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Items: 1 to 50 of 502

1.

Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.

Takayama K, Negoro R, Yamashita T, Kawai K, Ichikawa M, Mori T, Nakatsu N, Harada K, Ito S, Yamada H, Yamaura Y, Hirata K, Ishida S, Mizuguchi H.

Cell Mol Gastroenterol Hepatol. 2019 Jun 19. pii: S2352-345X(19)30082-7. doi: 10.1016/j.jcmgh.2019.06.004. [Epub ahead of print]

2.

Refractory THSD7A membranous nephropathy with severe asthma related to eosinophilia
.

Suzuki T, Ushimaru S, Uchida D, Watanabe S, Ichikawa D, Koike J, Mizuguchi H, Kawarazaki H, Shibagaki Y.

Clin Nephrol. 2019 Aug;92(2):103-108. doi: 10.5414/CN109751.

PMID:
31198171
3.

Bioluminescence Microplate Assay of Cyanide with Escherichia coli Harboring a Plasmid Responsible for Cyanide-dependent Light Emission in Alginate Microenvironment.

Karatani H, Fuse Y, Mizuguchi H, Monji S, Oyama H, Waku T, Iwasaki M.

Anal Sci. 2019 Jul 10;35(7):821-825. doi: 10.2116/analsci.19N014. Epub 2019 May 17.

4.

miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers.

Sakurai F, Hashimoto R, Inoue C, Wakabayashi K, Tsukamoto T, Imaizumi T, Andres TGM, Sakai E, Itsuki K, Sakamoto N, Wakita T, Mizuguchi H.

Virol J. 2019 May 2;16(1):58. doi: 10.1186/s12985-019-1160-6.

5.

Modeling of Hepatic Drug Metabolism and Responses in CYP2C19 Poor Metabolizer Using Genetically Manipulated Human iPS cells.

Deguchi S, Yamashita T, Igai K, Harada K, Toba Y, Hirata K, Takayama K, Mizuguchi H.

Drug Metab Dispos. 2019 Jun;47(6):632-638. doi: 10.1124/dmd.119.086322. Epub 2019 Apr 8.

PMID:
30962288
6.

Effects of forage feeding on rumen fermentation, plasma metabolites, and hormones in Holstein calves during pre- and postweaning periods1.

Takemura K, Shingu H, Mizuguchi H, Kim YH, Sato S, Kushibiki S.

J Anim Sci. 2019 Apr 29;97(5):2220-2229. doi: 10.1093/jas/skz088.

PMID:
30873561
7.

FGF signal is not required for hepatoblast differentiation of human iPS cells.

Toba Y, Kiso A, Nakamae S, Sakurai F, Takayama K, Mizuguchi H.

Sci Rep. 2019 Mar 6;9(1):3713. doi: 10.1038/s41598-019-40305-2.

8.

Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells.

Kono K, Sawada R, Kuroda T, Yasuda S, Matsuyama S, Matsuyama A, Mizuguchi H, Sato Y.

Sci Rep. 2019 Mar 6;9(1):3630. doi: 10.1038/s41598-018-36848-5.

9.

Pharmaceutical Research for Inherited Metabolic Disorders of the Liver Using Human Induced Pluripotent Stem Cell and Genome Editing Technologies.

Yamashita T, Takayama K, Hori M, Harada-Shiba M, Mizuguchi H.

Biol Pharm Bull. 2019;42(3):312-318. doi: 10.1248/bpb.b18-00544. Review.

10.

Effect of feeding wood kraft pulp on the growth performance, feed digestibility, blood components, and rumen fermentation in Japanese Black fattening steers.

Maeda Y, Nishimura K, Kurosu K, Mizuguchi H, Sato S, Terada F, Kushibiki S.

Anim Sci J. 2019 Apr;90(4):523-532. doi: 10.1111/asj.13182. Epub 2019 Feb 27.

11.

Systemically Administered Reovirus-Induced Downregulation of Hypoxia Inducible Factor-1α in Subcutaneous Tumors.

