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Items: 1 to 50 of 154

1.

Autosomal Dominant Hyper-IgE Syndrome Without Significantly Elevated IgE.

Larsen CS, Christiansen M, Mogensen TH.

J Clin Immunol. 2019 Aug 29. doi: 10.1007/s10875-019-00683-8. [Epub ahead of print] No abstract available.

PMID:
31468318
2.

Host Genetics, Innate Immune Responses, and Cellular Death Pathways in Poliomyelitis Patients.

Andersen NB, Larsen SM, Nissen SK, Jørgensen SE, Mardahl M, Christiansen M, Kay L, Mogensen TH.

Front Microbiol. 2019 Jul 9;10:1495. doi: 10.3389/fmicb.2019.01495. eCollection 2019.

3.

Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza.

Thomsen MM, Jørgensen SE, Storgaard M, Kristensen LS, Gjedsted J, Christiansen M, Gad HH, Hartmann R, Mogensen TH.

Eur J Immunol. 2019 Nov;49(11):2111-2114. doi: 10.1002/eji.201848083. No abstract available.

PMID:
31250433
4.

Defective interferon priming and impaired antiviral responses in a patient with an IRF7 variant and severe influenza.

Thomsen MM, Jørgensen SE, Gad HH, Storgaard M, Gjedsted J, Christiansen M, Hartmann R, Mogensen TH.

Med Microbiol Immunol. 2019 Dec;208(6):869-876. doi: 10.1007/s00430-019-00623-8. Epub 2019 Jun 6.

PMID:
31172279
5.

Impaired immune responses to herpesviruses and microbial ligands in patients with MonoMAC.

Mardahl M, Jørgensen SE, Schneider A, Raaschou-Jensen K, Holm M, Veirum J, Kristensen TK, Johansen IS, Christiansen M, Assing K, Mogensen TH.

Br J Haematol. 2019 Aug;186(3):471-476. doi: 10.1111/bjh.15947. Epub 2019 May 20.

PMID:
31106410
6.

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.

Kaleviste E, Saare M, Leahy TR, Bondet V, Duffy D, Mogensen TH, Jørgensen SE, Nurm H, Ip W, Davies EG, Sauer S, Syvänen AC, Milani L, Peterson P, Kisand K.

Eur J Immunol. 2019 May;49(5):790-800. doi: 10.1002/eji.201847955. Epub 2019 Mar 7.

PMID:
30801692
7.

IRF and STAT Transcription Factors - From Basic Biology to Roles in Infection, Protective Immunity, and Primary Immunodeficiencies.

Mogensen TH.

Front Immunol. 2019 Jan 8;9:3047. doi: 10.3389/fimmu.2018.03047. eCollection 2018. Review.

8.

Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules.

Nissen SK, Christiansen M, Helleberg M, Kjær K, Jørgensen SE, Gerstoft J, Katzenstein TL, Benfield T, Kronborg G, Larsen CS, Laursen A, Pedersen G, Jakobsen MR, Tolstrup M, Mogensen TH.

Sci Rep. 2018 Oct 15;8(1):15253. doi: 10.1038/s41598-018-33481-0.

9.

Varicella-zoster virus CNS vasculitis and RNA polymerase III gene mutation in identical twins.

Carter-Timofte ME, Hansen AF, Mardahl M, Fribourg S, Rapaport F, Zhang SY, Casanova JL, Paludan SR, Christiansen M, Larsen CS, Mogensen TH.

Neurol Neuroimmunol Neuroinflamm. 2018 Sep 7;5(6):e500. doi: 10.1212/NXI.0000000000000500. eCollection 2018 Nov.

10.

Severe capillary leak syndrome with cardiac arrest triggered by influenza virus infection.

Ebdrup L, Druey KM, Druey K, Mogensen TH.

BMJ Case Rep. 2018 Aug 29;2018. pii: bcr-2018-226108. doi: 10.1136/bcr-2018-226108. Erratum in: BMJ Case Rep. 2018 Oct 3;2018:. Druey K [corrected to Druey KM].

11.

RNA Polymerase III as a Gatekeeper to Prevent Severe VZV Infections.

Carter-Timofte ME, Paludan SR, Mogensen TH.

Trends Mol Med. 2018 Oct;24(10):904-915. doi: 10.1016/j.molmed.2018.07.009. Epub 2018 Aug 13. Review.

PMID:
30115567
12.

Identification of a novel mutation in the factor VIII gene causing severe haemophilia A.

Nissen SK, Laursen AL, Poulsen LH, Mogensen TH.

BMC Hematol. 2018 Jul 31;18:17. doi: 10.1186/s12878-018-0113-4. eCollection 2018.

13.

Autoinflammatoriske periodiske febersyndromer.

Mogensen TH.

