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Items: 1 to 50 of 148

1.

Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children.

Cuthbertson L, Oo SWC, Cox MJ, Khoo SK, Cox DW, Chidlow G, Franks K, Prastanti F, Borland ML, Gern JE, Smith DW, Bizzintino JA, Laing IA, Le Souëf PN, Moffatt MF, Cookson WOC.

PLoS One. 2019 Oct 17;14(10):e0223990. doi: 10.1371/journal.pone.0223990. eCollection 2019.

2.

Metabolomic, transcriptomic and genetic integrative analysis reveals important roles of adenosine diphosphate in haemostasis and platelet activation in non-small-cell lung cancer.

Hoang LT, Domingo-Sabugo C, Starren ES, Willis-Owen SAG, Morris-Rosendahl DJ, Nicholson AG, Cookson WOCM, Moffatt MF.

Mol Oncol. 2019 Aug 28. doi: 10.1002/1878-0261.12568. [Epub ahead of print]

3.

Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood.

Sugier PE, Sarnowski C, Granell R, Laprise C, Ege MJ, Margaritte-Jeannin P, Dizier MH, Minelli C, Moffatt MF, Lathrop M, Cookson WOCM, Henderson AJ, von Mutius E, Kogevinas M, Demenais F, Bouzigon E.

Clin Exp Allergy. 2019 Oct;49(10):1342-1351. doi: 10.1111/cea.13476.

PMID:
31379025
4.

EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype.

Ciano M, Mantellato G, Connolly M, Paul-Clark M, Willis-Owen S, Moffatt MF, Cookson WOCM, Mitchell JA, Polkey MI, Hughes SM, Kemp PR, Natanek SA.

Sci Rep. 2019 Jun 25;9(1):9218. doi: 10.1038/s41598-019-45567-4.

5.

Longitudinal development of the airway microbiota in infants with cystic fibrosis.

Ahmed B, Cox MJ, Cuthbertson L, James P, Cookson WOC, Davies JC, Moffatt MF, Bush A.

Sci Rep. 2019 Mar 26;9(1):5143. doi: 10.1038/s41598-019-41597-0.

6.

A Haemophilus sp. dominates the microbiota of sputum from UK adults with non-severe community acquired pneumonia and chronic lung disease.

Wootton DG, Cox MJ, Gloor GB, Litt D, Hoschler K, German E, Court J, Eneje O, Keogan L, Macfarlane L, Wilks S, Diggle PJ, Woodhead M, Moffatt MF, Cookson WOC, Gordon SB.

Sci Rep. 2019 Feb 20;9(1):2388. doi: 10.1038/s41598-018-38090-5.

7.

Author Correction: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.

Dunning J, Blankley S, Hoang LT, Cox M, Graham CM, James PL, Bloom CI, Chaussabel D, Banchereau J, Brett SJ; MOSAIC Investigators, Moffatt MF, O'Garra A, Openshaw PJM.

Nat Immunol. 2019 Mar;20(3):373. doi: 10.1038/s41590-019-0328-y.

8.

Profiling mycobacterial communities in pulmonary nontuberculous mycobacterial disease.

Cowman SA, James P, Wilson R, Cookson WOC, Moffatt MF, Loebinger MR.

PLoS One. 2018 Dec 11;13(12):e0208018. doi: 10.1371/journal.pone.0208018. eCollection 2018.

9.

The ORMDL3 Asthma Gene Regulates ICAM1 and Has Multiple Effects on Cellular Inflammation.

Zhang Y, Willis-Owen SAG, Spiegel S, Lloyd CM, Moffatt MF, Cookson WOCM.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):478-488. doi: 10.1164/rccm.201803-0438OC.

10.

The Genetics and Genomics of Asthma.

Willis-Owen SAG, Cookson WOC, Moffatt MF.

Annu Rev Genomics Hum Genet. 2018 Aug 31;19:223-246. doi: 10.1146/annurev-genom-083117-021651.

PMID:
30169121
11.

COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix.

Willis-Owen SAG, Thompson A, Kemp PR, Polkey MI, Cookson WOCM, Moffatt MF, Natanek SA.

Sci Rep. 2018 Aug 15;8(1):12165. doi: 10.1038/s41598-018-29789-6.

12.

Comparison of the upper and lower airway microbiota in children with chronic lung diseases.

Ahmed B, Cox MJ, Cuthbertson L, James PL, Cookson WOC, Davies JC, Moffatt MF, Bush A.

PLoS One. 2018 Aug 2;13(8):e0201156. doi: 10.1371/journal.pone.0201156. eCollection 2018.

