Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 360

1.

Development of an in silico prediction system of human renal excretion and clearance from chemical structure information incorporating fraction unbound in plasma as a descriptor.

Watanabe R, Ohashi R, Esaki T, Kawashima H, Natsume-Kitatani Y, Nagao C, Mizuguchi K.

Sci Rep. 2019 Dec 11;9(1):18782. doi: 10.1038/s41598-019-55325-1.

PMID:
31827176
2.

Novel anti-flavivirus drugs targeting the nucleolar distribution of core protein.

Tokunaga M, Miyamoto Y, Suzuki T, Otani M, Inuki S, Esaki T, Nagao C, Mizuguchi K, Ohno H, Yoneda Y, Okamoto T, Oka M, Matsuura Y.

Virology. 2019 Nov 29;541:41-51. doi: 10.1016/j.virol.2019.11.015. [Epub ahead of print]

PMID:
31826845
3.

Impact of quality trimming on the efficiency of reads joining and diversity analysis of Illumina paired-end reads in the context of QIIME1 and QIIME2 microbiome analysis frameworks.

Mohsen A, Park J, Chen YA, Kawashima H, Mizuguchi K.

BMC Bioinformatics. 2019 Nov 15;20(1):581. doi: 10.1186/s12859-019-3187-5.

4.

CLINE: a web-tool for the comparison of biological dendrogram structures.

Allendes Osorio RS, Tripathi LP, Mizuguchi K.

BMC Bioinformatics. 2019 Oct 28;20(1):528. doi: 10.1186/s12859-019-3149-y.

5.

The TargetMine Data Warehouse: Enhancement and Updates.

Chen YA, Tripathi LP, Fujiwara T, Kameyama T, Itoh MN, Mizuguchi K.

Front Genet. 2019 Oct 9;10:934. doi: 10.3389/fgene.2019.00934. eCollection 2019.

6.

Actin Cytoskeletal Reorganization Function of JRAB/MICAL-L2 Is Fine-tuned by Intramolecular Interaction between First LIM Zinc Finger and C-terminal Coiled-coil Domains.

Miyake K, Sakane A, Tsuchiya Y, Sagawa I, Tomida Y, Kasahara J, Imoto I, Watanabe S, Higo D, Mizuguchi K, Sasaki T.

Sci Rep. 2019 Sep 5;9(1):12794. doi: 10.1038/s41598-019-49232-8.

7.

Constructing an In Silico Three-Class Predictor of Human Intestinal Absorption With Caco-2 Permeability and Dried-DMSO Solubility.

Esaki T, Ohashi R, Watanabe R, Natsume-Kitatani Y, Kawashima H, Nagao C, Komura H, Mizuguchi K.

J Pharm Sci. 2019 Nov;108(11):3630-3639. doi: 10.1016/j.xphs.2019.07.014. Epub 2019 Jul 25.

PMID:
31351866
8.

Assessing drug target suitability using TargetMine.

Chen YA, Yogo E, Kurihara N, Ohno T, Higuchi C, Rokushima M, Mizuguchi K.

Version 2. F1000Res. 2019 Feb 28 [revised 2019 Jan 1];8:233. doi: 10.12688/f1000research.18214.2. eCollection 2019.

9.

Computational Model To Predict the Fraction of Unbound Drug in the Brain.

Esaki T, Ohashi R, Watanabe R, Natsume-Kitatani Y, Kawashima H, Nagao C, Mizuguchi K.

J Chem Inf Model. 2019 Jul 22;59(7):3251-3261. doi: 10.1021/acs.jcim.9b00180. Epub 2019 Jul 11.

PMID:
31260629
10.

Commentary: How much hydration is really optimal for the kidneys? How will we know?

Mizuguchi KA, Frendl G.

J Thorac Cardiovasc Surg. 2019 May 2. pii: S0022-5223(19)30941-9. doi: 10.1016/j.jtcvs.2019.04.045. [Epub ahead of print] No abstract available.

PMID:
31174858
11.

