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Hypertrophy of human embryonic stem cell-derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals.

Deisl C, Fine M, Moe OW, Hilgemann DW.

Pflugers Arch. 2019 Aug;471(8):1143-1157. doi: 10.1007/s00424-019-02293-0. Epub 2019 Jun 28.


Treating Systemic Klotho Deficiency.

Pastor J, Moe OW.

Am J Nephrol. 2019;49(5):410-412. doi: 10.1159/000499864. Epub 2019 Apr 12. No abstract available.


Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience.

Ferrè S, Li X, Adams-Huet B, Maalouf NM, Sakhaee K, Toto RD, Moe OW, Neyra JA.

J Investig Med. 2019 Aug;67(6):987-994. doi: 10.1136/jim-2018-000966. Epub 2019 Mar 2.


Increased production and reduced urinary buffering of acid in uric acid stone formers is ameliorated by pioglitazone.

Maalouf NM, Poindexter JR, Adams-Huet B, Moe OW, Sakhaee K.

Kidney Int. 2019 May;95(5):1262-1268. doi: 10.1016/j.kint.2018.11.024. Epub 2019 Feb 19.


Net Acid Excretion and Urinary Organic Anions in Idiopathic Uric Acid Nephrolithiasis.

Bobulescu IA, Park SK, Xu LHR, Blanco F, Poindexter J, Adams-Huet B, Davidson TL, Sakhaee K, Maalouf NM, Moe OW.

Clin J Am Soc Nephrol. 2019 Mar 7;14(3):411-420. doi: 10.2215/CJN.10420818. Epub 2019 Feb 11.


Systemic Succinate Homeostasis and Local Succinate Signaling Affect Blood Pressure and Modify Risks for Calcium Oxalate Lithogenesis.

Khamaysi A, Anbtawee-Jomaa S, Fremder M, Eini-Rider H, Shimshilashvili L, Aharon S, Aizenshtein E, Shlomi T, Noguchi A, Springer D, Moe OW, Shcheynikov N, Muallem S, Ohana E.

J Am Soc Nephrol. 2019 Feb 6. pii: ASN.2018030277. doi: 10.1681/ASN.2018030277. [Epub ahead of print]


High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice.

Peri-Okonny P, Baskin KK, Iwamoto G, Mitchell JH, Smith SA, Kim HK, Szweda LI, Bassel-Duby R, Fujikawa T, Castorena CM, Richardson J, Shelton JM, Ayers C, Berry JD, Malladi VS, Hu MC, Moe OW, Scherer PE, Vongpatanasin W.

Circulation. 2019 Mar 12;139(11):1422-1434. doi: 10.1161/CIRCULATIONAHA.118.037550.


Role of αKlotho and FGF23 in regulation of type II Na-dependent phosphate co-transporters.

Hu MC, Shi M, Moe OW.

Pflugers Arch. 2019 Jan;471(1):99-108. doi: 10.1007/s00424-018-2238-5. Epub 2018 Dec 1. Review.


Control of metabolic predisposition to cardiovascular complications of chronic kidney disease by effervescent calcium magnesium citrate: a feasibility study.

Quiñones H, Hamdi T, Sakhaee K, Pasch A, Moe OW, Pak CYC.

J Nephrol. 2019 Feb;32(1):93-100. doi: 10.1007/s40620-018-0559-2. Epub 2018 Nov 21.


Impact of Acute Kidney Injury and CKD on Adverse Outcomes in Critically Ill Septic Patients.

Neyra JA, Mescia F, Li X, Adams-Huet B, Yessayan L, Yee J, Toto RD, Moe OW.

Kidney Int Rep. 2018 Jul 29;3(6):1344-1353. doi: 10.1016/j.ekir.2018.07.016. eCollection 2018 Nov.


Fibroblast growth factor 21 in chronic kidney disease.

Suassuna PGA, de Paula RB, Sanders-Pinheiro H, Moe OW, Hu MC.

J Nephrol. 2019 Jun;32(3):365-377. doi: 10.1007/s40620-018-0550-y. Epub 2018 Nov 14. Review.


Acute Kidney Injury After Burn: A Cohort Study From the Parkland Burn Intensive Care Unit.

Clark AT, Li X, Kulangara R, Adams-Huet B, Huen SC, Madni TD, Imran JB, Phelan HA, Arnoldo BD, Moe OW, Wolf SE, Neyra JA.

J Burn Care Res. 2019 Jan 1;40(1):72-78. doi: 10.1093/jbcr/iry046.


Incomplete Distal Renal Tubular Acidosis and Kidney Stones.

Fuster DG, Moe OW.

Adv Chronic Kidney Dis. 2018 Jul;25(4):366-374. doi: 10.1053/j.ackd.2018.05.007. Review.