13.

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.

Singanayagam A, Glanville N, Girkin JL, Ching YM, Marcellini A, Porter JD, Toussaint M, Walton RP, Finney LJ, Aniscenko J, Zhu J, Trujillo-Torralbo MB, Calderazzo MA, Grainge C, Loo SL, Veerati PC, Pathinayake PS, Nichol KS, Reid AT, James PL, Solari R, Wark PAB, Knight DA, Moffatt MF, Cookson WO, Edwards MR, Mallia P, Bartlett NW, Johnston SL.

Nat Commun. 2018 Jun 8;9(1):2229. doi: 10.1038/s41467-018-04574-1.

14.

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.

Dunning J, Blankley S, Hoang LT, Cox M, Graham CM, James PL, Bloom CI, Chaussabel D, Banchereau J, Brett SJ, Moffatt MF, O'Garra A, Openshaw PJM; MOSAIC Investigators.

Nat Immunol. 2018 Jun;19(6):625-635. doi: 10.1038/s41590-018-0111-5. Epub 2018 May 18. Erratum in: Nat Immunol. 2019 Mar;20(3):373.

15.

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Xu CJ, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, Gehring U, Mason D, Chatzi L, Basterrechea M, Llop S, Torrent M, Forastiere F, Fantini MP, Carlsen KCL, Haahtela T, Morin A, Kerkhof M, Merid SK, van Rijkom B, Jankipersadsing SA, Bonder MJ, Ballereau S, Vermeulen CJ, Aguirre-Gamboa R, de Jongste JC, Smit HA, Kumar A, Pershagen G, Guerra S, Garcia-Aymerich J, Greco D, Reinius L, McEachan RRC, Azad R, Hovland V, Mowinckel P, Alenius H, Fyhrquist N, Lemonnier N, Pellet J, Auffray C; BIOS Consortium, van der Vlies P, van Diemen CC, Li Y, Wijmenga C, Netea MG, Moffatt MF, Cookson WOCM, Anto JM, Bousquet J, Laatikainen T, Laprise C, Carlsen KH, Gori D, Porta D, Iñiguez C, Bilbao JR, Kogevinas M, Wright J, Brunekreef B, Kere J, Nawijn MC, Annesi-Maesano I, Sunyer J, Melén E, Koppelman GH.

Lancet Respir Med. 2018 May;6(5):379-388. doi: 10.1016/S2213-2600(18)30052-3. Epub 2018 Feb 26.

16.

Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota.

Groves HT, Cuthbertson L, James P, Moffatt MF, Cox MJ, Tregoning JS.

Front Immunol. 2018 Feb 12;9:182. doi: 10.3389/fimmu.2018.00182. eCollection 2018.

17.

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma.

Zhang Y, Poobalasingam T, Yates LL, Walker SA, Taylor MS, Chessum L, Harrison J, Tsaprouni L, Adcock IM, Lloyd CM, Cookson WO, Moffatt MF, Dean CH.

Dis Model Mech. 2018 Jan 29;11(1). pii: dmm031369. doi: 10.1242/dmm.031369.

18.

The impact of persistent bacterial bronchitis on the pulmonary microbiome of children.

Cuthbertson L, Craven V, Bingle L, Cookson WOCM, Everard ML, Moffatt MF.

PLoS One. 2017 Dec 27;12(12):e0190075. doi: 10.1371/journal.pone.0190075. eCollection 2017.

19.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators, Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, Loth DW, Manichaikul A, Marenholz I, Martinez FJ, Matheson MC, Mathias RA, Matsumoto K, Mbarek H, McArdle WL, Melbye M, Melén E, Meyers D, Michel S, Mohamdi H, Musk AW, Myers RA, Nieuwenhuis MAE, Noguchi E, O'Connor GT, Ogorodova LM, Palmer CD, Palotie A, Park JE, Pennell CE, Pershagen G, Polonikov A, Postma DS, Probst-Hensch N, Puzyrev VP, Raby BA, Raitakari OT, Ramasamy A, Rich SS, Robertson CF, Romieu I, Salam MT, Salomaa V, Schlünssen V, Scott R, Selivanova PA, Sigsgaard T, Simpson A, Siroux V, Smith LJ, Solodilova M, Standl M, Stefansson K, Strachan DP, Stricker BH, Takahashi A, Thompson PJ, Thorleifsson G, Thorsteinsdottir U, Tiesler CMT, Torgerson DG, Tsunoda T, Uitterlinden AG, van der Valk RJP, Vaysse A, Vedantam S, von Berg A, von Mutius E, Vonk JM, Waage J, Wareham NJ, Weiss ST, White WB, Wickman M, Widén E, Willemsen G, Williams LK, Wouters IM, Yang JJ, Zhao JH, Moffatt MF, Ober C, Nicolae DL.

Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22.

20.

Whole-Blood Gene Expression in Pulmonary Nontuberculous Mycobacterial Infection.

Cowman SA, Jacob J, Hansell DM, Kelleher P, Wilson R, Cookson WOC, Moffatt MF, Loebinger MR.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):510-518. doi: 10.1165/rcmb.2017-0230OC.

21.

The lung microbiome in health and disease.

Moffatt MF, Cookson WO.

Clin Med (Lond). 2017 Dec;17(6):525-529. doi: 10.7861/clinmedicine.17-6-525. Review.

22.

New opportunities for managing acute and chronic lung infections.

Cookson WOCM, Cox MJ, Moffatt MF.

Nat Rev Microbiol. 2018 Feb;16(2):111-120. doi: 10.1038/nrmicro.2017.122. Epub 2017 Oct 24. Review.

23.

Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study.

Herazo-Maya JD, Sun J, Molyneaux PL, Li Q, Villalba JA, Tzouvelekis A, Lynn H, Juan-Guardela BM, Risquez C, Osorio JC, Yan X, Michel G, Aurelien N, Lindell KO, Klesen MJ, Moffatt MF, Cookson WO, Zhang Y, Garcia JGN, Noth I, Prasse A, Bar-Joseph Z, Gibson KF, Zhao H, Herzog EL, Rosas IO, Maher TM, Kaminski N.

Lancet Respir Med. 2017 Nov;5(11):857-868. doi: 10.1016/S2213-2600(17)30349-1. Epub 2017 Sep 21.

24.

A novel role for ciliary function in atopy: ADGRV1 and DNAH5 interactions.

Sugier PE, Brossard M, Sarnowski C, Vaysse A, Morin A, Pain L, Margaritte-Jeannin P, Dizier MH, Cookson WOCM, Lathrop M, Moffatt MF, Laprise C, Demenais F, Bouzigon E.

J Allergy Clin Immunol. 2018 May;141(5):1659-1667.e11. doi: 10.1016/j.jaci.2017.06.050. Epub 2017 Sep 18.

25.

Metal worker's lung: spatial association with Mycobacterium avium.

James PL, Cannon J, Barber CM, Crawford L, Hughes H, Jones M, Szram J, Cowman S, Cookson WOC, Moffatt MF, Cullinan P.

Thorax. 2018 Feb;73(2):151-156. doi: 10.1136/thoraxjnl-2017-210226. Epub 2017 Aug 29.

26.

Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA.

Chen J, Behnam E, Huang J, Moffatt MF, Schaid DJ, Liang L, Lin X.

BMC Genomics. 2017 May 26;18(1):413. doi: 10.1186/s12864-017-3808-1.

27.

Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.

Manousaki D, Paternoster L, Standl M, Moffatt MF, Farrall M, Bouzigon E, Strachan DP, Demenais F, Lathrop M, Cookson WOCM, Richards JB.

PLoS Med. 2017 May 9;14(5):e1002294. doi: 10.1371/journal.pmed.1002294. eCollection 2017 May.

28.

Epigenome-wide DNA methylation study of IgE concentration in relation to self-reported allergies.

Ek WE, Ahsan M, Rask-Andersen M, Liang L, Moffatt MF, Gyllensten U, Johansson Å.

Epigenomics. 2017 Apr;9(4):407-418. doi: 10.2217/epi-2016-0158. Epub 2017 Mar 21.

PMID:
28322575
29.

Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium.

Vonk JM, Scholtens S, Postma DS, Moffatt MF, Jarvis D, Ramasamy A, Wjst M, Omenaas ER, Bouzigon E, Demenais F, Nadif R, Siroux V, Polonikov AV, Solodilova M, Ivanov VP, Curjuric I, Imboden M, Kumar A, Probst-Hensch N, Ogorodova LM, Puzyrev VP, Bragina EY, Freidin MB, Nolte IM, Farrall AM, Cookson WO, Strachan DP, Koppelman GH, Boezen HM.

PLoS One. 2017 Mar 2;12(3):e0172716. doi: 10.1371/journal.pone.0172716. eCollection 2017.

30.

Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients.

Cox MJ, Turek EM, Hennessy C, Mirza GK, James PL, Coleman M, Jones A, Wilson R, Bilton D, Cookson WO, Moffatt MF, Loebinger MR.

