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Items: 1 to 50 of 94

1.

Correction: Alternative mammalian target of rapamycin (mTOR) signal activation in sorafenib-resistant hepatocellular carcinoma cells revealed by array-based pathway profiling.

Masuda M, Chen WY, Miyanaga A, Nakamura Y, Kawasaki K, Sakuma T, Ono M, Chen CL, Honda K, Yamada T.

Mol Cell Proteomics. 2020 Jan;19(1):223. doi: 10.1074/mcp.AAC119.001903. No abstract available.

2.

Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis.

Kudo F, Tsunoda T, Yamaguchi K, Miyanaga A, Eguchi T.

Biochemistry. 2019 Dec 24;58(51):5112-5116. doi: 10.1021/acs.biochem.9b00981. Epub 2019 Dec 13.

PMID:
31825604
3.

Functional and Structural Analyses of the Split-Dehydratase Domain in the Biosynthesis of Macrolactam Polyketide Cremimycin.

Kawasaki D, Miyanaga A, Chisuga T, Kudo F, Eguchi T.

Biochemistry. 2019 Dec 3;58(48):4799-4803. doi: 10.1021/acs.biochem.9b00897. Epub 2019 Nov 18.

PMID:
31721563
4.

Structural Analysis of the Glycine Oxidase Homologue CmiS2 Reveals a Unique Substrate Recognition Mechanism for Formation of a β-Amino Acid Starter Unit in Cremimycin Biosynthesis.

Kawasaki D, Chisuga T, Miyanaga A, Kudo F, Eguchi T.

Biochemistry. 2019 Jun 18;58(24):2706-2709. doi: 10.1021/acs.biochem.9b00444. Epub 2019 Jun 4.

PMID:
31154757
5.

Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren's Syndrome.

Shima N, Murosaki T, Yamamoto S, Miyanaga A, Kusaka H, Nagatani K, Nagashima T, Sawada M, Iwamoto M, Minota S.

Case Rep Rheumatol. 2019 Apr 11;2019:4156781. doi: 10.1155/2019/4156781. eCollection 2019.

6.

Phase II trial of S-1 plus cisplatin combined with bevacizumab for advanced non-squamous non-small cell lung cancer (TCOG LC-1202).

Miyanaga A, Kubota K, Hosomi Y, Okuma Y, Minato K, Fujimoto S, Okamoto H, Satouchi M, Isobe H, Aono H, Takiguchi Y, Gemma A; Tokyo Cooperative Oncology Group.

Jpn J Clin Oncol. 2019 Aug 1;49(8):749-754. doi: 10.1093/jjco/hyz064.

PMID:
31070750
7.

Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis.

Cieślak J, Miyanaga A, Takaishi M, Kudo F, Eguchi T.

Acta Crystallogr F Struct Biol Commun. 2019 Apr 1;75(Pt 4):299-306. doi: 10.1107/S2053230X19002863. Epub 2019 Apr 2.

PMID:
30950831
8.

An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket.

Ishikawa F, Miyanaga A, Kitayama H, Nakamura S, Nakanishi I, Kudo F, Eguchi T, Tanabe G.

Angew Chem Int Ed Engl. 2019 May 20;58(21):6906-6910. doi: 10.1002/anie.201900318. Epub 2019 Apr 23.

PMID:
30945421
9.

Identification, characterization, and structural analyses of a fungal endo-β-1,2-glucanase reveal a new glycoside hydrolase family.

Tanaka N, Nakajima M, Narukawa-Nara M, Matsunaga H, Kamisuki S, Aramasa H, Takahashi Y, Sugimoto N, Abe K, Terada T, Miyanaga A, Yamashita T, Sugawara F, Kamakura T, Komba S, Nakai H, Taguchi H.

J Biol Chem. 2019 May 10;294(19):7942-7965. doi: 10.1074/jbc.RA118.007087. Epub 2019 Mar 29.

