Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 39

1.

Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.

Achour A, Broggini L, Han X, Sun R, Santambrogio C, Buratto J, Visentin C, Barbiroli A, De Luca CMG, Sormanni P, Moda F, De Simone A, Sandalova T, Grandori R, Camilloni C, Ricagno S.

FEBS J. 2019 Aug 17. doi: 10.1111/febs.15046. [Epub ahead of print]

PMID:
31420997
2.

Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy.

De Luca CMG, Elia AE, Portaleone SM, Cazzaniga FA, Rossi M, Bistaffa E, De Cecco E, Narkiewicz J, Salzano G, Carletta O, Romito L, Devigili G, Soliveri P, Tiraboschi P, Legname G, Tagliavini F, Eleopra R, Giaccone G, Moda F.

Transl Neurodegener. 2019 Aug 8;8:24. doi: 10.1186/s40035-019-0164-x. eCollection 2019.

3.

Novel screening approaches for human prion diseases drug discovery.

Moda F, Bolognesi ML, Legname G.

Expert Opin Drug Discov. 2019 Oct;14(10):983-993. doi: 10.1080/17460441.2019.1637851. Epub 2019 Jul 4.

PMID:
31271065
4.

Prion Efficiently Replicates in α-Synuclein Knockout Mice.

Bistaffa E, Rossi M, De Luca CMG, Cazzaniga F, Carletta O, Campagnani I, Tagliavini F, Legname G, Giaccone G, Moda F.

Mol Neurobiol. 2019 Apr 30. doi: 10.1007/s12035-019-1602-6. [Epub ahead of print]

PMID:
31041657
5.

PMCA-replicated PrPD in urine of vCJD patients maintains infectivity and strain characteristics of brain PrPD: Transmission study.

Cali I, Lavrich J, Moda F, Kofskey D, Nemani SK, Appleby B, Tagliavini F, Soto C, Gambetti P, Notari S.

Sci Rep. 2019 Mar 26;9(1):5191. doi: 10.1038/s41598-019-41694-0.

6.

Prions Strongly Reduce NMDA Receptor S-Nitrosylation Levels at Pre-symptomatic and Terminal Stages of Prion Diseases.

Meneghetti E, Gasperini L, Virgilio T, Moda F, Tagliavini F, Benetti F, Legname G.

Mol Neurobiol. 2019 Sep;56(9):6035-6045. doi: 10.1007/s12035-019-1505-6. Epub 2019 Feb 1.

PMID:
30710214
7.

Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State.

Visconti L, Malagrinò F, Broggini L, De Luca CMG, Moda F, Gianni S, Ricagno S, Toto A.

Int J Mol Sci. 2019 Jan 18;20(2). pii: E396. doi: 10.3390/ijms20020396.

8.

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene.

Di Fede G, Catania M, Atzori C, Moda F, Pasquali C, Indaco A, Grisoli M, Zuffi M, Guaita MC, Testi R, Taraglio S, Sessa M, Gusmaroli G, Spinelli M, Salzano G, Legname G, Tarletti R, Godi L, Pocchiari M, Tagliavini F, Imperiale D, Giaccone G.

Acta Neuropathol Commun. 2019 Jan 3;7(1):1. doi: 10.1186/s40478-018-0656-4.

9.

Sporadic MM-1 Type Creutzfeldt-Jakob Disease With Hemiballic Presentation and No Cognitive Impairment Until Death: How New NCJDRSU Diagnostic Criteria May Allow Early Diagnosis.

Saraceno L, Ricigliano VAG, Cavalli M, Cagol A, Bosco G, Moda F, Caroppo P, Meola G.

Front Neurol. 2018 Sep 5;9:739. doi: 10.3389/fneur.2018.00739. eCollection 2018.

10.

Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.

Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML.

J Med Chem. 2018 Sep 13;61(17):7640-7656. doi: 10.1021/acs.jmedchem.8b00610. Epub 2018 Aug 24.

PMID:
30078314
11.

Synthetic Prion Selection and Adaptation.

Bistaffa E, Moda F, Virgilio T, Campagnani I, De Luca CMG, Rossi M, Salzano G, Giaccone G, Tagliavini F, Legname G.

Mol Neurobiol. 2019 Apr;56(4):2978-2989. doi: 10.1007/s12035-018-1279-2. Epub 2018 Aug 3.

PMID:
30074230
12.

Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases.

Legname G, Virgilio T, Bistaffa E, De Luca CMG, Catania M, Zago P, Isopi E, Campagnani I, Tagliavini F, Giaccone G, Moda F.

Prion. 2018 Mar 4;12(2):127-137. doi: 10.1080/19336896.2018.1464367. Epub 2018 May 18.

13.

Molecular subtypes of Alzheimer's disease.

Di Fede G, Catania M, Maderna E, Ghidoni R, Benussi L, Tonoli E, Giaccone G, Moda F, Paterlini A, Campagnani I, Sorrentino S, Colombo L, Kubis A, Bistaffa E, Ghetti B, Tagliavini F.

