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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 3
1987 4
1989 7
1990 4
1991 10
1992 26
1993 37
1994 67
1995 75
1996 129
1997 187
1998 252
1999 314
2000 422
2001 505
2002 566
2003 644
2004 754
2005 811
2006 909
2007 951
2008 1009
2009 1146
2010 1271
2011 1331
2012 1445
2013 1520
2014 1562
2015 1572
2016 1554
2017 1660
2018 1647
2019 1671
2020 1639
2021 1589
2022 1353
2023 1151
2024 380

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26,633 results

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OONO-/MMP2/MMP9 pathway-mediated apoptosis of porcine granulosa cells is associated with DNA damage.
Lei K, Wei Q, Cheng Y, Wang Z, Wu H, Zhao F, Ding W, Shi F. Lei K, et al. Reproduction. 2023 Mar 15;165(4):431-443. doi: 10.1530/REP-22-0295. Print 2023 Apr 1. Reproduction. 2023. PMID: 36745011
Furthermore, by inhibiting the activities of MMP2 and MMP9, we found that SB-3CT (a specific inhibitor for MMP2 and MMP9) alleviated the decrease in cell survival rates and DNA damage caused by OONO-, which may have been impacted by reducing the cleavage of PARP1 by …
Furthermore, by inhibiting the activities of MMP2 and MMP9, we found that SB-3CT (a specific inhibitor for MMP2 and MMP9) alle …
MMP2 and TLRs modulate immune responses in the tumor microenvironment.
Muniz-Bongers LR, McClain CB, Saxena M, Bongers G, Merad M, Bhardwaj N. Muniz-Bongers LR, et al. JCI Insight. 2021 Jun 22;6(12):e144913. doi: 10.1172/jci.insight.144913. JCI Insight. 2021. PMID: 34032639 Free PMC article.
B16 melanoma cells that express MMP2 at baseline have slower kinetics in Tlr2-/- Tlr4-/- mice, implicating MMP2 in promoting tumor growth. ...In contrast, knockdown of Mmp2 slowed tumor growth and enhanced T cell proliferation and NK cell recruitment. ...
B16 melanoma cells that express MMP2 at baseline have slower kinetics in Tlr2-/- Tlr4-/- mice, implicating MMP2 in promoting t …
Mmp2 Deficiency Leads to Defective Parturition and High Dystocia Rates in Mice.
Kalev-Altman R, Becker G, Levy T, Penn S, Shpigel NY, Monsonego-Ornan E, Sela-Donenfeld D. Kalev-Altman R, et al. Int J Mol Sci. 2023 Nov 27;24(23):16822. doi: 10.3390/ijms242316822. Int J Mol Sci. 2023. PMID: 38069145 Free PMC article.
Very high percentages of dystocia (40-55%) were found in the Mmp2(-/-) and dKO females, contrary to the Mmp9(-/-) and wild-type females. ...Increased collagen deposition was also demonstrated, suggesting a mechanism of extensive fibrosis in the Mmp2(-/-) myometrium, …
Very high percentages of dystocia (40-55%) were found in the Mmp2(-/-) and dKO females, contrary to the Mmp9(-/-) and wild-type femal …
MMP2 is a immunotherapy related biomarker and correlated with cancer-associated fibroblasts infiltrate in melanoma.
Peng K, Zhang Y, Liu D, Chen J. Peng K, et al. Cancer Cell Int. 2023 Feb 14;23(1):26. doi: 10.1186/s12935-023-02862-5. Cancer Cell Int. 2023. PMID: 36788565 Free PMC article.
RESULTS: In general, the expression of MMP2, MMP13, MMP16, MMP17 and MMP25 were significantly associated with skin cutaneous melanoma (SKCM) patients prognosis, among which MMP2 low expression benefited patients the most. Especially, the overall survival (OS) of BRA …
RESULTS: In general, the expression of MMP2, MMP13, MMP16, MMP17 and MMP25 were significantly associated with skin cutaneous melanoma …
MMP2 rs243866 and rs2285053 Polymorphisms and Alzheimer's Disease Risk in Slovak Caucasian Population.
Ocenasova A, Shawkatova I, Javor J, Parnicka Z, Minarik G, Kralova M, Kiralyova I, Mikolaskova I, Durmanova V. Ocenasova A, et al. Life (Basel). 2023 Mar 26;13(4):882. doi: 10.3390/life13040882. Life (Basel). 2023. PMID: 37109410 Free PMC article.
