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Items: 1 to 50 of 98

1.

Talin is required to increase stiffness of focal molecular complex in its early formation process.

Nakao N, Maki K, Mofrad MRK, Adachi T.

Biochem Biophys Res Commun. 2019 Oct 20;518(3):579-583. doi: 10.1016/j.bbrc.2019.08.091. Epub 2019 Aug 23.

PMID:
31451222
2.

Structural Basis of the Differential Binding of Engineered Knottins to Integrins αVβ3 and α5β1.

Van Agthoven JF, Shams H, Cochran FV, Alonso JL, Kintzing JR, Garakani K, Adair BD, Xiong JP, Mofrad MRK, Cochran JR, Arnaout MA.

Structure. 2019 Sep 3;27(9):1443-1451.e6. doi: 10.1016/j.str.2019.06.011. Epub 2019 Jul 25.

PMID:
31353240
3.

Deep echocardiography: data-efficient supervised and semi-supervised deep learning towards automated diagnosis of cardiac disease.

Madani A, Ong JR, Tibrewal A, Mofrad MRK.

NPJ Digit Med. 2018 Oct 18;1:59. doi: 10.1038/s41746-018-0065-x. eCollection 2018.

4.

Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation.

Didonna A, Cantó E, Shams H, Isobe N, Zhao C, Caillier SJ, Condello C, Yamate-Morgan H, Tiwari-Woodruff SK, Mofrad MRK, Hauser SL, Oksenberg JR.

J Autoimmun. 2019 Jul;101:56-69. doi: 10.1016/j.jaut.2019.04.003. Epub 2019 Apr 19.

PMID:
31010726
5.

The nucleus feels the force, LINCed in or not!

Jahed Z, Mofrad MR.

Curr Opin Cell Biol. 2019 Jun;58:114-119. doi: 10.1016/j.ceb.2019.02.012. Epub 2019 Apr 16. Review.

PMID:
31002996
6.

Role of KASH domain lengths in the regulation of LINC complexes.

Jahed Z, Hao H, Thakkar V, Vu UT, Valdez VA, Rathish A, Tolentino C, Kim SCJ, Fadavi D, Starr DA, Mofrad MRK.

Mol Biol Cell. 2019 Jul 22;30(16):2076-2086. doi: 10.1091/mbc.E19-02-0079. Epub 2019 Apr 17.

7.
8.

Kindlin Is Mechanosensitive: Force-Induced Conformational Switch Mediates Cross-Talk among Integrins.

Jahed Z, Haydari Z, Rathish A, Mofrad MRK.

Biophys J. 2019 Mar 19;116(6):1011-1024. doi: 10.1016/j.bpj.2019.01.038. Epub 2019 Feb 7.

PMID:
30819565
9.

DiTaxa: nucleotide-pair encoding of 16S rRNA for host phenotype and biomarker detection.

Asgari E, Münch PC, Lesker TR, McHardy AC, Mofrad MRK.

Bioinformatics. 2019 Jul 15;35(14):2498-2500. doi: 10.1093/bioinformatics/bty954.

PMID:
30500871
10.

Conserved SUN-KASH Interfaces Mediate LINC Complex-Dependent Nuclear Movement and Positioning.

Cain NE, Jahed Z, Schoenhofen A, Valdez VA, Elkin B, Hao H, Harris NJ, Herrera LA, Woolums BM, Mofrad MRK, Luxton GWG, Starr DA.

Curr Biol. 2018 Oct 8;28(19):3086-3097.e4. doi: 10.1016/j.cub.2018.08.001. Epub 2018 Sep 20.

11.

MicroPheno: predicting environments and host phenotypes from 16S rRNA gene sequencing using a k-mer based representation of shallow sub-samples.

Asgari E, Garakani K, McHardy AC, Mofrad MRK.

Bioinformatics. 2019 Mar 15;35(6):1082. doi: 10.1093/bioinformatics/bty652. No abstract available.

12.

A molecular model for LINC complex regulation: activation of SUN2 for KASH binding.

Jahed Z, Vu UT, Fadavi D, Ke H, Rathish A, Kim SCJ, Feng W, Mofrad MRK.