Data Warehousing with TargetMine for Omics Data Analysis.

Chen YA, Tripathi LP, Mizuguchi K.

Methods Mol Biol. 2019;1986:35-64. doi: 10.1007/978-1-4939-9442-7_3.

PMID:
31115884
12.

Analysis of oral microbiota in Japanese oral cancer patients using 16S rRNA sequencing.

Takahashi Y, Park J, Hosomi K, Yamada T, Kobayashi A, Yamaguchi Y, Iketani S, Kunisawa J, Mizuguchi K, Maeda N, Ohshima T.

J Oral Biosci. 2019 Jun;61(2):120-128. doi: 10.1016/j.job.2019.03.003. Epub 2019 May 16.

PMID:
31109865
13.

B cell-intrinsic MyD88 signaling controls IFN-γ-mediated early IgG2c class switching in mice in response to a particulate adjuvant.

Lee MSJ, Natsume-Kitatani Y, Temizoz B, Fujita Y, Konishi A, Matsuda K, Igari Y, Tsukui T, Kobiyama K, Kuroda E, Onishi M, Marichal T, Ise W, Inoue T, Kurosaki T, Mizuguchi K, Akira S, Ishii KJ, Coban C.

Eur J Immunol. 2019 Sep;49(9):1433-1440. doi: 10.1002/eji.201848084. Epub 2019 May 21.

PMID:
31087643
14.

Commentary: At long last-Cerebral oximetry-based goal directed therapy to prevent postoperative cognitive decline is here.

Aglio LS, Gugino LD, Mizuguchi KA.

J Thorac Cardiovasc Surg. 2019 Apr 4. pii: S0022-5223(19)30744-5. doi: 10.1016/j.jtcvs.2019.03.066. [Epub ahead of print] No abstract available.

PMID:
31053438
15.

Development of Simplified in Vitro P-Glycoprotein Substrate Assay and in Silico Prediction Models To Evaluate Transport Potential of P-Glycoprotein.

Ohashi R, Watanabe R, Esaki T, Taniguchi T, Torimoto-Katori N, Watanabe T, Ogasawara Y, Takahashi T, Tsukimoto M, Mizuguchi K.

Mol Pharm. 2019 May 6;16(5):1851-1863. doi: 10.1021/acs.molpharmaceut.8b01143. Epub 2019 Apr 16.

16.

High-Contrast Facile Imaging with Target-Directing Fluorescent Molecular Rotors, the N3-Modified Thioflavin T Derivatives.

Kataoka Y, Fujita H, Afanaseva A, Nagao C, Mizuguchi K, Kasahara Y, Obika S, Kuwahara M.

Biochemistry. 2019 Feb 12;58(6):493-498. doi: 10.1021/acs.biochem.8b01181. Epub 2019 Jan 7.

PMID:
30595015
17.

Characterization of the Inner and Outer Fiber Layers in the Developing Cerebral Cortex of Gyrencephalic Ferrets.

Saito K, Mizuguchi K, Horiike T, Dinh Duong TA, Shinmyo Y, Kawasaki H.

Cereb Cortex. 2019 Sep 13;29(10):4303-4311. doi: 10.1093/cercor/bhy312.

PMID:
30541068
18.

Predicting Fraction Unbound in Human Plasma from Chemical Structure: Improved Accuracy in the Low Value Ranges.

Watanabe R, Esaki T, Kawashima H, Natsume-Kitatani Y, Nagao C, Ohashi R, Mizuguchi K.

Mol Pharm. 2018 Nov 5;15(11):5302-5311. doi: 10.1021/acs.molpharmaceut.8b00785. Epub 2018 Sep 27.

PMID:
30259749
19.

Data Curation can Improve the Prediction Accuracy of Metabolic Intrinsic Clearance.

Esaki T, Watanabe R, Kawashima H, Ohashi R, Natsume-Kitatani Y, Nagao C, Mizuguchi K.

