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Items: 1 to 50 of 96

1.

Cre recombinase toxicity in podocytes, a novel genetic model for FSGS in adolescent mice.

Frahsek M, Schulte K, Chia-Gil A, Djudjaj S, Schueler H, Leuchtle K, Smeets B, Dijkman H, Floege J, Moeller MJ.

Am J Physiol Renal Physiol. 2019 Oct 7. doi: 10.1152/ajprenal.00573.2018. [Epub ahead of print]

PMID:
31588799
2.

mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans.

Puelles VG, van der Wolde JW, Wanner N, Scheppach MW, Cullen-McEwen LA, Bork T, Lindenmeyer MT, Gernhold L, Wong MN, Braun F, Cohen CD, Kett MM, Kuppe C, Kramann R, Saritas T, van Roeyen CR, Moeller MJ, Tribolet L, Rebello R, Sun YB, Li J, Müller-Newen G, Hughson MD, Hoy WE, Person F, Wiech T, Ricardo SD, Kerr PG, Denton KM, Furic L, Huber TB, Nikolic-Paterson DJ, Bertram JF.

JCI Insight. 2019 Sep 19;4(18). pii: 99271. doi: 10.1172/jci.insight.99271.

3.

Cellular regeneration of podocytes from parietal cells: the debate is still open.

Moeller MJ, Tharaux PL.

Kidney Int. 2019 Sep;96(3):542-544. doi: 10.1016/j.kint.2019.04.038.

PMID:
31445579
4.

The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression.

Lazareth H, Henique C, Lenoir O, Puelles VG, Flamant M, Bollée G, Fligny C, Camus M, Guyonnet L, Millien C, Gaillard F, Chipont A, Robin B, Fabrega S, Dhaun N, Camerer E, Kretz O, Grahammer F, Braun F, Huber TB, Nochy D, Mandet C, Bruneval P, Mesnard L, Thervet E, Karras A, Le Naour F, Rubinstein E, Boucheix C, Alexandrou A, Moeller MJ, Bouzigues C, Tharaux PL.

Nat Commun. 2019 Jul 24;10(1):3303. doi: 10.1038/s41467-019-11013-2.

5.

Postnatal podocyte gain: Is the jury still out?

Puelles VG, Moeller MJ.

Semin Cell Dev Biol. 2019 Jul;91:147-152. doi: 10.1016/j.semcdb.2018.07.007. Epub 2018 Jul 12. Review.

PMID:
31178004
6.

Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.

Puelles VG, Fleck D, Ortz L, Papadouri S, Strieder T, Böhner AMC, van der Wolde JW, Vogt M, Saritas T, Kuppe C, Fuss A, Menzel S, Klinkhammer BM, Müller-Newen G, Heymann F, Decker L, Braun F, Kretz O, Huber TB, Susaki EA, Ueda HR, Boor P, Floege J, Kramann R, Kurts C, Bertram JF, Spehr M, Nikolic-Paterson DJ, Moeller MJ.

Kidney Int. 2019 Aug;96(2):505-516. doi: 10.1016/j.kint.2019.02.034. Epub 2019 Mar 15.

7.

Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions.

Kuppe C, Leuchtle K, Wagner A, Kabgani N, Saritas T, Puelles VG, Smeets B, Hakroush S, van der Vlag J, Boor P, Schiffer M, Gröne HJ, Fogo A, Floege J, Moeller MJ.

Kidney Int. 2019 Jul;96(1):80-93. doi: 10.1016/j.kint.2019.01.037. Epub 2019 Feb 27.

8.

DDR1 role in fibrosis and its pharmacological targeting.

Moll S, Desmoulière A, Moeller MJ, Pache JC, Badi L, Arcadu F, Richter H, Satz A, Uhles S, Cavalli A, Drawnel F, Scapozza L, Prunotto M.

Biochim Biophys Acta Mol Cell Res. 2019 Nov;1866(11):118474. doi: 10.1016/j.bbamcr.2019.04.004. Epub 2019 Apr 5. Review.

PMID:
30954571
9.

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.

Saritas T, Cuevas CA, Ferdaus MZ, Kuppe C, Kramann R, Moeller MJ, Floege J, Singer JD, McCormick JA.

Sci Rep. 2019 Mar 14;9(1):4596. doi: 10.1038/s41598-019-40795-0.

10.

Management and treatment of glomerular diseases (part 2): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Rovin BH, Caster DJ, Cattran DC, Gibson KL, Hogan JJ, Moeller MJ, Roccatello D, Cheung M, Wheeler DC, Winkelmayer WC, Floege J; Conference Participants.

Kidney Int. 2019 Feb;95(2):281-295. doi: 10.1016/j.kint.2018.11.008.