Mol Biol Cell. 2018 Aug 8;29(16):2012-2023. doi: 10.1091/mbc.E18-04-0266. Epub 2018 Jul 11.

13.

MicroPheno: predicting environments and host phenotypes from 16S rRNA gene sequencing using a k-mer based representation of shallow sub-samples.

Asgari E, Garakani K, McHardy AC, Mofrad MRK.

Bioinformatics. 2018 Jul 1;34(13):i32-i42. doi: 10.1093/bioinformatics/bty296. Erratum in: Bioinformatics. 2019 Mar 15;35(6):1082.

14.

Agent-Based Modeling in Molecular Systems Biology.

Soheilypour M, Mofrad MRK.

Bioessays. 2018 Jul;40(7):e1800020. doi: 10.1002/bies.201800020. Epub 2018 Jun 8. Review.

15.

Molecular Insights into the Mechanisms of SUN1 Oligomerization in the Nuclear Envelope.

Jahed Z, Fadavi D, Vu UT, Asgari E, Luxton GWG, Mofrad MRK.

Biophys J. 2018 Mar 13;114(5):1190-1203. doi: 10.1016/j.bpj.2018.01.015.

16.

Quality control of mRNAs at the entry of the nuclear pore: Cooperation in a complex molecular system.

Soheilypour M, Mofrad MRK.

Nucleus. 2018 Jan 1;9(1):202-211. doi: 10.1080/19491034.2018.1439304. Review.

17.

ProtDataTherm: A database for thermostability analysis and engineering of proteins.

Pezeshgi Modarres H, Mofrad MR, Sanati-Nezhad A.

PLoS One. 2018 Jan 29;13(1):e0191222. doi: 10.1371/journal.pone.0191222. eCollection 2018.

18.

The "Stressful" Life of Cell Adhesion Molecules: On the Mechanosensitivity of Integrin Adhesome.

Shams H, Hoffman BD, Mofrad MRK.

J Biomech Eng. 2018 Feb 1;140(2). doi: 10.1115/1.4038812. Review.

19.

A strain-based finite element model for calcification progression in aortic valves.

Arzani A, Mofrad MRK.

J Biomech. 2017 Dec 8;65:216-220. doi: 10.1016/j.jbiomech.2017.10.014.

PMID:
29100595
20.

α-Actinin Induces a Kink in the Transmembrane Domain of β3-Integrin and Impairs Activation via Talin.

Shams H, Mofrad MRK.

Biophys J. 2017 Aug 22;113(4):948-956. doi: 10.1016/j.bpj.2017.06.064.

21.

Consistent trilayer biomechanical modeling of aortic valve leaflet tissue.

Bakhaty AA, Govindjee S, Mofrad MRK.

J Biomech. 2017 Aug 16;61:1-10. doi: 10.1016/j.jbiomech.2017.06.014. Epub 2017 Aug 9.

PMID:
28830591
22.

Mechanical Contact Characteristics of PC3 Human Prostate Cancer Cells on Complex-Shaped Silicon Micropillars.

Seo BB, Jahed Z, Coggan JA, Chau YY, Rogowski JL, Gu FX, Wen W, Mofrad MRK, Tsui TY.

Materials (Basel). 2017 Aug 2;10(8). pii: E892. doi: 10.3390/ma10080892.

23.

Molecular mechanics of Staphylococcus aureus adhesin, CNA, and the inhibition of bacterial adhesion by stretching collagen.

Madani A, Garakani K, Mofrad MRK.

PLoS One. 2017 Jun 30;12(6):e0179601. doi: 10.1371/journal.pone.0179601. eCollection 2017.

24.

Mechanosensitive Conformation of Vinculin Regulates Its Binding to MAPK1.

Garakani K, Shams H, Mofrad MRK.

Biophys J. 2017 May 9;112(9):1885-1893. doi: 10.1016/j.bpj.2017.03.039.

25.

Bacterial Networks on Hydrophobic Micropillars.

