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Items: 28

1.

Correlating Gastrointestinal Histopathologic Changes to Clinical Disease Activity in Dogs With Idiopathic Inflammatory Bowel Disease.

Allenspach KA, Mochel JP, Du Y, Priestnall SL, Moore F, Slayter M, Rodrigues A, Ackermann M, Krockenberger M, Mansell J; WSAVA GI Standardization Working Group, Luckschander N, Wang C, Suchodolski J, Berghoff N, Jergens AE.

Vet Pathol. 2018 Dec 18:300985818813090. doi: 10.1177/0300985818813090. [Epub ahead of print]

PMID:
30563436
2.

Sacubitril/valsartan (LCZ696) significantly reduces aldosterone and increases cGMP circulating levels in a canine model of RAAS activation.

Mochel JP, Teng CH, Peyrou M, Giraudel J, Danhof M, Rigel DF.

Eur J Pharm Sci. 2019 Feb 1;128:103-111. doi: 10.1016/j.ejps.2018.11.037. Epub 2018 Nov 30.

PMID:
30508581
3.

Relative Oral Bioavailability of Two Amoxicillin-Clavulanic Acid Formulations in Healthy Dogs: A Pilot Study.

Moczarnik J, Berger DJ, Noxon JO, LeVine DN, Lin Z, Coetzee JF, Mochel JP.

J Am Anim Hosp Assoc. 2019 Jan/Feb;55(1):14-22. doi: 10.5326/JAAHA-MS-6872. Epub 2018 Nov 14.

PMID:
30427713
4.

Clinical features of cats with aqueous tear deficiency: a retrospective case series of 10 patients (17 eyes).

Uhl LK, Saito A, Iwashita H, Maggs DJ, Mochel JP, Sebbag L.

J Feline Med Surg. 2018 Nov 12:1098612X18810867. doi: 10.1177/1098612X18810867. [Epub ahead of print]

PMID:
30417738
5.

Retrospective evaluation of toceranib phosphate (Palladia®) use in the treatment of gastrointestinal stromal tumors of dogs.

Berger EP, Johannes CM, Jergens AE, Allenspach K, Powers BE, Du Y, Mochel JP, Fox LE, Musser ML.

J Vet Intern Med. 2018 Nov;32(6):2045-2053. doi: 10.1111/jvim.15335. Epub 2018 Oct 11.

6.

Comparative plasma and interstitial fluid pharmacokinetics and tissue residues of ceftiofur crystalline-free acid in cattle with induced coliform mastitis.

Gorden PJ, Ydstie JA, Kleinhenz MD, Brick TA, Smith JS, Griffith RW, Wulf LW, Rajewski SM, Zhang M, Sidhu PK, Mochel JP, Coetzee JF.

J Vet Pharmacol Ther. 2018 Dec;41(6):848-860. doi: 10.1111/jvp.12688. Epub 2018 Jul 4.

PMID:
29971798
7.

Adverse reactions to fentanyl transdermal patches in calves: a preliminary clinical and pharmacokinetic study.

Smith JS, Mochel JP, Borts DJ, Lewis KA, Coetzee JF.

Vet Anaesth Analg. 2018 Jul;45(4):575-580. doi: 10.1016/j.vaa.2018.02.009. Epub 2018 Apr 11.

PMID:
29880278
8.

Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation.

Martinez MN, Gehring R, Mochel JP, Pade D, Pelligand L.

J Vet Pharmacol Ther. 2018 Aug;41(4):E68-E76. doi: 10.1111/jvp.12666. Epub 2018 May 28. Review.

PMID:
29806231
9.

Impact of Flow Rate, Collection Devices, and Extraction Methods on Tear Concentrations Following Oral Administration of Doxycycline in Dogs and Cats.

Sebbag L, Showman L, McDowell EM, Perera A, Mochel JP.

J Ocul Pharmacol Ther. 2018 Jul/Aug;34(6):452-459. doi: 10.1089/jop.2018.0008. Epub 2018 Apr 30.

10.

Pharmacokinetics of fentanyl citrate and norfentanyl in Holstein calves and effect of analytical performances on fentanyl parameter estimation.

Smith JS, Coetzee JF, Fisher IWG, Borts DJ, Mochel JP.

J Vet Pharmacol Ther. 2018 Aug;41(4):555-561. doi: 10.1111/jvp.12501. Epub 2018 Mar 30.

PMID:
29603262
11.

Effects of short-term anti-inflammatory glucocorticoid treatment on clinicopathologic, echocardiographic, and hemodynamic variables in systemically healthy dogs.

Masters AK, Berger DJ, Ware WA, Langenfeld NR, Coetzee JF, Mochel JPM, Ward JL.

Am J Vet Res. 2018 Apr;79(4):411-423. doi: 10.2460/ajvr.79.4.411.

PMID:
29583045
12.

Effect of tear collection on lacrimal total protein content in dogs and cats: a comparison between Schirmer strips and ophthalmic sponges.

Sebbag L, McDowell EM, Hepner PM, Mochel JP.

BMC Vet Res. 2018 Mar 1;14(1):61. doi: 10.1186/s12917-018-1390-7.

13.

Comparison of milk and plasma pharmacokinetics of meloxicam in postpartum versus mid-lactation Holstein cows.

Gorden PJ, Burchard M, Ydstie JA, Kleinhenz MD, Wulf LW, Rajewski SJ, Wang C, Gehring R, Mochel JP, Coetzee JF.

J Vet Pharmacol Ther. 2018 Jun;41(3):463-468. doi: 10.1111/jvp.12488. Epub 2018 Feb 11.

PMID:
29430684
14.

Network on veterinary medicines initiated by the European Federation For Pharmaceutical Sciences.