Mol Inform. 2019 Jan;38(1-2):e1800086. doi: 10.1002/minf.201800086. Epub 2018 Sep 24.

20.

Discovery of biomarkers that diagnose kidney disease progression and novel patient management strategies needed now to prevent progressive kidney disease.

Mizuguchi KA, Shekar P, Frendl G.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2181-2182. doi: 10.1016/j.jtcvs.2018.07.073. Epub 2018 Sep 6. No abstract available.

PMID:
30195592
21.

Anesthetic Management of a Patient With a Leadless Pacemaker Undergoing Cardiac Surgery.

Reddy S, Coletta J, Mizuguchi KA.

J Cardiothorac Vasc Anesth. 2019 Jan;33(1):176-180. doi: 10.1053/j.jvca.2018.05.034. Epub 2018 Jun 1. No abstract available.

PMID:
30054186
22.

Unexpected Color Flow Signal in the Ventricular Septum of a Patient Undergoing Off-Pump Coronary Artery Bypass Grafting Surgery.

Bowker D, Wilhelm BJ, Coletta JM, Mizuguchi KA.

A A Pract. 2018 Dec 1;11(11):318-320. doi: 10.1213/XAA.0000000000000837. No abstract available.

PMID:
30004911
23.

LatY136F knock-in mouse model for human IgG4-related disease.

Yamada K, Zuka M, Ito K, Mizuguchi K, Kakuchi Y, Onoe T, Suzuki Y, Yamagishi M, Izui S, Malissen M, Malissen B, Kawano M.

PLoS One. 2018 Jun 14;13(6):e0198417. doi: 10.1371/journal.pone.0198417. eCollection 2018.

24.

The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer.

Ishimine M, Lee HC, Nakaoka H, Orita H, Kobayashi T, Mizuguchi K, Endo M, Inoue I, Sato K, Yokomizo T.

Dis Markers. 2018 Jan 31;2018:5280736. doi: 10.1155/2018/5280736. eCollection 2018.

25.

Distribution and Morphological Features of Microglia in the Developing Cerebral Cortex of Gyrencephalic Mammals.

Mizuguchi K, Horiike T, Matsumoto N, Ichikawa Y, Shinmyo Y, Kawasaki H.

Neurochem Res. 2018 May;43(5):1075-1085. doi: 10.1007/s11064-018-2520-0. Epub 2018 Apr 3.

PMID:
29616442
26.

Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging.

Jin Y, Takeda Y, Kondo Y, Tripathi LP, Kang S, Takeshita H, Kuhara H, Maeda Y, Higashiguchi M, Miyake K, Morimura O, Koba T, Hayama Y, Koyama S, Nakanishi K, Iwasaki T, Tetsumoto S, Tsujino K, Kuroyama M, Iwahori K, Hirata H, Takimoto T, Suzuki M, Nagatomo I, Sugimoto K, Fujii Y, Kida H, Mizuguchi K, Ito M, Kijima T, Rakugi H, Mekada E, Tachibana I, Kumanogoh A.

Sci Rep. 2018 Mar 23;8(1):5145. doi: 10.1038/s41598-018-23338-x.

27.

Predicting kidney disease progression in patients with acute kidney injury after cardiac surgery.

Mizuguchi KA, Huang CC, Shempp I, Wang J, Shekar P, Frendl G.

J Thorac Cardiovasc Surg. 2018 Jun;155(6):2455-2463.e5. doi: 10.1016/j.jtcvs.2018.01.093. Epub 2018 Feb 17.

PMID:
29548590
28.

An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates.

Masuta Y, Yamamoto T, Natsume-Kitatani Y, Kanuma T, Moriishi E, Kobiyama K, Mizuguchi K, Yasutomi Y, Ishii KJ.

J Immunol. 2018 Mar 15;200(6):2067-2075. doi: 10.4049/jimmunol.1701183. Epub 2018 Feb 5.

29.

Integrating sequence and gene expression information predicts genome-wide DNA-binding proteins and suggests a cooperative mechanism.

