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Items: 1 to 50 of 218

1.

What viruses tell us about evolution and immunity: beyond Darwin?

Broecker F, Moelling K.

Ann N Y Acad Sci. 2019 Jul;1447(1):53-68. doi: 10.1111/nyas.14097. Epub 2019 Apr 29.

PMID:
31032941
2.

Viruses and Evolution - Viruses First? A Personal Perspective.

Moelling K, Broecker F.

Front Microbiol. 2019 Mar 19;10:523. doi: 10.3389/fmicb.2019.00523. eCollection 2019.

3.

Evolution of Immune Systems From Viruses and Transposable Elements.

Broecker F, Moelling K.

Front Microbiol. 2019 Jan 29;10:51. doi: 10.3389/fmicb.2019.00051. eCollection 2019. Review.

4.

A Wake-Up Call: We Need Phage Therapy Now.

Moelling K, Broecker F, Willy C.

Viruses. 2018 Dec 5;10(12). pii: E688. doi: 10.3390/v10120688. Review.

5.

On the occasion of the retirement of Marc Regenmortel as Editor-in-Chief of Archives of Virology.

Moelling K.

Arch Virol. 2018 Sep;163(9):2311. doi: 10.1007/s00705-018-3981-9. Epub 2018 Aug 13. No abstract available.

PMID:
30105519
6.

Commentary to: Cause of Cambrian explosion - Terrestrial or cosmic? Steele, E.J. et al.

Moelling K.

Prog Biophys Mol Biol. 2018 Aug;136:24. doi: 10.1016/j.pbiomolbio.2018.03.005. Epub 2018 Mar 21. No abstract available.

PMID:
29571770
7.

RNase H As Gene Modifier, Driver of Evolution and Antiviral Defense.

Moelling K, Broecker F, Russo G, Sunagawa S.

Front Microbiol. 2017 Sep 14;8:1745. doi: 10.3389/fmicb.2017.01745. eCollection 2017. Review.

8.

Fecal microbiota transplantation to fight Clostridium difficile infections and other intestinal diseases.

Moelling K, Broecker F.

Bacteriophage. 2016 Oct 21;6(4):e1251380. doi: 10.1080/21597081.2016.1251380. eCollection 2016.

9.

The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation.

Broecker F, Horton R, Heinrich J, Franz A, Schweiger MR, Lehrach H, Moelling K.

Mob DNA. 2016 Dec 7;7:25. eCollection 2016.

10.

Stable core virome despite variable microbiome after fecal transfer.

Broecker F, Russo G, Klumpp J, Moelling K.

Gut Microbes. 2017 May 4;8(3):214-220. doi: 10.1080/19490976.2016.1265196. Epub 2016 Dec 9. Review.

11.

Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex-forming oligonucleotide.

Voges M, Schneider C, Sinn M, Hartig JS, Reimer R, Hauber J, Moelling K.

BMC Infect Dis. 2016 Jul 22;16:358. doi: 10.1186/s12879-016-1713-x.

12.

Long-term microbiota and virome in a Zürich patient after fecal transplantation against Clostridium difficile infection.

Broecker F, Klumpp J, Moelling K.

Ann N Y Acad Sci. 2016 May;1372(1):29-41. doi: 10.1111/nyas.13100. Epub 2016 Jun 10.

PMID:
27286042
13.

Nutrition and the microbiome.

Moelling K.

Ann N Y Acad Sci. 2016 May;1372(1):3-8. doi: 10.1111/nyas.13039. Epub 2016 Jun 10. No abstract available.

PMID:
27285591
14.

Long-term changes of bacterial and viral compositions in the intestine of a recovered Clostridium difficile patient after fecal microbiota transplantation.

Broecker F, Klumpp J, Schuppler M, Russo G, Biedermann L, Hombach M, Rogler G, Moelling K.

Cold Spring Harb Mol Case Stud. 2016 Jan;2(1):a000448. doi: 10.1101/mcs.a000448.

15.

Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line.

Broecker F, Hardt C, Herwig R, Timmermann B, Kerick M, Wunderlich A, Schweiger MR, Borsig L, Heikenwalder M, Lehrach H, Moelling K.

FEBS J. 2016 May;283(9):1669-88. doi: 10.1111/febs.13694. Epub 2016 Mar 25.

16.

The reverse transcriptase-RNase H: from viruses to antiviral defense.

Moelling K, Broecker F.

Ann N Y Acad Sci. 2015 Apr;1341:126-35. doi: 10.1111/nyas.12668. Epub 2015 Feb 19. Review.

PMID:
25703292
17.

Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions.

