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Items: 42


Rare variants in MYH15 modify amyotrophic lateral sclerosis risk.

Kim H, Lim J, Bao H, Jiao B, Canon SM, Epstein MP, Xu K, Jiang J, Parameswaran J, Li Y, Moberg KH, Landers JE, Fournier C, Allen EG, Glass JD, Wingo TS, Jin P.

Hum Mol Genet. 2019 Jul 15;28(14):2309-2318. doi: 10.1093/hmg/ddz063.


Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons.

Yao B, Li Y, Wang Z, Chen L, Poidevin M, Zhang C, Lin L, Wang F, Bao H, Jiao B, Lim J, Cheng Y, Huang L, Phillips BL, Xu T, Duan R, Moberg KH, Wu H, Jin P.

Mol Cell. 2018 Sep 6;71(5):848-857.e6. doi: 10.1016/j.molcel.2018.07.005. Epub 2018 Aug 2.


The domino SWI2/SNF2 Gene Product Represses Cell Death in Drosophila melanogaster.

Ellis K, Wardwell-Ozgo J, Moberg KH, Yedvobnick B.

G3 (Bethesda). 2018 Jul 2;8(7):2355-2360. doi: 10.1534/g3.118.200228.


The Conserved, Disease-Associated RNA Binding Protein dNab2 Interacts with the Fragile X Protein Ortholog in Drosophila Neurons.

Bienkowski RS, Banerjee A, Rounds JC, Rha J, Omotade OF, Gross C, Morris KJ, Leung SW, Pak C, Jones SK, Santoro MR, Warren ST, Zheng JQ, Bassell GJ, Corbett AH, Moberg KH.

Cell Rep. 2017 Aug 8;20(6):1372-1384. doi: 10.1016/j.celrep.2017.07.038.


The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice.

Rha J, Jones SK, Fidler J, Banerjee A, Leung SW, Morris KJ, Wong JC, Inglis GAS, Shapiro L, Deng Q, Cutler AA, Hanif AM, Pardue MT, Schaffer A, Seyfried NT, Moberg KH, Bassell GJ, Escayg A, García PS, Corbett AH.

Hum Mol Genet. 2017 Oct 1;26(19):3663-3681. doi: 10.1093/hmg/ddx248.


The ecdysone receptor coactivator Taiman links Yorkie to transcriptional control of germline stem cell factors in somatic tissue.

Zhang C, Robinson BS, Xu W, Yang L, Yao B, Zhao H, Byun PK, Jin P, Veraksa A, Moberg KH.

Dev Cell. 2015 Jul 27;34(2):168-80. doi: 10.1016/j.devcel.2015.05.010. Epub 2015 Jul 2.


The Drosophila ortholog of the Zc3h14 RNA binding protein acts within neurons to pattern axon projection in the developing brain.

Kelly SM, Bienkowski R, Banerjee A, Melicharek DJ, Brewer ZA, Marenda DR, Corbett AH, Moberg KH.

Dev Neurobiol. 2016 Jan;76(1):93-106. doi: 10.1002/dneu.22301. Epub 2015 Jun 1.


An intergenic regulatory region mediates Drosophila Myc-induced apoptosis and blocks tissue hyperplasia.

Zhang C, Casas-Tintó S, Li G, Lin N, Chung M, Moreno E, Moberg KH, Zhou L.

Oncogene. 2015 Apr 30;34(18):2412. doi: 10.1038/onc.2014.463. No abstract available.


Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.

Gross C, Chang CW, Kelly SM, Bhattacharya A, McBride SM, Danielson SW, Jiang MQ, Chan CB, Ye K, Gibson JR, Klann E, Jongens TA, Moberg KH, Huber KM, Bassell GJ.

Cell Rep. 2015 May 5;11(5):727-36. doi: 10.1016/j.celrep.2015.03.060. Epub 2015 Apr 23.


An intergenic regulatory region mediates Drosophila Myc-induced apoptosis and blocks tissue hyperplasia.

