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Items: 1 to 50 of 57


Development of a 2-dimensional atlas of the human kidney with imaging mass cytometry.

Singh N, Avigan ZM, Kliegel JA, Shuch BM, Montgomery RR, Moeckel GW, Cantley LG.

JCI Insight. 2019 Jun 20;4(12). pii: 129477. doi: 10.1172/jci.insight.129477. eCollection 2019 Jun 20.


Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern.

Roy SF, Ko CJ, Moeckel GW, Mcniff JM.

J Cutan Pathol. 2019 Oct;46(10):742-747. doi: 10.1111/cup.13522. Epub 2019 Jul 5.


Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis.

Moledina DG, Wilson FP, Pober JS, Perazella MA, Singh N, Luciano RL, Obeid W, Lin H, Kuperman M, Moeckel GW, Kashgarian M, Cantley LG, Parikh CR.

JCI Insight. 2019 May 16;4(10). pii: 127456. doi: 10.1172/jci.insight.127456. eCollection 2019 May 16.


Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease.

Landau SI, Guo X, Velazquez H, Torres R, Olson E, Garcia-Milian R, Moeckel GW, Desir GV, Safirstein R.

Kidney Int. 2019 Apr;95(4):797-814. doi: 10.1016/j.kint.2018.11.042.


Update on the Native Kidney Biopsy: Core Curriculum 2019.

Luciano RL, Moeckel GW.

Am J Kidney Dis. 2019 Mar;73(3):404-415. doi: 10.1053/j.ajkd.2018.10.011. Epub 2019 Jan 17. Review.


Telavancin-associated acute kidney injury

Cavanaugh C, Moeckel GW, Perazella MA.

Clin Nephrol. 2019 Mar;91(3):187-191. doi: 10.5414/CN109651.


TREX1 Mutation Causing Autosomal Dominant Thrombotic Microangiopathy and CKD-A Novel Presentation.

Gulati A, Bale AE, Dykas DJ, Bia MJ, Danovitch GM, Moeckel GW, Somlo S, Dahl NK.

Am J Kidney Dis. 2018 Dec;72(6):895-899. doi: 10.1053/j.ajkd.2018.05.006. Epub 2018 Jun 22. Review.


Pathologic Perspectives on Acute Tubular Injury Assessment in the Kidney Biopsy.

Moeckel GW.

Semin Nephrol. 2018 Jan;38(1):21-30. doi: 10.1016/j.semnephrol.2017.09.003. Review.


A case of severe nephrotoxicity associated with long-term dietary supplement use.

Koraishy FM, Moeckel GW, Geller DS.

Clin Nephrol. 2017 Aug 2. doi: 10.5414/CNCS109180. [Epub ahead of print]


Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI.

Nakazawa D, Kumar SV, Marschner J, Desai J, Holderied A, Rath L, Kraft F, Lei Y, Fukasawa Y, Moeckel GW, Angelotti ML, Liapis H, Anders HJ.

J Am Soc Nephrol. 2017 Jun;28(6):1753-1768. doi: 10.1681/ASN.2016080925. Epub 2017 Jan 10.


Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney.

Stankewich MC, Moeckel GW, Ji L, Ardito T, Morrow JS.

PLoS One. 2016 Jan 4;11(1):e0142687. doi: 10.1371/journal.pone.0142687. eCollection 2016.


Antiphospholipid Antibody Syndrome: Raised Intracranial Pressure Without Cerebral Venous Sinus Thrombosis.

Rudich DS, Yun SH, Liebling A, Silbert JE, Moeckel GW, Lesser RL.

J Neuroophthalmol. 2015 Dec;35(4):396-9. doi: 10.1097/WNO.0000000000000277.


Quantification and localization of M2 macrophages in human kidneys with acute tubular injury.

Palmer MB, Vichot AA, Cantley LG, Moeckel GW.

Int J Nephrol Renovasc Dis. 2014 Nov 7;7:415-9. doi: 10.2147/IJNRD.S66936. eCollection 2014.


GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury.

Huen SC, Huynh L, Marlier A, Lee Y, Moeckel GW, Cantley LG.

J Am Soc Nephrol. 2015 Jun;26(6):1334-45. doi: 10.1681/ASN.2014060612. Epub 2014 Nov 11.


Role of medullary progenitor cells in epithelial cell migration and proliferation.

Chen D, Chen Z, Zhang Y, Park C, Al-Omari A, Moeckel GW.

Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F64-74. doi: 10.1152/ajprenal.00547.2013. Epub 2014 May 7.


Cytomegalovirus glomerulopathy and cytomegalovirus interstitial nephritis on sequential transplant kidney biopsies.

Vichot AA, Formica RN Jr, Moeckel GW.

Am J Kidney Dis. 2014 Mar;63(3):536-9. doi: 10.1053/j.ajkd.2013.08.021. Epub 2013 Oct 25.


Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation.

Fretz JA, Nelson T, Velazquez H, Xi Y, Moeckel GW, Horowitz MC.

Kidney Int. 2014 May;85(5):1091-102. doi: 10.1038/ki.2013.433. Epub 2013 Oct 30.