Hotani T, Mizuguchi H, Sakurai F.

Mol Ther Oncolytics. 2018 Dec 31;12:162-172. doi: 10.1016/j.omto.2018.12.012. eCollection 2019 Mar 29.

12.

Effect of wood kraft pulp feed on digestibility, ruminal characteristics, and milk production performance in lactating dairy cows.

Nishimura K, Kurosu K, Terada F, Mizuguchi H, Sato S, Kushibiki S.

Anim Sci J. 2019 Feb;90(2):189-195. doi: 10.1111/asj.13131. Epub 2018 Dec 16.

13.

LY341495, an mGluR2/3 Antagonist, Regulates the Immunosuppressive Function of Myeloid-Derived Suppressor Cells and Inhibits Melanoma Tumor Growth.

Morikawa N, Tachibana M, Ago Y, Goda H, Sakurai F, Mizuguchi H.

Biol Pharm Bull. 2018;41(12):1866-1869. doi: 10.1248/bpb.b18-00055.

14.

Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies.

Negoro R, Takayama K, Kawai K, Harada K, Sakurai F, Hirata K, Mizuguchi H.

Stem Cell Reports. 2018 Dec 11;11(6):1539-1550. doi: 10.1016/j.stemcr.2018.10.019. Epub 2018 Nov 21.

15.

Polyethylene Glycols for the Dispersion Development of Graphene in an Aqueous Surfactant Solution Studied by Affinity Capillary Electrophoresis.

Takayanagi T, Becchaku Y, Tomiyama Y, Kurashina M, Mizuguchi H.

Anal Sci. 2019 Mar 10;35(3):307-313. doi: 10.2116/analsci.18P433. Epub 2018 Nov 9.

16.

A MicroRNA Derived from Adenovirus Virus-Associated RNAII Promotes Virus Infection via Posttranscriptional Gene Silencing.

Wakabayashi K, Machitani M, Tachibana M, Sakurai F, Mizuguchi H.

J Virol. 2019 Jan 4;93(2). pii: e01265-18. doi: 10.1128/JVI.01265-18. Print 2019 Jan 15.

17.

Effects of irradiation with narrowband-ultraviolet B on up-regulation of histamine H1 receptor mRNA and induction of apoptosis in HeLa cells and nasal mucosa of rats.

Fujii T, Kitamura Y, Mizuguchi H, Okamoto K, Sanada N, Yamada T, Sugiyama M, Michinaga S, Kitayama M, Fukui H, Takeda N.

J Pharmacol Sci. 2018 Sep;138(1):54-62. doi: 10.1016/j.jphs.2018.08.011. Epub 2018 Sep 10.

18.

Effect of wild grape on the signaling of histamine H1 receptor gene expression responsible for the pathogenesis of allergic rhinitis.

Islam R, Mizuguchi H, Shaha A, Nishida K, Yabumoto M, Ikeda H, Fujino H, Kitamura Y, Fukui H, Takeda N.

J Med Invest. 2018;65(3.4):242-250. doi: 10.2152/jmi.65.242.

19.

Optimal human iPS cell culture method for efficient hepatic differentiation.

Matoba N, Yamashita T, Takayama K, Sakurai F, Mizuguchi H.

Differentiation. 2018 Nov - Dec;104:13-21. doi: 10.1016/j.diff.2018.09.005. Epub 2018 Sep 24.

PMID:
30273675
20.

A Flow Cytometry-Based Method to Determine the Titer of Adenoviruses Expressing an Extraneous Gene.

Asada A, Hayakawa H, Yanase N, Abe K, Sakurai F, Mizuguchi H, Urata Y.

Biol Pharm Bull. 2018;41(10):1615-1619. doi: 10.1248/bpb.b18-00316.

21.

Effect of Royal Jelly and Brazilian Green Propolis on the Signaling for Histamine H1 Receptor and Interleukin-9 Gene Expressions Responsible for the Pathogenesis of the Allergic Rhinitis.