PMID:
30926603
10.

Interstitial lung disease associated with nanoparticle albumin-bound paclitaxel treatment in patients with lung cancer.

Kashiwada T, Saito Y, Terasaki Y, Hisakane K, Takeuchi S, Sugano T, Miyanaga A, Noro R, Minegishi Y, Seike M, Kubota K, Gemma A.

Jpn J Clin Oncol. 2019 Feb 1;49(2):165-173. doi: 10.1093/jjco/hyy180.

PMID:
30508192
11.
12.

Michael additions in polyketide biosynthesis.

Miyanaga A.

Nat Prod Rep. 2019 Mar 20;36(3):531-547. doi: 10.1039/c8np00071a. Review.

PMID:
30311933
13.

Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products.

Kudo F, Miyanaga A, Eguchi T.

J Ind Microbiol Biotechnol. 2019 Mar;46(3-4):515-536. doi: 10.1007/s10295-018-2084-7. Epub 2018 Oct 5. Review.

PMID:
30291534
14.

Hybrid System of an Optical Nanofibre and a Single Quantum Dot Operated at Cryogenic Temperatures.

Shafi KM, Luo W, Yalla R, Iida K, Tsutsumi E, Miyanaga A, Hakuta K.

Sci Rep. 2018 Sep 10;8(1):13494. doi: 10.1038/s41598-018-31888-3.

15.

Structural Basis of Sequential Allosteric Transitions in Tetrameric d-Lactate Dehydrogenases from Three Gram-Negative Bacteria.

Furukawa N, Miyanaga A, Nakajima M, Taguchi H.

Biochemistry. 2018 Sep 18;57(37):5388-5406. doi: 10.1021/acs.biochem.8b00557. Epub 2018 Sep 7.

PMID:
30149697
16.

Protein-protein interactions in polyketide synthase-nonribosomal peptide synthetase hybrid assembly lines.

Miyanaga A, Kudo F, Eguchi T.

Nat Prod Rep. 2018 Nov 14;35(11):1185-1209. doi: 10.1039/c8np00022k. Review.

PMID:
30074030
17.

Biochemical and Structural Analysis of FomD That Catalyzes the Hydrolysis of Cytidylyl ( S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis.

Sato S, Miyanaga A, Kim SY, Kuzuyama T, Kudo F, Eguchi T.

Biochemistry. 2018 Aug 14;57(32):4858-4866. doi: 10.1021/acs.biochem.8b00690. Epub 2018 Jul 25.

PMID:
30010320
18.

Overcoming drug-tolerant cancer cell subpopulations showing AXL activation and epithelial-mesenchymal transition is critical in conquering ALK-positive lung cancer.

Nakamichi S, Seike M, Miyanaga A, Chiba M, Zou F, Takahashi A, Ishikawa A, Kunugi S, Noro R, Kubota K, Gemma A.

Oncotarget. 2018 Jun 5;9(43):27242-27255. doi: 10.18632/oncotarget.25531. eCollection 2018 Jun 5.

19.

Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis.

Miyanaga A, Ouchi R, Ishikawa F, Goto E, Tanabe G, Kudo F, Eguchi T.

J Am Chem Soc. 2018 Jun 27;140(25):7970-7978. doi: 10.1021/jacs.8b04162. Epub 2018 Jun 13.

PMID:
29870659
20.

Characterization and Structural Analysis of a Novel exo-Type Enzyme Acting on β-1,2-Glucooligosaccharides from Parabacteroides distasonis.

Shimizu H, Nakajima M, Miyanaga A, Takahashi Y, Tanaka N, Kobayashi K, Sugimoto N, Nakai H, Taguchi H.

Biochemistry. 2018 Jul 3;57(26):3849-3860. doi: 10.1021/acs.biochem.8b00385. Epub 2018 May 25.

PMID:
29763309
21.

