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Items: 1 to 50 of 127

1.

An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors.

Wang T, Lu R, Kapur P, Jaiswal BS, Hannan R, Zhang Z, Pedrosa I, Luke JJ, Zhang H, Goldstein LD, Yousuf Q, Gu YF, McKenzie T, Joyce A, Kim MS, Wang X, Luo D, Onabolu O, Stevens C, Xie Z, Chen M, Filatenkov A, Torrealba J, Luo X, Guo W, He J, Stawiski E, Modrusan Z, Durinck S, Seshagiri S, Brugarolas J.

Cancer Discov. 2018 Jun 8. pii: CD-17-1246. doi: 10.1158/2159-8290.CD-17-1246. [Epub ahead of print]

PMID:
29884728
2.

Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis.

Denton CP, Ong VH, Xu S, Chen-Harris H, Modrusan Z, Lafyatis R, Khanna D, Jahreis A, Siegel J, Sornasse T.

Ann Rheum Dis. 2018 May 31. pii: annrheumdis-2018-213031. doi: 10.1136/annrheumdis-2018-213031. [Epub ahead of print]

3.

CRISPR off-target analysis in genetically engineered rats and mice.

Anderson KR, Haeussler M, Watanabe C, Janakiraman V, Lund J, Modrusan Z, Stinson J, Bei Q, Buechler A, Yu C, Thamminana SR, Tam L, Sowick MA, Alcantar T, O'Neil N, Li J, Ta L, Lima L, Roose-Girma M, Rairdan X, Durinck S, Warming S.

Nat Methods. 2018 Jul;15(7):512-514. doi: 10.1038/s41592-018-0011-5. Epub 2018 May 21.

PMID:
29786090
4.

ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy.

Jaiswal BS, Durinck S, Stawiski EW, Yin J, Wang W, Lin E, Moffat J, Martin SE, Modrusan Z, Seshagiri S.

Clin Cancer Res. 2018 May 14. doi: 10.1158/1078-0432.CCR-17-3674. [Epub ahead of print]

PMID:
29760222
5.

Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.

Nile AH, de Sousa E Melo F, Mukund S, Piskol R, Hansen S, Zhou L, Zhang Y, Fu Y, Gogol EB, Kömüves LG, Modrusan Z, Angers S, Franke Y, Koth C, Fairbrother WJ, Wang W, de Sauvage FJ, Hannoush RN.

Nat Chem Biol. 2018 May 4. doi: 10.1038/s41589-018-0069-5. [Epub ahead of print]

PMID:
29728602
6.

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes.

Arenzana TL, Lianoglou S, Seki A, Eidenschenk C, Cheung T, Seshasayee D, Hagenbeek T, Sambandam A, Noubade R, Peng I, Lesch J, DeVoss J, Wu X, Lee WP, Caplazi P, Webster J, Liu J, Pham VC, Arnott D, Lill JR, Modrusan Z, Dey A, Rutz S.

Sci Immunol. 2018 Apr 20;3(22). pii: eaal1953. doi: 10.1126/sciimmunol.aal1953.

PMID:
29678836
7.

A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.

Nile AH, de Sousa E Melo F, Mukund S, Piskol R, Hansen S, Zhou L, Zhang Y, Fu Y, Gogol EB, Kömüves LG, Modrusan Z, Angers S, Franke Y, Koth C, Fairbrother WJ, Wang W, de Sauvage FJ, Hannoush RN.

Nat Chem Biol. 2018 Jun;14(6):582-590. doi: 10.1038/s41589-018-0035-2. Epub 2018 Apr 9. Erratum in: Nat Chem Biol. 2018 May 4;:.

PMID:
29632413
8.

Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.

Germino EA, Miller JP, Diehl L, Swanson CJ, Durinck S, Modrusan Z, Miner JH, Shaw AS.

PLoS One. 2018 Mar 29;13(3):e0194998. doi: 10.1371/journal.pone.0194998. eCollection 2018.

9.

