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Items: 1 to 50 of 174

1.

Asymmetric division yields progeny cells with distinct modes of regulating cell cycle-dependent chromosome methylation.

Zhou X, Wang J, Herrmann J, Moerner WE, Shapiro L.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15661-15670. doi: 10.1073/pnas.1906119116. Epub 2019 Jul 17.

PMID:
31315982
2.

Topologically-guided continuous protein crystallization controls bacterial surface layer self-assembly.

Comerci CJ, Herrmann J, Yoon J, Jabbarpour F, Zhou X, Nomellini JF, Smit J, Shapiro L, Wakatsuki S, Moerner WE.

Nat Commun. 2019 Jun 21;10(1):2731. doi: 10.1038/s41467-019-10650-x.

3.

Viewpoint: Localization Microscopy of Single Molecules Enhanced by 3D Imaging and Light Sheet Illumination.

Moerner WE.

J Phys D Appl Phys. 2019 Jan 2;52(1). pii: 011001. doi: 10.1088/1361-6463/aae632. Epub 2018 Oct 24.

PMID:
31160828
4.

Interferometric Scattering Enables Fluorescence-Free Electrokinetic Trapping of Single Nanoparticles in Free Solution.

Squires AH, Lavania AA, Dahlberg PD, Moerner WE.

Nano Lett. 2019 Jun 12;19(6):4112-4117. doi: 10.1021/acs.nanolett.9b01514. Epub 2019 May 24.

PMID:
31117762
5.

Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx.

Möckl L, Pedram K, Roy AR, Krishnan V, Gustavsson AK, Dorigo O, Bertozzi CR, Moerner WE.

Dev Cell. 2019 Jul 1;50(1):57-72.e6. doi: 10.1016/j.devcel.2019.04.035. Epub 2019 May 16.

PMID:
31105009
6.

Physical Principles of Membrane Shape Regulation by the Glycocalyx.

Shurer CR, Kuo JC, Roberts LM, Gandhi JG, Colville MJ, Enoki TA, Pan H, Su J, Noble JM, Hollander MJ, O'Donnell JP, Yin R, Pedram K, Möckl L, Kourkoutis LF, Moerner WE, Bertozzi CR, Feigenson GW, Reesink HL, Paszek MJ.

Cell. 2019 Jun 13;177(7):1757-1770.e21. doi: 10.1016/j.cell.2019.04.017. Epub 2019 May 2.

PMID:
31056282
7.

Single-molecule trapping and spectroscopy reveals photophysical heterogeneity of phycobilisomes quenched by Orange Carotenoid Protein.

Squires AH, Dahlberg PD, Liu H, Magdaong NCM, Blankenship RE, Moerner WE.

Nat Commun. 2019 Mar 12;10(1):1172. doi: 10.1038/s41467-019-09084-2.

8.

Motional dynamics of single Patched1 molecules in cilia are controlled by Hedgehog and cholesterol.

Weiss LE, Milenkovic L, Yoon J, Stearns T, Moerner WE.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5550-5557. doi: 10.1073/pnas.1816747116. Epub 2019 Feb 28.

9.

Revealing Nanoscale Morphology of the Primary Cilium Using Super-Resolution Fluorescence Microscopy.

Yoon J, Comerci CJ, Weiss LE, Milenkovic L, Stearns T, Moerner WE.

Biophys J. 2019 Jan 22;116(2):319-329. doi: 10.1016/j.bpj.2018.11.3136. Epub 2018 Dec 7.

10.

Identification of PAmKate as a Red Photoactivatable Fluorescent Protein for Cryogenic Super-Resolution Imaging.

Dahlberg PD, Sartor AM, Wang J, Saurabh S, Shapiro L, Moerner WE.

J Am Chem Soc. 2018 Oct 3;140(39):12310-12313. doi: 10.1021/jacs.8b05960. Epub 2018 Sep 20.

PMID:
30222332
11.

Resolving Mixtures in Solution by Single-Molecule Rotational Diffusivity.