Jahed Z, Shahsavan H, Verma MS, Rogowski JL, Seo BB, Zhao B, Tsui TY, Gu FX, Mofrad MR.

ACS Nano. 2017 Jan 24;11(1):675-683. doi: 10.1021/acsnano.6b06985. Epub 2017 Jan 9.

26.
27.

Gelatin/chondroitin sulfate nanofibrous scaffolds for stimulation of wound healing: In-vitro and in-vivo study.

Pezeshki-Modaress M, Mirzadeh H, Zandi M, Rajabi-Zeleti S, Sodeifi N, Aghdami N, Mofrad MRK.

J Biomed Mater Res A. 2017 Jul;105(7):2020-2034. doi: 10.1002/jbm.a.35890. Epub 2017 May 10.

PMID:
27588562
28.

Interferon Beta: From Molecular Level to Therapeutic Effects.

Haji Abdolvahab M, Mofrad MR, Schellekens H.

Int Rev Cell Mol Biol. 2016;326:343-72. doi: 10.1016/bs.ircmb.2016.06.001. Epub 2016 Jul 20. Review.

PMID:
27572132
29.

Differential Collective- and Single-Cell Behaviors on Silicon Micropillar Arrays.

Jahed Z, Zareian R, Chau YY, Seo BB, West M, Tsui TY, Wen W, Mofrad MR.

ACS Appl Mater Interfaces. 2016 Sep 14;8(36):23604-13. doi: 10.1021/acsami.6b08668. Epub 2016 Aug 29.

30.

The LINC and NPC relationship - it's complicated!

Jahed Z, Soheilypour M, Peyro M, Mofrad MR.

J Cell Sci. 2016 Sep 1;129(17):3219-29. doi: 10.1242/jcs.184184. Epub 2016 Aug 16. Review.

31.
32.

Micro and nanotechnologies in heart valve tissue engineering.

Hasan A, Saliba J, Pezeshgi Modarres H, Bakhaty A, Nasajpour A, Mofrad MRK, Sanati-Nezhad A.

Biomaterials. 2016 Oct;103:278-292. doi: 10.1016/j.biomaterials.2016.07.001. Epub 2016 Jul 2. Review.

PMID:
27414719
33.

Dynamic Regulation of α-Actinin's Calponin Homology Domains on F-Actin.

Shams H, Golji J, Garakani K, Mofrad MR.

Biophys J. 2016 Mar 29;110(6):1444-55. doi: 10.1016/j.bpj.2016.02.024.

34.

Nucleoporin's Like Charge Regions Are Major Regulators of FG Coverage and Dynamics Inside the Nuclear Pore Complex.

Peyro M, Soheilypour M, Ghavami A, Mofrad MR.

PLoS One. 2015 Dec 11;10(12):e0143745. doi: 10.1371/journal.pone.0143745. eCollection 2015.

35.

Continuous Distributed Representation of Biological Sequences for Deep Proteomics and Genomics.

Asgari E, Mofrad MR.

PLoS One. 2015 Nov 10;10(11):e0141287. doi: 10.1371/journal.pone.0141287. eCollection 2015.

36.

Evolutionarily Conserved Sequence Features Regulate the Formation of the FG Network at the Center of the Nuclear Pore Complex.

Peyro M, Soheilypour M, Lee BL, Mofrad MR.

Sci Rep. 2015 Nov 6;5:15795. doi: 10.1038/srep15795.

37.

A Disulfide Bond Is Required for the Transmission of Forces through SUN-KASH Complexes.

Jahed Z, Shams H, Mofrad MR.

Biophys J. 2015 Aug 4;109(3):501-9. doi: 10.1016/j.bpj.2015.06.057.

38.

Torsional behavior of axonal microtubule bundles.

Lazarus C, Soheilypour M, Mofrad MR.

Biophys J. 2015 Jul 21;109(2):231-9. doi: 10.1016/j.bpj.2015.06.029.

39.

Cooperation within von Willebrand factors enhances adsorption mechanism.

Heidari M, Mehrbod M, Ejtehadi MR, Mofrad MR.

J R Soc Interface. 2015 Aug 6;12(109):20150334. doi: 10.1098/rsif.2015.0334.