Comprehensive genomic analysis identifies pathogenic variants in maturity-onset diabetes of the young (MODY) patients in South India.

Mohan V, Radha V, Nguyen TT, Stawiski EW, Pahuja KB, Goldstein LD, Tom J, Anjana RM, Kong-Beltran M, Bhangale T, Jahnavi S, Chandni R, Gayathri V, George P, Zhang N, Murugan S, Phalke S, Chaudhuri S, Gupta R, Zhang J, Santhosh S, Stinson J, Modrusan Z, Ramprasad VL, Seshagiri S, Peterson AS.

BMC Med Genet. 2018 Feb 13;19(1):22. doi: 10.1186/s12881-018-0528-6.

10.

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.

Fazakerley DJ, Chaudhuri R, Yang P, Maghzal GJ, Thomas KC, Krycer JR, Humphrey SJ, Parker BL, Fisher-Wellman KH, Meoli CC, Hoffman NJ, Diskin C, Burchfield JG, Cowley MJ, Kaplan W, Modrusan Z, Kolumam G, Yang JY, Chen DL, Samocha-Bonet D, Greenfield JR, Hoehn KL, Stocker R, James DE.

Elife. 2018 Feb 6;7. pii: e32111. doi: 10.7554/eLife.32111.

11.

Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.

Friedman BA, Srinivasan K, Ayalon G, Meilandt WJ, Lin H, Huntley MA, Cao Y, Lee SH, Haddick PCG, Ngu H, Modrusan Z, Larson JL, Kaminker JS, van der Brug MP, Hansen DV.

Cell Rep. 2018 Jan 16;22(3):832-847. doi: 10.1016/j.celrep.2017.12.066.

12.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.

Brightbill HD, Suto E, Blaquiere N, Ramamoorthi N, Sujatha-Bhaskar S, Gogol EB, Castanedo GM, Jackson BT, Kwon YC, Haller S, Lesch J, Bents K, Everett C, Kohli PB, Linge S, Christian L, Barrett K, Jaochico A, Berezhkovskiy LM, Fan PW, Modrusan Z, Veliz K, Townsend MJ, DeVoss J, Johnson AR, Godemann R, Lee WP, Austin CD, McKenzie BS, Hackney JA, Crawford JJ, Staben ST, Alaoui Ismaili MH, Wu LC, Ghilardi N.

Nat Commun. 2018 Jan 12;9(1):179. doi: 10.1038/s41467-017-02672-0.

13.

SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer.

Viotti M, Wilson C, McCleland M, Koeppen H, Haley B, Jhunjhunwala S, Klijn C, Modrusan Z, Arnott D, Classon M, Stephan JP, Mellman I.

J Cell Biol. 2018 Feb 5;217(2):763-777. doi: 10.1083/jcb.201705031. Epub 2017 Dec 11.

PMID:
29229751
14.

Kras mutant genetically engineered mouse models of human cancers are genomically heterogeneous.

Chung WJ, Daemen A, Cheng JH, Long JE, Cooper JE, Wang BE, Tran C, Singh M, Gnad F, Modrusan Z, Foreman O, Junttila MR.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10947-E10955. doi: 10.1073/pnas.1708391114. Epub 2017 Dec 4.

15.

PRC2-mediated repression of SMARCA2 predicts EZH2 inhibitor activity in SWI/SNF mutant tumors.

Januario T, Ye X, Bainer R, Alicke B, Smith T, Haley B, Modrusan Z, Gould S, Yauch RL.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12249-12254. doi: 10.1073/pnas.1703966114. Epub 2017 Oct 30.

16.

Host-derived fatty acids activate type VII secretion in Staphylococcus aureus.

Lopez MS, Tan IS, Yan D, Kang J, McCreary M, Modrusan Z, Austin CD, Xu M, Brown EJ.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11223-11228. doi: 10.1073/pnas.1700627114. Epub 2017 Oct 2.

17.

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.

Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, Finley D, Brown EJ.

Elife. 2017 Sep 21;6. pii: e26435. doi: 10.7554/eLife.26435.

