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Items: 44

1.

Author Correction: Chimeric peptidomimetic antibiotics against Gram-negative bacteria.

Luther A, Urfer M, Zahn M, Müller M, Wang SY, Mondal M, Vitale A, Hartmann JB, Sharpe T, Monte FL, Kocherla H, Cline E, Pessi G, Rath P, Modaresi SM, Chiquet P, Stiegeler S, Verbree C, Remus T, Schmitt M, Kolopp C, Westwood MA, Desjonquères N, Brabet E, Hell S, LePoupon K, Vermeulen A, Jaisson R, Rithié V, Upert G, Lederer A, Zbinden P, Wach A, Moehle K, Zerbe K, Locher HH, Bernardini F, Dale GE, Eberl L, Wollscheid B, Hiller S, Robinson JA, Obrecht D.

Nature. 2019 Dec;576(7786):E5. doi: 10.1038/s41586-019-1810-2.

PMID:
31758154
2.

Chimeric peptidomimetic antibiotics against Gram-negative bacteria.

Luther A, Urfer M, Zahn M, Müller M, Wang SY, Mondal M, Vitale A, Hartmann JB, Sharpe T, Monte FL, Kocherla H, Cline E, Pessi G, Rath P, Modaresi SM, Chiquet P, Stiegeler S, Verbree C, Remus T, Schmitt M, Kolopp C, Westwood MA, Desjonquères N, Brabet E, Hell S, LePoupon K, Vermeulen A, Jaisson R, Rithié V, Upert G, Lederer A, Zbinden P, Wach A, Moehle K, Zerbe K, Locher HH, Bernardini F, Dale GE, Eberl L, Wollscheid B, Hiller S, Robinson JA, Obrecht D.

Nature. 2019 Oct 23. doi: 10.1038/s41586-019-1665-6. [Epub ahead of print] Erratum in: Nature. 2019 Nov 23;:.

PMID:
31645764
3.

Thanatin targets the intermembrane protein complex required for lipopolysaccharide transport in Escherichia coli.

Vetterli SU, Zerbe K, Müller M, Urfer M, Mondal M, Wang SY, Moehle K, Zerbe O, Vitale A, Pessi G, Eberl L, Wollscheid B, Robinson JA.

Sci Adv. 2018 Nov 14;4(11):eaau2634. doi: 10.1126/sciadv.aau2634. eCollection 2018 Nov.

4.

A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa.

Andolina G, Bencze LC, Zerbe K, Müller M, Steinmann J, Kocherla H, Mondal M, Sobek J, Moehle K, Malojčić G, Wollscheid B, Robinson JA.

ACS Chem Biol. 2018 Mar 16;13(3):666-675. doi: 10.1021/acschembio.7b00822. Epub 2018 Jan 23.

PMID:
29359918
5.

Protein Epitope Mimetics: From New Antibiotics to Supramolecular Synthetic Vaccines.

Zerbe K, Moehle K, Robinson JA.

Acc Chem Res. 2017 Jun 20;50(6):1323-1331. doi: 10.1021/acs.accounts.7b00129. Epub 2017 Jun 1. Review.

PMID:
28570824
6.

Protein epitope mimetic macrocycles as biopharmaceuticals.

Luther A, Moehle K, Chevalier E, Dale G, Obrecht D.

Curr Opin Chem Biol. 2017 Jun;38:45-51. doi: 10.1016/j.cbpa.2017.02.004. Epub 2017 Apr 20. Review.

PMID:
28319811
7.

Synthesis and antimicrobial activity against Pseudomonas aeruginosa of macrocyclic β-hairpin peptidomimetic antibiotics containing N-methylated amino acids.

Vetterli SU, Moehle K, Robinson JA.

Bioorg Med Chem. 2016 Dec 15;24(24):6332-6339. doi: 10.1016/j.bmc.2016.05.027. Epub 2016 May 18.

8.

Solution Structure and Dynamics of LptE from Pseudomonas aeruginosa.

Moehle K, Kocherla H, Bacsa B, Jurt S, Zerbe K, Robinson JA, Zerbe O.

Biochemistry. 2016 May 31;55(21):2936-43. doi: 10.1021/acs.biochem.6b00313. Epub 2016 May 19.

PMID:
27166502
9.

A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli.

Urfer M, Bogdanovic J, Lo Monte F, Moehle K, Zerbe K, Omasits U, Ahrens CH, Pessi G, Eberl L, Robinson JA.

J Biol Chem. 2016 Jan 22;291(4):1921-32. doi: 10.1074/jbc.M115.691725. Epub 2015 Dec 1.

10.

Structural studies of β-hairpin peptidomimetic antibiotics that target LptD in Pseudomonas sp.

Schmidt J, Patora-Komisarska K, Moehle K, Obrecht D, Robinson JA.

