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Items: 1 to 50 of 177

1.

Experimental validation of stochastic microdosimetric kinetic model for multi-ion therapy treatment planning with helium-, carbon-, oxygen-, and neon-ion beams.

Inaniwa T, Suzuki M, Hyun Lee S, Mizushima K, Iwata Y, Kanematsu N, Shirai T.

Phys Med Biol. 2020 Feb 12;65(4):045005. doi: 10.1088/1361-6560/ab6eba.

PMID:
31968318
2.

Promotion of wound healing by acetate in murine colonic epithelial cell via c-Jun N-terminal kinase activation.

Nakano T, Uchiyama K, Ushiroda C, Kashiwagi S, Toyokawa Y, Mizushima K, Inoue K, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Naito Y, Itoh Y.

J Gastroenterol Hepatol. 2020 Jan 21. doi: 10.1111/jgh.14987. [Epub ahead of print]

PMID:
31961456
3.

Magnetization switching of a perpendicular nanomagnet induced by vertical nonlocal injection of pure spin current.

Suto H, Nagasawa T, Kanao T, Yamada K, Mizushima K.

Sci Rep. 2019 Dec 20;9(1):19543. doi: 10.1038/s41598-019-56082-x.

4.

Nuclear-interaction correction for patient dose calculations in treatment planning of helium-, carbon-, oxygen-, and neon-ion beams.

Inaniwa T, Lee SH, Mizushima K, Sakata D, Iwata Y, Kanematsu N, Shirai T.

Phys Med Biol. 2020 Jan 17;65(2):025004. doi: 10.1088/1361-6560/ab5fee.

PMID:
31816612
5.

Zinc deficiency activates IL-23/Th17 axis to aggravate experimental colitis in mice.

Higashimura Y, Takagi T, Naito Y, Uchiyama K, Mizushima K, Tanaka M, Hamaguchi M, Itoh Y.

J Crohns Colitis. 2019 Nov 30. pii: jjz193. doi: 10.1093/ecco-jcc/jjz193. [Epub ahead of print]

PMID:
31783404
6.

Higher Levels of Streptococcus in Upper Gastrointestinal Mucosa Associated with Symptoms in Patients with Functional Dyspepsia.

Fukui A, Takagi T, Naito Y, Inoue R, Kashiwagi S, Mizushima K, Inada Y, Inoue K, Harusato A, Dohi O, Okayama T, Katada K, Kamada K, Uchiyama K, Ishikawa T, Handa O, Itoh Y, Nakagawa M.

Digestion. 2020;101(1):38-45. doi: 10.1159/000504090. Epub 2019 Nov 21.

PMID:
31752012
7.

High-Fat Diet Causes Constipation in Mice via Decreasing Colonic Mucus.

Mukai R, Handa O, Naito Y, Takayama S, Suyama Y, Ushiroda C, Majima A, Hirai Y, Mizushima K, Okayama T, Katada K, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Itoh Y.

Dig Dis Sci. 2019 Nov 14. doi: 10.1007/s10620-019-05954-3. [Epub ahead of print]

PMID:
31728788
8.

15-Deoxy-Δ12,14-prostaglandin J2 ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction.

Takagi T, Naito Y, Mizushima K, Hirai Y, Kamada K, Uchiyama K, Handa O, Ishikawa T, Itoh Y.

Arch Biochem Biophys. 2019 Nov 30;677:108183. doi: 10.1016/j.abb.2019.108183. Epub 2019 Nov 5.

PMID:
31704099
9.

Gut microbiota differences in elderly subjects between rural city Kyotango and urban city Kyoto: an age-gender-matched study.

Naito Y, Takagi T, Inoue R, Kashiwagi S, Mizushima K, Tsuchiya S, Itoh Y, Okuda K, Tsujimoto Y, Adachi A, Maruyama N, Oda Y, Matoba S.

J Clin Biochem Nutr. 2019 Sep;65(2):125-131. doi: 10.3164/jcbn.19-26. Epub 2019 Aug 9.

10.

Effects of Magnetic Field Applied Just Before, During or Immediately after Carbon-Ion Beam Irradiation on its Biological Effectiveness.

Inaniwa T, Suzuki M, Sato S, Muramatsu M, Mizushima K, Iwata Y, Kanematsu N, Shirai T, Noda K.

Radiat Res. 2019 Dec;192(6):662-665. doi: 10.1667/RR15446.1. Epub 2019 Sep 27.

PMID:
31560639
11.

Green tea polyphenol (epigallocatechin-3-gallate) improves gut dysbiosis and serum bile acids dysregulation in high-fat diet-fed mice.