Yang HY, Moerner WE.

Nano Lett. 2018 Aug 8;18(8):5279-5287. doi: 10.1021/acs.nanolett.8b02280. Epub 2018 Jul 20.

PMID:
30001492
12.

Light sheet approaches for improved precision in 3D localization-based super-resolution imaging in mammalian cells [Invited].

Gustavsson AK, Petrov PN, Moerner WE.

Opt Express. 2018 May 14;26(10):13122-13147. doi: 10.1364/OE.26.013122. Review.

13.

Tilted Light Sheet Microscopy with 3D Point Spread Functions for Single-Molecule Super-Resolution Imaging in Mammalian Cells.

Gustavsson AK, Petrov PN, Lee MY, Shechtman Y, Moerner WE.

Proc SPIE Int Soc Opt Eng. 2018 Feb;10500. pii: 105000M. doi: 10.1117/12.2288443.

14.

Spatial organization and dynamics of RNase E and ribosomes in Caulobacter crescentus.

Bayas CA, Wang J, Lee MK, Schrader JM, Shapiro L, Moerner WE.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3712-E3721. doi: 10.1073/pnas.1721648115. Epub 2018 Apr 2.

15.

Single-molecule diffusometry reveals the nucleotide-dependent oligomerization pathways of Nicotiana tabacum Rubisco activase.

Wang Q, Serban AJ, Wachter RM, Moerner WE.

J Chem Phys. 2018 Mar 28;148(12):123319. doi: 10.1063/1.5005930.

PMID:
29604852
16.

3D single-molecule super-resolution microscopy with a tilted light sheet.

Gustavsson AK, Petrov PN, Lee MY, Shechtman Y, Moerner WE.

Nat Commun. 2018 Jan 9;9(1):123. doi: 10.1038/s41467-017-02563-4.

17.

Observation of live chromatin dynamics in cells via 3D localization microscopy using Tetrapod point spread functions.

Shechtman Y, Gustavsson AK, Petrov PN, Dultz E, Lee MY, Weis K, Moerner WE.

Biomed Opt Express. 2017 Nov 21;8(12):5735-5748. doi: 10.1364/BOE.8.005735. eCollection 2017 Dec 1.

18.

Single-Molecule Imaging of Wnt3A Protein Diffusion on Living Cell Membranes.

Lippert A, Janeczek AA, Fürstenberg A, Ponjavic A, Moerner WE, Nusse R, Helms JA, Evans ND, Lee SF.

Biophys J. 2017 Dec 19;113(12):2762-2767. doi: 10.1016/j.bpj.2017.08.060.

19.

Direct single-molecule measurements of phycocyanobilin photophysics in monomeric C-phycocyanin.

Squires AH, Moerner WE.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9779-9784. doi: 10.1073/pnas.1705435114. Epub 2017 Aug 28.

20.

Super-Resolution Microscopy and Single-Protein Tracking in Live Bacteria Using a Genetically Encoded, Photostable Fluoromodule.

Saurabh S, Perez AM, Comerci CJ, Shapiro L, Moerner WE.

Curr Protoc Cell Biol. 2017 Jun 19;75:4.32.1-4.32.22. doi: 10.1002/cpcb.21.

21.

Measurement-based estimation of global pupil functions in 3D localization microscopy.

Petrov PN, Shechtman Y, Moerner WE.

Opt Express. 2017 Apr 3;25(7):7945-7959. doi: 10.1364/OE.25.007945.

22.

Three-Dimensional Localization of Single Molecules for Super-Resolution Imaging and Single-Particle Tracking.

von Diezmann A, Shechtman Y, Moerner WE.

Chem Rev. 2017 Jun 14;117(11):7244-7275. doi: 10.1021/acs.chemrev.6b00629. Epub 2017 Feb 2. Review.

23.
24.

Removing Orientation-Induced Localization Biases in Single-Molecule Microscopy Using a Broadband Metasurface Mask.