Warfarin-related nephropathy in a patient with mild IgA nephropathy on dabigatran and aspirin.

Moeckel GW, Luciano RL, Brewster UC.

Clin Kidney J. 2013 Oct;6(5):507-9. doi: 10.1093/ckj/sft076. Epub 2013 Sep 10.


Hypertonic stress and cell death. Focus on "Multiple cell death pathways are independently activated by lethal hypertonicity in renal epithelial cells".

Moeckel GW.

Am J Physiol Cell Physiol. 2013 Nov 15;305(10):C1009-10. doi: 10.1152/ajpcell.00263.2013. Epub 2013 Sep 4. No abstract available.


Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms.

Chen D, Chen Z, Park C, Centrella M, McCarthy T, Chen L, Al-Omari A, Moeckel GW.

Gene. 2013 Nov 15;531(1):23-30. doi: 10.1016/j.gene.2013.08.047. Epub 2013 Aug 30.


Macrophage-specific deletion of transforming growth factor-β1 does not prevent renal fibrosis after severe ischemia-reperfusion or obstructive injury.

Huen SC, Moeckel GW, Cantley LG.

Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F477-84. doi: 10.1152/ajprenal.00624.2012. Epub 2013 Jun 12.


NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy.

Knauf F, Asplin JR, Granja I, Schmidt IM, Moeckel GW, David RJ, Flavell RA, Aronson PS.

Kidney Int. 2013 Nov;84(5):895-901. doi: 10.1038/ki.2013.207. Epub 2013 Jun 5.


Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome.

Lemaire M, Frémeaux-Bacchi V, Schaefer F, Choi M, Tang WH, Le Quintrec M, Fakhouri F, Taque S, Nobili F, Martinez F, Ji W, Overton JD, Mane SM, Nürnberg G, Altmüller J, Thiele H, Morin D, Deschenes G, Baudouin V, Llanas B, Collard L, Majid MA, Simkova E, Nürnberg P, Rioux-Leclerc N, Moeckel GW, Gubler MC, Hwa J, Loirat C, Lifton RP.

Nat Genet. 2013 May;45(5):531-6. doi: 10.1038/ng.2590. Epub 2013 Mar 31.


Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function.

Schmidt IM, Hall IE, Kale S, Lee S, He CH, Lee Y, Chupp GL, Moeckel GW, Lee CG, Elias JA, Parikh CR, Cantley LG.

J Am Soc Nephrol. 2013 Feb;24(2):309-19. doi: 10.1681/ASN.2012060579. Epub 2013 Jan 4.


Inorganic phosphate stimulates fibronectin expression in renal fibroblasts.

Chen Z, Chen D, McCarthy TL, Centrella M, Zhang Y, Moeckel GW.

Cell Physiol Biochem. 2012;30(1):151-9. doi: 10.1159/000339054. Epub 2012 Jun 18.


Intrarenal dopamine inhibits progression of diabetic nephropathy.

Zhang MZ, Yao B, Yang S, Yang H, Wang S, Fan X, Yin H, Fogo AB, Moeckel GW, Harris RC.

Diabetes. 2012 Oct;61(10):2575-84. Epub 2012 Jun 11.


Proteinuria and glomerular injury associated with the anti-angiogenesis drug Vargatef™.

Manjunath V, Moeckel GW, Mahnensmith R, Perazella MA.

NDT Plus. 2011 Dec;4(6):430-3. doi: 10.1093/ndtplus/sfr064. Epub 2011 Jun 1. No abstract available.


Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression.

Cheng H, Fan X, Moeckel GW, Harris RC.

J Am Soc Nephrol. 2011 Jul;22(7):1240-51. doi: 10.1681/ASN.2010111149.


SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function.

Jurczak MJ, Lee HY, Birkenfeld AL, Jornayvaz FR, Frederick DW, Pongratz RL, Zhao X, Moeckel GW, Samuel VT, Whaley JM, Shulman GI, Kibbey RG.

Diabetes. 2011 Mar;60(3):890-8. doi: 10.2337/db10-1328.


Podocyte vascular endothelial growth factor (Vegf₁₆₄) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes.

Veron D, Bertuccio CA, Marlier A, Reidy K, Garcia AM, Jimenez J, Velazquez H, Kashgarian M, Moeckel GW, Tufro A.

Diabetologia. 2011 May;54(5):1227-41. doi: 10.1007/s00125-010-2034-z. Epub 2011 Feb 12.


Nephrotoxicity from chemotherapeutic agents: clinical manifestations, pathobiology, and prevention/therapy.

Perazella MA, Moeckel GW.

Semin Nephrol. 2010 Nov;30(6):570-81. doi: 10.1016/j.semnephrol.2010.09.005. Review. Erratum in: Semin Nephrol. 2011 May;31(3):317.


Late-onset omeprazole-associated acute interstitial nephritis.

Ni N, Moeckel GW, Kumar C.

J Am Geriatr Soc. 2010 Dec;58(12):2443-4. doi: 10.1111/j.1532-5415.2010.03194.x. No abstract available.