Ushiroda C, Naito Y, Takagi T, Uchiyama K, Mizushima K, Higashimura Y, Yasukawa Z, Okubo T, Inoue R, Honda A, Matsuzaki Y, Itoh Y.

J Clin Biochem Nutr. 2019 Jul;65(1):34-46. doi: 10.3164/jcbn.18-116. Epub 2019 Apr 6.

12.

Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin-4 Deletion Against Ischemia/Reperfusion Injury.

Nishi M, Ogata T, Cannistraci CV, Ciucci S, Nakanishi N, Higuchi Y, Sakamoto A, Tsuji Y, Mizushima K, Matoba S.

J Am Heart Assoc. 2019 Aug 6;8(15):e012047. doi: 10.1161/JAHA.119.012047. Epub 2019 Jul 31.

13.

Gene expression analysis of conjunctival epithelium of patients with Stevens-Johnson syndrome in the chronic stage.

Ueta M, Sotozono C, Nishigaki H, Ohsako S, Yokoi N, Mizushima K, Naito Y, Kinoshita S.

BMJ Open Ophthalmol. 2019 Jun 16;4(1):e000254. doi: 10.1136/bmjophth-2018-000254. eCollection 2019.

14.

Secreted protein acidic and rich in cysteine (SPARC) improves glucose tolerance via AMP-activated protein kinase activation.

Aoi W, Hirano N, Lassiter DG, Björnholm M, Chibalin AV, Sakuma K, Tanimura Y, Mizushima K, Takagi T, Naito Y, Zierath JR, Krook A.

FASEB J. 2019 Sep;33(9):10551-10562. doi: 10.1096/fj.201900453R. Epub 2019 Jun 21.

PMID:
31225998
15.

Administration of live, but not inactivated, Faecalibacterium prausnitzii has a preventive effect on dextran sodium sulfate‑induced colitis in mice.

Kawade Y, Sakai M, Okamori M, Morita M, Mizushima K, Ueda T, Takagi T, Naito Y, Itoh Y, Shimada T.

Mol Med Rep. 2019 Jul;20(1):25-32. doi: 10.3892/mmr.2019.10234. Epub 2019 May 14.

PMID:
31115531
16.

Combined treatment of dipeptidyl peptidase-4 inhibitor and exercise training improves lipid profile in KK/Ta mice.

Tanimura Y, Aoi W, Mizushima K, Higashimura Y, Naito Y.

Exp Physiol. 2019 Jul;104(7):1051-1060. doi: 10.1113/EP087449. Epub 2019 May 22.

PMID:
31020720
17.

Mucosa-Associated Microbiota in the Gastrointestinal Tract of Healthy Japanese Subjects.

Kashiwagi S, Naito Y, Inoue R, Takagi T, Nakano T, Inada Y, Fukui A, Katada K, Mizushima K, Kamada K, Uchiyama K, Handa O, Ishikawa T, Itoh Y.

Digestion. 2019 Feb 5:1-14. doi: 10.1159/000496102. [Epub ahead of print]

PMID:
30721900
18.

Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice.

Takagi T, Homma T, Fujii J, Shirasawa N, Yoriki H, Hotta Y, Higashimura Y, Mizushima K, Hirai Y, Katada K, Uchiyama K, Naito Y, Itoh Y.

Free Radic Biol Med. 2019 Apr;134:153-164. doi: 10.1016/j.freeradbiomed.2018.12.024. Epub 2018 Dec 19.

PMID:
30578917
19.

Heme oxygenase-1 prevents murine intestinal inflammation.

Takagi T, Naito Y, Mizushima K, Hirai Y, Harusato A, Okayama T, Katada K, Kamada K, Uchiyama K, Handa O, Ishikawa T, Itoh Y.

J Clin Biochem Nutr. 2018 Nov;63(3):169-174. doi: 10.3164/jcbn.17-133. Epub 2018 Jul 12.

20.

Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal-regulated kinase and Rho signaling.

Toyokawa Y, Takagi T, Uchiyama K, Mizushima K, Inoue K, Ushiroda C, Kashiwagi S, Nakano T, Hotta Y, Tanaka M, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Ishikawa T, Handa O, Konishi H, Naito Y, Itoh Y.

J Gastroenterol Hepatol. 2019 Jul;34(7):1193-1200. doi: 10.1111/jgh.14532. Epub 2018 Nov 22.

PMID:
30394577
21.

Transforming growth factor β1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 4.