Ugeskr Laeger. 2018 Jul 23;180(30). pii: V69816. Danish. No abstract available.

PMID:
30037380
14.

Mutations in RNA Polymerase III genes and defective DNA sensing in adults with varicella-zoster virus CNS infection.

Carter-Timofte ME, Hansen AF, Christiansen M, Paludan SR, Mogensen TH.

Genes Immun. 2019 Mar;20(3):214-223. doi: 10.1038/s41435-018-0027-y. Epub 2018 May 1.

PMID:
29728610
15.

Multiple Homozygous Variants in the STING-Encoding TMEM173 Gene in HIV Long-Term Nonprogressors.

Nissen SK, Pedersen JG, Helleberg M, Kjær K, Thavachelvam K, Obel N, Tolstrup M, Jakobsen MR, Mogensen TH.

J Immunol. 2018 May 15;200(10):3372-3382. doi: 10.4049/jimmunol.1701284. Epub 2018 Apr 9.

16.

Defective RNA sensing by RIG-I in severe influenza virus infection.

Jørgensen SE, Christiansen M, Ryø LB, Gad HH, Gjedsted J, Staeheli P, Mikkelsen JG, Storgaard M, Hartmann R, Mogensen TH.

Clin Exp Immunol. 2018 Jun;192(3):366-376. doi: 10.1111/cei.13120. Epub 2018 Mar 24.

17.

Frequently used bioinformatics tools overestimate the damaging effect of allelic variants.

Andersen LL, Terczyńska-Dyla E, Mørk N, Scavenius C, Enghild JJ, Höning K, Hornung V, Christiansen M, Mogensen TH, Hartmann R.

Genes Immun. 2019 Jan;20(1):10-22. doi: 10.1038/s41435-017-0002-z. Epub 2017 Dec 4.

PMID:
29217828
18.

Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-β Expression.

Eriksson K, Svensson A, Hait AS, Schlüter K, Tunbäck P, Nordström I, Padyukov L, Liljeqvist JÅ, Mogensen TH, Paludan SR.

J Immunol. 2017 Oct 15;199(8):2613-2617. doi: 10.4049/jimmunol.1700385. Epub 2017 Sep 11.

19.

Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections.

Ogunjimi B, Zhang SY, Sørensen KB, Skipper KA, Carter-Timofte M, Kerner G, Luecke S, Prabakaran T, Cai Y, Meester J, Bartholomeus E, Bolar NA, Vandeweyer G, Claes C, Sillis Y, Lorenzo L, Fiorenza RA, Boucherit S, Dielman C, Heynderickx S, Elias G, Kurotova A, Auwera AV, Verstraete L, Lagae L, Verhelst H, Jansen A, Ramet J, Suls A, Smits E, Ceulemans B, Van Laer L, Plat Wilson G, Kreth J, Picard C, Von Bernuth H, Fluss J, Chabrier S, Abel L, Mortier G, Fribourg S, Mikkelsen JG, Casanova JL, Paludan SR, Mogensen TH.

J Clin Invest. 2017 Sep 1;127(9):3543-3556. doi: 10.1172/JCI92280. Epub 2017 Aug 7.

20.

Identification and Characterization of a Nationwide Danish Adult Common Variable Immunodeficiency Cohort.

Westh L, Mogensen TH, Dalgaard LS, Bernth Jensen JM, Katzenstein T, Hansen AE, Larsen OD, Terpling S, Nielsen TL, Larsen CS.

Scand J Immunol. 2017 Jun;85(6):450-461. doi: 10.1111/sji.12551.

21.

[Herpes simplex encephalitis].

Jørgensen LK, Mogensen TH.

Ugeskr Laeger. 2017 Jan 9;179(2). pii: V07160478. Review. Danish.

PMID:
28074766
22.

Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.

Reinert LS, Lopušná K, Winther H, Sun C, Thomsen MK, Nandakumar R, Mogensen TH, Meyer M, Vægter C, Nyengaard JR, Fitzgerald KA, Paludan SR.

Nat Commun. 2016 Nov 10;7:13348. doi: 10.1038/ncomms13348.

23.

[Obesity – can health professionals solve the problem?].

Mogensen T.

Ugeskr Laeger. 2016 Oct 31;178(44). pii: V68755. Danish. No abstract available.

PMID:
27808044
24.

Incidence and mortality of herpes simplex encephalitis in Denmark: A nationwide registry-based cohort study.

Jørgensen LK, Dalgaard LS, Østergaard LJ, Nørgaard M, Mogensen TH.

J Infect. 2017 Jan;74(1):42-49. doi: 10.1016/j.jinf.2016.09.004. Epub 2016 Oct 4.

PMID:
27717782
25.

XIAP deficiency and MEFV variants resulting in an autoinflammatory lymphoproliferative syndrome.