Shaha A, Mizuguchi H, Kitamura Y, Fujino H, Yabumoto M, Takeda N, Fukui H.

Biol Pharm Bull. 2018;41(9):1440-1447. doi: 10.1248/bpb.b18-00325.

22.

Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration.

Tomita K, Sakurai F, Iizuka S, Hemmi M, Wakabayashi K, Machitani M, Tachibana M, Katayama K, Kamada H, Mizuguchi H.

Sci Rep. 2018 Aug 17;8(1):12315. doi: 10.1038/s41598-018-30947-z.

23.

A Rapid Enrichment Technique for the Ultratrace Determination of Nickel in Water Samples Using a Nanofiber-composite Membrane Filter.

Mizuguchi H, Ishida R, Kouno Y, Tachibana T, Honda T, Kijima T, Yamamoto Y, Takayanagi T.

Anal Sci. 2018;34(8):907-912. doi: 10.2116/analsci.18P093.

24.

Generation of the Adenovirus Vector-Mediated CRISPR/Cpf1 System and the Application for Primary Human Hepatocytes Prepared from Humanized Mice with Chimeric Liver.

Tsukamoto T, Sakai E, Iizuka S, Taracena-Gándara M, Sakurai F, Mizuguchi H.

Biol Pharm Bull. 2018;41(7):1089-1095. doi: 10.1248/bpb.b18-00222.

25.

Development of a toileting performance assessment test for patients in the early stroke phase.

Takeda E, Yamaguchi T, Mizuguchi H, Fujitani J, Liu M.

Disabil Rehabil. 2018 Jun 29:1-6. doi: 10.1080/09638288.2018.1479455. [Epub ahead of print]

PMID:
29958010
26.

Clinical features of squamous cell lung cancer with anaplastic lymphoma kinase (ALK)-rearrangement: a retrospective analysis and review.

Watanabe J, Togo S, Sumiyoshi I, Namba Y, Suina K, Mizuno T, Kadoya K, Motomura H, Iwai M, Nagaoka T, Sasaki S, Hayashi T, Uekusa T, Abe K, Urata Y, Sakurai F, Mizuguchi H, Kato S, Takahashi K.

Oncotarget. 2018 May 8;9(35):24000-24013. doi: 10.18632/oncotarget.25257. eCollection 2018 May 8.

27.

Human iPS Cell-based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B.

Okamoto R, Takayama K, Akita N, Nagamoto Y, Hosokawa D, Iizuka S, Sakurai F, Suemizu H, Ohashi K, Mizuguchi H.

Cell Transplant. 2018 Feb;27(2):299-309. doi: 10.1177/0963689717751734.

28.

ETV2-TET1/TET2 Complexes Induce Endothelial Cell-Specific Robo4 Expression via Promoter Demethylation.

Tanaka T, Izawa K, Maniwa Y, Okamura M, Okada A, Yamaguchi T, Shirakura K, Maekawa N, Matsui H, Ishimoto K, Hino N, Nakagawa O, Aird WC, Mizuguchi H, Kawabata K, Doi T, Okada Y.

Sci Rep. 2018 Apr 4;8(1):5653. doi: 10.1038/s41598-018-23937-8.

29.

Oncolytic Reovirus Inhibits Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in a TLR3-Dependent Manner.

Katayama Y, Tachibana M, Kurisu N, Oya Y, Terasawa Y, Goda H, Kobiyama K, Ishii KJ, Akira S, Mizuguchi H, Sakurai F.

J Immunol. 2018 Apr 15;200(8):2987-2999. doi: 10.4049/jimmunol.1700435. Epub 2018 Mar 19.

30.

Enrichment of high-functioning human iPS cell-derived hepatocyte-like cells for pharmaceutical research.

Takayama K, Hagihara Y, Toba Y, Sekiguchi K, Sakurai F, Mizuguchi H.

Biomaterials. 2018 Apr;161:24-32. doi: 10.1016/j.biomaterials.2018.01.019. Epub 2018 Jan 18.

