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Items: 1 to 50 of 85

1.

NF-κB RelA is required for hepatoprotection during pneumonia and sepsis.

Kim Y, Allen E, Baird LA, Symer EM, Korkmaz FT, Na E, Odom CV, Jones MR, Mizgerd JP, Traber KE, Quinton LJ.

Infect Immun. 2019 Jun 3. pii: IAI.00132-19. doi: 10.1128/IAI.00132-19. [Epub ahead of print]

PMID:
31160364
2.

Inflammation and Pneumonia: Why Are Some More Susceptible than Others?

Mizgerd JP.

Clin Chest Med. 2018 Dec;39(4):669-676. doi: 10.1016/j.ccm.2018.07.002. Review.

PMID:
30390740
3.

Integrative Physiology of Pneumonia.

Quinton LJ, Walkey AJ, Mizgerd JP.

Physiol Rev. 2018 Jul 1;98(3):1417-1464. doi: 10.1152/physrev.00032.2017. Review.

4.

Future Research Directions in Pneumonia. NHLBI Working Group Report.

Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, Orihuela CJ, Peyrani P, Prince AS, Ramírez JA, Ridge KM, Sethi S, Suratt BT, Sznajder JI, Tsalik EL, Walkey AJ, Yende S, Aggarwal NR, Caler EV, Mizgerd JP.

Am J Respir Crit Care Med. 2018 Jul 15;198(2):256-263. doi: 10.1164/rccm.201801-0139WS.

5.

Riboflavin Metabolism Variation among Clinical Isolates of Streptococcus pneumoniae Results in Differential Activation of Mucosal-associated Invariant T Cells.

Hartmann N, McMurtrey C, Sorensen ML, Huber ME, Kurapova R, Coleman FT, Mizgerd JP, Hildebrand W, Kronenberg M, Lewinsohn DM, Harriff MJ.

Am J Respir Cell Mol Biol. 2018 Jun;58(6):767-776. doi: 10.1165/rcmb.2017-0290OC.

6.

Timing of valproic acid in acute lung injury: prevention is the best therapy?

Kasotakis G, Galvan MD, Osathanugrah P, Dharia N, Bufe L, Breed Z, Mizgerd JP, Remick DG.

J Surg Res. 2017 Dec;220:206-212. doi: 10.1016/j.jss.2017.06.088. Epub 2017 Jul 31.

7.

MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage.

Willinger CM, Rong J, Tanriverdi K, Courchesne PL, Huan T, Wasserman GA, Lin H, Dupuis J, Joehanes R, Jones MR, Chen G, Benjamin EJ, O'Connor GT, Mizgerd JP, Freedman JE, Larson MG, Levy D.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001678. doi: 10.1161/CIRCGENETICS.116.001678.

8.

Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.

Wasserman GA, Szymaniak AD, Hinds AC, Yamamoto K, Kamata H, Smith NM, Hilliard KL, Carrieri C, Labadorf AT, Quinton LJ, Ai X, Varelas X, Chen F, Mizgerd JP, Fine A, O'Carroll D, Jones MR.

J Clin Invest. 2017 Oct 2;127(10):3866-3876. doi: 10.1172/JCI94639. Epub 2017 Sep 18.

9.

The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.

Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez NP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ, Mizgerd JP, Jones MR.

PLoS One. 2017 Jun 30;12(6):e0179797. doi: 10.1371/journal.pone.0179797. eCollection 2017.

10.

Myeloid-epithelial cross talk coordinates synthesis of the tissue-protective cytokine leukemia inhibitory factor during pneumonia.

Traber KE, Symer EM, Allen E, Kim Y, Hilliard KL, Wasserman GA, Stewart CL, Jones MR, Mizgerd JP, Quinton LJ.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L548-L558. doi: 10.1152/ajplung.00482.2016. Epub 2017 May 18.

11.

Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia.

Smith NM, Wasserman GA, Coleman FT, Hilliard KL, Yamamoto K, Lipsitz E, Malley R, Dooms H, Jones MR, Quinton LJ, Mizgerd JP.

Mucosal Immunol. 2018 Jan;11(1):220-235. doi: 10.1038/mi.2017.43. Epub 2017 May 17.

12.

Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity.

Coleman FT, Blahna MT, Kamata H, Yamamoto K, Zabinski MC, Kramnik I, Wilson AA, Kotton DN, Quinton LJ, Jones MR, Pelton SI, Mizgerd JP.

J Infect Dis. 2017 Aug 15;216(4):425-435. doi: 10.1093/infdis/jix159.