Zhang C, Casas-Tintó S, Li G, Lin N, Chung M, Moreno E, Moberg KH, Zhou L.

Oncogene. 2015 Apr 30;34(18):2385-97. doi: 10.1038/onc.2014.160. Epub 2014 Jun 16. Erratum in: Oncogene. 2015 Apr 30;34(18):2412.


A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length.

Kelly SM, Leung SW, Pak C, Banerjee A, Moberg KH, Corbett AH.

RNA. 2014 May;20(5):681-8. doi: 10.1261/rna.043984.113. Epub 2014 Mar 26.


The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression.

Mortimer NT, Moberg KH.

PLoS Genet. 2013;9(2):e1003314. doi: 10.1371/journal.pgen.1003314. Epub 2013 Feb 14.


Stable isotope labeling with amino acids in Drosophila for quantifying proteins and modifications.

Xu P, Tan H, Duong DM, Yang Y, Kupsco J, Moberg KH, Li H, Jin P, Peng J.

J Proteome Res. 2012 Sep 7;11(9):4403-12. doi: 10.1021/pr300613c. Epub 2012 Aug 10.


Regulation of Yorkie activity in Drosophila imaginal discs by the Hedgehog receptor gene patched.

Kagey JD, Brown JA, Moberg KH.

Mech Dev. 2012 Sep-Dec;129(9-12):339-49. doi: 10.1016/j.mod.2012.05.007. Epub 2012 Jun 15.


Drosophila endocytic neoplastic tumor suppressor genes regulate Sav/Wts/Hpo signaling and the c-Jun N-terminal kinase pathway.

Robinson BS, Moberg KH.

Cell Cycle. 2011 Dec 1;10(23):4110-8. doi: 10.4161/cc.10.23.18243. Epub 2011 Dec 1.


Cell-cell junctions: α-catenin and E-cadherin help fence in Yap1.

Robinson BS, Moberg KH.

Curr Biol. 2011 Nov 8;21(21):R890-2. doi: 10.1016/j.cub.2011.09.019.


Aeromonas salmonicida-secreted protein AopP is a potent inducer of apoptosis in a mammalian and a Drosophila model.

Jones RM, Luo L, Moberg KH.

Cell Microbiol. 2012 Feb;14(2):274-85. doi: 10.1111/j.1462-5822.2011.01717.x. Epub 2011 Nov 21.


Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans.

Pak C, Garshasbi M, Kahrizi K, Gross C, Apponi LH, Noto JJ, Kelly SM, Leung SW, Tzschach A, Behjati F, Abedini SS, Mohseni M, Jensen LR, Hu H, Huang B, Stahley SN, Liu G, Williams KR, Burdick S, Feng Y, Sanyal S, Bassell GJ, Ropers HH, Najmabadi H, Corbett AH, Moberg KH, Kuss AW.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12390-5. doi: 10.1073/pnas.1107103108. Epub 2011 Jul 6.


A screen for conditional growth suppressor genes identifies the Drosophila homolog of HD-PTP as a regulator of the oncoprotein Yorkie.

Gilbert MM, Tipping M, Veraksa A, Moberg KH.

Dev Cell. 2011 May 17;20(5):700-12. doi: 10.1016/j.devcel.2011.04.012.


Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye.

Nicholson SC, Nicolay BN, Frolov MV, Moberg KH.

Development. 2011 Jan;138(2):251-60. doi: 10.1242/dev.054429. Epub 2010 Dec 9.


A Drosophila melanogaster model of classic galactosemia.

Kushner RF, Ryan EL, Sefton JM, Sanders RD, Lucioni PJ, Moberg KH, Fridovich-Keil JL.

Dis Model Mech. 2010 Sep-Oct;3(9-10):618-27. doi: 10.1242/dmm.005041. Epub 2010 Jun 2.


UDP-galactose 4' epimerase (GALE) is essential for development of Drosophila melanogaster.