PMID:
29421559
31.

Billion-scale production of hepatocyte-like cells from human induced pluripotent stem cells.

Yamashita T, Takayama K, Sakurai F, Mizuguchi H.

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1269-1275. doi: 10.1016/j.bbrc.2018.01.186. Epub 2018 Feb 1.

PMID:
29409945
32.

Generation of safe and therapeutically effective human induced pluripotent stem cell-derived hepatocyte-like cells for regenerative medicine.

Takayama K, Akita N, Mimura N, Akahira R, Taniguchi Y, Ikeda M, Sakurai F, Ohara O, Morio T, Sekiguchi K, Mizuguchi H.

Hepatol Commun. 2017 Oct 12;1(10):1058-1069. doi: 10.1002/hep4.1111. eCollection 2017 Dec.

33.

Nanaomycin A Treatment Promotes Hepatoblast Differentiation from Human iPS Cells.

Nakamae S, Toba Y, Takayama K, Sakurai F, Mizuguchi H.

Stem Cells Dev. 2018 Mar 15;27(6):405-414. doi: 10.1089/scd.2017.0251. Epub 2018 Feb 27.

PMID:
29378471
34.

Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy.

Takayama K, Mizuguchi H.

ACS Chem Biol. 2018 Feb 16;13(2):449-454. doi: 10.1021/acschembio.7b01058. Epub 2018 Jan 12.

PMID:
29327920
35.

Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB.

Machitani M, Sakurai F, Wakabayashi K, Nakatani K, Tachibana M, Kato N, Fujiwara T, Mizuguchi H.

Mol Ther Oncolytics. 2017 Oct 26;7:76-85. doi: 10.1016/j.omto.2017.10.003. eCollection 2017 Dec 15.

36.

Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction.

Nakamori D, Akamine H, Takayama K, Sakurai F, Mizuguchi H.

Sci Rep. 2017 Nov 30;7(1):16675. doi: 10.1038/s41598-017-16856-7.

37.

T Helper 17 Promotes Induction of Antigen-Specific Gut-Mucosal Cytotoxic T Lymphocytes following Adenovirus Vector Vaccination.

Hemmi M, Tachibana M, Fujimoto N, Shoji M, Sakurai F, Kobiyama K, Ishii KJ, Akira S, Mizuguchi H.

Front Immunol. 2017 Nov 6;8:1456. doi: 10.3389/fimmu.2017.01456. eCollection 2017.

38.

Detection of circulating tumor cells in cervical cancer using a conditionally replicative adenovirus targeting telomerase-positive cells.

Takakura M, Matsumoto T, Nakamura M, Mizumoto Y, Myojyo S, Yamazaki R, Iwadare J, Bono Y, Orisaka S, Obata T, Iizuka T, Kagami K, Nakayama K, Hayakawa H, Sakurai F, Mizuguchi H, Urata Y, Fujiwara T, Kyo S, Sasagawa T, Fujiwara H.

Cancer Sci. 2018 Jan;109(1):231-240. doi: 10.1111/cas.13449. Epub 2017 Dec 9.

39.

Development of therapeutic strategy target for intracellular signaling molecules responsible for the pathogenesis of allergic diseases.

Mizuguchi H.

Nihon Yakurigaku Zasshi. 2017;150(4):188-194. doi: 10.1254/fpj.150.188. Japanese. No abstract available.

PMID:
28966217
40.

Adenovirus vector-mediated macrophage erythroblast attacher (MAEA) overexpression in primary mouse hepatocytes attenuates hepatic gluconeogenesis.

Shimizu K, Okamoto M, Terada T, Sakurai F, Mizuguchi H, Tomita K, Nishinaka T.

Biochem Biophys Rep. 2017 Apr 20;10:192-197. doi: 10.1016/j.bbrep.2017.04.010. eCollection 2017 Jul.

41.

A phase III trial comparing oral S-1/cisplatin and intravenous 5-fluorouracil/cisplatin in patients with untreated diffuse gastric cancer.