11.

[What is certain in the treatment of glomerulonephritis?]

Floege J, Boor P, Moeller MJ.

Internist (Berl). 2018 Dec;59(12):1268-1278. doi: 10.1007/s00108-018-0500-8. Review. German.

PMID:
30250965
12.

Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime.

Moll S, Yasui Y, Abed A, Murata T, Shimada H, Maeda A, Fukushima N, Kanamori M, Uhles S, Badi L, Cagarelli T, Formentini I, Drawnel F, Georges G, Bergauer T, Gasser R, Bonfil RD, Fridman R, Richter H, Funk J, Moeller MJ, Chatziantoniou C, Prunotto M.

J Transl Med. 2018 Jun 1;16(1):148. doi: 10.1186/s12967-018-1524-5.

13.

Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressures.

Kuppe C, Rohlfs W, Grepl M, Schulte K, Veron D, Elger M, Sanden SK, Saritas T, Andrae J, Betsholtz C, Trautwein C, Hausmann R, Quaggin S, Bachmann S, Kriz W, Tufro A, Floege J, Moeller MJ.

Nephrol Dial Transplant. 2018 Sep 1;33(9):1514-1525. doi: 10.1093/ndt/gfy057.

14.

The transcription factor Dach1 is essential for podocyte function.

Endlich N, Kliewe F, Kindt F, Schmidt K, Kotb AM, Artelt N, Lindenmeyer MT, Cohen CD, Döring F, Kuss AW, Amann K, Moeller MJ, Kabgani N, Blumenthal A, Endlich K.

J Cell Mol Med. 2018 May;22(5):2656-2669. doi: 10.1111/jcmm.13544. Epub 2018 Mar 2.

15.

CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis.

Eymael J, Sharma S, Loeven MA, Wetzels JF, Mooren F, Florquin S, Deegens JK, Willemsen BK, Sharma V, van Kuppevelt TH, Bakker MA, Ostendorf T, Moeller MJ, Dijkman HB, Smeets B, van der Vlag J.

Kidney Int. 2018 Mar;93(3):626-642. doi: 10.1016/j.kint.2017.09.020. Epub 2017 Dec 21.

PMID:
29276101
16.

Retinoic acid improves nephrotoxic serum-induced glomerulonephritis through activation of podocyte retinoic acid receptor α.

Dai Y, Chen A, Liu R, Gu L, Sharma S, Cai W, Salem F, Salant DJ, Pippin JW, Shankland SJ, Moeller MJ, Ghyselinck NB, Ding X, Chuang PY, Lee K, He JC.

Kidney Int. 2017 Dec;92(6):1444-1457. doi: 10.1016/j.kint.2017.04.026. Epub 2017 Jul 27.

17.

Quantifying podocyte depletion: theoretical and practical considerations.

Puelles VG, Bertram JF, Moeller MJ.

Cell Tissue Res. 2017 Jul;369(1):229-236. doi: 10.1007/s00441-017-2630-z. Epub 2017 May 30. Review.

PMID:
28560693
18.

We can see clearly now: optical clearing and kidney morphometrics.

Puelles VG, Moeller MJ, Bertram JF.

Curr Opin Nephrol Hypertens. 2017 May;26(3):179-186. doi: 10.1097/MNH.0000000000000314. Review.

PMID:
28198736
19.

Investigations of Glucocorticoid Action in GN.

Kuppe C, van Roeyen C, Leuchtle K, Kabgani N, Vogt M, Van Zandvoort M, Smeets B, Floege J, Gröne HJ, Moeller MJ.

J Am Soc Nephrol. 2017 May;28(5):1408-1420. doi: 10.1681/ASN.2016010060. Epub 2016 Nov 28.

20.

Minimal change disease and idiopathic FSGS: manifestations of the same disease.

Maas RJ, Deegens JK, Smeets B, Moeller MJ, Wetzels JF.

Nat Rev Nephrol. 2016 Dec;12(12):768-776. doi: 10.1038/nrneph.2016.147. Epub 2016 Oct 17. Review.

PMID:
27748392
21.

Focal segmental glomerulosclerosis: it may no longer be all about podocytes.

Kuppe C, Moeller MJ.

Kidney Int. 2016 Oct;90(4):905. doi: 10.1016/j.kint.2016.07.025. No abstract available.

PMID:
27633870
22.

The Authors Reply.

Kuppe C, Moeller MJ.

Kidney Int. 2016 Jun;89(6):1404. doi: 10.1016/j.kint.2016.03.002. No abstract available.

PMID:
27181785
23.

Underestimated associated features in CMT neuropathies: clinical indicators for the causative gene?