Christiansen M, Ammann S, Speckmann C, Mogensen TH.

BMJ Case Rep. 2016 Sep 28;2016. pii: bcr2016216922. doi: 10.1136/bcr-2016-216922.

26.

A novel lozenge containing bupivacaine as topical alleviation of oral mucositis pain in patients with head and neck cancer: a pilot study.

Mogensen S, Treldal C, Sveinsdottir K, Jensen K, Kristensen CA, Mogensen TS, Petersen J, Andersen O.

Pain Rep. 2016 Sep 30;1(3):e571. doi: 10.1097/PR9.0000000000000571. eCollection 2016 Sep.

27.

Ectodermal dysplasia with immunodeficiency caused by a branch-point mutation in IKBKG/NEMO.

Jørgensen SE, Bøttger P, Kofod-Olsen E, Holm M, Mørk N, Ørntoft TF, Sørensen UBS, Bernth-Jensen JM, Herlin T, Veirum J, Larsen CS, Østergaard L, Hartmann R, Christiansen M, Mogensen TH.

J Allergy Clin Immunol. 2016 Dec;138(6):1706-1709.e4. doi: 10.1016/j.jaci.2016.05.030. Epub 2016 Jun 29. No abstract available.

PMID:
27477329
28.

Validity of the coding for herpes simplex encephalitis in the Danish National Patient Registry.

Jørgensen LK, Dalgaard LS, Østergaard LJ, Andersen NS, Nørgaard M, Mogensen TH.

Clin Epidemiol. 2016 May 31;8:133-40. doi: 10.2147/CLEP.S104379. eCollection 2016.

29.

HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression.

Christensen MH, Jensen SB, Miettinen JJ, Luecke S, Prabakaran T, Reinert LS, Mettenleiter T, Chen ZJ, Knipe DM, Sandri-Goldin RM, Enquist LW, Hartmann R, Mogensen TH, Rice SA, Nyman TA, Matikainen S, Paludan SR.

EMBO J. 2016 Jul 1;35(13):1385-99. doi: 10.15252/embj.201593458. Epub 2016 May 27.

30.

New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits.

Møller-Sørensen H, Korshin A, Mogensen T, Høiby N.

J Hosp Infect. 2016 Apr;92(4):337-9. doi: 10.1016/j.jhin.2015.09.012. Epub 2015 Oct 22.

PMID:
26597634
31.

Altered fraction of regulatory B and T cells is correlated with autoimmune phenomena and splenomegaly in patients with CVID.

Kofod-Olsen E, Jørgensen SE, Nissen SK, Westh L, Møller BK, Østergaard L, Larsen CS, Mogensen TH.

Clin Immunol. 2016 Jan;162:49-57. doi: 10.1016/j.clim.2015.11.003. Epub 2015 Nov 14.

PMID:
26586095
32.

Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis.

Mørk N, Kofod-Olsen E, Sørensen KB, Bach E, Ørntoft TF, Østergaard L, Paludan SR, Christiansen M, Mogensen TH.

Genes Immun. 2015 Dec;16(8):552-66. doi: 10.1038/gene.2015.46. Epub 2015 Oct 29.

PMID:
26513235
33.

A STAT1-gain-of-function mutation causing Th17 deficiency with chronic mucocutaneous candidiasis, psoriasiform hyperkeratosis and dermatophytosis.

Nielsen J, Kofod-Olsen E, Spaun E, Larsen CS, Christiansen M, Mogensen TH.

BMJ Case Rep. 2015 Oct 22;2015. pii: bcr2015211372. doi: 10.1136/bcr-2015-211372. Erratum in: BMJ Case Rep. 2015;2015. pii: bcr2015211372corr1. doi: 10.1136/bcr-2015-211372corr1.

34.

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

Andersen LL, Mørk N, Reinert LS, Kofod-Olsen E, Narita R, Jørgensen SE, Skipper KA, Höning K, Gad HH, Østergaard L, Ørntoft TF, Hornung V, Paludan SR, Mikkelsen JG, Fujita T, Christiansen M, Hartmann R, Mogensen TH.

J Exp Med. 2015 Aug 24;212(9):1371-9. doi: 10.1084/jem.20142274. Epub 2015 Jul 27.

35.

Primary Immunodeficiencies with Elevated IgE.

Mogensen TH.

Int Rev Immunol. 2016;35(1):39-56. doi: 10.3109/08830185.2015.1027820. Epub 2015 May 13. Review.

PMID:
25970001
36.

Screeningens væsen og status.

Mogensen T.

Ugeskr Laeger. 2014 Jun 9;176(12). pii: V66356. Danish. No abstract available.

PMID:
25096931
37.

Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates with chronic immune activation.

Nissen SK, Højen JF, Andersen KL, Kofod-Olsen E, Berg RK, Paludan SR, Østergaard L, Jakobsen MR, Tolstrup M, Mogensen TH.

