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Items: 1 to 50 of 57

1.

A Facile Asymmetric Synthesis of 1,2,3-Substituted Indenes.

Romines KR, Lovasz KD, Mizsak SA, Morris JK, Seest EP, Han F, Tulinsky J, Judge TM, Gammill RB.

J Org Chem. 1999 Mar 5;64(5):1733-1737. No abstract available.

PMID:
11674247
2.

Novel Asymmetric Synthesis of Atropisomeric 6-Aryl Pyrazinones via an Unusual Chirality Transfer Process.

Tulinsky J, Cheney BV, Mizsak SA, Watt W, Han F, Dolak LA, Judge T, Gammill RB.

J Org Chem. 1999 Jan 8;64(1):93-100.

PMID:
11674090
3.

Chemical Oxidation of 2,4-Diamino-pyrrolo[2,3-d]pyrimidines.

Bundy GL, Gremban RS, Banitt LS, Palmer JR, Mizsak SA, Han F.

J Org Chem. 1998 Oct 16;63(21):7542-7546. No abstract available.

PMID:
11672414
4.

Syntheses of 1,2-diamino and 1,2-aminoalcohol derivatives in the piperidine and pyrrolidine series as anti-amnesic agents.

Zhao S, Freeman JP, Bacon CL, Fox GB, O'Driscoll E, Foley AG, Kelly J, Farrell U, Regan C, Mizsak SA, Szmuszkovicz J.

Bioorg Med Chem. 1999 Aug;7(8):1647-54.

PMID:
10482457
5.

Syntheses of benzoquinolizidine and benzoindolizidine derivatives as anti-amnesic agents.

Zhao S, Totleben MJ, Freeman JP, Bacon CL, Fox GB, O'Driscoll E, Foley AG, Kelly J, Farrell U, Regan C, Mizsak SA, Szmuszkovicz J.

Bioorg Med Chem. 1999 Aug;7(8):1637-46.

PMID:
10482456
6.

Isolation and identification of a major metabolite of PNU-107859, an MMP inhibitor from the biliary fluid of rats.

Kuo MS, Yurek DA, Mizsak SA, Prairie MD, Mattern SJ, DeKoning TF.

J Pharm Sci. 1999 Jul;88(7):705-8.

PMID:
10393568
7.

Solution structures of stromelysin complexed to thiadiazole inhibitors.

Stockman BJ, Waldon DJ, Gates JA, Scahill TA, Kloosterman DA, Mizsak SA, Jacobsen EJ, Belonga KL, Mitchell MA, Mao B, Petke JD, Goodman L, Powers EA, Ledbetter SR, Kaytes PS, Vogeli G, Marshall VP, Petzold GL, Poorman RA.

Protein Sci. 1998 Nov;7(11):2281-6.

8.

In vitro metabolic transformations of 2,4-dipyrrolidinylpyrimidine: a chemical probe for P450-mediated oxidation of tirilazad mesylate.

Streeper RT, Pearson PG, Zhao Z, Mizsak SA, Sanders PE, Wienkers LC, Vrbanac JJ.

Xenobiotica. 1997 Nov;27(11):1131-45.

PMID:
9413917
9.

Microbiological Oxygenation of 1-Azidoadamantane and of N-Benzoyl-3-noradamantanamine.

Davis CR, Johnson RA, Cialdella JI, Liggett WF, Mizsak SA, Han F, Marshall VP.

J Org Chem. 1997 Apr 4;62(7):2252-2254. No abstract available.

PMID:
11671536
10.

Microbiological Oxygenation of Bridgehead Azabicycloalkanes.

Davis CR, Johnson RA, Cialdella JI, Liggett WF, Mizsak SA, Marshall VP.

J Org Chem. 1997 Apr 4;62(7):2244-2251.

PMID:
11671535
11.

Synthesis of an Azasteroid Using an Acyl Iminium Ion-Initiated Tandem Cyclization.

Romero AG, Leiby JA, Mizsak SA.

J Org Chem. 1996 Oct 4;61(20):6974-6979.

PMID:
11667595
12.

Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships.

Romines KR, Morris JK, Howe WJ, Tomich PK, Horng MM, Chong KT, Hinshaw RR, Anderson DJ, Strohbach JW, Turner SR, Mizsak SA.

J Med Chem. 1996 Sep 27;39(20):4125-30.

PMID:
8831779
13.

Cyclopentene Synthesis from 1,3-Dienes via Base-Induced Ring Contraction of 3,6-Dihydro-2H-thiopyrans: Studies on Diastereoselection and Mechanism.

Larsen SD, Fisher PV, Libby BE, Jensen RM, Mizsak SA, Watt W, Ronk WR, Hill ST.

J Org Chem. 1996 Jul 12;61(14):4725-4738.

PMID:
11667404
14.