Werheid F, Azzedine H, Zwerenz E, Bozkurt A, Moeller MJ, Lin L, Mull M, Häusler M, Schulz JB, Weis J, Claeys KG.

Brain Behav. 2016 Mar 4;6(4):e00451. doi: 10.1002/brb3.451. eCollection 2016 Apr.

24.

The atypical cadherin Dachsous1 localizes to the base of the ciliary apparatus in airway epithelia.

Dau C, Fliegauf M, Omran H, Schlensog M, Dahl E, van Roeyen CR, Kriz W, Moeller MJ, Braun GS.

Biochem Biophys Res Commun. 2016 May 13;473(4):1177-1184. doi: 10.1016/j.bbrc.2016.04.036. Epub 2016 Apr 10.

PMID:
27074579
25.

Interaction of atypical cadherin Fat1 with SoHo adaptor proteins CAP/ponsin and ArgBP2.

Braun GS, Kuszka A, Dau C, Kriz W, Moeller MJ.

Biochem Biophys Res Commun. 2016 Mar 25;472(1):88-94. doi: 10.1016/j.bbrc.2016.02.069. Epub 2016 Feb 19.

PMID:
26903299
26.

Glomerulonephritis triggered by a chronically infected left ventricular assist device.

Saritas T, Brandenburg V, Federico G, Gröne HJ, Floege J, Moeller MJ, Moza A.

Lancet. 2015 Dec 5;386(10010):2363-4. doi: 10.1016/S0140-6736(15)00822-3. No abstract available.

PMID:
26681291
27.

Isolation and Primary Culture of Murine Podocytes with Proven Origin.

Smeets B, Kabgani N, Moeller MJ.

Methods Mol Biol. 2016;1397:3-10. doi: 10.1007/978-1-4939-3353-2_1.

PMID:
26676122
28.

Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74.

Djudjaj S, Lue H, Rong S, Papasotiriou M, Klinkhammer BM, Zok S, Klaener O, Braun GS, Lindenmeyer MT, Cohen CD, Bucala R, Tittel AP, Kurts C, Moeller MJ, Floege J, Ostendorf T, Bernhagen J, Boor P.

J Am Soc Nephrol. 2016 Jun;27(6):1650-64. doi: 10.1681/ASN.2015020149. Epub 2015 Oct 9.

29.

The lymphotoxin β receptor is a potential therapeutic target in renal inflammation.

Seleznik G, Seeger H, Bauer J, Fu K, Czerkowicz J, Papandile A, Poreci U, Rabah D, Ranger A, Cohen CD, Lindenmeyer M, Chen J, Edenhofer I, Anders HJ, Lech M, Wüthrich RP, Ruddle NH, Moeller MJ, Kozakowski N, Regele H, Browning JL, Heikenwalder M, Segerer S.

Kidney Int. 2016 Jan;89(1):113-26. doi: 10.1038/ki.2015.280. Epub 2016 Jan 4.

PMID:
26398497
30.

Progress and controversies in unraveling the glomerular filtration mechanism.

Saritas T, Kuppe C, Moeller MJ.

Curr Opin Nephrol Hypertens. 2015 May;24(3):208-16. doi: 10.1097/MNH.0000000000000116. Review.

PMID:
25887902
31.

Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis.

Kuppe C, Gröne HJ, Ostendorf T, van Kuppevelt TH, Boor P, Floege J, Smeets B, Moeller MJ.

Kidney Int. 2015 Nov;88(5):990-8. doi: 10.1038/ki.2015.116. Epub 2015 Apr 8.

PMID:
25853334
32.

Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.

Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B.

Nat Commun. 2015 Mar 10;6:6496. doi: 10.1038/ncomms7496.

33.

Progenitor cell-derived extracellular vesicles: an emerging diagnostic and therapeutic tool for renal disease.

Braun GS, Moeller MJ.

Nephrol Dial Transplant. 2015 Mar;30(3):339-41. doi: 10.1093/ndt/gfv027. No abstract available.

PMID:
25712933
34.

Point: Proposing the electrokinetic model.

Moeller MJ, Kuppe C.

Perit Dial Int. 2015 Jan-Feb;35(1):5-8. doi: 10.3747/pdi.2014.00189. Review.

35.

From Patient to Dish and Back Again: Are We There Yet?

Kunter U, Moeller MJ.

J Am Soc Nephrol. 2015 Aug;26(8):1757-9. doi: 10.1681/ASN.2014111158. Epub 2015 Jan 7. No abstract available.

36.

Detection of activated parietal epithelial cells on the glomerular tuft distinguishes early focal segmental glomerulosclerosis from minimal change disease.

