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Items: 1 to 50 of 109


Development of a 2-dimensional atlas of the human kidney with imaging mass cytometry.

Singh N, Avigan ZM, Kliegel JA, Shuch BM, Montgomery RR, Moeckel GW, Cantley LG.

JCI Insight. 2019 Jun 20;4(12). pii: 129477. doi: 10.1172/jci.insight.129477. eCollection 2019 Jun 20.


Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern.

Roy SF, Ko CJ, Moeckel GW, Mcniff JM.

J Cutan Pathol. 2019 Oct;46(10):742-747. doi: 10.1111/cup.13522. Epub 2019 Jul 5.


Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis.

Moledina DG, Wilson FP, Pober JS, Perazella MA, Singh N, Luciano RL, Obeid W, Lin H, Kuperman M, Moeckel GW, Kashgarian M, Cantley LG, Parikh CR.

JCI Insight. 2019 May 16;4(10). pii: 127456. doi: 10.1172/jci.insight.127456. eCollection 2019 May 16.


Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease.

Landau SI, Guo X, Velazquez H, Torres R, Olson E, Garcia-Milian R, Moeckel GW, Desir GV, Safirstein R.

Kidney Int. 2019 Apr;95(4):797-814. doi: 10.1016/j.kint.2018.11.042.


Update on the Native Kidney Biopsy: Core Curriculum 2019.

Luciano RL, Moeckel GW.

Am J Kidney Dis. 2019 Mar;73(3):404-415. doi: 10.1053/j.ajkd.2018.10.011. Epub 2019 Jan 17. Review.


Telavancin-associated acute kidney injury

Cavanaugh C, Moeckel GW, Perazella MA.

Clin Nephrol. 2019 Mar;91(3):187-191. doi: 10.5414/CN109651.


Reliability of deceased-donor procurement kidney biopsy images uploaded in United Network for Organ Sharing.

Mansour SG, Hall IE, Reese PP, Jia Y, Thiessen-Philbrook H, Moeckel G, Weng FL, Revelo MP, Khalighi MA, Trivedi A, Doshi MD, Schröppel B, Parikh CR.

Clin Transplant. 2018 Dec;32(12):e13441. doi: 10.1111/ctr.13441. Epub 2018 Dec 6.


TREX1 Mutation Causing Autosomal Dominant Thrombotic Microangiopathy and CKD-A Novel Presentation.

Gulati A, Bale AE, Dykas DJ, Bia MJ, Danovitch GM, Moeckel GW, Somlo S, Dahl NK.

Am J Kidney Dis. 2018 Dec;72(6):895-899. doi: 10.1053/j.ajkd.2018.05.006. Epub 2018 Jun 22. Review.


The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery.

Stoppe C, Averdunk L, Goetzenich A, Soppert J, Marlier A, Kraemer S, Vieten J, Coburn M, Kowark A, Kim BS, Marx G, Rex S, Ochi A, Leng L, Moeckel G, Linkermann A, El Bounkari O, Zarbock A, Bernhagen J, Djudjaj S, Bucala R, Boor P.

Sci Transl Med. 2018 May 16;10(441). pii: eaan4886. doi: 10.1126/scitranslmed.aan4886.


Interstitial inflammation and interstitial fibrosis and tubular atrophy predict renal survival in lupus nephritis.

Wilson PC, Kashgarian M, Moeckel G.

Clin Kidney J. 2018 Apr;11(2):207-218. doi: 10.1093/ckj/sfx093. Epub 2017 Aug 31.


Semaphorin 7A in circulating regulatory T cells is increased in autosomal-dominant polycystic kidney disease and decreases with tolvaptan treatment.

Lee Y, Blount KL, Dai F, Thompson S, Scher JK, Bitterman S, Droher M, Herzog EL, Moeckel G, Karihaloo A, Dahl NK.

Clin Exp Nephrol. 2018 Aug;22(4):906-916. doi: 10.1007/s10157-018-1542-x. Epub 2018 Feb 16.


Pathologic Perspectives on Acute Tubular Injury Assessment in the Kidney Biopsy.

Moeckel GW.