Hematuria and decreased kidney function as initial signs of acute B-cell lymphoblastic leukemia.

Seo-Mayer P, Kenney B, McNamara J, Stein J, Moeckel GW.

Am J Kidney Dis. 2010 Nov;56(5):1001-5. doi: 10.1053/j.ajkd.2010.03.029.


Hypertonicity-induced mitochondrial membrane permeability in renal medullary interstitial cells: protective role of osmolytes.

Zhang L, Chen D, Chen Z, Moeckel GW.

Cell Physiol Biochem. 2010;25(6):753-60. doi: 10.1159/000315095. Epub 2010 May 18.


Deletion of the Met receptor in the collecting duct decreases renal repair following ureteral obstruction.

Ma H, Saenko M, Opuko A, Togawa A, Soda K, Marlier A, Moeckel GW, Cantley LG, Ishibe S.

Kidney Int. 2009 Oct;76(8):868-76. doi: 10.1038/ki.2009.304. Epub 2009 Aug 12.


Distinct roles for basal and induced COX-2 in podocyte injury.

Cheng H, Fan X, Guan Y, Moeckel GW, Zent R, Harris RC.

J Am Soc Nephrol. 2009 Sep;20(9):1953-62. doi: 10.1681/ASN.2009010039. Epub 2009 Jul 30.


Resolution of renal inflammation: a new role for NF-kappaB1 (p50) in inflammatory kidney diseases.

Panzer U, Steinmetz OM, Turner JE, Meyer-Schwesinger C, von Ruffer C, Meyer TN, Zahner G, Gómez-Guerrero C, Schmid RM, Helmchen U, Moeckel GW, Wolf G, Stahl RA, Thaiss F.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F429-39. doi: 10.1152/ajprenal.90435.2008. Epub 2009 May 20.


Placental insufficiency associated with loss of Cited1 causes renal medullary dysplasia.

Sparrow DB, Boyle SC, Sams RS, Mazuruk B, Zhang L, Moeckel GW, Dunwoodie SL, de Caestecker MP.

J Am Soc Nephrol. 2009 Apr;20(4):777-86. doi: 10.1681/ASN.2008050547. Epub 2009 Mar 18.


Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity.

Pozzi A, Jarad G, Moeckel GW, Coffa S, Zhang X, Gewin L, Eremina V, Hudson BG, Borza DB, Harris RC, Holzman LB, Phillips CL, Fassler R, Quaggin SE, Miner JH, Zent R.

Dev Biol. 2008 Apr 15;316(2):288-301. doi: 10.1016/j.ydbio.2008.01.022. Epub 2008 Jan 31.


Puromycin induces reversible proteinuric injury in transgenic mice expressing cyclooxygenase-2 in podocytes.

Jo YI, Cheng H, Wang S, Moeckel GW, Harris RC.

Nephron Exp Nephrol. 2007;107(3):e87-94. Epub 2007 Sep 21.


Overexpression of cyclooxygenase-2 predisposes to podocyte injury.

Cheng H, Wang S, Jo YI, Hao CM, Zhang M, Fan X, Kennedy C, Breyer MD, Moeckel GW, Harris RC.

J Am Soc Nephrol. 2007 Feb;18(2):551-9. Epub 2007 Jan 3.


Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.

Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, Pozzi A.

Kidney Int. 2006 Aug;70(3):460-70. Epub 2006 Jun 14.


Role of integrin alpha1beta1 in the regulation of renal medullary osmolyte concentration.

Moeckel GW, Zhang L, Chen X, Rossini M, Zent R, Pozzi A.

Am J Physiol Renal Physiol. 2006 Jan;290(1):F223-31. Epub 2005 Aug 16.


Expression of mediators of renal injury in the remnant kidney of ROP mice is attenuated by cyclooxygenase-2 inhibition.

Cheng H, Zhang M, Moeckel GW, Zhao Y, Wang S, Qi Z, Breyer MD, Harris RC.

Nephron Exp Nephrol. 2005;101(3):e75-85. Epub 2005 Jun 30.


Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry.

Lee W, Glaeser H, Smith LH, Roberts RL, Moeckel GW, Gervasini G, Leake BF, Kim RB.

J Biol Chem. 2005 Mar 11;280(10):9610-7. Epub 2005 Jan 4.


Adaptation of the nematode Caenorhabditis elegans to extreme osmotic stress.

Lamitina ST, Morrison R, Moeckel GW, Strange K.

Am J Physiol Cell Physiol. 2004 Apr;286(4):C785-91. Epub 2003 Nov 26.


COX2 activity promotes organic osmolyte accumulation and adaptation of renal medullary interstitial cells to hypertonic stress.

Moeckel GW, Zhang L, Fogo AB, Hao CM, Pozzi A, Breyer MD.

J Biol Chem. 2003 May 23;278(21):19352-7. Epub 2003 Mar 9.


Organic osmolytes betaine, sorbitol and inositol are potent inhibitors of erythrocyte membrane ATPases.

Moeckel GW, Shadman R, Fogel JM, Sadrzadeh SM.

Life Sci. 2002 Oct 4;71(20):2413-24.


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