Ahmad S, Prathipati P, Tripathi LP, Chen YA, Arya A, Murakami Y, Mizuguchi K.

Nucleic Acids Res. 2018 Jan 9;46(1):54-70. doi: 10.1093/nar/gkx1166.

30.

Essential Role of CARD14 in Murine Experimental Psoriasis.

Tanaka M, Kobiyama K, Honda T, Uchio-Yamada K, Natsume-Kitatani Y, Mizuguchi K, Kabashima K, Ishii KJ.

J Immunol. 2018 Jan 1;200(1):71-81. doi: 10.4049/jimmunol.1700995. Epub 2017 Nov 17.

31.

Quantifying the relative immune cell activation from whole tissue/organ-derived differentially expressed gene data.

Wijaya E, Igarashi Y, Nakatsu N, Haseda Y, Billaud J, Chen YA, Mizuguchi K, Yamada H, Ishii K, Aoshi T.

Sci Rep. 2017 Oct 9;7(1):12847. doi: 10.1038/s41598-017-12970-8.

32.

Peritoneal dialysis-associated catheter infection caused by Mycobacterium abscessus in an elderly patient who was successfully treated with catheter removal.

Hibi A, Kasugai T, Kamiya K, Kamiya K, Ito C, Kominato S, Mizuguchi K, Miura T, Koyama K.

CEN Case Rep. 2017 Nov;6(2):175-179. doi: 10.1007/s13730-017-0270-5. Epub 2017 Aug 9.

33.

Method for preparing DNA from feces in guanidine thiocyanate solution affects 16S rRNA-based profiling of human microbiota diversity.

Hosomi K, Ohno H, Murakami H, Natsume-Kitatani Y, Tanisawa K, Hirata S, Suzuki H, Nagatake T, Nishino T, Mizuguchi K, Miyachi M, Kunisawa J.

Sci Rep. 2017 Jun 28;7(1):4339. doi: 10.1038/s41598-017-04511-0.

34.

Predicting conformational ensembles and genome-wide transcription factor binding sites from DNA sequences.

Andrabi M, Hutchins AP, Miranda-Saavedra D, Kono H, Nussinov R, Mizuguchi K, Ahmad S.

Sci Rep. 2017 Jun 22;7(1):4071. doi: 10.1038/s41598-017-03199-6.

35.

Editorial-Sequences and topology.

Sowdhamini R, Mizuguchi K.

Curr Opin Struct Biol. 2017 Jun;44:vii-viii. doi: 10.1016/j.sbi.2017.05.006. Epub 2017 Jun 4. No abstract available.

PMID:
28587734
36.

A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells.

Yoshimaru T, Ono M, Bando Y, Chen YA, Mizuguchi K, Shima H, Komatsu M, Imoto I, Izumi K, Honda J, Miyoshi Y, Sasa M, Katagiri T.

Nat Commun. 2017 May 30;8:15427. doi: 10.1038/ncomms15427.

37.

Interactive Toxicogenomics: Gene set discovery, clustering and analysis in Toxygates.

Nyström-Persson J, Natsume-Kitatani Y, Igarashi Y, Satoh D, Mizuguchi K.

Sci Rep. 2017 May 3;7(1):1390. doi: 10.1038/s41598-017-01500-1.

38.

Solitary Gastric Metastasis from a Stage IA Serous Ovarian Carcinoma: A Case Report with Literature Review.

Mizuguchi K, Minato H, Yoshida I, Iwadare J, Kayahashi K, Mitani Y, Watanabe K.

Intern Med. 2017;56(8):915-919. doi: 10.2169/internalmedicine.56.7784. Epub 2017 Apr 15. Review.

39.

Network analysis and in silico prediction of protein-protein interactions with applications in drug discovery.

Murakami Y, Tripathi LP, Prathipati P, Mizuguchi K.

Curr Opin Struct Biol. 2017 Jun;44:134-142. doi: 10.1016/j.sbi.2017.02.005. Epub 2017 Mar 30. Review.