Semin Nephrol. 2018 Jan;38(1):21-30. doi: 10.1016/j.semnephrol.2017.09.003. Review.


Granulomatosis With Polyangiitis in a Young Adult With Down Syndrome: Therapeutic Challenges and Clues to Immunopathogenesis.

Mensah KA, Malek Pascha V, Moeckel G, Danve A.

J Clin Rheumatol. 2018 Apr;24(3):153-156. doi: 10.1097/RHU.0000000000000633. No abstract available.


Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury.

Zhou H, Tian X, Tufro A, Moeckel G, Ishibe S, Goodwin J.

Sci Rep. 2017 Aug 29;7(1):9833. doi: 10.1038/s41598-017-10490-z.


A case of severe nephrotoxicity associated with long-term dietary supplement use.

Koraishy FM, Moeckel GW, Geller DS.

Clin Nephrol. 2017 Aug 2. doi: 10.5414/CNCS109180. [Epub ahead of print]


MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms.

Ochi A, Chen D, Schulte W, Leng L, Moeckel N, Piecychna M, Averdunk L, Stoppe C, Bucala R, Moeckel G.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F767-F780. doi: 10.1152/ajprenal.00683.2016. Epub 2017 May 24.


Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis.

Li A, Fan S, Xu Y, Meng J, Shen X, Mao J, Zhang L, Zhang X, Moeckel G, Wu D, Wu G, Liang C.

J Cell Mol Med. 2017 Aug;21(8):1619-1635. doi: 10.1111/jcmm.13091. Epub 2017 Feb 28.


Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI.

Nakazawa D, Kumar SV, Marschner J, Desai J, Holderied A, Rath L, Kraft F, Lei Y, Fukasawa Y, Moeckel GW, Angelotti ML, Liapis H, Anders HJ.

J Am Soc Nephrol. 2017 Jun;28(6):1753-1768. doi: 10.1681/ASN.2016080925. Epub 2017 Jan 10.


Eculizumab Therapy for Chronic Antibody-Mediated Injury in Kidney Transplant Recipients: A Pilot Randomized Controlled Trial.

Kulkarni S, Kirkiles-Smith NC, Deng YH, Formica RN, Moeckel G, Broecker V, Bow L, Tomlin R, Pober JS.

Am J Transplant. 2017 Mar;17(3):682-691. doi: 10.1111/ajt.14001. Epub 2016 Sep 16.


Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney.

Stankewich MC, Moeckel GW, Ji L, Ardito T, Morrow JS.

PLoS One. 2016 Jan 4;11(1):e0142687. doi: 10.1371/journal.pone.0142687. eCollection 2016.


Human polycystin-2 transgene dose-dependently rescues ADPKD phenotypes in Pkd2 mutant mice.

Li A, Tian X, Zhang X, Huang S, Ma Y, Wu D, Moeckel G, Somlo S, Wu G.

Am J Pathol. 2015 Oct;185(10):2843-60. doi: 10.1016/j.ajpath.2015.06.014.


A Nodular Foreign Body Reaction in a Dialysis Patient Receiving Long-term Treatment With Lanthanum Carbonate.

Valika AK, Jain D, Jaffe PE, Moeckel G, Brewster UC.

Am J Kidney Dis. 2016 Jan;67(1):128-32. doi: 10.1053/j.ajkd.2015.07.033. Epub 2015 Sep 16.


Three-Dimensional Morphology by Multiphoton Microscopy with Clearing in a Model of Cisplatin-Induced CKD.

Torres R, Velazquez H, Chang JJ, Levene MJ, Moeckel G, Desir GV, Safirstein R.

J Am Soc Nephrol. 2016 Apr;27(4):1102-12. doi: 10.1681/ASN.2015010079. Epub 2015 Aug 24.


Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes.

Hassan H, Tian X, Inoue K, Chai N, Liu C, Soda K, Moeckel G, Tufro A, Lee AH, Somlo S, Fedeles S, Ishibe S.

J Am Soc Nephrol. 2016 Apr;27(4):1055-65. doi: 10.1681/ASN.2015020191. Epub 2015 Aug 24.