Clin Exp Immunol. 2014 Jul;177(1):295-309. doi: 10.1111/cei.12317.

38.

Common variable immunodeficiency unmasked by treatment of immune thrombocytopenic purpura with Rituximab.

Mogensen TH, Bernth-Jensen JM, Petersen CC, Petersen MS, Nyvold C, Gadegaard KH, Hokland M, Hokland P, Larsen CS.

BMC Hematol. 2013 Apr 11;13(1):4. doi: 10.1186/2052-1839-13-4.

39.

Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA.

Chiliveru S, Rahbek SH, Jensen SK, Jørgensen SE, Nissen SK, Christiansen SH, Mogensen TH, Jakobsen MR, Iversen L, Johansen C, Paludan SR.

J Immunol. 2014 Mar 1;192(5):2395-404. doi: 10.4049/jimmunol.1302120. Epub 2014 Jan 31.

40.

Misdiagnosed amoebic colitis leading to severe dysentery and necrotizing colitis--report of a case and review of the literature.

Mogensen TH, Christiansen JJ, Eivindson MV, Larsen CS, Tøttrup A.

Scand J Infect Dis. 2014 Mar;46(3):235-9. doi: 10.3109/00365548.2013.871646. Epub 2014 Jan 23. Review.

PMID:
24450838
41.

T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication.

Berg RK, Rahbek SH, Kofod-Olsen E, Holm CK, Melchjorsen J, Jensen DG, Hansen AL, Jørgensen LB, Ostergaard L, Tolstrup M, Larsen CS, Paludan SR, Jakobsen MR, Mogensen TH.

PLoS One. 2014 Jan 3;9(1):e84513. doi: 10.1371/journal.pone.0084513. eCollection 2014.

42.

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.

Jakobsen MR, Bak RO, Andersen A, Berg RK, Jensen SB, Tengchuan J, Laustsen A, Hansen K, Ostergaard L, Fitzgerald KA, Xiao TS, Mikkelsen JG, Mogensen TH, Paludan SR.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):E4571-80. doi: 10.1073/pnas.1311669110. Epub 2013 Oct 23. Erratum in: Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19651. Jin, Tengchuan [corrected to Tengchuan, Jin].

43.
44.

Characterization of HIV-1 infection and innate sensing in different types of primary human monocyte-derived macrophages.

Diget EA, Zuwala K, Berg RK, Laursen RR, Søby S, Østergaard L, Melchjorsen J, Mogensen TH.

Mediators Inflamm. 2013;2013:208412. doi: 10.1155/2013/208412. Epub 2013 Jan 28.

45.

Caught in translation: innate restriction of HIV mRNA translation by a schlafen family protein.

Jakobsen MR, Mogensen TH, Paludan SR.

Cell Res. 2013 Mar;23(3):320-2. doi: 10.1038/cr.2012.155. Epub 2012 Nov 6.

46.

Outcomes of a classroom-based team training intervention for multi-professional hospital staff.

Rabøl LI, McPhail M, Bjørn B, Anhøj J, Mogensen T, Østergaard D, Andersen HB.

Med Teach. 2012;34(10):868-9. doi: 10.3109/0142159X.2012.716182. Epub 2012 Sep 26. No abstract available.

PMID:
23009277
47.

Identification of a novel STAT3 mutation in a patient with hyper-IgE syndrome.

Mogensen TH, Jakobsen MA, Larsen CS.

Scand J Infect Dis. 2013 Mar;45(3):235-8. doi: 10.3109/00365548.2012.715750. Epub 2012 Sep 19.

PMID:
22992060
48.

A new method to facilitate oro-tracheal intubation of awake patients: a pilot study.

Mogensen S, Pulis S, Kristensen BB, Ravn L, Treldal C, Rasmussen M, Mogensen T, Andersen O.

Eur J Anaesthesiol. 2012 Nov;29(11):546-7. doi: 10.1097/EJA.0b013e328357e4e5. No abstract available.

PMID:
22955296
49.

Genetical analysis of all Danish patients diagnosed with chronic granulomatous disease.

Jakobsen MA, Katzenstein TL, Valerius NH, Roos D, Fisker N, Mogensen TH, Jensen PØ, Barington T.

Scand J Immunol. 2012 Nov;76(5):505-11. doi: 10.1111/j.1365-3083.2012.02771.x.

50.

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice.

Reinert LS, Harder L, Holm CK, Iversen MB, Horan KA, Dagnæs-Hansen F, Ulhøi BP, Holm TH, Mogensen TH, Owens T, Nyengaard JR, Thomsen AR, Paludan SR.

J Clin Invest. 2012 Apr;122(4):1368-76. doi: 10.1172/JCI60893. Epub 2012 Mar 19.

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