Hotta Y, Uchiyama K, Takagi T, Kashiwagi S, Nakano T, Mukai R, Toyokawa Y, Yasuda T, Ueda T, Suyama Y, Murakami T, Tanaka M, Majima A, Doi T, Hirai Y, Mizushima K, Morita M, Higashimura Y, Inoue K, Fukui A, Okayama T, Katada K, Kamada K, Handa O, Ishikawa T, Naito Y, Itoh Y.

Biochem Biophys Res Commun. 2018 Nov 30;506(3):557-562. doi: 10.1016/j.bbrc.2018.10.116. Epub 2018 Oct 23.

PMID:
30361098
22.

Correction to: Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects.

Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, Tsuchiya S, Dohi O, Yoshida N, Kamada K, Ishikawa T, Handa O, Konishi H, Okuda K, Tsujimoto Y, Ohnogi H, Itoh Y.

J Gastroenterol. 2019 Jan;54(1):96-98. doi: 10.1007/s00535-018-1504-9.

PMID:
30191312
23.

Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects.

Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, Tsuchiya S, Dohi O, Yoshida N, Kamada K, Ishikawa T, Handa O, Konishi H, Okuda K, Tsujimoto Y, Ohnogi H, Itoh Y.

J Gastroenterol. 2019 Jan;54(1):53-63. doi: 10.1007/s00535-018-1488-5. Epub 2018 Jun 20. Erratum in: J Gastroenterol. 2018 Sep 6;:.

PMID:
29926167
24.

Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

Higashimura Y, Baba Y, Inoue R, Takagi T, Uchiyama K, Mizushima K, Hirai Y, Ushiroda C, Tanaka Y, Naito Y.

Med Gas Res. 2018 Apr 18;8(1):6-11. doi: 10.4103/2045-9912.229597. eCollection 2018 Jan-Mar.

25.

Carbon monoxide ameliorates murine T-cell-dependent colitis through the inhibition of Th17 differentiation.

Takagi T, Naito Y, Tanaka M, Mizushima K, Ushiroda C, Toyokawa Y, Uchiyama K, Hamaguchi M, Handa O, Itoh Y.

Free Radic Res. 2018 Dec;52(11-12):1328-1335. doi: 10.1080/10715762.2018.1470327. Epub 2018 May 16.

PMID:
29695203
26.

Selected reaction monitoring for colorectal cancer diagnosis using a set of five serum peptides identified by BLOTCHIP®-MS analysis.

Uchiyama K, Naito Y, Yagi N, Mizushima K, Higashimura Y, Hirai Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Nonaka D, Asada K, Lee LJ, Tanaka K, Kuriu Y, Nakanishi M, Otsuji E, Itoh Y.

J Gastroenterol. 2018 Nov;53(11):1179-1185. doi: 10.1007/s00535-018-1448-0. Epub 2018 Mar 1.

PMID:
29497816
27.

The influence of long-term use of proton pump inhibitors on the gut microbiota: an age-sex-matched case-control study.

Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, Tsuchiya S, Okayama T, Dohi O, Yoshida N, Kamada K, Ishikawa T, Handa O, Konishi H, Okuda K, Tsujimoto Y, Ohnogi H, Itoh Y.

J Clin Biochem Nutr. 2018 Jan;62(1):100-105. doi: 10.3164/jcbn.17-78. Epub 2017 Dec 12.

28.

Lactobacillus brevis KB290 With Vitamin A Ameliorates Murine Intestinal Inflammation Associated With the Increase of CD11c+ Macrophage/CD103- Dendritic Cell Ratio.

Fuke N, Takagi T, Higashimura Y, Tsuji T, Umeda R, Mizushima K, Tanaka M, Suganuma H, Aizawa K, Yajima N, Naito Y.

Inflamm Bowel Dis. 2018 Jan 18;24(2):317-331. doi: 10.1093/ibd/izx003.

PMID:
29361084
29.

The protective effect of orally administered redox nanoparticle on intestinal ischemia-reperfusion injury in mice.

Ueda T, Takagi T, Katada K, Iida T, Mizushima K, Dohi O, Okayama T, Yoshida N, Kamada K, Uchiyama K, Handa O, Ishikawa T, Konishi H, Naito Y, Nagasaki Y, Itoh Y.

Biochem Biophys Res Commun. 2018 Jan 8;495(2):2044-2049. doi: 10.1016/j.bbrc.2017.11.204. Epub 2017 Dec 2.

PMID:
29198710
30.

Zero-dc-field rotation-direction-dependent magnetization switching induced by a circularly polarized microwave magnetic field.

Suto H, Kanao T, Nagasawa T, Mizushima K, Sato R.