13.

3' Uridylation controls mature microRNA turnover during CD4 T-cell activation.

Gutiérrez-Vázquez C, Enright AJ, Rodríguez-Galán A, Pérez-García A, Collier P, Jones MR, Benes V, Mizgerd JP, Mittelbrunn M, Ramiro AR, Sánchez-Madrid F.

RNA. 2017 Jun;23(6):882-891. doi: 10.1261/rna.060095.116. Epub 2017 Mar 28.

14.

Pathogenesis of severe pneumonia: advances and knowledge gaps.

Mizgerd JP.

Curr Opin Pulm Med. 2017 May;23(3):193-197. doi: 10.1097/MCP.0000000000000365. Review.

15.

Valproic acid mitigates the inflammatory response and prevents acute respiratory distress syndrome in a murine model of Escherichia coli pneumonia at the expense of bacterial clearance.

Kasotakis G, Galvan M, King E, Sarkar B, Stucchi A, Mizgerd JP, Burke PA, Remick D.

J Trauma Acute Care Surg. 2017 Apr;82(4):758-765. doi: 10.1097/TA.0000000000001389.

16.

Role for the Aryl Hydrocarbon Receptor and Diverse Ligands in Oral Squamous Cell Carcinoma Migration and Tumorigenesis.

Stanford EA, Ramirez-Cardenas A, Wang Z, Novikov O, Alamoud K, Koutrakis P, Mizgerd JP, Genco CA, Kukuruzinska M, Monti S, Bais MV, Sherr DH.

Mol Cancer Res. 2016 Aug;14(8):696-706. doi: 10.1158/1541-7786.MCR-16-0069. Epub 2016 Apr 29.

17.

Epithelial Cell-Derived Secreted and Transmembrane 1a Signals to Activated Neutrophils during Pneumococcal Pneumonia.

Kamata H, Yamamoto K, Wasserman GA, Zabinski MC, Yuen CK, Lung WY, Gower AC, Belkina AC, Ramirez MI, Deng JC, Quinton LJ, Jones MR, Mizgerd JP.

Am J Respir Cell Mol Biol. 2016 Sep;55(3):407-18. doi: 10.1165/rcmb.2015-0261OC.

18.

Community-Acquired Pneumonia Requiring Hospitalization.

Mizgerd JP.

N Engl J Med. 2015 Dec 10;373(24):2380. doi: 10.1056/NEJMc1511751. No abstract available.

PMID:
26650160
19.

Activation of Hepatic STAT3 Maintains Pulmonary Defense during Endotoxemia.

Hilliard KL, Allen E, Traber KE, Kim Y, Wasserman GA, Jones MR, Mizgerd JP, Quinton LJ.

Infect Immun. 2015 Oct;83(10):4015-27. doi: 10.1128/IAI.00464-15. Epub 2015 Jul 27.

20.

Induction of STAT3-Dependent CXCL5 Expression and Neutrophil Recruitment by Oncostatin-M during Pneumonia.

Traber KE, Hilliard KL, Allen E, Wasserman GA, Yamamoto K, Jones MR, Mizgerd JP, Quinton LJ.

Am J Respir Cell Mol Biol. 2015 Oct;53(4):479-88. doi: 10.1165/rcmb.2014-0342OC.

21.

The Lung-Liver Axis: A Requirement for Maximal Innate Immunity and Hepatoprotection during Pneumonia.

Hilliard KL, Allen E, Traber KE, Yamamoto K, Stauffer NM, Wasserman GA, Jones MR, Mizgerd JP, Quinton LJ.

Am J Respir Cell Mol Biol. 2015 Sep;53(3):378-90. doi: 10.1165/rcmb.2014-0195OC.

22.

The infant nose. Introducing the respiratory tract to the world.

Mizgerd JP.

Am J Respir Crit Care Med. 2014 Dec 1;190(11):1206-7. doi: 10.1164/rccm.201410-1919ED. No abstract available.

23.

Myeloid ZFP36L1 does not regulate inflammation or host defense in mouse models of acute bacterial infection.

Hyatt LD, Wasserman GA, Rah YJ, Matsuura KY, Coleman FT, Hilliard KL, Pepper-Cunningham ZA, Ieong M, Stumpo DJ, Blackshear PJ, Quinton LJ, Mizgerd JP, Jones MR.

PLoS One. 2014 Oct 9;9(10):e109072. doi: 10.1371/journal.pone.0109072. eCollection 2014.

24.

