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Items: 1 to 50 of 116

1.

Extensively drug-resistant tuberculosis 'hotspots' and sociodemographic associations in Durban, South Africa.

Peterson ML, Gandhi NR, Clennon J, Nelson KN, Morris N, Ismail N, Allana S, Campbell A, Brust JCM, Auld SC, Mathema B, Mlisana K, Moodley P, Shah NS.

Int J Tuberc Lung Dis. 2019 Jun 1;23(6):720-727. doi: 10.5588/ijtld.18.0575.

PMID:
31315705
2.

High rate of occult hepatitis B virus infection in hemodialysis units of KwaZulu-Natal, South Africa.

Msomi N, Ndlovu K, Giandhari J, Wilkinson E, Parboosing R, Zungu S, Mlisana K.

J Med Virol. 2019 Jun 10. doi: 10.1002/jmv.25510. [Epub ahead of print]

PMID:
31180137
3.

Computational, crystallographic studies, cytotoxicity and anti-tubercular activity of substituted 7-methoxy-indolizine analogues.

Venugopala KN, Chandrashekharappa S, Pillay M, Abdallah HH, Mahomoodally FM, Bhandary S, Chopra D, Attimarad M, Aldhubiab BE, Nair AB, Sreeharsha N, Morsy MA, Pottathil S, Venugopala R, Odhav B, Mlisana K.

PLoS One. 2019 Jun 4;14(6):e0217270. doi: 10.1371/journal.pone.0217270. eCollection 2019.

4.

rpoB Mutations Causing Discordant Rifampicin Susceptibility in Mycobacterium tuberculosis: Retrospective Analysis of Prevalence, Phenotypic, Genotypic, and Treatment Outcomes.

Mvelase NR, Pillay M, Sibanda W, Ngozo JN, Brust JCM, Mlisana KP.

Open Forum Infect Dis. 2019 Feb 12;6(4):ofz065. doi: 10.1093/ofid/ofz065. eCollection 2019 Apr.

5.

Diagnostic accuracy of the Xpert CT/NG and OSOM Trichomonas Rapid assays for point-of-care STI testing among young women in South Africa: a cross-sectional study.

Garrett N, Mitchev N, Osman F, Naidoo J, Dorward J, Singh R, Ngobese H, Rompalo A, Mlisana K, Mindel A.

BMJ Open. 2019 Feb 19;9(2):e026888. doi: 10.1136/bmjopen-2018-026888.

6.

Whole-Genome Sequence of a Novel Sequence Type 3136 Carbapenem-Resistant Klebsiella pneumoniae Strain Isolated from a Hospitalized Patient in Durban, South Africa.

Ramsamy Y, Mlisana KP, Allam M, Ismail A, Singh R, Amoako DG, Essack SY.

Microbiol Resour Announc. 2018 Dec 13;7(23). pii: e01300-18. doi: 10.1128/MRA.01300-18. eCollection 2018 Dec.

7.

Antibiotic resistance trends of ESKAPE pathogens in Kwazulu-Natal, South Africa: A five-year retrospective analysis.

Ramsamy Y, Essack SY, Sartorius B, Patel M, Mlisana KP.

Afr J Lab Med. 2018 Dec 6;7(2):887. doi: 10.4102/ajlm.v7i2.887. eCollection 2018.

8.

Extensively drug-resistant tuberculosis in South Africa: genomic evidence supporting transmission in communities.

Auld SC, Shah NS, Mathema B, Brown TS, Ismail N, Omar SV, Brust JCM, Nelson KN, Allana S, Campbell A, Mlisana K, Moodley P, Gandhi NR.

Eur Respir J. 2018 Oct 18;52(4). pii: 1800246. doi: 10.1183/13993003.00246-2018. Print 2018 Oct.

PMID:
30115614
9.

Synthesis and Structural Elucidation of Novel Benzothiazole Derivatives as Anti-tubercular Agents: In-silico Screening for Possible Target Identification.

Venugopala KN, Chandrashekharappa S, Pillay M, Bhandary S, Kandeel M, Mahomoodally FM, Morsy MA, Chopra D, Aldhubiab BE, Attimarad M, Alwassil OI, Harsha S, Mlisana K, Odhav B.

Med Chem. 2019;15(3):311-326. doi: 10.2174/1573406414666180703121815.

PMID:
29968540
10.

Spatial Patterns of Extensively Drug-Resistant Tuberculosis Transmission in KwaZulu-Natal, South Africa.

Nelson KN, Shah NS, Mathema B, Ismail N, Brust JCM, Brown TS, Auld SC, Omar SV, Morris N, Campbell A, Allana S, Moodley P, Mlisana K, Gandhi NR.