Synthesis of novel 2,4-diaminopyrrolo-[2,3-d]pyrimidines with antioxidant, neuroprotective, and antiasthma activity.

Bundy GL, Ayer DE, Banitt LS, Belonga KL, Mizsak SA, Palmer JR, Tustin JM, Chin JE, Hall ED, Linseman KL, et al.

J Med Chem. 1995 Oct 13;38(21):4161-3. No abstract available.

PMID:
7473542
15.

Production, isolation, and identification of dihydroepiepoformin as an IL-1 receptor antagonistic component in Penicillium patulum.

Kuo MS, Yurek DA, Mizsak SA, Marshall VP, Liggett WF, Cialdella JI, Laborde AL, Shelly JA, Truesdell SE.

J Antibiot (Tokyo). 1995 Aug;48(8):888-90. No abstract available.

16.

In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase.

Wienkers LC, Steenwyk RC, Mizsak SA, Pearson PG.

Drug Metab Dispos. 1995 Mar;23(3):383-92.

PMID:
7628305
17.

Synthesis and biological activity of spirocyclic benzopyran imidazolone potassium channel openers.

Gadwood RC, Kamdar BV, Dubray LA, Wolfe ML, Smith MP, Watt W, Mizsak SA, Groppi VE.

J Med Chem. 1993 May 14;36(10):1480-7.

PMID:
8496916
18.

Naphtho and benzo analogues of the kappa opioid agonist trans-(+/-)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide.

Freeman JP, Michalson ET, D'Andrea SV, Baczynskyj L, Von Voigtlander PF, Lahti RA, Smith MW, Lawson CF, Scahill TA, Mizsak SA, et al.

J Med Chem. 1991 Jun;34(6):1891-6.

PMID:
1648141
19.

Structure elucidation of ficellomycin.

Kuo MS, Yurek DA, Mizsak SA.

J Antibiot (Tokyo). 1989 Mar;42(3):357-60.

20.

O-demethylpaulomycins A and B, U-77,802 and U-77,803, paulomenols A and B, new metabolites produced by Streptomyces paulus.

Argoudelis AD, Baczynskyj L, Mizsak SA, Shilliday FB.

J Antibiot (Tokyo). 1988 Oct;41(10):1316-30.

21.

Adenylylation of trospectomycin by crude enzyme preparations from Escherichia coli.

Yagi Y, Baczynskyj L, Mizsak SA, Argoudelis AD.

J Antibiot (Tokyo). 1988 Oct;41(10):1452-61.

22.

Structural relationships between senfolomycins and paulomycins.

Argoudelis AD, Baczynskyj L, Mizsak SA, Shilliday FB, Wiley PF.

J Antibiot (Tokyo). 1988 Sep;41(9):1212-22.

23.

New paulomycins produced by Streptomyces paulus.

Argoudelis AD, Baczynskyj L, Haak WJ, Knoll WM, Mizsak SA, Shilliday FB.

J Antibiot (Tokyo). 1988 Feb;41(2):157-69.

24.

Paulomycin-related antibiotics: paldimycins and antibiotics 273a2. Isolation and characterization.

Argoudelis AD, Baczynskyj L, Buege JA, Marshall VP, Mizsak SA, Wiley PF.

J Antibiot (Tokyo). 1987 Apr;40(4):408-18.

25.

Paldimycins A and B and antibiotics 273a2 alpha and 273a2 beta. Synthesis and characterization.

Argoudelis AD, Baczynskyj L, Mizsak SA, Shilliday FB, Spinelli PA, DeZwaan J.

J Antibiot (Tokyo). 1987 Apr;40(4):419-36.

26.

Isolation, identification and synthesis of a metabolite of tazadolene succinate.

Darlington WH, Constable DA, Baczynskyj L, Mizsak SA, Scahill TA, Dring LG, McCall JM, Szmuszkovicz J.

Drug Des Deliv. 1987 Feb;1(3):225-30.

PMID:
3509335
27.

Acivicin (AT 125, U 42126): isolation and structure of an alkali-induced contaminant.

Martin DG, Mizsak SA, Nielsen JW.

J Antibiot (Tokyo). 1986 Apr;39(4):603-5. No abstract available.

28.

Discovery of an arachidonic acid C-8 lipoxygenase in the gorgonian coral Pseudoplexaura porosa.

Bundy GL, Nidy EG, Epps DE, Mizsak SA, Wnuk RJ.

J Biol Chem. 1986 Jan 15;261(2):747-51.

29.

CC-1065 transformations.

Martin DG, Mizsak SA, Krueger WC.

J Antibiot (Tokyo). 1985 Jun;38(6):746-52.

30.

The structure of paulomycin.

Wiley PF, Mizsak SA, Baczynskyj L, Argoudelis AD.

J Antibiot (Tokyo). 1984 Oct;37(10):1273-5. No abstract available.

31.