Bioorg Med Chem. 2013 Sep 15;21(18):5806-10. doi: 10.1016/j.bmc.2013.07.013. Epub 2013 Jul 17.

11.

Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors.

Mann A, Friedrich N, Krarup A, Weber J, Stiegeler E, Dreier B, Pugach P, Robbiani M, Riedel T, Moehle K, Robinson JA, Rusert P, Plückthun A, Trkola A.

J Virol. 2013 May;87(10):5868-81. doi: 10.1128/JVI.00152-13. Epub 2013 Mar 13.

12.

Synthesis of a 6,6-spiroketal amino acid and its incorporation into a peptide turn sequence using solid-phase peptide synthesis.

Kueh JT, Choi KW, Williams GM, Moehle K, Bacsa B, Robinson JA, Brimble MA.

Chemistry. 2013 Mar 18;19(12):3807-11. doi: 10.1002/chem.201204546. Epub 2013 Feb 19.

PMID:
23424080
13.

Synthetic virus-like particles and conformationally constrained peptidomimetics in vaccine design.

Riedel T, Ghasparian A, Moehle K, Rusert P, Trkola A, Robinson JA.

Chembiochem. 2011 Dec 16;12(18):2829-36. doi: 10.1002/cbic.201100586. Epub 2011 Nov 11.

14.

NMR studies of the solution conformation of the sex peptide from Drosophila melanogaster.

Moehle K, Freund A, Kubli E, Robinson JA.

FEBS Lett. 2011 Apr 20;585(8):1197-202. doi: 10.1016/j.febslet.2011.03.040. Epub 2011 Mar 23.

15.

Engineered synthetic virus-like particles and their use in vaccine delivery.

Ghasparian A, Riedel T, Koomullil J, Moehle K, Gorba C, Svergun DI, Perriman AW, Mann S, Tamborrini M, Pluschke G, Robinson JA.

Chembiochem. 2011 Jan 3;12(1):100-9. doi: 10.1002/cbic.201000536.

PMID:
21132689
16.

Peptidomimetic inhibitors targeting the CCR5-binding site on the human immunodeficiency virus type-1 gp120 glycoprotein complexed to CD4.

Seitz M, Rusert P, Moehle K, Trkola A, Robinson JA.

Chem Commun (Camb). 2010 Nov 7;46(41):7754-6. doi: 10.1039/c0cc02913k. Epub 2010 Sep 8.

17.

Recent progress in the discovery of macrocyclic compounds as potential anti-infective therapeutics.

Obrecht D, Robinson JA, Bernardini F, Bisang C, DeMarco SJ, Moehle K, Gombert FO.

Curr Med Chem. 2009;16(1):42-65. Review.

18.

The design, structures and therapeutic potential of protein epitope mimetics.

Robinson JA, Demarco S, Gombert F, Moehle K, Obrecht D.

Drug Discov Today. 2008 Nov;13(21-22):944-51. doi: 10.1016/j.drudis.2008.07.008. Epub 2008 Sep 11. Review.

PMID:
18725320
19.

Synthetic virus-like particles from self-assembling coiled-coil lipopeptides and their use in antigen display to the immune system.

Boato F, Thomas RM, Ghasparian A, Freund-Renard A, Moehle K, Robinson JA.

Angew Chem Int Ed Engl. 2007;46(47):9015-8. No abstract available.

PMID:
17935102
20.

Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA.

Moehle K, Athanassiou Z, Patora K, Davidson A, Varani G, Robinson JA.

Angew Chem Int Ed Engl. 2007;46(47):9101-4. No abstract available.

21.

Biaryl amino acid templates in place of D-Pro-L-Pro in cyclic beta-hairpin cationic antimicrobial peptidomimetics.

Srinivas N, Moehle K, Abou-Hadeed K, Obrecht D, Robinson JA.

Org Biomol Chem. 2007 Oct 7;5(19):3100-5. Epub 2007 Aug 17.

PMID:
17878968
22.

Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation.

Okitsu SL, Kienzl U, Moehle K, Silvie O, Peduzzi E, Mueller MS, Sauerwein RW, Matile H, Zurbriggen R, Mazier D, Robinson JA, Pluschke G.

Chem Biol. 2007 May;14(5):577-87.

23.

Structure-guided peptidomimetic design leads to nanomolar beta-hairpin inhibitors of the Tat-TAR interaction of bovine immunodeficiency virus.

Athanassiou Z, Patora K, Dias RL, Moehle K, Robinson JA, Varani G.

Biochemistry. 2007 Jan 23;46(3):741-51.

PMID:
17223695
24.

Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from Plasmodium falciparum merozoite surface protein-1.

James S, Moehle K, Renard A, Mueller MS, Vogel D, Zurbriggen R, Pluschke G, Robinson JA.

Chembiochem. 2006 Dec;7(12):1943-50.

PMID:
17068840
25.

Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles.

