp Dermatol. 2015 Jun;24(6):424-9. doi: 10.1111/exd.12688. Epub 2015 Apr 16.

PMID:
25776770
31.

Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage.

Mogler C, Wieland M, König C, Hu J, Runge A, Korn C, Besemfelder E, Breitkopf-Heinlein K, Komljenovic D, Dooley S, Schirmacher P, Longerich T, Augustin HG.

EMBO Mol Med. 2015 Mar;7(3):332-8. doi: 10.15252/emmm.201404246.

32.

Hepatobiliary malignancies in Wilson disease.

Pfeiffenberger J, Mogler C, Gotthardt DN, Schulze-Bergkamen H, Litwin T, Reuner U, Hefter H, Huster D, Schemmer P, Członkowska A, Schirmacher P, Stremmel W, Cassiman D, Weiss KH.

Liver Int. 2015 May;35(5):1615-22. doi: 10.1111/liv.12727. Epub 2014 Nov 23.

PMID:
25369181
33.

Association of drug transporter expression with mortality and progression-free survival in stage IV head and neck squamous cell carcinoma.

Warta R, Theile D, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Weiss J, Dyckhoff G.

PLoS One. 2014 Oct 2;9(9):e108908. doi: 10.1371/journal.pone.0108908. eCollection 2014.

34.

Sphere-enhanced microwave ablation (sMWA) versus bland microwave ablation (bMWA): technical parameters, specific CT 3D rendering and histopathology.

Gockner TL, Zelzer S, Mokry T, Gnutzmann D, Bellemann N, Mogler C, Beierfuß A, Köllensperger E, Germann G, Radeleff BA, Stampfl U, Kauczor HU, Pereira PL, Sommer CM.

Cardiovasc Intervent Radiol. 2015 Apr;38(2):442-52. doi: 10.1007/s00270-014-0964-4. Epub 2014 Aug 29.

PMID:
25167958
35.

Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse.

Steinebrunner N, Mogler C, Vittas S, Hoyler B, Sandig C, Stremmel W, Eisenbach C.

BMC Gastroenterol. 2014 Aug 19;14:148. doi: 10.1186/1471-230X-14-148.

36.

An inducible hepatocellular carcinoma model for preclinical evaluation of antiangiogenic therapy in adult mice.

Runge A, Hu J, Wieland M, Bergeest JP, Mogler C, Neumann A, Géraud C, Arnold B, Rohr K, Komljenovic D, Schirmacher P, Goerdt S, Augustin HG.

Cancer Res. 2014 Aug 1;74(15):4157-69. doi: 10.1158/0008-5472.CAN-13-2311. Epub 2014 Jun 6.

37.

Aberrant self-renewal and quiescence contribute to the aggressiveness of glioblastoma.

Campos B, Gal Z, Baader A, Schneider T, Sliwinski C, Gassel K, Bageritz J, Grabe N, von Deimling A, Beckhove P, Mogler C, Goidts V, Unterberg A, Eckstein V, Herold-Mende C.

J Pathol. 2014 Sep;234(1):23-33. doi: 10.1002/path.4366. Epub 2014 Jul 10.

PMID:
24756862
38.

Reduced promoter methylation and increased expression of CSPG4 negatively influences survival of HNSCC patients.

Warta R, Herold-Mende C, Chaisaingmongkol J, Popanda O, Mock A, Mogler C, Osswald F, Herpel E, Küstner S, Eckstein V, Plass C, Plinkert P, Schmezer P, Dyckhoff G.

Int J Cancer. 2014 Dec 1;135(11):2727-34. doi: 10.1002/ijc.28906. Epub 2014 Apr 26.

39.

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.

Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Pappo O, Schweitzer N, Tornillo L, Kanarek N, Quagliata L, Zreik F, Porat RM, Finkelstein R, Reuter H, Koschny R, Ganten T, Mogler C, Shibolet O, Hess J, Breuhahn K, Grunewald M, Schirmacher P, Vogel A, Terracciano L, Angel P, Ben-Neriah Y, Pikarsky E.

Cancer Discov. 2014 Jun;4(6):730-43. doi: 10.1158/2159-8290.CD-13-0782. Epub 2014 Mar 31.

40.

Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat.

Hu J, Srivastava K, Wieland M, Runge A, Mogler C, Besemfelder E, Terhardt D, Vogel MJ, Cao L, Korn C, Bartels S, Thomas M, Augustin HG.

Science. 2014 Jan 24;343(6169):416-9. doi: 10.1126/science.1244880.