Sci Rep. 2017 Oct 23;7(1):13804. doi: 10.1038/s41598-017-13770-w.

31.

Rebamipide upregulates mucin secretion of intestinal goblet cells via Akt phosphorylation.

Yasuda-Onozawa Y, Handa O, Naito Y, Ushiroda C, Suyama Y, Toyokawa Y, Murakami T, Yasuda T, Ueda T, Majima A, Hotta Y, Doi T, Tanaka M, Horii Y, Higashimura Y, Mizushima K, Morita M, Uehara Y, Horie H, Fukui A, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y.

Mol Med Rep. 2017 Dec;16(6):8216-8222. doi: 10.3892/mmr.2017.7647. Epub 2017 Sep 28.

PMID:
28983630
32.

Agaro-Oligosaccharides Regulate Gut Microbiota and Adipose Tissue Accumulation in Mice.

Higashimura Y, Baba Y, Inoue R, Takagi T, Mizushima K, Ohnogi H, Honda A, Matsuzaki Y, Naito Y.

J Nutr Sci Vitaminol (Tokyo). 2017;63(4):269-276. doi: 10.3177/jnsv.63.269.

33.

Mucocutaneous inflammation in the Ikaros Family Zinc Finger 1-keratin 5-specific transgenic mice.

Ueta M, Hamuro J, Nishigaki H, Nakamura N, Shinomiya K, Mizushima K, Hitomi Y, Tamagawa-Mineoka R, Yokoi N, Naito Y, Tokunaga K, Katoh N, Sotozono C, Kinoshita S.

Allergy. 2018 Feb;73(2):395-404. doi: 10.1111/all.13308. Epub 2017 Oct 16.

PMID:
28914974
34.

Secreted protein acidic and rich in cysteine functions in colitis via IL17A regulation in mucosal CD4+ T cells.

Tanaka M, Takagi T, Naito Y, Uchiyama K, Hotta Y, Toyokawa Y, Ushiroda C, Hirai Y, Aoi W, Higashimura Y, Mizushima K, Okayama T, Katada K, Kamada K, Ishikawa T, Handa O, Itoh Y.

J Gastroenterol Hepatol. 2018 Mar;33(3):671-680. doi: 10.1111/jgh.13842.

PMID:
28582593
35.

Efficient direct conversion of human fibroblasts into myogenic lineage induced by co-transduction with MYCL and MYOD1.

Wakao J, Kishida T, Fumino S, Kimura K, Yamamoto K, Kotani SI, Mizushima K, Naito Y, Yoshikawa T, Tajiri T, Mazda O.

Biochem Biophys Res Commun. 2017 Jun 24;488(2):368-373. doi: 10.1016/j.bbrc.2017.05.059. Epub 2017 May 10.

PMID:
28501623
36.

Novel GBE1 mutation in a Japanese family with adult polyglucosan body disease.

Harigaya Y, Matsukawa T, Fujita Y, Mizushima K, Ishiura H, Mitsui J, Morishita S, Shoji M, Ikeda Y, Tsuji S.

Neurol Genet. 2017 Feb 24;3(2):e138. doi: 10.1212/NXG.0000000000000138. eCollection 2017 Apr. No abstract available.

37.

Dentatorubral-pallidoluysian atrophy (DRPLA) with a small ganglioglioma component containing neurofibrillary tangles and polyglutamine aggregation.

Yamada S, Yamazaki T, Nakata S, Nobusawa S, Ikota H, Ide M, Mizushima K, Harigaya Y, Hirato J, Yokoo H.

Neuropathology. 2017 Aug;37(4):335-340. doi: 10.1111/neup.12365. Epub 2017 Jan 31.

PMID:
28144989
38.

Real-time monitoring of trans-epithelial electrical resistance in cultured intestinal epithelial cells: the barrier protection of water-soluble dietary fiber.

Majima A, Handa O, Naito Y, Suyama Y, Onozawa Y, Higashimura Y, Mizushima K, Morita M, Uehara Y, Horie H, Iida T, Fukui A, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Yasukawa Z, Tokunaga M, Okubo T, Itoh Y.

J Dig Dis. 2017 Mar;18(3):151-159. doi: 10.1111/1751-2980.12456.

PMID:
28139083
39.

The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines.

Doi T, Ishikawa T, Okayama T, Oka K, Mizushima K, Yasuda T, Sakamoto N, Katada K, Kamada K, Uchiyama K, Handa O, Takagi T, Naito Y, Itoh Y.

Oncol Rep. 2017 Mar;37(3):1545-1554. doi: 10.3892/or.2017.5399. Epub 2017 Jan 23.

PMID:
28112370
40.