Backlund MP, Arbabi A, Petrov PN, Arbabi E, Saurabh S, Faraon A, Moerner WE.

Nat Photonics. 2016;10:459-462. Epub 2016 May 16.

25.

Super-resolution Imaging of Live Bacteria Cells Using a Genetically Directed, Highly Photostable Fluoromodule.

Saurabh S, Perez AM, Comerci CJ, Shapiro L, Moerner WE.

J Am Chem Soc. 2016 Aug 24;138(33):10398-401. doi: 10.1021/jacs.6b05943. Epub 2016 Aug 10.

26.

Correcting field-dependent aberrations with nanoscale accuracy in three-dimensional single-molecule localization microscopy.

von Diezmann A, Lee MY, Lew MD, Moerner WE.

Optica. 2015 Nov 20;2(11):985-993. Epub 2015 Nov 19.

27.

Multicolour localization microscopy by point-spread-function engineering.

Shechtman Y, Weiss LE, Backer AS, Lee MY, Moerner WE.

Nat Photonics. 2016;10:590-594. doi: 10.1038/nphoton.2016.137. Epub 2016 Aug 8.

28.

Single-molecule spectroscopy and imaging over the decades.

Moerner WE, Shechtman Y, Wang Q.

Faraday Discuss. 2015;184:9-36. doi: 10.1039/c5fd00149h. Epub 2015 Nov 30. Review.

29.

Dissecting pigment architecture of individual photosynthetic antenna complexes in solution.

Wang Q, Moerner WE.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13880-5. doi: 10.1073/pnas.1514027112. Epub 2015 Oct 5.

30.

Delayed emergence of subdiffraction-sized mutant huntingtin fibrils following inclusion body formation.

Sahl SJ, Lau L, Vonk WI, Weiss LE, Frydman J, Moerner WE.

Q Rev Biophys. 2016 Jan;49:e2. Epub 2015 Sep 9.

31.

Single-Molecule Identification of Quenched and Unquenched States of LHCII.

Schlau-Cohen GS, Yang HY, Krüger TP, Xu P, Gwizdala M, van Grondelle R, Croce R, Moerner WE.

J Phys Chem Lett. 2015 Mar 5;6(5):860-7. doi: 10.1021/acs.jpclett.5b00034. Epub 2015 Feb 23.

PMID:
26262664
32.

Chromosomal locus tracking with proper accounting of static and dynamic errors.

Backlund MP, Joyner R, Moerner WE.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Jun;91(6):062716. Epub 2015 Jun 29.

33.

Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1.

Milenkovic L, Weiss LE, Yoon J, Roth TL, Su YS, Sahl SJ, Scott MP, Moerner WE.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8320-5. doi: 10.1073/pnas.1510094112. Epub 2015 Jun 22.

34.

Single-Molecule Spectroscopy, Imaging, and Photocontrol: Foundations for Super-Resolution Microscopy (Nobel Lecture).

Moerner WE.

Angew Chem Int Ed Engl. 2015 Jul 6;54(28):8067-93. doi: 10.1002/anie.201501949. Epub 2015 Jun 18.

PMID:
26088273
35.

Precise Three-Dimensional Scan-Free Multiple-Particle Tracking over Large Axial Ranges with Tetrapod Point Spread Functions.

Shechtman Y, Weiss LE, Backer AS, Sahl SJ, Moerner WE.

Nano Lett. 2015 Jun 10;15(6):4194-9. doi: 10.1021/acs.nanolett.5b01396. Epub 2015 May 18.

36.

Determining the rotational mobility of a single molecule from a single image: a numerical study.

Backer AS, Moerner WE.

Opt Express. 2015 Feb 23;23(4):4255-76. doi: 10.1364/OE.23.004255.

37.

Robust hypothesis tests for detecting statistical evidence of two-dimensional and three-dimensional interactions in single-molecule measurements.

Calderon CP, Weiss LE, Moerner WE.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 May;89(5):052705. Epub 2014 May 12.