A total of 215 late-onset AD patients and 373 control subjects from Slovakia were genotyped for MMP2 rs243866 and rs2285053 polymorphisms. The MMP2 association with AD risk and clinical parameters was evaluated by logistic and linear regression analyses. ...However, …
A total of 215 late-onset AD patients and 373 control subjects from Slovakia were genotyped for MMP2 rs243866 and rs2285053 polymorph …
Relationships between abnormal MMP2 expression and prognosis in gastric cancer: a meta-analysis of cohort studies.
Wang HL, Zhou PY, Zhang Y, Liu P. Wang HL, et al. Cancer Biother Radiopharm. 2014 May;29(4):166-72. doi: 10.1089/cbr.2014.1608. Epub 2014 Apr 30. Cancer Biother Radiopharm. 2014. PMID: 24784911 Review.
Ten clinical cohort studies with a total of 1669 GC patients were included in this meta-analysis. The results of our meta-analysis suggested that MMP2-positive patients display a shorter overall survival (OS) than MMP2-negative patients (HR=1.31, 95% CI=0.98-1.63, p …
Ten clinical cohort studies with a total of 1669 GC patients were included in this meta-analysis. The results of our meta-analysis suggested …
Imaging application of an MMP2-sensitive tumor-targeted prussian blue fluorescent nanoprobe.
Zhou X, Zhang C, Zhou Q, Liang J, Zhang X, Shi Y, Zhu J, Zhong L. Zhou X, et al. J Biomater Appl. 2023 Sep;38(3):372-380. doi: 10.1177/08853282231194147. Epub 2023 Aug 2. J Biomater Appl. 2023. PMID: 37531192
Our research group has synthesized a kind of nanocarrier, mPEG2000-GPLGIAGQ-DSPE, which has the characteristic of matrix metalloproteinase-2 (MMP2) sensitive ability in tumor microenvironment. Meanwhile, the encapsulation method is adopted to prepare MMP2-sensitive …
Our research group has synthesized a kind of nanocarrier, mPEG2000-GPLGIAGQ-DSPE, which has the characteristic of matrix metalloproteinase-2 …
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression.
Chen J, Song T, Yang S, Meng Q, Han X, Wu Z, Cheng JC, Fang L. Chen J, et al. Cell Commun Signal. 2023 May 4;21(1):93. doi: 10.1186/s12964-023-01107-2. Cell Commun Signal. 2023. PMID: 37143106 Free PMC article.
The cell invasiveness was measured by Matrigel-coated transwell invasion assay. RESULTS: GDF-8 stimulated MMP2 expression in both HTR-8/SVneo and primary EVT cells. The stimulatory effect of GDF-8 on MMP2 expression was blocked by the inhibitor of TGF-beta type-I re …
The cell invasiveness was measured by Matrigel-coated transwell invasion assay. RESULTS: GDF-8 stimulated MMP2 expression in both HTR …
Association of MMP2-1306C/T Polymorphism with Ischemic Retinal Vein Occlusion.
Christodoulou A, Bagli E, Gazouli M, Moschos MM, Kitsos G. Christodoulou A, et al. Arch Med Res. 2020 Oct;51(7):710-713. doi: 10.1016/j.arcmed.2020.06.015. Epub 2020 Jul 6. Arch Med Res. 2020. PMID: 32646603
PURPOSE: To investigate the possible association of the matrix metalloproteinase 2 (MMP2)-1306C/T polymorphism with the risk of ischemic retinal vein occlusion (iRVO). ...RESULTS: MMP2-1306C/T T allele carriers (CT+TT) were statistically significant associated with …
PURPOSE: To investigate the possible association of the matrix metalloproteinase 2 (MMP2)-1306C/T polymorphism with the risk of ische …
MMP2 and MMP9 associate with crescentic glomerulonephritis.
Phillips TM, Fadia M, Lea-Henry TN, Smiles J, Walters GD, Jiang SH. Phillips TM, et al. Clin Kidney J. 2017 Apr;10(2):215-220. doi: 10.1093/ckj/sfw111. Epub 2016 Dec 26. Clin Kidney J. 2017. PMID: 28584626 Free PMC article.
This suggests that MMP2 and MMP9 are involved in the development of extracapillary proliferative lesions. Conclusions: MMP2/MMP9 is expressed with active extracapillary proliferation. ...
This suggests that MMP2 and MMP9 are involved in the development of extracapillary proliferative lesions. Conclusions: MMP2/MM …
26,633 results
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