DeMarco SJ, Henze H, Lederer A, Moehle K, Mukherjee R, Romagnoli B, Robinson JA, Brianza F, Gombert FO, Lociuro S, Ludin C, Vrijbloed JW, Zumbrunn J, Obrecht JP, Obrecht D, Brondani V, Hamy F, Klimkait T.

Bioorg Med Chem. 2006 Dec 15;14(24):8396-404. Epub 2006 Sep 28.

PMID:
17010618
26.

Structure-activity studies in a family of beta-hairpin protein epitope mimetic inhibitors of the p53-HDM2 protein-protein interaction.

Fasan R, Dias RL, Moehle K, Zerbe O, Obrecht D, Mittl PR, Grütter MG, Robinson JA.

Chembiochem. 2006 Mar;7(3):515-26.

PMID:
16511824
27.

Protein ligand design: from phage display to synthetic protein epitope mimetics in human antibody Fc-binding peptidomimetics.

Dias RL, Fasan R, Moehle K, Renard A, Obrecht D, Robinson JA.

J Am Chem Soc. 2006 Mar 1;128(8):2726-32.

PMID:
16492060
28.

Crystal structure of an NPNA-repeat motif from the circumsporozoite protein of the malaria parasite Plasmodium falciparum.

Ghasparian A, Moehle K, Linden A, Robinson JA.

Chem Commun (Camb). 2006 Jan 14;(2):174-6. Epub 2005 Nov 21.

PMID:
16372096
29.
30.

Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction.

Fasan R, Dias RL, Moehle K, Zerbe O, Vrijbloed JW, Obrecht D, Robinson JA.

Angew Chem Int Ed Engl. 2004 Apr 13;43(16):2109-12. No abstract available.

PMID:
15083458
31.

A family of macrocyclic antibiotics with a mixed peptide-peptoid beta-hairpin backbone conformation.

Shankaramma SC, Moehle K, James S, Vrijbloed JW, Obrecht D, Robinson JA.

Chem Commun (Camb). 2003 Aug 7;(15):1842-3.

PMID:
12931994
32.

A virosome-mimotope approach to synthetic vaccine design and optimization: synthesis, conformation, and immune recognition of a potential malaria-vaccine candidate.

Pfeiffer B, Peduzzi E, Moehle K, Zurbriggen R, Glück R, Pluschke G, Robinson JA.

Angew Chem Int Ed Engl. 2003 May 30;42(21):2368-71. No abstract available.

PMID:
12783498
33.

Macrocyclic hairpin mimetics of the cationic antimicrobial peptide protegrin I: a new family of broad-spectrum antibiotics.

Shankaramma SC, Athanassiou Z, Zerbe O, Moehle K, Mouton C, Bernardini F, Vrijbloed JW, Obrecht D, Robinson JA.

Chembiochem. 2002 Nov 4;3(11):1126-33.

PMID:
12404639
34.

Exploiting conformationally constrained peptidomimetics and an efficient human-compatible delivery system in synthetic vaccine design.

Moreno R, Jiang L, Moehle K, Zurbriggen R, Glück R, Robinson JA, Pluschke G.

Chembiochem. 2001 Nov 5;2(11):838-43. Erratum in: Chembiochem 2002 Apr 2;3(4):270.

PMID:
11948870
35.

A new family of beta-hairpin mimetics based on a trypsin inhibitor from sunflower seeds.

Descours A, Moehle K, Renard A, Robinson JA.

Chembiochem. 2002 Apr 2;3(4):318-23.

PMID:
11933232
36.

Peptides and peptoids--a quantum chemical structure comparison.

Moehle K, Hofmann HJ.

Biopolymers. 1996 Jun;38(6):781-90.

PMID:
8652798
37.

Models of aging and neuropsychological test performance decline with aging.

Moehle KA, Long CJ.

J Gerontol. 1989 Nov;44(6):P176-7.

PMID:
2809110
38.

Statistical and diagnostic adequacy of a short form of the Halstead Category Test.

Moehle KA, Fitzhugh-Bell KB, Engleman E, Hennon D.

Int J Neurosci. 1988 Sep;42(1-2):107-12.

PMID:
3209366
39.

Laterality of brain damage and emotional disturbance in adults.

Moehle KA, Fitzhugh-Bell KB.

Arch Clin Neuropsychol. 1988;3(2):137-44.

PMID:
14591266
40.
41.
42.

Statistical test of a short form of the speech-sounds perception test in a child population.

Moehle KA, Berg RA, Lancaster W, Huch K.

J Clin Neuropsychol. 1984 Aug;6(3):337-40.

PMID:
6590574
43.
44.

Language-related skills in children with acute lymphocytic leukemia.

Moehle KA, Berg RA, Ch'ien LT, Lancaster W.

J Dev Behav Pediatr. 1983 Dec;4(4):257-61.

PMID:
6198335

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