PMID:
25353827
38.

Super-resolution fluorescence of huntingtin reveals growth of globular species into short fibers and coexistence of distinct aggregates.

Duim WC, Jiang Y, Shen K, Frydman J, Moerner WE.

ACS Chem Biol. 2014 Dec 19;9(12):2767-78. doi: 10.1021/cb500335w. Epub 2014 Oct 20.

39.

Correlations of three-dimensional motion of chromosomal loci in yeast revealed by the double-helix point spread function microscope.

Backlund MP, Joyner R, Weis K, Moerner WE.

Mol Biol Cell. 2014 Nov 5;25(22):3619-29. doi: 10.1091/mbc.E14-06-1127. Epub 2014 Oct 15.

40.

The regulatory switch of F1-ATPase studied by single-molecule FRET in the ABEL Trap.

Bockenhauer SD, Duncan TM, Moerner WE, Börsch M.

Proc SPIE Int Soc Opt Eng. 2014 Apr 1;8950:89500H.

41.

Optimal point spread function design for 3D imaging.

Shechtman Y, Sahl SJ, Backer AS, Moerner WE.

Phys Rev Lett. 2014 Sep 26;113(13):133902. Epub 2014 Sep 26.

42.

Azimuthal polarization filtering for accurate, precise, and robust single-molecule localization microscopy.

Lew MD, Moerner WE.

Nano Lett. 2014 Nov 12;14(11):6407-13. doi: 10.1021/nl502914k. Epub 2014 Oct 16.

43.

Small-molecule labeling of live cell surfaces for three-dimensional super-resolution microscopy.

Lee MK, Rai P, Williams J, Twieg RJ, Moerner WE.

J Am Chem Soc. 2014 Oct 8;136(40):14003-6. doi: 10.1021/ja508028h. Epub 2014 Sep 24.

44.

Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function.

Lee YL, Santé J, Comerci CJ, Cyge B, Menezes LF, Li FQ, Germino GG, Moerner WE, Takemaru K, Stearns T.

Mol Biol Cell. 2014 Oct 1;25(19):2919-33. doi: 10.1091/mbc.E14-02-0735. Epub 2014 Aug 7.

45.

A bisected pupil for studying single-molecule orientational dynamics and its application to three-dimensional super-resolution microscopy.

Backer AS, Backlund MP, von Diezmann AR, Sahl SJ, Moerner WE.

Appl Phys Lett. 2014 May 12;104(19):193701.

46.

Bacterial scaffold directs pole-specific centromere segregation.

Ptacin JL, Gahlmann A, Bowman GR, Perez AM, von Diezmann AR, Eckart MR, Moerner WE, Shapiro L.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):E2046-55. doi: 10.1073/pnas.1405188111. Epub 2014 Apr 28.

47.

Extending single-molecule microscopy using optical Fourier processing.

Backer AS, Moerner WE.

J Phys Chem B. 2014 Jul 17;118(28):8313-29. doi: 10.1021/jp501778z. Epub 2014 May 12.

48.

Single-molecule motions enable direct visualization of biomolecular interactions in solution.

Wang Q, Moerner WE.

Nat Methods. 2014 May;11(5):555-8. doi: 10.1038/nmeth.2882. Epub 2014 Mar 9.

PMID:
24608179
49.

From "There's Plenty of Room at the Bottom" to seeing what is actually there.

Fitzpatrick JA, Inouye Y, Manley S, Moerner WE.

Chemphyschem. 2014 Mar 17;15(4):547-9. doi: 10.1002/cphc.201400097. Epub 2014 Mar 3. No abstract available.

PMID:
24590957
50.

The role of molecular dipole orientation in single-molecule fluorescence microscopy and implications for super-resolution imaging.

Backlund MP, Lew MD, Backer AS, Sahl SJ, Moerner WE.

Chemphyschem. 2014 Mar 17;15(4):587-99. doi: 10.1002/cphc.201300880. Epub 2013 Dec 30. Review.

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