Desertomycin: purification and physical-chemical properties.

Dolak LA, Reusser F, Baczynskyj L, Mizsak SA, Hannon BR, Castle TM.

J Antibiot (Tokyo). 1983 Jan;36(1):13-9.

32.

Isolation and characterization of a new antibiotic U-62162.

Slechta L, Cialdella JI, Mizsak SA, Hoeksema H.

J Antibiot (Tokyo). 1982 May;35(5):556-60.

33.

Paulomycins A and B. Isolation and characterization.

Argoudelis AD, Brinkley TA, Brodasky TF, Buege JA, Meyer HF, Mizsak SA.

J Antibiot (Tokyo). 1982 Mar;35(3):285-94.

34.

9-O-Esters of nodusmicin.

Magerlein BJ, Mizsak SA.

J Antibiot (Tokyo). 1982 Jan;35(1):111-2. No abstract available.

35.

Chemical modification of aminoglycosides. 3. Synthesis of 2"-deoxykanamycins from neamine.

Reid RJ, Mizsak SA, Reineke LM, Zurenko GE, Stern KF, Magerlein BJ.

J Med Chem. 1981 Dec;24(12):1487-92.

PMID:
7310825
36.

CC-1065 (NSC 298223), a potent new antitumor agent improved production and isolation, characterization and antitumor activity.

Martin DG, Biles C, Gerpheide SA, Hanka LJ, Krueger WC, McGovren JP, Mizsak SA, Neil GL, Stewart JC, Visser J.

J Antibiot (Tokyo). 1981 Sep;34(9):1119-25. No abstract available.

37.

Derivatization and purification of acivicin (AT-125, U-42,126).

Martin DG, Biles C, Mizsak SA.

J Antibiot (Tokyo). 1981 Apr;34(4):459-61. No abstract available.

38.

Structure of CC-1065 (NSC-298223), a new antitumor antibiotic.

Martin DG, Chidester CG, Duchamp DJ, Mizsak SA.

J Antibiot (Tokyo). 1980 Aug;33(8):902-3. No abstract available.

39.

The chemistry of rubradirin. III. The rubradiric acids and the structure of rubradirin.

Hoeksema H, Mizsak SA, Baczynskyj L.

J Antibiot (Tokyo). 1979 Jul;32(7):773-6. No abstract available.

40.

The chemistry of rubradirin. II. Rubranitrose.

Mizsak SA, Hoeksema H, Pschigoda LM.

J Antibiot (Tokyo). 1979 Jul;32(7):771-2. No abstract available.

41.

The isolation and characterization of rubradirin B.

Hoeksema H, Lewis C, Mizsak SA, Shiley JA, Wait DR, Whaley HA, Zurenko GE.

J Antibiot (Tokyo). 1978 Oct;31(10):945-8.

42.

The chemistry of the rubradirins. I. The structures of rubransarols A and B.

Hoeksema H, Chidester C, Mizsak SA, Baczynskyj L.

J Antibiot (Tokyo). 1978 Oct;31(10):1067-9.

43.

Microbial transformation of antibiotics. Clindamycin ribonucleotides.

Argoudelis AD, Coats JH, Mizsak SA.

J Antibiot (Tokyo). 1977 Jun;30(6):474-87.

44.

Melinacidins II, III and IV. Structural studies.

Argoudelis AD, Mizsak SA.

J Antibiot (Tokyo). 1977 Jun;30(6):468-73.

45.

Structure of nogalamycin.

Wiley PF, Kelly RB, Caron EL, Wiley VH, Johnson JH, MacKellar FA, Mizsak SA.

J Am Chem Soc. 1977 Jan 19;99(2):542-9. No abstract available.

PMID:
830691
46.

The structure of feldamycin.

Argoudelis AD, Mizsak SA, Baczynskyj L, Wnuk RJ.

J Antibiot (Tokyo). 1976 Oct;29(10):1117-9. No abstract available.

47.

Antibiotics produced by Streptomyces ficellus II. Feldamycin and nojirimycin.

Argoudelis AD, Reusser F, Mizsak SA, Baczynskyj L.

J Antibiot (Tokyo). 1976 Oct;29(10):1007-14.

48.

Antibiotics produced by Streptomyces ficellus. I. Ficellomycin.

Argoudelis AD, Reusser F, Whaley HA, Baczynskyj L, Mizsak SA, Wnuk RJ.

J Antibiot (Tokyo). 1976 Oct;29(10):1001-6.

49.

1-methylpseudouridine, a metabolite of Streptomyces platensis.

Argoudelis AD, Mizsak SA.

J Antibiot (Tokyo). 1976 Aug;29(8):818-23.

50.

Rancinamycins I, II, III and IV structural studies.

Argoudelis AD, Sprague RW, Mizsak SA.

J Antibiot (Tokyo). 1976 Aug;29(8):787-96.

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