Vargas C, Radziwill G, Krause G, Diehl A, Keller S, Kamdem N, Czekelius C, Kreuchwig A, Schmieder P, Doyle D, Moelling K, Hagen V, Schade M, Oschkinat H.

ChemMedChem. 2014 Jul;9(7):1458-62. doi: 10.1002/cmdc.201300553. Epub 2014 Mar 25.

PMID:
24668962
18.

Analysis of the intestinal microbiome of a recovered Clostridium difficile patient after fecal transplantation.

Broecker F, Kube M, Klumpp J, Schuppler M, Biedermann L, Hecht J, Hombach M, Keller PM, Rogler G, Moelling K.

Digestion. 2013;88(4):243-51. doi: 10.1159/000355955. Epub 2013 Dec 5.

19.

RNase H: specificity, mechanisms of action, and antiviral target.

Moelling K, Broecker F, Kerrigan JE.

Methods Mol Biol. 2014;1087:71-84. doi: 10.1007/978-1-62703-670-2_7.

PMID:
24158815
20.

Photodynamic agents with anti-metastatic activities.

Vummidi BR, Noreen F, Alzeer J, Moelling K, Luedtke NW.

ACS Chem Biol. 2013 Aug 16;8(8):1737-46. doi: 10.1021/cb400008t. Epub 2013 May 28.

PMID:
23672401
21.

What contemporary viruses tell us about evolution: a personal view.

Moelling K.

Arch Virol. 2013 Sep;158(9):1833-48. doi: 10.1007/s00705-013-1679-6. Epub 2013 Apr 9. Review.

22.

MRSA transmission on a neonatal intensive care unit: epidemiological and genome-based phylogenetic analyses.

Nübel U, Nachtnebel M, Falkenhorst G, Benzler J, Hecht J, Kube M, Bröcker F, Moelling K, Bührer C, Gastmeier P, Piening B, Behnke M, Dehnert M, Layer F, Witte W, Eckmanns T.

PLoS One. 2013;8(1):e54898. doi: 10.1371/journal.pone.0054898. Epub 2013 Jan 31.

23.

Are viruses our oldest ancestors?

Moelling K.

EMBO Rep. 2012 Dec;13(12):1033. doi: 10.1038/embor.2012.173. Epub 2012 Nov 13. No abstract available.

24.

Premature activation of the HIV RNase H drives the virus into suicide: a novel microbicide?

Broecker F, Andrae K, Moelling K.

AIDS Res Hum Retroviruses. 2012 Nov;28(11):1397-403. doi: 10.1089/aid.2012.0067. Epub 2012 Aug 29. Review.

PMID:
22931114
25.

Short hairpin-looped oligodeoxynucleotides reduce hepatitis C virus replication.

Broecker F, Moelling K.

Virol J. 2012 Jul 23;9:134. doi: 10.1186/1743-422X-9-134.

26.

Targeting the retroviral ribonuclease H by rational drug design.

Moelling K.

AIDS. 2012 Oct 23;26(16):1983-93. doi: 10.1097/QAD.0b013e32835537d3. Review.

PMID:
22555171
27.
28.

A short hairpin DNA analogous to miR-125b inhibits C-Raf expression, proliferation, and survival of breast cancer cells.

Hofmann MH, Heinrich J, Radziwill G, Moelling K.

Mol Cancer Res. 2009 Oct;7(10):1635-44. doi: 10.1158/1541-7786.MCR-09-0043. Epub 2009 Oct 13. Erratum in: Mol Cancer Res. 2010 Jun;8(6):935. Radziwil, Gerald [corrected to Radziwill, Gerald].

29.

The PDZ protein MPP2 interacts with c-Src in epithelial cells.

Baumgartner M, Weiss A, Fritzius T, Heinrich J, Moelling K.

Exp Cell Res. 2009 Oct 15;315(17):2888-98. doi: 10.1016/j.yexcr.2009.07.028. Epub 2009 Aug 6.

PMID:
19665017
30.

Reduction of gene expression by a hairpin-loop structured oligodeoxynucleotide: alternative to siRNA and antisense.

Kwok T, Heinrich J, Jung-Shiu J, Meier MG, Mathur S, Moelling K.

Biochim Biophys Acta. 2009 Oct;1790(10):1170-8. doi: 10.1016/j.bbagen.2009.05.017. Epub 2009 Jun 6.

PMID:
19505533
31.

Antitumor activity of small double-stranded oligodeoxynucleotides targeting telomerase RNA in malignant melanoma cells.

Noreen F, Heinrich J, Moelling K.

Oligonucleotides. 2009 Jun;19(2):169-78. doi: 10.1089/oli.2008.0170.

PMID:
19441892
32.

Short hairpin-loop-structured oligodeoxynucleotides reduce HSV-1 replication.