18.

Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia.

Cuellar TL, Herzner AM, Zhang X, Goyal Y, Watanabe C, Friedman BA, Janakiraman V, Durinck S, Stinson J, Arnott D, Cheung TK, Chaudhuri S, Modrusan Z, Doerr JM, Classon M, Haley B.

J Cell Biol. 2017 Nov 6;216(11):3535-3549. doi: 10.1083/jcb.201612160. Epub 2017 Sep 8.

19.

Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer.

Jin L, Garcia J, Chan E, de la Cruz C, Segal E, Merchant M, Kharbanda S, Raisner R, Haverty PM, Modrusan Z, Ly J, Choo E, Kaufman S, Beresini MH, Romero FA, Magnuson S, Gascoigne KE.

Cancer Res. 2017 Oct 15;77(20):5564-5575. doi: 10.1158/0008-5472.CAN-17-0314. Epub 2017 Aug 17.

PMID:
28819026
20.

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.

Le Pichon CE, Meilandt WJ, Dominguez S, Solanoy H, Lin H, Ngu H, Gogineni A, Sengupta Ghosh A, Jiang Z, Lee SH, Maloney J, Gandham VD, Pozniak CD, Wang B, Lee S, Siu M, Patel S, Modrusan Z, Liu X, Rudhard Y, Baca M, Gustafson A, Kaminker J, Carano RAD, Huang EJ, Foreman O, Weimer R, Scearce-Levie K, Lewcock JW.

Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394. doi: 10.1126/scitranslmed.aag0394.

21.

Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation.

Chang MC, Srinivasan K, Friedman BA, Suto E, Modrusan Z, Lee WP, Kaminker JS, Hansen DV, Sheng M.

J Exp Med. 2017 Sep 4;214(9):2611-2628. doi: 10.1084/jem.20160999. Epub 2017 Aug 4.

22.

Massively parallel nanowell-based single-cell gene expression profiling.

Goldstein LD, Chen YJ, Dunne J, Mir A, Hubschle H, Guillory J, Yuan W, Zhang J, Stinson J, Jaiswal B, Pahuja KB, Mann I, Schaal T, Chan L, Anandakrishnan S, Lin CW, Espinoza P, Husain S, Shapiro H, Swaminathan K, Wei S, Srinivasan M, Seshagiri S, Modrusan Z.

BMC Genomics. 2017 Jul 7;18(1):519. doi: 10.1186/s12864-017-3893-1.

23.

Stem cell plasticity enables hair regeneration following Lgr5+ cell loss.

Hoeck JD, Biehs B, Kurtova AV, Kljavin NM, de Sousa E Melo F, Alicke B, Koeppen H, Modrusan Z, Piskol R, de Sauvage FJ.

Nat Cell Biol. 2017 Jun;19(6):666-676. doi: 10.1038/ncb3535. Epub 2017 May 29.

PMID:
28553937
24.

Corrigendum: A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action.

Chai N, Swem LR, Park S, Nakamura G, Chiang N, Estevez A, Fong R, Kamen L, Kho E, Reichelt M, Lin Z, Chiu H, Skippington E, Modrusan Z, Stinson J, Xu M, Lupardus P, Ciferri C, Tan MW.

Nat Commun. 2017 May 25;8:15779. doi: 10.1038/ncomms15779.

25.

Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult.

Larhammar M, Huntwork-Rodriguez S, Jiang Z, Solanoy H, Sengupta Ghosh A, Wang B, Kaminker JS, Huang K, Eastham-Anderson J, Siu M, Modrusan Z, Farley MM, Tessier-Lavigne M, Lewcock JW, Watkins TA.

Elife. 2017 Apr 25;6. pii: e20725. doi: 10.7554/eLife.20725.

26.

The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation.