Mochel JP, Tyden E, Hellmann K, Vendrig JC, Şenel S, Dencker L, Cristina RT, Linden H, Schmerold I.

J Vet Pharmacol Ther. 2018 Jun;41(3):378-383. doi: 10.1111/jvp.12472. Epub 2017 Dec 20.

PMID:
29266320
15.

Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research.

Mochel JP, Jergens AE, Kingsbury D, Kim HJ, Martín MG, Allenspach K.

AAPS J. 2017 Dec 12;20(1):17. doi: 10.1208/s12248-017-0178-1. Review.

16.

Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics.

Bon C, Toutain PL, Concordet D, Gehring R, Martin-Jimenez T, Smith J, Pelligand L, Martinez M, Whittem T, Riviere JE, Mochel JP.

J Vet Pharmacol Ther. 2018 Apr;41(2):171-183. doi: 10.1111/jvp.12473. Epub 2017 Dec 11. Review.

PMID:
29226975
17.

Model-Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative.

Schneider B, Balbas-Martinez V, Jergens AE, Troconiz IF, Allenspach K, Mochel JP.

CPT Pharmacometrics Syst Pharmacol. 2018 Feb;7(2):65-68. doi: 10.1002/psp4.12262. Epub 2017 Nov 27.

18.

Tear fluid collection in dogs and cats using ophthalmic sponges.

Sebbag L, Harrington DM, Mochel JP.

Vet Ophthalmol. 2018 May;21(3):249-254. doi: 10.1111/vop.12502. Epub 2017 Aug 27.

PMID:
28845579
19.

Multiple comparison procedure and modeling: a versatile tool for evaluating dose-response relationships in veterinary pharmacology - a case study with furosemide.

Bieth B, Bornkamp B, Toutain C, Garcia R, Mochel JP.

J Vet Pharmacol Ther. 2016 Dec;39(6):539-546. doi: 10.1111/jvp.12313. Epub 2016 May 11.

PMID:
27166146
20.

Modeling of Large Pharmacokinetic Data Using Nonlinear Mixed-Effects: A Paradigm Shift in Veterinary Pharmacology. A Case Study With Robenacoxib in Cats.

Pelligand L, Soubret A, King JN, Elliott J, Mochel JP.

CPT Pharmacometrics Syst Pharmacol. 2016 Nov;5(11):625-635. doi: 10.1002/psp4.12141. Epub 2016 Oct 22.

21.

Mathematical modeling and simulation in animal health - Part II: principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment.

Lin Z, Gehring R, Mochel JP, Lavé T, Riviere JE.

J Vet Pharmacol Ther. 2016 Oct;39(5):421-38. doi: 10.1111/jvp.12311. Epub 2016 Apr 17. Review.

PMID:
27086878
22.

Chronobiology and Pharmacologic Modulation of the Renin-Angiotensin-Aldosterone System in Dogs: What Have We Learned?

Mochel JP, Danhof M.

Rev Physiol Biochem Pharmacol. 2015;169:43-69. doi: 10.1007/112_2015_27. Review.

PMID:
26428686
23.

Pharmacokinetic/Pharmacodynamic Modeling of Renin-Angiotensin Aldosterone Biomarkers Following Angiotensin-Converting Enzyme (ACE) Inhibition Therapy with Benazepril in Dogs.

Mochel JP, Fink M, Peyrou M, Soubret A, Giraudel JM, Danhof M.

Pharm Res. 2015 Jun;32(6):1931-46. doi: 10.1007/s11095-014-1587-9. Epub 2014 Dec 2.

PMID:
25446774
24.

Influence of feeding schedules on the chronobiology of renin activity, urinary electrolytes and blood pressure in dogs.

Mochel JP, Fink M, Bon C, Peyrou M, Bieth B, Desevaux C, Deurinck M, Giraudel JM, Danhof M.

Chronobiol Int. 2014 Jun;31(5):715-30. doi: 10.3109/07420528.2014.897711. Epub 2014 Mar 21.

PMID:
24654920
25.

Chronobiology of the renin-angiotensin-aldosterone system in dogs: relation to blood pressure and renal physiology.

Mochel JP, Fink M, Peyrou M, Desevaux C, Deurinck M, Giraudel JM, Danhof M.

Chronobiol Int. 2013 Nov;30(9):1144-59. doi: 10.3109/07420528.2013.807275. Epub 2013 Aug 9.

PMID:
23931032
26.

Population pharmacokinetic analysis of blood concentrations of robenacoxib in dogs with osteoarthritis.

Fink M, Letellier I, Peyrou M, Mochel JP, Jung M, King JN, Gruet P, Giraudel JM.

Res Vet Sci. 2013 Oct;95(2):580-7. doi: 10.1016/j.rvsc.2013.04.021. Epub 2013 May 31.

PMID:
23726662
27.

Animal Health Modeling & Simulation Society: a new society promoting model-based approaches in veterinary pharmacology.

Mochel JP, Gabrielsson J, Collard W, Fink M, Gehring R, Laffont C, Liu Y, Martin-Jimenez T, Pelligand L, Steimer JL, Toutain PL, Whittem T, Riviere J.

J Vet Pharmacol Ther. 2013 May 29. doi: 10.1111/jvp.12060. [Epub ahead of print]

PMID:
23713757
28.

Capturing the dynamics of systemic Renin-Angiotensin-Aldosterone System (RAAS) peptides heightens the understanding of the effect of benazepril in dogs.

Mochel JP, Peyrou M, Fink M, Strehlau G, Mohamed R, Giraudel JM, Ploeger B, Danhof M.

J Vet Pharmacol Ther. 2013 Apr;36(2):174-80. doi: 10.1111/j.1365-2885.2012.01406.x. Epub 2012 May 8.

PMID:
22568394

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