Dynamics of lung defense in pneumonia: resistance, resilience, and remodeling.

Quinton LJ, Mizgerd JP.

Annu Rev Physiol. 2015;77:407-30. doi: 10.1146/annurev-physiol-021014-071937. Epub 2014 Aug 13. Review.

25.

The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury.

Ubags ND, Vernooy JH, Burg E, Hayes C, Bement J, Dilli E, Zabeau L, Abraham E, Poch KR, Nick JA, Dienz O, Zuñiga J, Wargo MJ, Mizgerd JP, Tavernier J, Rincón M, Poynter ME, Wouters EF, Suratt BT.

Crit Care Med. 2014 Feb;42(2):e143-51. doi: 10.1097/CCM.0000000000000048.

26.

Roles of lung epithelium in neutrophil recruitment during pneumococcal pneumonia.

Yamamoto K, Ahyi AN, Pepper-Cunningham ZA, Ferrari JD, Wilson AA, Jones MR, Quinton LJ, Mizgerd JP.

Am J Respir Cell Mol Biol. 2014 Feb;50(2):253-62. doi: 10.1165/rcmb.2013-0114OC.

27.

Roles of STAT3 in protein secretion pathways during the acute-phase response.

Ahyi AN, Quinton LJ, Jones MR, Ferrari JD, Pepper-Cunningham ZA, Mella JR, Remick DG, Mizgerd JP.

Infect Immun. 2013 May;81(5):1644-53. doi: 10.1128/IAI.01332-12. Epub 2013 Mar 4.

28.

IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality.

Zhang H, Neuhöfer P, Song L, Rabe B, Lesina M, Kurkowski MU, Treiber M, Wartmann T, Regnér S, Thorlacius H, Saur D, Weirich G, Yoshimura A, Halangk W, Mizgerd JP, Schmid RM, Rose-John S, Algül H.

J Clin Invest. 2013 Mar;123(3):1019-31. doi: 10.1172/JCI64931. Epub 2013 Feb 15.

29.

Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages.

Wilson AA, Kwok LW, Porter EL, Payne JG, McElroy GS, Ohle SJ, Greenhill SR, Blahna MT, Yamamoto K, Jean JC, Mizgerd JP, Kotton DN.

Mol Ther. 2013 Apr;21(4):825-33. doi: 10.1038/mt.2013.19. Epub 2013 Feb 12.

30.

Direct control of hepatic glucose production by interleukin-13 in mice.

Stanya KJ, Jacobi D, Liu S, Bhargava P, Dai L, Gangl MR, Inouye K, Barlow JL, Ji Y, Mizgerd JP, Qi L, Shi H, McKenzie AN, Lee CH.

J Clin Invest. 2013 Jan;123(1):261-71. doi: 10.1172/JCI64941. Epub 2012 Dec 21.

31.

Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival.

Jones MR, Blahna MT, Kozlowski E, Matsuura KY, Ferrari JD, Morris SA, Powers JT, Daley GQ, Quinton LJ, Mizgerd JP.

PLoS Genet. 2012;8(11):e1003105. doi: 10.1371/journal.pgen.1003105. Epub 2012 Nov 29.

32.

Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus.

Bartlett NW, Slater L, Glanville N, Haas JJ, Caramori G, Casolari P, Clarke DL, Message SD, Aniscenko J, Kebadze T, Zhu J, Mallia P, Mizgerd JP, Belvisi M, Papi A, Kotenko SV, Johnston SL, Edwards MR.

EMBO Mol Med. 2012 Dec;4(12):1244-60. doi: 10.1002/emmm.201201650. Epub 2012 Nov 14.

33.

Type I alveolar epithelial cells mount innate immune responses during pneumococcal pneumonia.

Yamamoto K, Ferrari JD, Cao Y, Ramirez MI, Jones MR, Quinton LJ, Mizgerd JP.

J Immunol. 2012 Sep 1;189(5):2450-9. doi: 10.4049/jimmunol.1200634. Epub 2012 Jul 27.

34.

Respiratory infection and the impact of pulmonary immunity on lung health and disease.

Mizgerd JP.

Am J Respir Crit Care Med. 2012 Nov 1;186(9):824-9. doi: 10.1164/rccm.201206-1063PP. Epub 2012 Jul 12.

35.

Leukemia inhibitory factor signaling is required for lung protection during pneumonia.

Quinton LJ, Mizgerd JP, Hilliard KL, Jones MR, Kwon CY, Allen E.