J Infect Dis. 2018 Nov 5;218(12):1964-1973. doi: 10.1093/infdis/jiy394. Erratum in: J Infect Dis. 2019 Jan 9;219(3):509.

PMID:
29961879
11.

Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries.

Garrett NJ, Osman F, Maharaj B, Naicker N, Gibbs A, Norman E, Samsunder N, Ngobese H, Mitchev N, Singh R, Abdool Karim SS, Kharsany ABM, Mlisana K, Rompalo A, Mindel A.

PLoS One. 2018 Apr 24;13(4):e0196209. doi: 10.1371/journal.pone.0196209. eCollection 2018.

12.

Improved Survival and Cure Rates With Concurrent Treatment for Multidrug-Resistant Tuberculosis-Human Immunodeficiency Virus Coinfection in South Africa.

Brust JCM, Shah NS, Mlisana K, Moodley P, Allana S, Campbell A, Johnson BA, Master I, Mthiyane T, Lachman S, Larkan LM, Ning Y, Malik A, Smith JP, Gandhi NR.

Clin Infect Dis. 2018 Apr 3;66(8):1246-1253. doi: 10.1093/cid/cix1125.

13.

Spatial distribution of extensively drug-resistant tuberculosis (XDR TB) patients in KwaZulu-Natal, South Africa.

Kapwata T, Morris N, Campbell A, Mthiyane T, Mpangase P, Nelson KN, Allana S, Brust JCM, Moodley P, Mlisana K, Gandhi NR, Shah NS.

PLoS One. 2017 Oct 13;12(10):e0181797. doi: 10.1371/journal.pone.0181797. eCollection 2017.

14.

Protocol for a randomised controlled implementation trial of point-of-care viral load testing and task shifting: the Simplifying HIV TREAtment and Monitoring (STREAM) study.

Dorward J, Garrett N, Quame-Amaglo J, Samsunder N, Ngobese H, Ngomane N, Moodley P, Mlisana K, Schaafsma T, Donnell D, Barnabas R, Naidoo K, Abdool Karim S, Celum C, Drain PK.

BMJ Open. 2017 Sep 27;7(9):e017507. doi: 10.1136/bmjopen-2017-017507.

15.

Detecting Mycobacterium tuberculosis using the loop-mediated isothermal amplification test in South Africa.

Reddy S, Ntoyanto S, Sakadavan Y, Reddy T, Mahomed S, Dlamini M, Spooner B, Ramjee G, Coutsoudis A, Ngomane N, Naidoo K, Mlisana K, Kiepiela P.

Int J Tuberc Lung Dis. 2017 Oct 1;21(10):1154-1160. doi: 10.5588/ijtld.16.0863.

PMID:
28911361
16.

Failure of BACTEC™ MGIT 960™ to detect Mycobacterium tuberculosis complex within a 42-day incubation period.

Mahomed S, Dlamini-Mvelase NR, Dlamini M, Mlisana K.

Afr J Lab Med. 2017 Apr 26;6(1):537. doi: 10.4102/ajlm.v6i1.537. eCollection 2017.

17.

Evaluation of the BioFire® FilmArray® Blood Culture Identification Panel on positive blood cultures in a regional hospital laboratory in KwaZulu-Natal.

Fhooblall M, Nkwanyana F, Mlisana KP.

Afr J Lab Med. 2016 Sep 30;5(1):411. doi: 10.4102/ajlm.v5i1.411. eCollection 2016.

18.

Rapid Accurate Identification of Tuberculous Meningitis Among South African Children Using a Novel Clinical Decision Tool.

Goenka A, Jeena PM, Mlisana K, Solomon T, Spicer K, Stephenson R, Verma A, Dhada B, Griffiths MJ.

Pediatr Infect Dis J. 2018 Mar;37(3):229-234. doi: 10.1097/INF.0000000000001726.

19.

Molecular Characterization of Corynebacterium diphtheriae Outbreak Isolates, South Africa, March-June 2015.

du Plessis M, Wolter N, Allam M, de Gouveia L, Moosa F, Ntshoe G, Blumberg L, Cohen C, Smith M, Mutevedzi P, Thomas J, Horne V, Moodley P, Archary M, Mahabeer Y, Mahomed S, Kuhn W, Mlisana K, McCarthy K, von Gottberg A.

Emerg Infect Dis. 2017 Aug;23(8):1308-1315. doi: 10.3201/eid2308.162039.

20.