Changes in Intestinal Motility and Gut Microbiota Composition in a Rat Stress Model.

Murakami T, Kamada K, Mizushima K, Higashimura Y, Katada K, Uchiyama K, Handa O, Takagi T, Naito Y, Itoh Y.

Digestion. 2017;95(1):55-60. doi: 10.1159/000452364. Epub 2017 Jan 5.

PMID:
28052282
41.

Serum metabolomics analysis for early detection of colorectal cancer.

Uchiyama K, Yagi N, Mizushima K, Higashimura Y, Hirai Y, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Kuriu Y, Nakanishi M, Otsuji E, Itoh Y, Naito Y.

J Gastroenterol. 2017 Jun;52(6):677-694. doi: 10.1007/s00535-016-1261-6. Epub 2016 Sep 20.

PMID:
27650200
42.

Reply to the letter from Dr. Miao et al.

Tanimura Y, Aoi W, Takanami Y, Kawai Y, Mizushima K, Naito Y, Yoshikawa T.

Physiol Rep. 2016 Sep;4(17). pii: e12964. doi: 10.14814/phy2.12964. No abstract available.

43.

Partially hydrolysed guar gum ameliorates murine intestinal inflammation in association with modulating luminal microbiota and SCFA.

Takagi T, Naito Y, Higashimura Y, Ushiroda C, Mizushima K, Ohashi Y, Yasukawa Z, Ozeki M, Tokunaga M, Okubo T, Katada K, Kamada K, Uchiyama K, Handa O, Itoh Y, Yoshikawa T.

Br J Nutr. 2016 Oct;116(7):1199-1205. Epub 2016 Sep 8.

PMID:
27604176
44.

Prevention of colitis by controlled oral drug delivery of carbon monoxide.

Steiger C, Uchiyama K, Takagi T, Mizushima K, Higashimura Y, Gutmann M, Hermann C, Botov S, Schmalz HG, Naito Y, Meinel L.

J Control Release. 2016 Oct 10;239:128-36. doi: 10.1016/j.jconrel.2016.08.030. Epub 2016 Aug 27.

PMID:
27578097
45.

A Case of Optic Neuritis Concomitant with Pituitary Tumor During Pregnancy.

Yamaguchi R, Kohga H, Tosaka M, Sekine A, Mizushima K, Harigaya Y, Yoshimoto Y.

World Neurosurg. 2016 Sep;93:488.e1-4. doi: 10.1016/j.wneu.2016.06.103. Epub 2016 Jun 30.

PMID:
27373939
46.

Acute exercise increases fibroblast growth factor 21 in metabolic organs and circulation.

Tanimura Y, Aoi W, Takanami Y, Kawai Y, Mizushima K, Naito Y, Yoshikawa T.

Physiol Rep. 2016 Jun;4(12). pii: e12828. doi: 10.14814/phy2.12828.

47.

Partially hydrolyzed guar gum enhances colonic epithelial wound healing via activation of RhoA and ERK1/2.

Horii Y, Uchiyama K, Toyokawa Y, Hotta Y, Tanaka M, Yasukawa Z, Tokunaga M, Okubo T, Mizushima K, Higashimura Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Naito Y, Itoh Y.

Food Funct. 2016 Jul 13;7(7):3176-83. doi: 10.1039/c6fo00177g.

PMID:
27305660
48.

[Otologic Manifestations in Patients with ANCA Associated Vasculitis-Comparative Analysis among Microscopic Polyangiitis, Granulomatosis with Polyangiitis and Eosinophilic Granulomatosis with Polyangiitis].

Kawashima Y, Noguchi Y, Ito T, Mizushima K, Takahashi M, Kitamura K, Tsutsumi T.

Nihon Jibiinkoka Gakkai Kaiho. 2016 Feb;119(2):110-7. Japanese.

PMID:
27149708
49.

Technical Note: Range verification system using edge detection method for a scintillator and a CCD camera system.

Saotome N, Furukawa T, Hara Y, Mizushima K, Tansho R, Saraya Y, Shirai T, Noda K.

Med Phys. 2016 Apr;43(4):1754. doi: 10.1118/1.4943955.

PMID:
27036572
50.

Propionate Promotes Fatty Acid Oxidation through the Up-Regulation of Peroxisome Proliferator-Activated Receptor α in Intestinal Epithelial Cells.

Higashimura Y, Naito Y, Takagi T, Uchiyama K, Mizushima K, Yoshikawa T.

J Nutr Sci Vitaminol (Tokyo). 2015;61(6):511-5. doi: 10.3177/jnsv.61.511.

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