J Immunol. 2012 Jun 15;188(12):6300-8. doi: 10.4049/jimmunol.1200256. Epub 2012 May 11.

36.

Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice.

Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Hilliard KL, Zhang X, Sabharwal V, Algül H, Akira S, Schmid RM, Pelton SI, Spira A, Mizgerd JP.

J Clin Invest. 2012 May;122(5):1758-63. doi: 10.1172/JCI59408. Epub 2012 Apr 2.

37.

Terminal uridyltransferase enzyme Zcchc11 promotes cell proliferation independent of its uridyltransferase activity.

Blahna MT, Jones MR, Quinton LJ, Matsuura KY, Mizgerd JP.

J Biol Chem. 2011 Dec 9;286(49):42381-9. doi: 10.1074/jbc.M111.259689. Epub 2011 Oct 17.

38.

Earliest innate immune responses require macrophage RelA during pneumococcal pneumonia.

Pittet LA, Quinton LJ, Yamamoto K, Robson BE, Ferrari JD, Algül H, Schmid RM, Mizgerd JP.

Am J Respir Cell Mol Biol. 2011 Sep;45(3):573-81. doi: 10.1165/rcmb.2010-0210OC. Epub 2011 Jan 7.

39.

NF-κB and STAT3 signaling hubs for lung innate immunity.

Quinton LJ, Mizgerd JP.

Cell Tissue Res. 2011 Jan;343(1):153-65. doi: 10.1007/s00441-010-1044-y. Epub 2010 Sep 25. Review.

PMID:
20872151
40.

Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus.

Perrone LA, Szretter KJ, Katz JM, Mizgerd JP, Tumpey TM.

J Infect Dis. 2010 Oct 15;202(8):1161-70. doi: 10.1086/656365.

41.

Zcchc11-dependent uridylation of microRNA directs cytokine expression.

Jones MR, Quinton LJ, Blahna MT, Neilson JR, Fu S, Ivanov AR, Wolf DA, Mizgerd JP.

Nat Cell Biol. 2009 Sep;11(9):1157-63. doi: 10.1038/ncb1931. Epub 2009 Aug 23.

42.

Mechanisms of the hepatic acute-phase response during bacterial pneumonia.

Quinton LJ, Jones MR, Robson BE, Mizgerd JP.

Infect Immun. 2009 Jun;77(6):2417-26. doi: 10.1128/IAI.01300-08. Epub 2009 Mar 16.

43.

Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia.

Li Y, Jia Y, Pichavant M, Loison F, Sarraj B, Kasorn A, You J, Robson BE, Umetsu DT, Mizgerd JP, Ye K, Luo HR.

Blood. 2009 May 14;113(20):4930-41. doi: 10.1182/blood-2008-06-161414. Epub 2009 Mar 13.

44.

Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation.

Huang Y, Zhang J, McHenry KT, Kim MM, Zeng W, Lopez-Pajares V, Dibble CC, Mizgerd JP, Yuan ZM.

Cancer Res. 2008 Nov 15;68(22):9131-6. doi: 10.1158/0008-5472.CAN-08-3025.

45.

The systemic and pulmonary LPS binding protein response to intratracheal lipopolysaccharide.

Gamble L, Bagby GJ, Quinton LJ, Happel KI, Mizgerd JP, Zhang P, Nelson S.

Shock. 2009 Feb;31(2):212-7. doi: 10.1097/SHK.0b013e31817c0d7d.

PMID:
18520704
46.

Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6.

Lang JE, Williams ES, Mizgerd JP, Shore SA.

Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L1013-20. doi: 10.1152/ajplung.00122.2007. Epub 2008 Mar 21.

47.

Acute lower respiratory tract infection.

Mizgerd JP.

N Engl J Med. 2008 Feb 14;358(7):716-27. doi: 10.1056/NEJMra074111. Review. No abstract available.

48.

Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia.

Quinton LJ, Jones MR, Robson BE, Simms BT, Whitsett JA, Mizgerd JP.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):699-706. doi: 10.1165/rcmb.2007-0365OC. Epub 2008 Jan 10.

49.

Animal models of human pneumonia.

Mizgerd JP, Skerrett SJ.

Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L387-98. Epub 2007 Dec 27. Review.

50.

Type I interleukin-1 receptor is required for pulmonary responses to subacute ozone exposure in mice.

Johnston RA, Mizgerd JP, Flynt L, Quinton LJ, Williams ES, Shore SA.

Am J Respir Cell Mol Biol. 2007 Oct;37(4):477-84. Epub 2007 Jun 15.

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