Polymorphisms in the vitamin D receptor gene are associated with reduced rate of sputum culture conversion in multidrug-resistant tuberculosis patients in South Africa.

Magee MJ, Sun YV, Brust JCM, Shah NS, Ning Y, Allana S, Campbell A, Hui Q, Mlisana K, Moodley P, Gandhi NR.

PLoS One. 2017 Jul 10;12(7):e0180916. doi: 10.1371/journal.pone.0180916. eCollection 2017.

21.

An isolated outbreak of diphtheria in South Africa, 2015 - Erratum.

Mahomed S, Archary M, Mutevedzi P, Mahabeer Y, Govender P, Ntshoe G, Kuhn W, Thomas J, Olowolagba A, Blumberg L, McCarthy K, Mlisana K, Du Plessis M, Von Gottberg A, Moodley P.

Epidemiol Infect. 2018 Apr;146(5):664. doi: 10.1017/S0950268817001376. Epub 2017 Jul 3. No abstract available.

PMID:
28669370
22.

Molecular modeling studies and anti-TB activity of trisubstituted indolizine analogues; molecular docking and dynamic inputs.

Khedr MA, Pillay M, Chandrashekharappa S, Chopra D, Aldhubiab BE, Attimarad M, Alwassil OI, Mlisana K, Odhav B, Venugopala KN.

J Biomol Struct Dyn. 2018 Jun;36(8):2163-2178. doi: 10.1080/07391102.2017.1345325. Epub 2017 Aug 14.

PMID:
28657441
23.

An isolated outbreak of diphtheria in South Africa, 2015.

Mahomed S, Archary M, Mutevedzi P, Mahabeer Y, Govender P, Ntshoe G, Kuhn W, Thomas J, Olowolagba A, Blumberg L, McCarthy K, Mlisana K, DU Plessis M, VON Gottberg A, Moodley P.

Epidemiol Infect. 2017 Jul;145(10):2100-2108. doi: 10.1017/S0950268817000851. Epub 2017 May 8. Erratum in: Epidemiol Infect. 2018 Apr;146(5):664.

PMID:
28478776
24.

An unusual case of thoracic empyema caused by Granulicatella elegans (nutritionally variant streptococci) in a patient with pulmonary tuberculosis and human immunodeficiency virus infection.

Mvelase NR, Marajh K, Hattingh O, Mlisana KP.

JMM Case Rep. 2016 Oct 27;3(5):e005058. doi: 10.1099/jmmcr.0.005058. eCollection 2016 Oct.

25.

Analysis of clinical and microbiological data on Acinetobacter baumannii strains assist the preauthorization of antibiotics at the patient level for an effective antibiotic stewardship program.

Swe Swe-Han K, Mlisana KP, Pillay M.

J Infect Public Health. 2017 Sep - Oct;10(5):608-616. doi: 10.1016/j.jiph.2017.01.014. Epub 2017 Feb 23.

26.

pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia.

Allana S, Shashkina E, Mathema B, Bablishvili N, Tukvadze N, Shah NS, Kempker RR, Blumberg HM, Moodley P, Mlisana K, Brust JC, Gandhi NR.

Emerg Infect Dis. 2017 Mar;23(3):491-495. doi: 10.3201/eid2303.161034.

27.

Transmission of Extensively Drug-Resistant Tuberculosis in South Africa.

Shah NS, Auld SC, Brust JC, Mathema B, Ismail N, Moodley P, Mlisana K, Allana S, Campbell A, Mthiyane T, Morris N, Mpangase P, van der Meulen H, Omar SV, Brown TS, Narechania A, Shaskina E, Kapwata T, Kreiswirth B, Gandhi NR.

N Engl J Med. 2017 Jan 19;376(3):243-253. doi: 10.1056/NEJMoa1604544.

28.

Metabolic Syndrome After HIV Acquisition in South African Women.

Sobieszczyk ME, Werner L, Mlisana K, Naicker N, Feinstein A, Gray CM, Masson L, Passmore JS, Williamson C, Abdool Karim Q, Abdool Karim SS, Garrett NJ.

J Acquir Immune Defic Syndr. 2016 Dec 1;73(4):438-445.

PMID:
27391387
29.

Design, synthesis, and characterization of (1-(4-aryl)- 1H-1,2,3-triazol-4-yl)methyl, substituted phenyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates against Mycobacterium tuberculosis.

Venugopala KN, Dharma Rao GB, Bhandary S, Pillay M, Chopra D, Aldhubiab BE, Attimarad M, Alwassil OI, Harsha S, Mlisana K.

Drug Des Devel Ther. 2016 Aug 25;10:2681-90. doi: 10.2147/DDDT.S109760. eCollection 2016.