Antiphospholipid Antibody Syndrome: Raised Intracranial Pressure Without Cerebral Venous Sinus Thrombosis.

Rudich DS, Yun SH, Liebling A, Silbert JE, Moeckel GW, Lesser RL.

J Neuroophthalmol. 2015 Dec;35(4):396-9. doi: 10.1097/WNO.0000000000000277.


Comparison of amyloid deposition in human kidney biopsies as predictor of poor patient outcome.

Castano E, Palmer MB, Vigneault C, Luciano R, Wong S, Moeckel G.

BMC Nephrol. 2015 Apr 29;16:64. doi: 10.1186/s12882-015-0046-0.


Chemokine receptor Cxcr4 contributes to kidney fibrosis via multiple effectors.

Yuan A, Lee Y, Choi U, Moeckel G, Karihaloo A.

Am J Physiol Renal Physiol. 2015 Mar 1;308(5):F459-72. doi: 10.1152/ajprenal.00146.2014. Epub 2014 Dec 23. Erratum in: Am J Physiol Renal Physiol. 2015 Jul 15;309(2):F183.


Semaphorin3a promotes advanced diabetic nephropathy.

Aggarwal PK, Veron D, Thomas DB, Siegel D, Moeckel G, Kashgarian M, Tufro A.

Diabetes. 2015 May;64(5):1743-59. doi: 10.2337/db14-0719. Epub 2014 Dec 4.


Quantification and localization of M2 macrophages in human kidneys with acute tubular injury.

Palmer MB, Vichot AA, Cantley LG, Moeckel GW.

Int J Nephrol Renovasc Dis. 2014 Nov 7;7:415-9. doi: 10.2147/IJNRD.S66936. eCollection 2014.


GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury.

Huen SC, Huynh L, Marlier A, Lee Y, Moeckel GW, Cantley LG.

J Am Soc Nephrol. 2015 Jun;26(6):1334-45. doi: 10.1681/ASN.2014060612. Epub 2014 Nov 11.


Bile acid nephropathy in a bodybuilder abusing an anabolic androgenic steroid.

Luciano RL, Castano E, Moeckel G, Perazella MA.

Am J Kidney Dis. 2014 Sep;64(3):473-6. doi: 10.1053/j.ajkd.2014.05.010. Epub 2014 Jun 18.


Role of medullary progenitor cells in epithelial cell migration and proliferation.

Chen D, Chen Z, Zhang Y, Park C, Al-Omari A, Moeckel GW.

Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F64-74. doi: 10.1152/ajprenal.00547.2013. Epub 2014 May 7.


Loss of polycystin-1 inhibits Bicc1 expression during mouse development.

Lian P, Li A, Li Y, Liu H, Liang D, Hu B, Lin D, Jiang T, Moeckel G, Qin D, Wu G.

PLoS One. 2014 Mar 3;9(3):e88816. doi: 10.1371/journal.pone.0088816. eCollection 2014.


Podocyte-specific VEGF-a gain of function induces nodular glomerulosclerosis in eNOS null mice.

Veron D, Aggarwal PK, Velazquez H, Kashgarian M, Moeckel G, Tufro A.

J Am Soc Nephrol. 2014 Aug;25(8):1814-24. doi: 10.1681/ASN.2013070752. Epub 2014 Feb 27.


Cytomegalovirus glomerulopathy and cytomegalovirus interstitial nephritis on sequential transplant kidney biopsies.

Vichot AA, Formica RN Jr, Moeckel GW.

Am J Kidney Dis. 2014 Mar;63(3):536-9. doi: 10.1053/j.ajkd.2013.08.021. Epub 2013 Oct 25.


Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.

Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S.

J Clin Invest. 2014 Mar;124(3):1098-113. doi: 10.1172/JCI69778. Epub 2014 Feb 17. Erratum in: J Clin Invest. 2015 Feb;125(2):882.


Renalase prevents AKI independent of amine oxidase activity.

Wang L, Velazquez H, Moeckel G, Chang J, Ham A, Lee HT, Safirstein R, Desir GV.

J Am Soc Nephrol. 2014 Jun;25(6):1226-35. doi: 10.1681/ASN.2013060665. Epub 2014 Feb 7.


Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia.

Shibata S, Rinehart J, Zhang J, Moeckel G, Castañeda-Bueno M, Stiegler AL, Boggon TJ, Gamba G, Lifton RP.

Cell Metab. 2013 Nov 5;18(5):660-71. doi: 10.1016/j.cmet.2013.10.005.


Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation.

Fretz JA, Nelson T, Velazquez H, Xi Y, Moeckel GW, Horowitz MC.

Kidney Int. 2014 May;85(5):1091-102. doi: 10.1038/ki.2013.433. Epub 2013 Oct 30.


Met activation is required for early cytoprotection after ischemic kidney injury.

Mason S, Hader C, Marlier A, Moeckel G, Cantley LG.

J Am Soc Nephrol. 2014 Feb;25(2):329-37. doi: 10.1681/ASN.2013050473. Epub 2013 Oct 17.


Warfarin-related nephropathy in a patient with mild IgA nephropathy on dabigatran and aspirin.

Moeckel GW, Luciano RL, Brewster UC.

Clin Kidney J. 2013 Oct;6(5):507-9. doi: 10.1093/ckj/sft076. Epub 2013 Sep 10.


Alloantibody and complement promote T cell-mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells.

Jane-Wit D, Manes TD, Yi T, Qin L, Clark P, Kirkiles-Smith NC, Abrahimi P, Devalliere J, Moeckel G, Kulkarni S, Tellides G, Pober JS.

Circulation. 2013 Dec 3;128(23):2504-16. doi: 10.1161/CIRCULATIONAHA.113.002972. Epub 2013 Sep 17.


Hypertonic stress and cell death. Focus on "Multiple cell death pathways are independently activated by lethal hypertonicity in renal epithelial cells".

Moeckel GW.

Am J Physiol Cell Physiol. 2013 Nov 15;305(10):C1009-10. doi: 10.1152/ajpcell.00263.2013. Epub 2013 Sep 4. No abstract available.


Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms.

Chen D, Chen Z, Park C, Centrella M, McCarthy T, Chen L, Al-Omari A, Moeckel GW.

Gene. 2013 Nov 15;531(1):23-30. doi: 10.1016/j.gene.2013.08.047. Epub 2013 Aug 30.


Macrophage-specific deletion of transforming growth factor-β1 does not prevent renal fibrosis after severe ischemia-reperfusion or obstructive injury.

Huen SC, Moeckel GW, Cantley LG.

Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F477-84. doi: 10.1152/ajprenal.00624.2012. Epub 2013 Jun 12.


NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy.

Knauf F, Asplin JR, Granja I, Schmidt IM, Moeckel GW, David RJ, Flavell RA, Aronson PS.

Kidney Int. 2013 Nov;84(5):895-901. doi: 10.1038/ki.2013.207. Epub 2013 Jun 5.


Babesiosis-induced acute kidney injury with prominent urinary macrophages.

Luciano RL, Moeckel G, Palmer M, Perazella MA.

Am J Kidney Dis. 2013 Oct;62(4):801-5. doi: 10.1053/j.ajkd.2013.02.376. Epub 2013 May 2.


Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome.

Lemaire M, Frémeaux-Bacchi V, Schaefer F, Choi M, Tang WH, Le Quintrec M, Fakhouri F, Taque S, Nobili F, Martinez F, Ji W, Overton JD, Mane SM, Nürnberg G, Altmüller J, Thiele H, Morin D, Deschenes G, Baudouin V, Llanas B, Collard L, Majid MA, Simkova E, Nürnberg P, Rioux-Leclerc N, Moeckel GW, Gubler MC, Hwa J, Loirat C, Lifton RP.

Nat Genet. 2013 May;45(5):531-6. doi: 10.1038/ng.2590. Epub 2013 Mar 31.


A 7-year-old boy with renal insufficiency and proteinuria after stem cell transplant for T-cell acute lymphoblastic leukemia.

Goodwin JE, Palmer M, Pashankar F, Tufro A, Moeckel G.

Clin Nephrol. 2014 Sep;82(3):205-10. doi: 10.5414/CN107767.


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