Oral rehydration solution (OS-1) as a substitute of intravenous hydration after cisplatin administration in patients with lung cancer: a prospective multicenter trial.

Horinouchi H, Kubota K, Miyanaga A, Nakamichi S, Seike M, Gemma A, Yamane Y, Kurimoto F, Sakai H, Kanda S, Fujiwara Y, Nokihara H, Yamamoto N, Tamura T, Ohe Y.

ESMO Open. 2018 Jan 29;3(1):e000288. doi: 10.1136/esmoopen-2017-000288. eCollection 2018.

22.

Function and structure relationships of a β-1,2-glucooligosaccharide-degrading β-glucosidase.

Ishiguro R, Tanaka N, Abe K, Nakajima M, Maeda T, Miyanaga A, Takahashi Y, Sugimoto N, Nakai H, Taguchi H.

FEBS Lett. 2017 Dec;591(23):3926-3936. doi: 10.1002/1873-3468.12911. Epub 2017 Nov 24.

23.

Structure and function of polyketide biosynthetic enzymes: various strategies for production of structurally diverse polyketides.

Miyanaga A.

Biosci Biotechnol Biochem. 2017 Dec;81(12):2227-2236. doi: 10.1080/09168451.2017.1391687. Epub 2017 Nov 1. Review.

PMID:
29090652
24.

Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis.

Miyanaga A, Takayanagi R, Furuya T, Kawamata A, Itagaki T, Iwabuchi Y, Kanoh N, Kudo F, Eguchi T.

Chembiochem. 2017 Nov 2;18(21):2179-2187. doi: 10.1002/cbic.201700429. Epub 2017 Sep 18.

PMID:
28869713
25.

RT-PCR for Detecting ALK Translocations in Cytology Samples from Lung Cancer Patients.

Nakamichi S, Seike M, Miyanaga A, Chiba M, Matsuda K, Kobayashi K, Takahashi A, Takeuchi S, Minegishi Y, Kubota K, Gemma A.

Anticancer Res. 2017 Jun;37(6):3295-3299.

PMID:
28551680
26.

Structural analysis of the dual-function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an α,β-unsaturated thioester.

Chisuga T, Miyanaga A, Kudo F, Eguchi T.

J Biol Chem. 2017 Jun 30;292(26):10926-10937. doi: 10.1074/jbc.M117.792549. Epub 2017 May 18.

27.

The ternary complex structure of d-mandelate dehydrogenase with NADH and anilino(oxo)acetate.

Furukawa N, Miyanaga A, Nakajima M, Taguchi H.

Biochem Biophys Res Commun. 2017 May 6;486(3):665-670. doi: 10.1016/j.bbrc.2017.03.088. Epub 2017 Mar 19.

PMID:
28327357
28.

Biochemical characterization and structural insight into aliphatic β-amino acid adenylation enzymes IdnL1 and CmiS6.

Cieślak J, Miyanaga A, Takaku R, Takaishi M, Amagai K, Kudo F, Eguchi T.

Proteins. 2017 Jul;85(7):1238-1247. doi: 10.1002/prot.25284. Epub 2017 Mar 29.

PMID:
28316096
29.

Biochemical and structural analyses of a bacterial endo-β-1,2-glucanase reveal a new glycoside hydrolase family.

Abe K, Nakajima M, Yamashita T, Matsunaga H, Kamisuki S, Nihira T, Takahashi Y, Sugimoto N, Miyanaga A, Nakai H, Arakawa T, Fushinobu S, Taguchi H.

J Biol Chem. 2017 May 5;292(18):7487-7506. doi: 10.1074/jbc.M116.762724. Epub 2017 Mar 7.

30.

Mechanistic insight into the substrate specificity of 1,2-β-oligoglucan phosphorylase from Lachnoclostridium phytofermentans.

Nakajima M, Tanaka N, Furukawa N, Nihira T, Kodutsumi Y, Takahashi Y, Sugimoto N, Miyanaga A, Fushinobu S, Taguchi H, Nakai H.