30.

Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants.

Churchyard G, Mlisana K, Karuna S, Williamson AL, Williamson C, Morris L, Tomaras GD, De Rosa SC, Gilbert PB, Gu N, Yu C, Mkhize NN, Hermanus T, Allen M, Pensiero M, Barnett SW, Gray G, Bekker LG, Montefiori DC, Kublin J, Corey L.

PLoS One. 2016 Sep 1;11(9):e0161753. doi: 10.1371/journal.pone.0161753. eCollection 2016.

31.

Antimicrobial stewardship in South Africa: a fruitful endeavour.

Ramsamy Y, Muckart DJJ, Mlisana KP.

Lancet Infect Dis. 2016 Sep;16(9):982-983. doi: 10.1016/S1473-3099(16)30052-4. Epub 2016 Jun 14. No abstract available. Erratum in: Lancet Infect Dis. 2016 Dec;16(12):1324.

PMID:
27312578
32.

Association of Polymorphisms in the Regulatory Region of the Cyclophilin a Gene (PPIA) with Gene Expression and HIV/AIDS Disease Progression.

Madlala P, Singh R, An P, Werner L, Mlisana K, Abdool Karim SS, Winkler CA, Ndungʼu T.

J Acquir Immune Defic Syndr. 2016 Aug 15;72(5):465-73. doi: 10.1097/QAI.0000000000001028.

33.

Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.

Desjardins CA, Cohen KA, Munsamy V, Abeel T, Maharaj K, Walker BJ, Shea TP, Almeida DV, Manson AL, Salazar A, Padayatchi N, O'Donnell MR, Mlisana KP, Wortman J, Birren BW, Grosset J, Earl AM, Pym AS.

Nat Genet. 2016 May;48(5):544-51. doi: 10.1038/ng.3548. Epub 2016 Apr 11.

34.

Empirical antimicrobial therapy for probable v. directed therapy for possible ventilator-associated pneumonia in critically injured patients.

Ramsamy Y, Muckart DJ, Bruce JL, Hardcastle TC, Han KS, Mlisana KP.

S Afr Med J. 2016 Jan 6;106(2):196-200. doi: 10.7196/SAMJ.2016.v106i2.9870.

PMID:
26821903
35.

Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.

Naranbhai V, de Assis Rosa D, Werner L, Moodley R, Hong H, Kharsany A, Mlisana K, Sibeko S, Garrett N, Chopera D, Carr WH, Abdool Karim Q, Hill AV, Abdool Karim SS, Altfeld M, Gray CM, Ndung'u T.

BMC Infect Dis. 2016 Jan 25;16:27. doi: 10.1186/s12879-016-1361-1.

36.
37.

Inflammatory cytokine biomarkers to identify women with asymptomatic sexually transmitted infections and bacterial vaginosis who are at high risk of HIV infection.

Masson L, Arnold KB, Little F, Mlisana K, Lewis DA, Mkhize N, Gamieldien H, Ngcapu S, Johnson L, Lauffenburger DA, Abdool Karim Q, Abdool Karim SS, Passmore JA.

Sex Transm Infect. 2016 May;92(3):186-93. doi: 10.1136/sextrans-2015-052072. Epub 2015 Oct 28.

PMID:
26511781
38.

Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal.

Cohen KA, Abeel T, Manson McGuire A, Desjardins CA, Munsamy V, Shea TP, Walker BJ, Bantubani N, Almeida DV, Alvarado L, Chapman SB, Mvelase NR, Duffy EY, Fitzgerald MG, Govender P, Gujja S, Hamilton S, Howarth C, Larimer JD, Maharaj K, Pearson MD, Priest ME, Zeng Q, Padayatchi N, Grosset J, Young SK, Wortman J, Mlisana KP, O'Donnell MR, Birren BW, Bishai WR, Pym AS, Earl AM.

PLoS Med. 2015 Sep 29;12(9):e1001880. doi: 10.1371/journal.pmed.1001880. eCollection 2015 Sep.

39.

Continued Follow-Up of Phambili Phase 2b Randomized HIV-1 Vaccine Trial Participants Supports Increased HIV-1 Acquisition among Vaccinated Men.

Moodie Z, Metch B, Bekker LG, Churchyard G, Nchabeleng M, Mlisana K, Laher F, Roux S, Mngadi K, Innes C, Mathebula M, Allen M, Bentley C, Gilbert PB, Robertson M, Kublin J, Corey L, Gray GE.

PLoS One. 2015 Sep 14;10(9):e0137666. doi: 10.1371/journal.pone.0137666. eCollection 2015.