Ajani JA, Abramov M, Bondarenko I, Shparyk Y, Gorbunova V, Hontsa A, Otchenash N, Alsina M, Lazarev S, Feliu J, Elme A, Esko V, Abdalla K, Verma U, Benedetti F, Aoyama T, Mizuguchi H, Makris L, Rosati G; DIGEST Study Group.

Ann Oncol. 2017 Sep 1;28(9):2142-2148. doi: 10.1093/annonc/mdx275.

PMID:
28911091
42.

Hepatitis C virus-induced innate immune responses in human iPS cell-derived hepatocyte-like cells.

Sakurai F, Kunito T, Takayama K, Hashimoto R, Tachibana M, Sakamoto N, Wakita T, Mizuguchi H.

Virus Res. 2017 Oct 15;242:7-15. doi: 10.1016/j.virusres.2017.09.004. Epub 2017 Sep 9.

PMID:
28893653
43.

Neonatal Gene Therapy for Hemophilia B by a Novel Adenovirus Vector Showing Reduced Leaky Expression of Viral Genes.

Iizuka S, Sakurai F, Tachibana M, Ohashi K, Mizuguchi H.

Mol Ther Methods Clin Dev. 2017 Jul 8;6:183-193. doi: 10.1016/j.omtm.2017.07.001. eCollection 2017 Sep 15.

44.

Two-Species Migration and Clustering in Two-Dimensional Domains.

Kurowski L, Krause AL, Mizuguchi H, Grindrod P, Van Gorder RA.

Bull Math Biol. 2017 Oct;79(10):2302-2333. doi: 10.1007/s11538-017-0331-0. Epub 2017 Aug 18.

45.

A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2.

Sakai E, Miura Y, Suzuki-Kouyama E, Oka K, Tachibana M, Kawabata K, Sakurai F, Mizuguchi H.

Sci Rep. 2017 Jul 17;7(1):5541. doi: 10.1038/s41598-017-05782-3.

46.

Occludin as a functional marker of vascular endothelial cells on tube-forming activity.

Kanayasu-Toyoda T, Ishii-Watabe A, Kikuchi Y, Kitagawa H, Suzuki H, Tamura H, Tada M, Suzuki T, Mizuguchi H, Yamaguchi T.

J Cell Physiol. 2018 Feb;233(2):1700-1711. doi: 10.1002/jcp.26082. Epub 2017 Aug 17.

PMID:
28681912
47.

Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling.

Mitani S, Takayama K, Nagamoto Y, Imagawa K, Sakurai F, Tachibana M, Sumazaki R, Mizuguchi H.

Mol Ther. 2017 Jun 7;25(6):1420-1433. doi: 10.1016/j.ymthe.2017.04.006. Epub 2017 Apr 24.

48.

Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients.

Togo S, Katagiri N, Namba Y, Tulafu M, Nagahama K, Kadoya K, Takamochi K, Oh S, Suzuki K, Sakurai F, Mizuguchi H, Urata Y, Takahashi K.

Oncotarget. 2017 May 23;8(21):34884-34895. doi: 10.18632/oncotarget.16818.

49.

Cationic liposome-mediated delivery of reovirus enhances the tumor cell-killing efficiencies of reovirus in reovirus-resistant tumor cells.

Sakurai F, Inoue S, Kaminade T, Hotani T, Katayama Y, Hosoyamada E, Terasawa Y, Tachibana M, Mizuguchi H.

Int J Pharm. 2017 May 30;524(1-2):238-247. doi: 10.1016/j.ijpharm.2017.04.006. Epub 2017 Apr 4.

PMID:
28389364
50.

Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection.

Sakurai F, Mitani S, Yamamoto T, Takayama K, Tachibana M, Watashi K, Wakita T, Iijima S, Tanaka Y, Mizuguchi H.

Sci Rep. 2017 Apr 4;7:45698. doi: 10.1038/srep45698.

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