40.

Mechanisms of integrin and filamin binding and their interplay with talin during early focal adhesion formation.

Truong T, Shams H, Mofrad MR.

Integr Biol (Camb). 2015 Oct;7(10):1285-96. doi: 10.1039/c5ib00133a. Epub 2015 Jul 9.

PMID:
26156744
41.

Coupled Simulation of Heart Valves: Applications to Clinical Practice.

Bakhaty AA, Mofrad MR.

Ann Biomed Eng. 2015 Jul;43(7):1626-39. doi: 10.1007/s10439-015-1348-x. Epub 2015 Jun 23.

PMID:
26101029
42.

Buckling behavior of individual and bundled microtubules.

Soheilypour M, Peyro M, Peter SJ, Mofrad MRK.

Biophys J. 2015 Apr 7;108(7):1718-1726. doi: 10.1016/j.bpj.2015.01.030.

43.

The interaction of RNA helicase DDX3 with HIV-1 Rev-CRM1-RanGTP complex during the HIV replication cycle.

Mahboobi SH, Javanpour AA, Mofrad MR.

PLoS One. 2015 Feb 27;10(2):e0112969. doi: 10.1371/journal.pone.0112969. eCollection 2015.

44.

Directional migration and differentiation of neural stem cells within three-dimensional microenvironments.

Shamloo A, Heibatollahi M, Mofrad MR.

Integr Biol (Camb). 2015 Mar;7(3):335-44. doi: 10.1039/c4ib00144c. Epub 2015 Jan 30.

PMID:
25633746
45.

Emerging trends in heart valve engineering: Part I. Solutions for future.

Kheradvar A, Groves EM, Dasi LP, Alavi SH, Tranquillo R, Grande-Allen KJ, Simmons CA, Griffith B, Falahatpisheh A, Goergen CJ, Mofrad MR, Baaijens F, Little SH, Canic S.

Ann Biomed Eng. 2015 Apr;43(4):833-43. doi: 10.1007/s10439-014-1209-z. Epub 2014 Dec 9. Review.

PMID:
25488074
46.

Emerging trends in heart valve engineering: Part II. Novel and standard technologies for aortic valve replacement.

Kheradvar A, Groves EM, Goergen CJ, Alavi SH, Tranquillo R, Simmons CA, Dasi LP, Grande-Allen KJ, Mofrad MR, Falahatpisheh A, Griffith B, Baaijens F, Little SH, Canic S.

Ann Biomed Eng. 2015 Apr;43(4):844-57. doi: 10.1007/s10439-014-1191-5. Epub 2014 Dec 2. Review.

PMID:
25449148
47.

The talin dimer structure orientation is mechanically regulated.

Golji J, Mofrad MRK.

Biophys J. 2014 Oct 21;107(8):1802-1809. doi: 10.1016/j.bpj.2014.08.038.

48.

Emerging trends in heart valve engineering: Part III. Novel technologies for mitral valve repair and replacement.

Kheradvar A, Groves EM, Simmons CA, Griffith B, Alavi SH, Tranquillo R, Dasi LP, Falahatpisheh A, Grande-Allen KJ, Goergen CJ, Mofrad MR, Baaijens F, Canic S, Little SH.

Ann Biomed Eng. 2015 Apr;43(4):858-70. doi: 10.1007/s10439-014-1129-y. Epub 2014 Oct 7. Review.

PMID:
25287646
49.

An agent-based model for mRNA export through the nuclear pore complex.

Azimi M, Bulat E, Weis K, Mofrad MR.

Mol Biol Cell. 2014 Nov 5;25(22):3643-53. doi: 10.1091/mbc.E14-06-1065. Epub 2014 Sep 24.

50.

Cell responses to metallic nanostructure arrays with complex geometries.

Jahed Z, Molladavoodi S, Seo BB, Gorbet M, Tsui TY, Mofrad MR.

Biomaterials. 2014 Nov;35(34):9363-71. doi: 10.1016/j.biomaterials.2014.07.022. Epub 2014 Aug 11.

PMID:
25123921

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