Impact of Potassium Citrate vs Citric Acid on Urinary Stone Risk in Calcium Phosphate Stone Formers.

Doizi S, Poindexter JR, Pearle MS, Blanco F, Moe OW, Sakhaee K, Maalouf NM.

J Urol. 2018 Dec;200(6):1278-1284. doi: 10.1016/j.juro.2018.07.039. Epub 2018 Jul 20.


Author Correction: Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.

Fernández ÁF, Sebti S, Wei Y, Zou Z, Shi M, McMillan KL, He C, Ting T, Liu Y, Chiang WC, Marciano DK, Schiattarella GG, Bhagat G, Moe OW, Hu MC, Levine B.

Nature. 2018 Sep;561(7723):E30. doi: 10.1038/s41586-018-0270-4.


Cisplatin nephrotoxicity as a model of chronic kidney disease.

Shi M, McMillan KL, Wu J, Gillings N, Flores B, Moe OW, Hu MC.

Lab Invest. 2018 Aug;98(8):1105-1121. doi: 10.1038/s41374-018-0063-2. Epub 2018 Jun 1.


Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.

Fernández ÁF, Sebti S, Wei Y, Zou Z, Shi M, McMillan KL, He C, Ting T, Liu Y, Chiang WC, Marciano DK, Schiattarella GG, Bhagat G, Moe OW, Hu MC, Levine B.

Nature. 2018 Jun;558(7708):136-140. doi: 10.1038/s41586-018-0162-7. Epub 2018 May 30. Erratum in: Nature. 2018 Sep;561(7723):E30.


The Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol.

Song P, Zechner C, Hernandez G, Cánovas J, Xie Y, Sondhi V, Wagner M, Stadlbauer V, Horvath A, Leber B, Hu MC, Moe OW, Mangelsdorf DJ, Kliewer SA.

Cell Metab. 2018 Jun 5;27(6):1338-1347.e4. doi: 10.1016/j.cmet.2018.04.001. Epub 2018 Apr 12.


Effect of urine pH and magnesium on calcium oxalate saturation.

Ferrè S, Grange JS, Adams-Huet Ms B, Moe OW, Maalouf NM.

Magnes Res. 2017 Nov 1;30(4):107-119. doi: 10.1684/mrh.2018.0429.


Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation.

Johnson RJ, Bakris GL, Borghi C, Chonchol MB, Feldman D, Lanaspa MA, Merriman TR, Moe OW, Mount DB, Sanchez Lozada LG, Stahl E, Weiner DE, Chertow GM.

Am J Kidney Dis. 2018 Jun;71(6):851-865. doi: 10.1053/j.ajkd.2017.12.009. Epub 2018 Feb 27. Review.


Hyperuricosuric calcium urolithiasis.

Moe OW, Xu LHR.

J Nephrol. 2018 Apr;31(2):189-196. doi: 10.1007/s40620-018-0469-3. Epub 2018 Jan 24. Review.


α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.

Chen G, Liu Y, Goetz R, Fu L, Jayaraman S, Hu MC, Moe OW, Liang G, Li X, Mohammadi M.

Nature. 2018 Jan 25;553(7689):461-466. doi: 10.1038/nature25451. Epub 2018 Jan 17.


Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis.

Pathare G, Dhayat NA, Mohebbi N, Wagner CA, Bobulescu IA, Moe OW, Fuster DG.

Kidney Int. 2018 Apr;93(4):871-880. doi: 10.1016/j.kint.2017.10.018. Epub 2018 Jan 6.


Alpha-Klotho Enrichment in Induced Pluripotent Stem Cell Secretome Contributes to Antioxidative Protection in Acute Lung Injury.

Gazdhar A, Ravikumar P, Pastor J, Heller M, Ye J, Zhang J, Moe OW, Geiser T, Hsia CCW.

Stem Cells. 2018 Apr;36(4):616-625. doi: 10.1002/stem.2752. Epub 2017 Dec 25.


Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a "U-shaped" relationship.

Shi M, Flores B, Li P, Gillings N, McMillan KL, Ye J, Huang LJ, Sidhu SS, Zhong YP, Grompe MT, Streeter PR, Moe OW, Hu MC.

Am J Physiol Renal Physiol. 2018 Apr 1;314(4):F501-F516. doi: 10.1152/ajprenal.00306.2017. Epub 2017 Nov 29.


Association of serum magnesium with all-cause mortality in patients with and without chronic kidney disease in the Dallas Heart Study.

Ferrè S, Li X, Adams-Huet B, Maalouf NM, Sakhaee K, Toto RD, Moe OW, Neyra JA.

Nephrol Dial Transplant. 2018 Aug 1;33(8):1389-1396. doi: 10.1093/ndt/gfx275.