Sci Rep. 2018 Feb 19;8(1):3269. doi: 10.1038/s41598-018-21641-1.

14.

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases.

Vanni S, Zattoni M, Moda F, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Carmona M, Ferrer I, Kovacs GG, Legname G.

Front Neurosci. 2018 Jan 22;12:8. doi: 10.3389/fnins.2018.00008. eCollection 2018.

15.

Differential overexpression of SERPINA3 in human prion diseases.

Vanni S, Moda F, Zattoni M, Bistaffa E, De Cecco E, Rossi M, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Ferrer I, Kovacs GG, Legname G.

Sci Rep. 2017 Nov 15;7(1):15637. doi: 10.1038/s41598-017-15778-8.

16.

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions.

Franceschini A, Baiardi S, Hughson AG, McKenzie N, Moda F, Rossi M, Capellari S, Green A, Giaccone G, Caughey B, Parchi P.

Sci Rep. 2017 Sep 6;7(1):10655. doi: 10.1038/s41598-017-10922-w.

17.

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.

Aulić S, Masperone L, Narkiewicz J, Isopi E, Bistaffa E, Ambrosetti E, Pastore B, De Cecco E, Scaini D, Zago P, Moda F, Tagliavini F, Legname G.

Sci Rep. 2017 Aug 30;7(1):10050. doi: 10.1038/s41598-017-10236-x.

18.

Biosafety of Prions.

Bistaffa E, Rossi M, De Luca CMG, Moda F.

Prog Mol Biol Transl Sci. 2017;150:455-485. doi: 10.1016/bs.pmbts.2017.06.017. Epub 2017 Aug 2. Review.

PMID:
28838674
19.

Protein Misfolding Cyclic Amplification of Infectious Prions.

Moda F.

Prog Mol Biol Transl Sci. 2017;150:361-374. doi: 10.1016/bs.pmbts.2017.06.016. Epub 2017 Jul 31. Review.

PMID:
28838669
20.

The Prion Concept and Synthetic Prions.

Legname G, Moda F.

Prog Mol Biol Transl Sci. 2017;150:147-156. doi: 10.1016/bs.pmbts.2017.06.002. Epub 2017 Jul 20. Review.

PMID:
28838659
21.

Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo.

Diaz-Espinoza R, Morales R, Concha-Marambio L, Moreno-Gonzalez I, Moda F, Soto C.

Mol Psychiatry. 2018 Mar;23(3):777-788. doi: 10.1038/mp.2017.84. Epub 2017 Jun 20.

22.

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia.

Redaelli V, Bistaffa E, Zanusso G, Salzano G, Sacchetto L, Rossi M, De Luca CM, Di Bari M, Portaleone SM, Agrimi U, Legname G, Roiter I, Forloni G, Tagliavini F, Moda F.

Sci Rep. 2017 Apr 7;7:46269. doi: 10.1038/srep46269.

23.

The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo.

Park KW, Eun Kim G, Morales R, Moda F, Moreno-Gonzalez I, Concha-Marambio L, Lee AS, Hetz C, Soto C.

Sci Rep. 2017 Mar 23;7:44723. doi: 10.1038/srep44723.

24.

Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease.

Concha-Marambio L, Pritzkow S, Moda F, Tagliavini F, Ironside JW, Schulz PE, Soto C.

Sci Transl Med. 2016 Dec 21;8(370):370ra183. doi: 10.1126/scitranslmed.aaf6188.

25.

Strain-dependent profile of misfolded prion protein aggregates.

Morales R, Hu PP, Duran-Aniotz C, Moda F, Diaz-Espinoza R, Chen B, Bravo-Alegria J, Makarava N, Baskakov IV, Soto C.

Sci Rep. 2016 Feb 15;6:20526. doi: 10.1038/srep20526.

26.

MRI abnormalities found 1 year prior to symptom onset in a case of Creutzfeldt-Jakob disease.

Verde F, Ticozzi N, Messina S, Calcagno N, Girotti F, Maderna L, Moda F, Scola E, Falini A, Tagliavini F, Silani V.

J Neurol. 2016 Mar;263(3):597-9. doi: 10.1007/s00415-016-8022-6. Epub 2016 Feb 12. No abstract available.

PMID:
26872662
27.

Tackling amyloidogenesis in Alzheimer's disease with A2V variants of Amyloid-β.

Di Fede G, Catania M, Maderna E, Morbin M, Moda F, Colombo L, Rossi A, Cagnotto A, Virgilio T, Palamara L, Ruggerone M, Giaccone G, Campagnani I, Costanza M, Pedotti R, Salvalaglio M, Salmona M, Tagliavini F.

Sci Rep. 2016 Feb 11;6:20949. doi: 10.1038/srep20949.

28.

Synthetic prions with novel strain-specified properties.

Moda F, Le TN, Aulić S, Bistaffa E, Campagnani I, Virgilio T, Indaco A, Palamara L, Andréoletti O, Tagliavini F, Legname G.