Senger K, Pham VC, Varfolomeev E, Hackney JA, Corzo CA, Collier J, Lau VWC, Huang Z, Hamidzhadeh K, Caplazi P, Peng I, Setiadi AF, Francis R, Paler-Martinez A, Kwon YC, Ramirez-Carrozzi V, Sun Y, Grigg PW, Roose-Girma M, Jeet S, Barck KH, Pham A, Ota N, Ha C, Stinson J, Guillory J, Tam L, Modrusan Z, Emson C, McKenzie BS, Townsend MJ, Carano RAD, Warming S, Vucic D, DeVoss J, Lee WP, Lill JR, Zarrin AA.

Sci Signal. 2017 Apr 18;10(475). pii: eaah4273. doi: 10.1126/scisignal.aah4273.

PMID:
28420753
27.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Katewa A, Wang Y, Hackney JA, Huang T, Suto E, Ramamoorthi N, Austin CD, Bremer M, Chen JZ, Crawford JJ, Currie KS, Blomgren P, DeVoss J, DiPaolo JA, Hau J, Johnson A, Lesch J, DeForge LE, Lin Z, Liimatta M, Lubach JW, McVay S, Modrusan Z, Nguyen A, Poon C, Wang J, Liu L, Lee WP, Wong H, Young WB, Townsend MJ, Reif K.

JCI Insight. 2017 Apr 6;2(7):e90111. doi: 10.1172/jci.insight.90111.

28.

Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types.

Chen YJ, Friedman BA, Ha C, Durinck S, Liu J, Rubenstein JL, Seshagiri S, Modrusan Z.

Sci Rep. 2017 Mar 31;7:45656. doi: 10.1038/srep45656.

29.

A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer.

de Sousa e Melo F, Kurtova AV, Harnoss JM, Kljavin N, Hoeck JD, Hung J, Anderson JE, Storm EE, Modrusan Z, Koeppen H, Dijkgraaf GJ, Piskol R, de Sauvage FJ.

Nature. 2017 Mar 29;543(7647):676-680. doi: 10.1038/nature21713.

PMID:
28358093
30.

A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action.

Chai N, Swem LR, Park S, Nakamura G, Chiang N, Estevez A, Fong R, Kamen L, Kho E, Reichelt M, Lin Z, Chiu H, Skippington E, Modrusan Z, Stinson J, Xu M, Lupardus P, Ciferri C, Tan MW.

Nat Commun. 2017 Jan 19;8:14234. doi: 10.1038/ncomms14234.

31.

Building proteomic tool boxes to monitor MHC class I and class II peptides.

Schumacher FR, Delamarre L, Jhunjhunwala S, Modrusan Z, Phung QT, Elias JE, Lill JR.

Proteomics. 2017 Jan;17(1-2). doi: 10.1002/pmic.201600061. Review.

PMID:
27928884
32.

A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase.

Morisaki JH, Smith PA, Date SV, Kajihara KK, Truong CL, Modrusan Z, Yan D, Kang J, Xu M, Shah IM, Mintzer R, Kofoed EM, Cheung TK, Arnott D, Koehler MF, Heise CE, Brown EJ, Tan MW, Hazenbos WL.

MBio. 2016 Sep 6;7(5). pii: e00412-16. doi: 10.1128/mBio.00412-16.

33.

Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.

Srinivasan K, Friedman BA, Larson JL, Lauffer BE, Goldstein LD, Appling LL, Borneo J, Poon C, Ho T, Cai F, Steiner P, van der Brug MP, Modrusan Z, Kaminker JS, Hansen DV.

Nat Commun. 2016 Apr 21;7:11295. doi: 10.1038/ncomms11295.

34.

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.

Bueno R, Stawiski EW, Goldstein LD, Durinck S, De Rienzo A, Modrusan Z, Gnad F, Nguyen TT, Jaiswal BS, Chirieac LR, Sciaranghella D, Dao N, Gustafson CE, Munir KJ, Hackney JA, Chaudhuri A, Gupta R, Guillory J, Toy K, Ha C, Chen YJ, Stinson J, Chaudhuri S, Zhang N, Wu TD, Sugarbaker DJ, de Sauvage FJ, Richards WG, Seshagiri S.