Furosemide/Fludrocortisone Test and Clinical Parameters to Diagnose Incomplete Distal Renal Tubular Acidosis in Kidney Stone Formers.

Dhayat NA, Gradwell MW, Pathare G, Anderegg M, Schneider L, Luethi D, Mattmann C, Moe OW, Vogt B, Fuster DG.

Clin J Am Soc Nephrol. 2017 Sep 7;12(9):1507-1517. doi: 10.2215/CJN.01320217. Epub 2017 Aug 3.


Dopamine reduces cell surface Na+/H+ exchanger-3 protein by decreasing NHE3 exocytosis and cell membrane recycling.

Hu MC, Bobulescu IA, Quiñones H, Gisler SM, Moe OW.

Am J Physiol Renal Physiol. 2017 Oct 1;313(4):F1018-F1025. doi: 10.1152/ajprenal.00251.2017. Epub 2017 Aug 2.


Crosstalk between kidney and bone - Bench to bedside.

Hruska KA, Lanske B, Moe OW.

Bone. 2017 Jul;100:1-3. doi: 10.1016/j.bone.2017.03.046. Epub 2017 Apr 11. No abstract available.


Recombinant α-Klotho may be prophylactic and therapeutic for acute to chronic kidney disease progression and uremic cardiomyopathy.

Hu MC, Shi M, Gillings N, Flores B, Takahashi M, Kuro-O M, Moe OW.

Kidney Int. 2017 May;91(5):1104-1114. doi: 10.1016/j.kint.2016.10.034. Epub 2017 Jan 25.


Temporal Changes in Kidney Stone Composition and in Risk Factors Predisposing to Stone Formation.

Xu LHR, Adams-Huet B, Poindexter JR, Maalouf NM, Moe OW, Sakhaee K.

J Urol. 2017 Jun;197(6):1465-1471. doi: 10.1016/j.juro.2017.01.057. Epub 2017 Jan 20.


Relationship between Urinary Calcium and Bone Mineral Density in Patients with Calcium Nephrolithiasis.

Sakhaee K, Maalouf NM, Poindexter J, Adams-Huet B, Moe OW.

J Urol. 2017 Jun;197(6):1472-1477. doi: 10.1016/j.juro.2017.01.002. Epub 2017 Jan 5.


Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression.

Rutkowski JM, Pastor J, Sun K, Park SK, Bobulescu IA, Chen CT, Moe OW, Scherer PE.

Kidney Int. 2017 Feb;91(2):324-337. doi: 10.1016/j.kint.2016.09.016. Epub 2016 Nov 30.


FGF23-αKlotho as a paradigm for a kidney-bone network.

Kuro-O M, Moe OW.

Bone. 2017 Jul;100:4-18. doi: 10.1016/j.bone.2016.11.013. Epub 2016 Nov 12. Review.


Renal phenotype in Bardet-Biedl syndrome: a combined defect of urinary concentration and dilution is associated with defective urinary AQP2 and UMOD excretion.

Zacchia M, Zacchia E, Zona E, Capolongo G, Raiola I, Rinaldi L, Trepiccione F, Ingrosso D, Perna A, Di Iorio V, Simonelli F, Moe OW, Capasso G.

Am J Physiol Renal Physiol. 2016 Oct 1;311(4):F686-F694. doi: 10.1152/ajprenal.00224.2016. Epub 2016 Aug 3.


Effects of Potassium Magnesium Citrate Supplementation on 24-Hour Ambulatory Blood Pressure and Oxidative Stress Marker in Prehypertensive and Hypertensive Subjects.

Vongpatanasin W, Peri-Okonny P, Velasco A, Arbique D, Wang Z, Ravikumar P, Adams-Huet B, Moe OW, Pak CYC.

Am J Cardiol. 2016 Sep 15;118(6):849-853. doi: 10.1016/j.amjcard.2016.06.041. Epub 2016 Jun 28.


The kidney stone and increased water intake trial in steel workers: results from a pilot study.

Lotan Y, Antonelli J, Jiménez IB, Gharbi H, Herring R, Beaver A, Dennis A, Von Merveldt D, Carter S, Cohen A, Poindexter J, Moe OW, Pearle MS.

Urolithiasis. 2017 Apr;45(2):177-183. doi: 10.1007/s00240-016-0892-7. Epub 2016 May 26.


High dietary phosphate intake induces hypertension and augments exercise pressor reflex function in rats.

Mizuno M, Mitchell JH, Crawford S, Huang CL, Maalouf N, Hu MC, Moe OW, Smith SA, Vongpatanasin W.

Am J Physiol Regul Integr Comp Physiol. 2016 Jul 1;311(1):R39-48. doi: 10.1152/ajpregu.00124.2016. Epub 2016 May 11.