Sci Rep. 2017 Feb 15;7:42671. doi: 10.1038/srep42671.

31.

Mechanisms of β-amino acid incorporation in polyketide macrolactam biosynthesis.

Miyanaga A, Kudo F, Eguchi T.

Curr Opin Chem Biol. 2016 Dec;35:58-64. doi: 10.1016/j.cbpa.2016.08.030. Epub 2016 Sep 10. Review.

PMID:
27619002
32.

Morphology Control of Metal-Organic Frameworks Based on Paddle-Wheel Units on Ion-Doped Polymer Substrate Using an Interfacial Growth Approach.

Tsuruoka T, Mantani K, Miyanaga A, Matsuyama T, Ohhashi T, Takashima Y, Akamatsu K.

Langmuir. 2016 Jun 21;32(24):6068-73. doi: 10.1021/acs.langmuir.6b01687. Epub 2016 Jun 9.

PMID:
27243413
33.

Interstitial lung disease associated with amrubicin chemotherapy in patients with lung cancer: a single institutional study.

Miura Y, Saito Y, Atsumi K, Takeuchi S, Miyanaga A, Mizutani H, Minegishi Y, Noro R, Seike M, Shinobu K, Kubota K, Gemma A.

Jpn J Clin Oncol. 2016 Jul;46(7):674-80. doi: 10.1093/jjco/hyw043. Epub 2016 May 9.

PMID:
27162319
34.

Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua.

Nakajima M, Yoshida R, Miyanaga A, Abe K, Takahashi Y, Sugimoto N, Toyoizumi H, Nakai H, Kitaoka M, Taguchi H.

PLoS One. 2016 Feb 17;11(2):e0148870. doi: 10.1371/journal.pone.0148870. eCollection 2016.

35.

Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.

Miyanaga A, Iwasawa S, Shinohara Y, Kudo F, Eguchi T.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1802-7. doi: 10.1073/pnas.1520042113. Epub 2016 Feb 1.

36.

Identification of the Fluvirucin B2 (Sch 38518) Biosynthetic Gene Cluster from Actinomadura fulva subsp. indica ATCC 53714: substrate Specificity of the β-Amino Acid Selective Adenylating Enzyme FlvN.

Miyanaga A, Hayakawa Y, Numakura M, Hashimoto J, Teruya K, Hirano T, Shin-Ya K, Kudo F, Eguchi T.

Biosci Biotechnol Biochem. 2016 May;80(5):935-41. doi: 10.1080/09168451.2015.1132155. Epub 2016 Jan 28.

PMID:
26818633
37.

miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells.

Nishijima N, Seike M, Soeno C, Chiba M, Miyanaga A, Noro R, Sugano T, Matsumoto M, Kubota K, Gemma A.

Int J Oncol. 2016 Mar;48(3):937-44. doi: 10.3892/ijo.2016.3331. Epub 2016 Jan 11.

38.

Parallel Post-Polyketide Synthase Modification Mechanism Involved in FD-891 Biosynthesis in Streptomyces graminofaciens A-8890.

Kudo F, Kawamura K, Furuya T, Yamanishi H, Motegi A, Komatsubara A, Numakura M, Miyanaga A, Eguchi T.

Chembiochem. 2016 Feb 2;17(3):233-8. doi: 10.1002/cbic.201500533. Epub 2016 Jan 8.

PMID:
26630077
39.

Mechanism-Based Trapping of the Quinonoid Intermediate by Using the K276R Mutant of PLP-Dependent 3-Aminobenzoate Synthase PctV in the Biosynthesis of Pactamycin.

Hirayama A, Miyanaga A, Kudo F, Eguchi T.

Chembiochem. 2015 Nov;16(17):2484-90. doi: 10.1002/cbic.201500426. Epub 2015 Oct 23.

PMID:
26426567
40.

Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.