Nat Genet. 2016 Apr;48(4):407-16. doi: 10.1038/ng.3520. Epub 2016 Feb 29.

PMID:
26928227
35.

β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.

Suriben R, Kaihara KA, Paolino M, Reichelt M, Kummerfeld SK, Modrusan Z, Dugger DL, Newton K, Sagolla M, Webster JD, Liu J, Hebrok M, Dixit VM.

Cell. 2015 Dec 3;163(6):1457-67. doi: 10.1016/j.cell.2015.10.076. Epub 2015 Nov 25.

36.

Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity.

Chaudhuri R, Khoo PS, Tonks K, Junutula JR, Kolumam G, Modrusan Z, Samocha-Bonet D, Meoli CC, Hocking S, Fazakerley DJ, Stöckli J, Hoehn KL, Greenfield JR, Yang JYH, James DE.

NPJ Syst Biol Appl. 2015 Nov 12;1:15010. doi: 10.1038/npjsba.2015.10. eCollection 2015.

37.

Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice.

Hocking SL, Stewart RL, Brandon AE, Suryana E, Stuart E, Baldwin EM, Kolumam GA, Modrusan Z, Junutula JR, Gunton JE, Medynskyj M, Blaber SP, Karsten E, Herbert BR, James DE, Cooney GJ, Swarbrick MM.

Diabetologia. 2015 Jul;58(7):1587-600. doi: 10.1007/s00125-015-3583-y. Epub 2015 Apr 22.

PMID:
25899451
38.

IL-13 mediates IL-33-dependent mast cell and type 2 innate lymphoid cell effects on bronchial epithelial cells.

Nagarkar DR, Ramirez-Carrozzi V, Choy DF, Lee K, Soriano R, Jia G, Abbas AR, Modrusan Z, Pappu R, Arron JR.

J Allergy Clin Immunol. 2015 Jul;136(1):202-5. doi: 10.1016/j.jaci.2015.01.036. Epub 2015 Mar 14. No abstract available.

PMID:
25784274
39.

Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma.

Sharpe HJ, Pau G, Dijkgraaf GJ, Basset-Seguin N, Modrusan Z, Januario T, Tsui V, Durham AB, Dlugosz AA, Haverty PM, Bourgon R, Tang JY, Sarin KY, Dirix L, Fisher DC, Rudin CM, Sofen H, Migden MR, Yauch RL, de Sauvage FJ.

Cancer Cell. 2015 Mar 9;27(3):327-41. doi: 10.1016/j.ccell.2015.02.001.

40.

A comprehensive transcriptional portrait of human cancer cell lines.

Klijn C, Durinck S, Stawiski EW, Haverty PM, Jiang Z, Liu H, Degenhardt J, Mayba O, Gnad F, Liu J, Pau G, Reeder J, Cao Y, Mukhyala K, Selvaraj SK, Yu M, Zynda GJ, Brauer MJ, Wu TD, Gentleman RC, Manning G, Yauch RL, Bourgon R, Stokoe D, Modrusan Z, Neve RM, de Sauvage FJ, Settleman J, Seshagiri S, Zhang Z.

Nat Biotechnol. 2015 Mar;33(3):306-12. doi: 10.1038/nbt.3080. Epub 2014 Dec 8.

PMID:
25485619
41.

Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.

Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick DS, Lill JR, Ouyang W, Dixit VM.

Nature. 2015 Feb 19;518(7539):417-21. doi: 10.1038/nature13979. Epub 2014 Dec 3.

PMID:
25470037
42.

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing.

Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, Franci C, Cheung TK, Fritsche J, Weinschenk T, Modrusan Z, Mellman I, Lill JR, Delamarre L.

Nature. 2014 Nov 27;515(7528):572-6. doi: 10.1038/nature14001.

PMID:
25428506
43.

Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.