Falkenhagen A, Heinrich J, Moelling K.

Virol J. 2009 Apr 27;6:43. doi: 10.1186/1743-422X-6-43.

33.

Retroviral self-inactivation in the mouse vagina induced by short DNA.

Wittmer-Elzaouk L, Jung-Shiu J, Heinrich J, Moelling K.

Antiviral Res. 2009 Apr;82(1):22-8. doi: 10.1016/j.antiviral.2009.01.002. Epub 2009 Feb 2.

PMID:
19189851
34.

Vero cells as a model to study the effects of adenoviral gene delivery vectors on the RNAi system in context of viral infection.

Matskevich AA, Jung JS, Schümann M, Cascallo M, Moelling K.

J Innate Immun. 2009;1(4):389-94. doi: 10.1159/000191408. Epub 2009 Jan 8.

35.

Oligonucleotide-mediated retroviral RNase H activation leads to reduced HIV-1 titer in patient-derived plasma.

Heinrich J, Mathur S, Matskevich AA, Moelling K.

AIDS. 2009 Jan 14;23(2):213-21. doi: 10.1097/QAD.0b013e32831c5480.

PMID:
19098491
36.

Inhibition of influenza A virus replication by short double-stranded oligodeoxynucleotides.

Kwok T, Helfer H, Alam MI, Heinrich J, Pavlovic J, Moelling K.

Arch Virol. 2009;154(1):109-14. doi: 10.1007/s00705-008-0262-z. Epub 2008 Nov 26.

PMID:
19034603
37.

The PDZ protein erbin modulates beta-catenin-dependent transcription.

Ress A, Moelling K.

Eur Surg Res. 2008;41(3):284-9. doi: 10.1159/000148241. Epub 2008 Jul 30.

PMID:
18667832
38.

Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis.

Fritzius T, Moelling K.

EMBO J. 2008 May 7;27(9):1399-410. doi: 10.1038/emboj.2008.67. Epub 2008 Apr 3.

39.

Stimuli-dependent cleavage of Dicer during apoptosis.

Matskevich AA, Moelling K.

Biochem J. 2008 Jun 15;412(3):527-34. doi: 10.1042/BJ20071461.

PMID:
18289125
40.

c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site.

Baumgartner M, Radziwill G, Lorger M, Weiss A, Moelling K.

Mol Cell Biol. 2008 Jan;28(2):642-55. Epub 2007 Nov 26.

41.

Characterization of a putative phosphorylation switch: adaptation of SPOT synthesis to analyze PDZ domain regulation mechanisms.

Boisguerin P, Ay B, Radziwill G, Fritz RD, Moelling K, Volkmer R.

Chembiochem. 2007 Dec 17;8(18):2302-7.

PMID:
17973281
42.

Role of AF6 protein in cell-to-cell spread of Herpes simplex virus 1.

Keyser J, Lorger M, Pavlovic J, Radziwill G, Moelling K.

FEBS Lett. 2007 Nov 27;581(28):5349-54. Epub 2007 Oct 29.

43.

c-Src is a PDZ interaction partner and substrate of the E3 ubiquitin ligase Ligand-of-Numb protein X1.

Weiss A, Baumgartner M, Radziwill G, Dennler J, Moelling K.

FEBS Lett. 2007 Oct 30;581(26):5131-6. Epub 2007 Oct 8.

44.

Dicer is involved in protection against influenza A virus infection.

Matskevich AA, Moelling K.

J Gen Virol. 2007 Oct;88(Pt 10):2627-35.

PMID:
17872512
45.

Heteromeric complex formation of ASK2 and ASK1 regulates stress-induced signaling.

Ortner E, Moelling K.

Biochem Biophys Res Commun. 2007 Oct 19;362(2):454-9. Epub 2007 Aug 10.

PMID:
17714688
46.
47.

RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides.

Matzen K, Elzaouk L, Matskevich AA, Nitzsche A, Heinrich J, Moelling K.

Nat Biotechnol. 2007 Jun;25(6):669-74. Epub 2007 Jun 3.

PMID:
17546028
48.

Regulation of c-Src by binding to the PDZ domain of AF-6.

Radziwill G, Weiss A, Heinrich J, Baumgartner M, Boisguerin P, Owada K, Moelling K.

EMBO J. 2007 Jun 6;26(11):2633-44. Epub 2007 May 10.

49.

Relationship between retroviral replication and RNA interference machineries.

Moelling K, Matskevich A, Jung JS.

Cold Spring Harb Symp Quant Biol. 2006;71:365-8. Review.

PMID:
17381318
50.

WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.

Fritzius T, Frey AD, Schweneker M, Mayer D, Moelling K.

FEBS J. 2007 Mar;274(6):1552-66.

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