Smeets B, Stucker F, Wetzels J, Brocheriou I, Ronco P, Gröne HJ, D'Agati V, Fogo AB, van Kuppevelt TH, Fischer HP, Boor P, Floege J, Ostendorf T, Moeller MJ.

Am J Pathol. 2014 Dec;184(12):3239-48. doi: 10.1016/j.ajpath.2014.08.007. Epub 2014 Oct 7.

37.

Mechanisms of epithelial repair and regeneration after acute kidney injury.

Berger K, Moeller MJ.

Semin Nephrol. 2014 Jul;34(4):394-403. doi: 10.1016/j.semnephrol.2014.06.006. Epub 2014 Jun 13. Review.

38.

Glomerular disease: pre-eclampsia, podocyturia and the role of parietal epithelial cells.

Saritas T, Moeller MJ.

Nat Rev Nephrol. 2014 Nov;10(11):615-6. doi: 10.1038/nrneph.2014.163. Epub 2014 Sep 9. No abstract available.

PMID:
25201139
39.

The evolution of blood pressure and the rise of mankind.

Schulte K, Kunter U, Moeller MJ.

Nephrol Dial Transplant. 2015 May;30(5):713-23. doi: 10.1093/ndt/gfu275. Epub 2014 Aug 18. Review.

PMID:
25140012
40.

Role of parietal epithelial cells in kidney injury: the case of rapidly progressing glomerulonephritis and focal and segmental glomerulosclerosis.

Moeller MJ, Smeets B.

Nephron Exp Nephrol. 2014;126(2):97. doi: 10.1159/000360677. Epub 2014 May 19. Review.

41.

Renal lipidosis in patients enrolled in a methadone substitution program.

Porubsky S, Kuppe C, Maier T, Birk HW, Wörnle M, Moeller MJ, Floege J, Gröne HJ.

Arch Pathol Lab Med. 2014 May;138(5):689-93. doi: 10.5858/arpa.2013-0075-CR.

PMID:
24786128
42.

Origin of regenerating tubular cells after acute kidney injury.

Berger K, Bangen JM, Hammerich L, Liedtke C, Floege J, Smeets B, Moeller MJ.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1533-8. doi: 10.1073/pnas.1316177111. Epub 2014 Jan 13.

43.

Reply: podocytes are key-although albumin never reaches the slit diaphragm.

Moeller MJ, Tanner GA.

Nat Rev Nephrol. 2014 Mar;10(3):180. doi: 10.1038/nrneph.2013.58-c2. Epub 2014 Jan 28. No abstract available.

PMID:
24468773
44.

The emergence of the glomerular parietal epithelial cell.

Shankland SJ, Smeets B, Pippin JW, Moeller MJ.

Nat Rev Nephrol. 2014 Mar;10(3):158-73. doi: 10.1038/nrneph.2014.1. Epub 2014 Jan 28. Review.

PMID:
24468766
45.

Podocytopenia, parietal epithelial cells and glomerulosclerosis.

Berger K, Moeller MJ.

Nephrol Dial Transplant. 2014 May;29(5):948-50. doi: 10.1093/ndt/gft511. Epub 2014 Jan 20. No abstract available.

PMID:
24449103
46.

The regenerative potential of parietal epithelial cells in adult mice.

Berger K, Schulte K, Boor P, Kuppe C, van Kuppevelt TH, Floege J, Smeets B, Moeller MJ.

J Am Soc Nephrol. 2014 Apr;25(4):693-705. doi: 10.1681/ASN.2013050481. Epub 2014 Jan 9.

47.

Unraveling the role of podocyte turnover in glomerular aging and injury.

Wanner N, Hartleben B, Herbach N, Goedel M, Stickel N, Zeiser R, Walz G, Moeller MJ, Grahammer F, Huber TB.

J Am Soc Nephrol. 2014 Apr;25(4):707-16. doi: 10.1681/ASN.2013050452. Epub 2014 Jan 9.

48.

Two-photon microscopy reveals stationary podocytes in living zebrafish larvae.

Endlich N, Simon O, Göpferich A, Wegner H, Moeller MJ, Rumpel E, Kotb AM, Endlich K.

J Am Soc Nephrol. 2014 Apr;25(4):681-6. doi: 10.1681/ASN.2013020178. Epub 2013 Dec 5.

49.

Glomerular disease: the role of parietal epithelial cells in hyperplastic lesions.

Moeller MJ, Kuppe C.

Nat Rev Nephrol. 2014 Jan;10(1):5-6. doi: 10.1038/nrneph.2013.252. Epub 2013 Nov 26.

PMID:
24275836
50.

The terminator mouse: salvation for primary cell culture.

Kabgani N, Moeller MJ.

Kidney Int. 2013 Nov;84(5):866-8. doi: 10.1038/ki.2013.288.

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