PMID:
28364585
40.

Classification of idiopathic interstitial pneumonias using anti-myxovirus resistance-protein 1 autoantibody.

Hamano Y, Kida H, Ihara S, Murakami A, Yanagawa M, Ueda K, Honda O, Tripathi LP, Arai T, Hirose M, Hamasaki T, Yano Y, Kimura T, Kato Y, Takamatsu H, Otsuka T, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Mori M, Nishikawa H, Mizuguchi K, Kijima T, Kitaichi M, Tomiyama N, Inoue Y, Kumanogoh A.

Sci Rep. 2017 Feb 23;7:43201. doi: 10.1038/srep43201.

41.

Computational systems biology for drug discovery: from molecules, structures to networks.

Natsume-Kitatani Y, Mizuguchi K.

Nihon Yakurigaku Zasshi. 2017;149(2):91-95. doi: 10.1254/fpj.149.91. Japanese. No abstract available.

PMID:
28154304
42.

Syndecan-4 as a biomarker to predict clinical outcome for glioblastoma multiforme treated with WT1 peptide vaccine.

Takashima S, Oka Y, Fujiki F, Morimoto S, Nakajima H, Nakae Y, Nakata J, Nishida S, Hosen N, Tatsumi N, Mizuguchi K, Hashimoto N, Oji Y, Tsuboi A, Kumanogoh A, Sugiyama H.

Future Sci OA. 2016 Oct 3;2(4):FSO96. doi: 10.4155/fsoa-2015-0008. eCollection 2016 Dec.

43.

Improved pose and affinity predictions using different protocols tailored on the basis of data availability.

Prathipati P, Nagao C, Ahmad S, Mizuguchi K.

J Comput Aided Mol Des. 2016 Sep;30(9):817-828. Epub 2016 Oct 6.

PMID:
27714493
44.

Cytopathological findings of primary pulmonary Ewing family of tumors with EWSR1 translocation: A case report.

Mizuguchi K, Minato H, Onishi H, Mitani Y, Kawai J.

Thorac Cancer. 2016 Sep;7(5):602-606. doi: 10.1111/1759-7714.12347. Epub 2016 Mar 24.

45.

Conformational plasticity of JRAB/MICAL-L2 provides "law and order" in collective cell migration.

Sakane A, Yoshizawa S, Nishimura M, Tsuchiya Y, Matsushita N, Miyake K, Horikawa K, Imoto I, Mizuguchi C, Saito H, Ueno T, Matsushita S, Haga H, Deguchi S, Mizuguchi K, Yokota H, Sasaki T.

Mol Biol Cell. 2016 Oct 15;27(20):3095-3108. Epub 2016 Aug 31.

47.

Two cases of laparoscopic simultaneous resection of colorectal cancer and synchronous liver metastases in elderly patients.

Ito T, Kushida T, Sakurada M, Maekawa H, Orita H, Mizuguchi K, Sato K.

Int J Surg Case Rep. 2016;26:134-7. doi: 10.1016/j.ijscr.2016.07.030. Epub 2016 Jul 27.

48.

Ligand-induced Ordering of the C-terminal Tail Primes STING for Phosphorylation by TBK1.

Tsuchiya Y, Jounai N, Takeshita F, Ishii KJ, Mizuguchi K.

EBioMedicine. 2016 Jul;9:87-96. doi: 10.1016/j.ebiom.2016.05.039. Epub 2016 Jun 1.

49.

[Respiratory complications in children with Chiari malformation type II associated with myelomeningocele].

Mizuguchi K, Morota N, Kubota M.

No To Hattatsu. 2016 Jan;48(1):25-8. Japanese.

PMID:
27012106
50.

An integrative data analysis platform for gene set analysis and knowledge discovery in a data warehouse framework.

Chen YA, Tripathi LP, Mizuguchi K.

Database (Oxford). 2016 Mar 17;2016. pii: baw009. doi: 10.1093/database/baw009. Print 2016.

Supplemental Content

Loading ...
Support Center