40.

High Prevalence of inhA Promoter Mutations among Patients with Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa.

Niehaus AJ, Mlisana K, Gandhi NR, Mathema B, Brust JC.

PLoS One. 2015 Sep 2;10(9):e0135003. doi: 10.1371/journal.pone.0135003. eCollection 2015.

41.

Relationship between female genital tract infections, mucosal interleukin-17 production and local T helper type 17 cells.

Masson L, Salkinder AL, Olivier AJ, McKinnon LR, Gamieldien H, Mlisana K, Scriba TJ, Lewis DA, Little F, Jaspan HB, Ronacher K, Denny L, Abdool Karim SS, Passmore JA.

Immunology. 2015 Dec;146(4):557-67. doi: 10.1111/imm.12527. Epub 2015 Oct 23.

42.

Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa.

Lim JR, Gandhi NR, Mthiyane T, Mlisana K, Moodley J, Jaglal P, Ramdin N, Brust JC, Ismail N, Rustomjee R, Shah NS.

PLoS One. 2015 Jul 6;10(7):e0132076. doi: 10.1371/journal.pone.0132076. eCollection 2015.

43.

Innate Antibacterial Activity in Female Genital Tract Secretions Is Associated with Increased Risk of HIV Acquisition.

Pellett Madan R, Masson L, Tugetman J, Werner L, Grobler A, Mlisana K, Lo Y, Che D, Arnold KB, Abdool Karim SS, Passmore JA, Herold BC.

AIDS Res Hum Retroviruses. 2015 Nov;31(11):1153-9. doi: 10.1089/AID.2015.0011. Epub 2015 Jul 14.

44.

Lower concentrations of chemotactic cytokines and soluble innate factors in the lower female genital tract associated with the use of injectable hormonal contraceptive.

Ngcapu S, Masson L, Sibeko S, Werner L, McKinnon LR, Mlisana K, Shey M, Samsunder N, Karim SA, Karim QA, Passmore JA.

J Reprod Immunol. 2015 Aug;110:14-21. doi: 10.1016/j.jri.2015.03.007. Epub 2015 Apr 22.

45.

Primary Capreomycin Resistance Is Common and Associated With Early Mortality in Patients With Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa.

OʼDonnell MR, Pillay M, Pillay M, Werner L, Master I, Wolf A, Mathema B, Coovadia YM, Mlisana K, Horsburgh CR, Padayatchi N.

J Acquir Immune Defic Syndr. 2015 Aug 15;69(5):536-43. doi: 10.1097/QAI.0000000000000650.

46.

Novel imidazo[2,1-b]-1,3,4-thiadiazoles as promising antifungal agents against clinical isolate of Cryptococcus neoformans.

Alwan WS, Karpoormath R, Palkar MB, Patel HM, Rane RA, Shaikh MS, Kajee A, Mlisana KP.

Eur J Med Chem. 2015 May 5;95:514-25. doi: 10.1016/j.ejmech.2015.03.021. Epub 2015 Mar 12.

PMID:
25847769
47.

Demonstrating the efficacy of the FoneAstra pasteurization monitor for human milk pasteurization in resource-limited settings.

Naicker M, Coutsoudis A, Israel-Ballard K, Chaudhri R, Perin N, Mlisana K.

Breastfeed Med. 2015 Mar;10(2):107-12. doi: 10.1089/bfm.2014.0125. Epub 2015 Feb 10.

48.

Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting.

Naicker N, Kharsany AB, Werner L, van Loggerenberg F, Mlisana K, Garrett N, Abdool Karim SS.

AIDS Behav. 2015 Jul;19(7):1305-16. doi: 10.1007/s10461-015-1002-5.

49.

Comparison of Etests and Vitek 2 ® to broth microdilution for the susceptibility testing of Cryptococcus neoformans.

Mahabeer Y, Chang CC, Naidu D, Dorasamy A, Lewin S, Ndung'u T, Moosa MY, French M, Mlisana K, Coovadia Y.

Diagn Microbiol Infect Dis. 2014 Dec;80(4):294-8. doi: 10.1016/j.diagmicrobio.2014.09.006. Epub 2014 Sep 16.

PMID:
25277745
50.

Effects of introducing Xpert MTB/RIF test on multi-drug resistant tuberculosis diagnosis in KwaZulu-Natal South Africa.

Dlamini-Mvelase NR, Werner L, Phili R, Cele LP, Mlisana KP.

BMC Infect Dis. 2014 Aug 16;14:442. doi: 10.1186/1471-2334-14-442.

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