Durinck S, Stawiski EW, Pavía-Jiménez A, Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V, Nguyen TT, Pahuja KB, Chen YJ, Saleem S, Chaudhuri S, Heldens S, Jackson M, Peña-Llopis S, Guillory J, Toy K, Ha C, Harris CJ, Holloman E, Hill HM, Stinson J, Rivers CS, Janakiraman V, Wang W, Kinch LN, Grishin NV, Haverty PM, Chow B, Gehring JS, Reeder J, Pau G, Wu TD, Margulis V, Lotan Y, Sagalowsky A, Pedrosa I, de Sauvage FJ, Brugarolas J, Seshagiri S.

Nat Genet. 2015 Jan;47(1):13-21. doi: 10.1038/ng.3146. Epub 2014 Nov 17.

44.

Regulation of neuronal gene expression and survival by basal NMDA receptor activity: a role for histone deacetylase 4.

Chen Y, Wang Y, Modrusan Z, Sheng M, Kaminker JS.

J Neurosci. 2014 Nov 12;34(46):15327-39. doi: 10.1523/JNEUROSCI.0569-14.2014.

45.

Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis.

DePianto DJ, Chandriani S, Abbas AR, Jia G, N'Diaye EN, Caplazi P, Kauder SE, Biswas S, Karnik SK, Ha C, Modrusan Z, Matthay MA, Kukreja J, Collard HR, Egen JG, Wolters PJ, Arron JR.

Thorax. 2015 Jan;70(1):48-56. doi: 10.1136/thoraxjnl-2013-204596. Epub 2014 Sep 12.

46.

Diverse modes of genomic alteration in hepatocellular carcinoma.

Jhunjhunwala S, Jiang Z, Stawiski EW, Gnad F, Liu J, Mayba O, Du P, Diao J, Johnson S, Wong KF, Gao Z, Li Y, Wu TD, Kapadia SB, Modrusan Z, French DM, Luk JM, Seshagiri S, Zhang Z.

Genome Biol. 2014 Aug 26;15(8):436. doi: 10.1186/s13059-014-0436-9.

47.

Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts.

Chandriani S, DePianto DJ, N'Diaye EN, Abbas AR, Jackman J, Bevers J 3rd, Ramirez-Carrozzi V, Pappu R, Kauder SE, Toy K, Ha C, Modrusan Z, Wu LC, Collard HR, Wolters PJ, Egen JG, Arron JR.

J Immunol. 2014 Jul 1;193(1):111-9. doi: 10.4049/jimmunol.1301761. Epub 2014 May 30.

48.

Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.

Liu J, McCleland M, Stawiski EW, Gnad F, Mayba O, Haverty PM, Durinck S, Chen YJ, Klijn C, Jhunjhunwala S, Lawrence M, Liu H, Wan Y, Chopra V, Yaylaoglu MB, Yuan W, Ha C, Gilbert HN, Reeder J, Pau G, Stinson J, Stern HM, Manning G, Wu TD, Neve RM, de Sauvage FJ, Modrusan Z, Seshagiri S, Firestein R, Zhang Z.

Nat Commun. 2014 May 8;5:3830. doi: 10.1038/ncomms4830.

49.

An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth.

Adler AS, McCleland ML, Yee S, Yaylaoglu M, Hussain S, Cosino E, Quinones G, Modrusan Z, Seshagiri S, Torres E, Chopra VS, Haley B, Zhang Z, Blackwood EM, Singh M, Junttila M, Stephan JP, Liu J, Pau G, Fearon ER, Jiang Z, Firestein R.

Genes Dev. 2014 May 15;28(10):1068-84. doi: 10.1101/gad.237206.113. Epub 2014 May 1.

50.

Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.

Lee GY, Haverty PM, Li L, Kljavin NM, Bourgon R, Lee J, Stern H, Modrusan Z, Seshagiri S, Zhang Z, Davis D, Stokoe D, Settleman J, de Sauvage FJ, Neve RM.

Cancer Res. 2014 Jun 1;74(11):3114-26. doi: 10.1158/0008-5472.CAN-13-2683. Epub 2014 Apr 22.

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