PLoS Pathog. 2015 Dec 31;11(12):e1005354. doi: 10.1371/journal.ppat.1005354. eCollection 2015 Dec.

29.

Grass plants bind, retain, uptake, and transport infectious prions.

Pritzkow S, Morales R, Moda F, Khan U, Telling GC, Hoover E, Soto C.

Cell Rep. 2015 May 26;11(8):1168-75. doi: 10.1016/j.celrep.2015.04.036. Epub 2015 May 14.

30.

Synthetic prions and other human neurodegenerative proteinopathies.

Le NT, Narkiewicz J, Aulić S, Salzano G, Tran HT, Scaini D, Moda F, Giachin G, Legname G.

Virus Res. 2015 Sep 2;207:25-37. doi: 10.1016/j.virusres.2014.10.020. Epub 2014 Oct 31. Review.

PMID:
25449570
31.

Prions in the urine of patients with variant Creutzfeldt-Jakob disease.

Moda F, Gambetti P, Notari S, Concha-Marambio L, Catania M, Park KW, Maderna E, Suardi S, Haïk S, Brandel JP, Ironside J, Knight R, Tagliavini F, Soto C.

N Engl J Med. 2014 Aug 7;371(6):530-9. doi: 10.1056/NEJMoa1404401.

32.

Defined α-synuclein prion-like molecular assemblies spreading in cell culture.

Aulić S, Le TT, Moda F, Abounit S, Corvaglia S, Casalis L, Gustincich S, Zurzolo C, Tagliavini F, Legname G.

BMC Neurosci. 2014 Jun 4;15:69. doi: 10.1186/1471-2202-15-69.

33.

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model.

Brunetti D, Dusi S, Morbin M, Uggetti A, Moda F, D'Amato I, Giordano C, d'Amati G, Cozzi A, Levi S, Hayflick S, Tiranti V.

Hum Mol Genet. 2012 Dec 15;21(24):5294-305. doi: 10.1093/hmg/dds380. Epub 2012 Sep 13.

34.

Brain delivery of AAV9 expressing an anti-PrP monovalent antibody delays prion disease in mice.

Moda F, Vimercati C, Campagnani I, Ruggerone M, Giaccone G, Morbin M, Zentilin L, Giacca M, Zucca I, Legname G, Tagliavini F.

Prion. 2012 Sep-Oct;6(4):383-90. doi: 10.4161/pri.20197. Epub 2012 Jul 30.

35.

Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein.

Wilson R, Plinston C, Hunter N, Casalone C, Corona C, Tagliavini F, Suardi S, Ruggerone M, Moda F, Graziano S, Sbriccoli M, Cardone F, Pocchiari M, Ingrosso L, Baron T, Richt J, Andreoletti O, Simmons M, Lockey R, Manson JC, Barron RM.

J Gen Virol. 2012 Jul;93(Pt 7):1624-9. doi: 10.1099/vir.0.042507-0. Epub 2012 Apr 11.

PMID:
22495232
36.

Infectivity in skeletal muscle of cattle with atypical bovine spongiform encephalopathy.

Suardi S, Vimercati C, Casalone C, Gelmetti D, Corona C, Iulini B, Mazza M, Lombardi G, Moda F, Ruggerone M, Campagnani I, Piccoli E, Catania M, Groschup MH, Balkema-Buschmann A, Caramelli M, Monaco S, Zanusso G, Tagliavini F.

PLoS One. 2012;7(2):e31449. doi: 10.1371/journal.pone.0031449. Epub 2012 Feb 21.

37.

MM2-thalamic Creutzfeldt-Jakob disease: neuropathological, biochemical and transmission studies identify a distinctive prion strain.

Moda F, Suardi S, Di Fede G, Indaco A, Limido L, Vimercati C, Ruggerone M, Campagnani I, Langeveld J, Terruzzi A, Brambilla A, Zerbi P, Fociani P, Bishop MT, Will RG, Manson JC, Giaccone G, Tagliavini F.

Brain Pathol. 2012 Sep;22(5):662-9. doi: 10.1111/j.1750-3639.2012.00572.x. Epub 2012 Feb 21.

PMID:
22288561
38.

A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles.

Ai Tran HN, Sousa F, Moda F, Mandal S, Chanana M, Vimercati C, Morbin M, Krol S, Tagliavini F, Legname G.

Nanoscale. 2010 Dec;2(12):2724-32. doi: 10.1039/c0nr00551g. Epub 2010 Oct 14.

PMID:
20944860
39.

Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features.

Giaccone G, Morbin M, Moda F, Botta M, Mazzoleni G, Uggetti A, Catania M, Moro ML, Redaelli V, Spagnoli A, Rossi RS, Salmona M, Di Fede G, Tagliavini F.

Acta Neuropathol. 2010 Dec;120(6):803-12. doi: 10.1007/s00401-010-0747-1. Epub 2010 Sep 15.

PMID:
20842367

Supplemental Content

Support Center