PMID:
24458641
41.

Outcome and development of symptoms after orthotopic liver transplantation for Wilson disease.

Weiss KH, Schäfer M, Gotthardt DN, Angerer A, Mogler C, Schirmacher P, Schemmer P, Stremmel W, Sauer P.

Clin Transplant. 2013 Nov-Dec;27(6):914-22. doi: 10.1111/ctr.12259. Epub 2013 Oct 9.

PMID:
24118554
42.

Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin-2 expression in peri-tumourous liver correlates with increased survival.

Géraud C, Mogler C, Runge A, Evdokimov K, Lu S, Schledzewski K, Arnold B, Hämmerling G, Koch PS, Breuhahn K, Longerich T, Marx A, Weiss C, Damm F, Schmieder A, Schirmacher P, Augustin HG, Goerdt S.

Liver Int. 2013 Oct;33(9):1428-40. doi: 10.1111/liv.12262. Epub 2013 Jul 21.

PMID:
23870052
43.

[Severe bilateral keratomalacia].

Khoramnia R, Auffarth GU, Mogler C, Cordeiro SA, Scheuerle AF.

Ophthalmologe. 2013 Jan;110(1):61-4. doi: 10.1007/s00347-012-2706-9. German.

PMID:
23329120
44.

[Frozen section diagnostics in visceral surgery. Liver, bile ducts and pancreas].

Mogler C, Flechtenmacher C, Schirmacher P, Bergmann F.

Pathologe. 2012 Sep;33(5):413-23. doi: 10.1007/s00292-012-1602-z. Review. German.

PMID:
22892660
45.

Expression analysis of aldehyde dehydrogenase 1A1 (ALDH1A1) in colon and rectal cancer in association with prognosis and response to chemotherapy.

Kahlert C, Gaitzsch E, Steinert G, Mogler C, Herpel E, Hoffmeister M, Jansen L, Benner A, Brenner H, Chang-Claude J, Rahbari N, Schmidt T, Klupp F, Grabe N, Lahrmann B, Koch M, Halama N, Büchler M, Weitz J.

Ann Surg Oncol. 2012 Dec;19(13):4193-201. doi: 10.1245/s10434-012-2518-9. Epub 2012 Aug 10.

PMID:
22878609
46.

Penile methadone injection in suicidal intent: life-threatening and fatal for erectile function.

Prado LG, Huber J, Huber CG, Mogler C, Ehrenheim J, Nyarangi-Dix J, Pahernik S, Hohenfellner M.

J Androl. 2012 Sep-Oct;33(5):801-4. Epub 2012 Mar 8.

PMID:
22403280
47.

Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro.

Kahlert C, Lahes S, Radhakrishnan P, Dutta S, Mogler C, Herpel E, Brand K, Steinert G, Schneider M, Mollenhauer M, Reissfelder C, Klupp F, Fritzmann J, Wunder C, Benner A, Kloor M, Huth C, Contin P, Ulrich A, Koch M, Weitz J.

Clin Cancer Res. 2011 Dec 15;17(24):7654-63. doi: 10.1158/1078-0432.CCR-10-2816. Epub 2011 Oct 31.

48.

Effect of tissue perfusion on microwave ablation: experimental in vivo study in porcine kidneys.

Sommer CM, Koch V, Pap B, Bellemann N, Holzschuh M, Gehrig T, Shevchenko M, Arnegger FU, Nickel F, Mogler C, Zelzer S, Meinzer HP, Stampfl U, Kauczor HU, Radeleff BA.

J Vasc Interv Radiol. 2011 Dec;22(12):1751-7. doi: 10.1016/j.jvir.2011.07.020. Epub 2011 Oct 6.

PMID:
21982204
49.

Low expression of aldehyde dehydrogenase 1A1 (ALDH1A1) is a prognostic marker for poor survival in pancreatic cancer.

Kahlert C, Bergmann F, Beck J, Welsch T, Mogler C, Herpel E, Dutta S, Niemietz T, Koch M, Weitz J.

BMC Cancer. 2011 Jun 27;11:275. doi: 10.1186/1471-2407-11-275.

50.

Heparanase expression in head and neck squamous cell carcinomas is associated with reduced proliferation and improved survival.

Mogler C, Herold-Mende C, Dyckhoff G, Jenetzky E, Beckhove P, Helmke BM.

Histopathology. 2011 May;58(6):944-52. doi: 10.1111/j.1365-2559.2011.03834.x.

PMID:
21585429

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