PLoS One. 2017 Feb 7;12(2):e0170622. doi: 10.1371/journal.pone.0170622. eCollection 2017.

31.

Changes in the respiratory microbiome during acute exacerbations of idiopathic pulmonary fibrosis.

Molyneaux PL, Cox MJ, Wells AU, Kim HC, Ji W, Cookson WO, Moffatt MF, Kim DS, Maher TM.

Respir Res. 2017 Feb 1;18(1):29. doi: 10.1186/s12931-017-0511-3.

32.

Host-Microbial Interactions in Idiopathic Pulmonary Fibrosis.

Molyneaux PL, Willis-Owen SAG, Cox MJ, James P, Cowman S, Loebinger M, Blanchard A, Edwards LM, Stock C, Daccord C, Renzoni EA, Wells AU, Moffatt MF, Cookson WOC, Maher TM.

Am J Respir Crit Care Med. 2017 Jun 15;195(12):1640-1650. doi: 10.1164/rccm.201607-1408OC.

33.

An epigenome-wide association study of total serum IgE in Hispanic children.

Chen W, Wang T, Pino-Yanes M, Forno E, Liang L, Yan Q, Hu D, Weeks DE, Baccarelli A, Acosta-Perez E, Eng C, Han YY, Boutaoui N, Laprise C, Davies GA, Hopkin JM, Moffatt MF, Cookson WOCM, Canino G, Burchard EG, Celedón JC.

J Allergy Clin Immunol. 2017 Aug;140(2):571-577. doi: 10.1016/j.jaci.2016.11.030. Epub 2017 Jan 6.

34.

Global gene regulation during activation of immunoglobulin class switching in human B cells.

Zhang Y, Fear DJ, Willis-Owen SA, Cookson WO, Moffatt MF.

Sci Rep. 2016 Nov 29;6:37988. doi: 10.1038/srep37988.

35.

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro.

Miller S, Henry AP, Hodge E, Kheirallah AK, Billington CK, Rimington TL, Bhaker SK, Obeidat M, Melén E, Merid SK, Swan C, Gowland C, Nelson CP, Stewart CE, Bolton CE, Kilty I, Malarstig A, Parker SG, Moffatt MF, Wardlaw AJ, Hall IP, Sayers I.

PLoS One. 2016 Oct 18;11(10):e0164041. doi: 10.1371/journal.pone.0164041. eCollection 2016.

36.

Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.

Löser S, Gregory LG, Zhang Y, Schaefer K, Walker SA, Buckley J, Denney L, Dean CH, Cookson WOC, Moffatt MF, Lloyd CM.

J Allergy Clin Immunol. 2017 May;139(5):1496-1507.e3. doi: 10.1016/j.jaci.2016.07.033. Epub 2016 Sep 10.

37.

Bacterial microbiota of the upper respiratory tract and childhood asthma.

Depner M, Ege MJ, Cox MJ, Dwyer S, Walker AW, Birzele LT, Genuneit J, Horak E, Braun-Fahrländer C, Danielewicz H, Maier RM, Moffatt MF, Cookson WO, Heederik D, von Mutius E, Legatzki A.

J Allergy Clin Immunol. 2017 Mar;139(3):826-834.e13. doi: 10.1016/j.jaci.2016.05.050. Epub 2016 Jul 27.

PMID:
27576124
38.

LILRA6 copy number variation correlates with susceptibility to atopic dermatitis.

López-Álvarez MR, Jiang W, Jones DC, Jayaraman J, Johnson C, Cookson WO, Moffatt MF, Trowsdale J, Traherne JA.

Immunogenetics. 2016 Oct;68(9):743-7. doi: 10.1007/s00251-016-0924-z. Epub 2016 Jun 22.

39.

Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia.

Fingerlin TE, Zhang W, Yang IV, Ainsworth HC, Russell PH, Blumhagen RZ, Schwarz MI, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch DA, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, du Bois RM, Garcia CK, Devine MS, Gudmundsson G, Isaksson HJ, Kaminski N, Zhang Y, Gibson KF, Lancaster LH, Maher TM, Molyneaux PL, Wells AU, Moffatt MF, Selman M, Pardo A, Kim DS, Crapo JD, Make BJ, Regan EA, Walek DS, Daniel JJ, Kamatani Y, Zelenika D, Murphy E, Smith K, McKean D, Pedersen BS, Talbert J, Powers J, Markin CR, Beckman KB, Lathrop M, Freed B, Langefeld CD, Schwartz DA.

BMC Genet. 2016 Jun 7;17(1):74. doi: 10.1186/s12863-016-0377-2.