Vitamin-D status and mineral metabolism in two ethnic populations with sarcoidosis.

Capolongo G, Xu LH, Accardo M, Sanduzzi A, Stanziola AA, Colao A, Agostini C, Zacchia M, Capasso G, Adams-Huet B, Moe OW, Maalouf NM, Sakhaee K, Hsia CC.

J Investig Med. 2016 Jun;64(5):1025-34. doi: 10.1136/jim-2016-000101. Epub 2016 Apr 6.


Drug-Induced Metabolic Acidosis.

Pham AQ, Xu LH, Moe OW.

F1000Res. 2015 Dec 16;4. pii: F1000 Faculty Rev-1460. doi: 10.12688/f1000research.7006.1. eCollection 2015. Review.


αKlotho deficiency in acute kidney injury contributes to lung damage.

Ravikumar P, Li L, Ye J, Shi M, Taniguchi M, Zhang J, Kuro-o M, Hu MC, Moe OW, Hsia CC.

J Appl Physiol (1985). 2016 Apr 1;120(7):723-32. doi: 10.1152/japplphysiol.00792.2015. Epub 2015 Dec 30.


αKlotho Mitigates Progression of AKI to CKD through Activation of Autophagy.

Shi M, Flores B, Gillings N, Bian A, Cho HJ, Yan S, Liu Y, Levine B, Moe OW, Hu MC.

J Am Soc Nephrol. 2016 Aug;27(8):2331-45. doi: 10.1681/ASN.2015060613. Epub 2015 Dec 23.


Nanoparticle facilitated inhalational delivery of erythropoietin receptor cDNA protects against hyperoxic lung injury.

Ravikumar P, Menon JU, Punnakitikashem P, Gyawali D, Togao O, Takahashi M, Zhang J, Ye J, Moe OW, Nguyen KT, Hsia CCW.

Nanomedicine. 2016 Apr;12(3):811-821. doi: 10.1016/j.nano.2015.10.004. Epub 2015 Oct 27.


The Vacuolar H+-ATPase B1 Subunit Polymorphism p.E161K Associates with Impaired Urinary Acidification in Recurrent Stone Formers.

Dhayat NA, Schaller A, Albano G, Poindexter J, Griffith C, Pasch A, Gallati S, Vogt B, Moe OW, Fuster DG.

J Am Soc Nephrol. 2016 May;27(5):1544-54. doi: 10.1681/ASN.2015040367. Epub 2015 Oct 9.


Renal Production, Uptake, and Handling of Circulating αKlotho.

Hu MC, Shi M, Zhang J, Addo T, Cho HJ, Barker SL, Ravikumar P, Gillings N, Bian A, Sidhu SS, Kuro-o M, Moe OW.

J Am Soc Nephrol. 2016 Jan;27(1):79-90. doi: 10.1681/ASN.2014101030. Epub 2015 May 14.


Relationship between serum uric Acid and bone mineral density in the general population and in rats with experimental hyperuricemia.

Zhang D, Bobulescu IA, Maalouf NM, Adams-Huet B, Poindexter J, Park S, Wei F, Chen C, Moe OW, Sakhaee K.

J Bone Miner Res. 2015 Jun;30(6):992-9. doi: 10.1002/jbmr.2430.


Fibroblast growth factor 23 and acute kidney injury.

Neyra JA, Moe OW, Hu MC.

Pediatr Nephrol. 2015 Nov;30(11):1909-18. doi: 10.1007/s00467-014-3006-1. Epub 2014 Dec 6. Review.


Klotho and phosphate are modulators of pathologic uremic cardiac remodeling.

Hu MC, Shi M, Cho HJ, Adams-Huet B, Paek J, Hill K, Shelton J, Amaral AP, Faul C, Taniguchi M, Wolf M, Brand M, Takahashi M, Kuro-O M, Hill JA, Moe OW.

J Am Soc Nephrol. 2015 Jun;26(6):1290-302. doi: 10.1681/ASN.2014050465. Epub 2014 Oct 17.


The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody.

Barker SL, Pastor J, Carranza D, Quiñones H, Griffith C, Goetz R, Mohammadi M, Ye J, Zhang J, Hu MC, Kuro-o M, Moe OW, Sidhu SS.

Nephrol Dial Transplant. 2015 Feb;30(2):223-33. doi: 10.1093/ndt/gfu291. Epub 2014 Oct 15.


Triglycerides in the human kidney cortex: relationship with body size.

Bobulescu IA, Lotan Y, Zhang J, Rosenthal TR, Rogers JT, Adams-Huet B, Sakhaee K, Moe OW.

PLoS One. 2014 Aug 29;9(8):e101285. doi: 10.1371/journal.pone.0101285. eCollection 2014.

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