Sanders RD, Sefton JM, Moberg KH, Fridovich-Keil JL.

Dis Model Mech. 2010 Sep-Oct;3(9-10):628-38. doi: 10.1242/dmm.005058. Epub 2010 Jun 2.


Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded.

Robinson BS, Huang J, Hong Y, Moberg KH.

Curr Biol. 2010 Apr 13;20(7):582-90. doi: 10.1016/j.cub.2010.03.019. Epub 2010 Apr 1.


Functional interactions between the erupted/tsg101 growth suppressor gene and the DaPKC and rbf1 genes in Drosophila imaginal disc tumors.

Gilbert MM, Robinson BS, Moberg KH.

PLoS One. 2009 Sep 29;4(9):e7039. doi: 10.1371/journal.pone.0007039.


Genetic interactions between the Drosophila tumor suppressor gene ept and the stat92E transcription factor.

Gilbert MM, Beam CK, Robinson BS, Moberg KH.

PLoS One. 2009 Sep 29;4(9):e7083. doi: 10.1371/journal.pone.0007083.


The archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues.

Nicholson SC, Gilbert MM, Nicolay BN, Frolov MV, Moberg KH.

Curr Biol. 2009 Sep 29;19(18):1503-10. doi: 10.1016/j.cub.2009.07.068. Epub 2009 Sep 3.


Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia.

Mortimer NT, Moberg KH.

Dev Biol. 2009 May 15;329(2):294-305. doi: 10.1016/j.ydbio.2009.03.001. Epub 2009 Mar 11.


ESCRTing cell proliferation off the beaten path: lessons from the drosophila eye.

Gilbert MM, Moberg KH.

Cell Cycle. 2006 Feb;5(3):283-7. Epub 2006 Feb 1.


Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer.

Kwak EL, Moberg KH, Wahrer DC, Quinn JE, Gilmore PM, Graham CA, Hariharan IK, Harkin DP, Haber DA, Bell DW.

Gynecol Oncol. 2005 Jul;98(1):124-8.


The Drosophila F box protein archipelago regulates dMyc protein levels in vivo.

Moberg KH, Mukherjee A, Veraksa A, Artavanis-Tsakonas S, Hariharan IK.

Curr Biol. 2004 Jun 8;14(11):965-74.


Big things from a little RNA.

Moberg KH, Hariharan IK.

Trends Cell Biol. 2003 Sep;13(9):455-7. Review.


The coupling of cell growth to the cell cycle.

Tapon N, Moberg KH, Hariharan IK.

Curr Opin Cell Biol. 2001 Dec;13(6):731-7. Review.


Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines.

Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK.

Nature. 2001 Sep 20;413(6853):311-6.


Multiprotein complex formation on the c-myc promoter.

Logan TJ, Moberg KH, Hall DJ.

Biochem Mol Biol Int. 1997 Dec;43(5):945-53.


Growth suppression by members of the retinoblastoma protein family.

Zhu L, Enders GH, Wu CL, Starz MA, Moberg KH, Lees JA, Dyson N, Harlow E.

Cold Spring Harb Symp Quant Biol. 1994;59:75-84. Review. No abstract available.


Wild-type murine p53 represses transcription from the murine c-myc promoter in a human glial cell line.

Moberg KH, Tyndall WA, Hall DJ.

J Cell Biochem. 1992 Jun;49(2):208-15.


Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter.

Pyrc JJ, Moberg KH, Hall DJ.

Biochemistry. 1992 Apr 28;31(16):4102-10.


Three distinct elements within the murine c-myc promoter are required for transcription.

Moberg KH, Logan TJ, Tyndall WA, Hall DJ.

Oncogene. 1992 Mar;7(3):411-21.


Analysis of the c-myc P2 promoter.

Moberg KH, Tyndall WA, Pyrc J, Hall DJ.

J Cell Physiol. 1991 Jul;148(1):75-84.


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