Sugano T, Seike M, Noro R, Soeno C, Chiba M, Zou F, Nakamichi S, Nishijima N, Matsumoto M, Miyanaga A, Kubota K, Gemma A.

Mol Cancer Ther. 2015 Nov;14(11):2433-40. doi: 10.1158/1535-7163.MCT-15-0050. Epub 2015 Sep 8.

41.

[Anti-angiogenesis and molecular targeted therapies].

Miyanaga A, Gemma A.

Nihon Rinsho. 2015 Aug;73(8):1336-41. Review. Japanese.

PMID:
26281687
42.

Hippo pathway gene mutations in malignant mesothelioma: revealed by RNA and targeted exon sequencing.

Miyanaga A, Masuda M, Tsuta K, Kawasaki K, Nakamura Y, Sakuma T, Asamura H, Gemma A, Yamada T.

J Thorac Oncol. 2015 May;10(5):844-51. doi: 10.1097/JTO.0000000000000493.

43.

Effective Crizotinib schedule for an elderly patient with ALK rearranged non-small-cell lung cancer: a case report.

Fukuizumi A, Miyanaga A, Seike M, Kato Y, Nakamichi S, Chubachi K, Matsumoto M, Noro R, Minegishi Y, Kunugi S, Kubota K, Gemma A.

BMC Res Notes. 2015 Apr 23;8:165. doi: 10.1186/s13104-015-1126-8.

44.

Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer.

Matsumoto M, Seike M, Noro R, Soeno C, Sugano T, Takeuchi S, Miyanaga A, Kitamura K, Kubota K, Gemma A.

BMC Cancer. 2015 Apr 9;15:241. doi: 10.1186/s12885-015-1202-4.

45.

Genome mining of the hitachimycin biosynthetic gene cluster: involvement of a phenylalanine-2,3-aminomutase in biosynthesis.

Kudo F, Kawamura K, Uchino A, Miyanaga A, Numakura M, Takayanagi R, Eguchi T.

Chembiochem. 2015 Apr 13;16(6):909-14. doi: 10.1002/cbic.201500040. Epub 2015 Mar 18.

PMID:
25786909
46.

Diverse allosteric and catalytic functions of tetrameric d-lactate dehydrogenases from three Gram-negative bacteria.

Furukawa N, Miyanaga A, Togawa M, Nakajima M, Taguchi H.

AMB Express. 2014 Oct 28;4:76. doi: 10.1186/s13568-014-0076-1. eCollection 2014.

47.

Crystallization and preliminary X-ray diffraction analysis of Lin1840, a putative β-glucosidase from Listeria innocua.

Nakajima M, Yoshida R, Miyanaga A, Taguchi H.

Acta Crystallogr F Struct Biol Commun. 2014 Oct;70(Pt 10):1398-401. doi: 10.1107/S2053230X14018597. Epub 2014 Sep 25.

48.

The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.

Ikehara Y, Arai K, Furukawa N, Ohno T, Miyake T, Fushinobu S, Nakajima M, Miyanaga A, Taguchi H.

J Biol Chem. 2014 Nov 7;289(45):31550-64. doi: 10.1074/jbc.M114.599092. Epub 2014 Sep 25.

49.

The crystal structure of the adenylation enzyme VinN reveals a unique β-amino acid recognition mechanism.

Miyanaga A, Cieślak J, Shinohara Y, Kudo F, Eguchi T.

J Biol Chem. 2014 Nov 7;289(45):31448-57. doi: 10.1074/jbc.M114.602326. Epub 2014 Sep 22.

50.

MiR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesothelioma.

Yamamoto K, Seike M, Takeuchi S, Soeno C, Miyanaga A, Noro R, Minegishi Y, Kubota K, Gemma A.

Oncol Rep. 2014 Dec;32(6):2365-72. doi: 10.3892/or.2014.3481. Epub 2014 Sep 16.

PMID:
25231602

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