40.

A functional AT/G polymorphism in the 5'-untranslated region of SETDB2 in the IgE locus on human chromosome 13q14.

Holt RJ, Vandiedonck C, Willis-Owen SA, Knight JC, Cookson WO, Moffatt MF, Zhang Y.

Genes Immun. 2017 Jan;18(1):57. doi: 10.1038/gene.2016.22. Epub 2016 May 12. No abstract available.

41.

DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis.

Sarnowski C, Laprise C, Malerba G, Moffatt MF, Dizier MH, Morin A, Vincent QB, Rohde K, Esparza-Gordillo J, Margaritte-Jeannin P, Liang L, Lee YA, Bousquet J, Siroux V, Pignatti PF, Cookson WO, Lathrop M, Pastinen T, Demenais F, Bouzigon E.

J Allergy Clin Immunol. 2016 Sep;138(3):748-753. doi: 10.1016/j.jaci.2015.12.1341. Epub 2016 Mar 30.

PMID:
27038909
42.

A functional AT/G polymorphism in the 5'-untranslated region of SETDB2 in the IgE locus on human chromosome 13q14.

Holt RJ, Vandiedonck C, Willis-Owen SA, Knight JC, Cookson WO, Moffatt MF, Zhang Y.

Genes Immun. 2015 Oct;16(7):488-94. doi: 10.1038/gene.2015.36. Epub 2015 Sep 17. Erratum in: Genes Immun. 2017 Jan;18(1):57.

43.

Outside In: Sequencing the Lung Microbiome.

Cox MJ, Moffatt MF, Cookson WO.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):403-4. doi: 10.1164/rccm.201506-1138ED. No abstract available.

44.

Effects of different antibiotic classes on airway bacteria in stable COPD using culture and molecular techniques: a randomised controlled trial.

Brill SE, Law M, El-Emir E, Allinson JP, James P, Maddox V, Donaldson GC, McHugh TD, Cookson WO, Moffatt MF, Nazareth I, Hurst JR, Calverley PM, Sweeting MJ, Wedzicha JA.

Thorax. 2015 Oct;70(10):930-8. doi: 10.1136/thoraxjnl-2015-207194. Epub 2015 Jul 15.

45.

Late-Onset Bloodstream Infection and Perturbed Maturation of the Gastrointestinal Microbiota in Premature Infants.

Shaw AG, Sim K, Randell P, Cox MJ, McClure ZE, Li MS, Donaldson H, Langford PR, Cookson WO, Moffatt MF, Kroll JS.

PLoS One. 2015 Jul 13;10(7):e0132923. doi: 10.1371/journal.pone.0132923. eCollection 2015.

46.

iGWAS: Integrative Genome-Wide Association Studies of Genetic and Genomic Data for Disease Susceptibility Using Mediation Analysis.

Huang YT, Liang L, Moffatt MF, Cookson WO, Lin X.

Genet Epidemiol. 2015 Jul;39(5):347-56. doi: 10.1002/gepi.21905. Epub 2015 May 22.

47.

eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues.

Huang J, Chen J, Esparza J, Ding J, Elder JT, Abecasis GR, Lee YA, Mark Lathrop G, Moffatt MF, Cookson WO, Liang L.

Nat Commun. 2015 May 8;6:6821. doi: 10.1038/ncomms7821.

48.

An epigenome-wide association study of total serum immunoglobulin E concentration.

Liang L, Willis-Owen SAG, Laprise C, Wong KCC, Davies GA, Hudson TJ, Binia A, Hopkin JM, Yang IV, Grundberg E, Busche S, Hudson M, Rönnblom L, Pastinen TM, Schwartz DA, Lathrop GM, Moffatt MF, Cookson WOCM.

Nature. 2015 Apr 30;520(7549):670-674. doi: 10.1038/nature14125. Epub 2015 Feb 18.

49.

Genetic studies of body mass index yield new insights for obesity biology.

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stančáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Chen YI, Clarke R, Daw EW, de Craen AJM, Delgado G, Dimitriou M, Doney ASF, Eklund N, Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V, Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lo KS, Lobbens S, Lorbeer R, Lu Y, Mach F, Magnusson PKE, Mahajan A, McArdle WL, McLachlan S, Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Smith AV, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q; 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Nature. 2015 Feb 12;518(7538):197-206. doi: 10.1038/nature14177.

50.

New genetic loci link adipose and insulin biology to body fat distribution.

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Nature. 2015 Feb 12;518(7538):187-196. doi: 10.1038/nature14132.

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