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Items: 1 to 50 of 88

1.

Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis.

Weinstabl H, Treu M, Rinnenthal J, Zahn SK, Ettmayer P, Bader G, Dahmann G, Kessler D, Rumpel K, Mischerikow N, Savarese F, Gerstberger T, Mayer M, Zoephel A, Schnitzer R, Sommergruber W, Martinelli P, Arnhof H, Peric-Simov B, Hofbauer KS, Garavel G, Scherbantin Y, Mitzner S, Fett TN, Scholz G, Bruchhaus J, Burkard M, Kousek R, Ciftci T, Sharps B, Schrenk A, Harrer C, Haering D, Wolkerstorfer B, Zhang X, Lv X, Du A, Li D, Li Y, Quant J, Pearson M, McConnell DB.

J Med Chem. 2019 Sep 12;62(17):7976-7997. doi: 10.1021/acs.jmedchem.9b00718. Epub 2019 Aug 14.

PMID:
31365252
2.

Cytokine adsorption is a promising tool in the therapy of hemophagocytic lymphohistiocytosis.

Frimmel S, Hinz M, Schipper J, Bogdanow S, Mitzner S, Koball S.

Int J Artif Organs. 2019 Nov;42(11):658-664. doi: 10.1177/0391398819857444. Epub 2019 Jun 26.

PMID:
31238776
3.

Thrombogenicity and long-term cytokine removal capability of a novel asymmetric triacetate membrane hemofilter.

Körtge A, Wild T, Heskamp B, Folk M, Mitzner S, Wasserkort R.

J Artif Organs. 2018 Dec;21(4):435-442. doi: 10.1007/s10047-018-1062-1. Epub 2018 Jul 24.

PMID:
30039457
4.

Impaired Cell Viability and Functionality of Hepatocytes After Incubation With Septic Plasma-Results of a Second Prospective Biosensor Study.

Sauer M, Haubner C, Richter G, Ehler J, Mencke T, Mitzner S, Margraf S, Altrichter J, Doß S, Nöldge-Schomburg G.

Front Immunol. 2018 Jun 25;9:1448. doi: 10.3389/fimmu.2018.01448. eCollection 2018.

5.

Effects of Bioreactor-Oxygenation During Extracorporeal Granulocytes Treatment in Septic Patients.

Sauer M, Richter G, Altrichter J, Wild T, Doß F, Mencke T, Ehler J, Doß S, Koch S, Schubert A, Nöldge-Schomburg G, Mitzner SR.

Ther Apher Dial. 2018 Aug;22(4):389-398. doi: 10.1111/1744-9987.12657. Epub 2018 Feb 8.

PMID:
29418067
6.

Extracorporeal Hemoperfusion as a Potential Therapeutic Option for Critical Accumulation of Rivaroxaban.

Koertge A, Wasserkort R, Wild T, Mitzner S.

Blood Purif. 2018;45(1-3):126-128. doi: 10.1159/000484923. Epub 2017 Dec 21. No abstract available.

7.

Treatment of the First Acute Relapse Following Therapeutic Plasma Exchange in Formerly Glucocorticosteroid-Unresponsive Multiple Sclerosis Patients-A Multicenter Study to Evaluate Glucocorticosteroid Responsiveness.

Ehler J, Blechinger S, Rommer PS, Koball S, Mitzner S, Hartung HP, Leutmezer F, Sauer M, Zettl UK.

Int J Mol Sci. 2017 Aug 11;18(8). pii: E1749. doi: 10.3390/ijms18081749.

8.

Hepatotoxicity of Antimycotics Used for Invasive Fungal Infections: In Vitro Results.

Doß S, Potschka H, Doß F, Mitzner S, Sauer M.

Biomed Res Int. 2017;2017:9658018. doi: 10.1155/2017/9658018. Epub 2017 Apr 4.

9.

Immunoadsorption as a Long-Term Therapy in Recurrent Focal Segmental Glomerulosclerosis After Renal Transplantation.

Frimmel S, Mitzner SR, Koball S.

Ther Apher Dial. 2017 Feb;21(1):108-109. doi: 10.1111/1744-9987.12487. Epub 2016 Dec 26. No abstract available.

PMID:
28025864
10.

Bioartificial Therapy of Sepsis: Changes of Norepinephrine-Dosage in Patients and Influence on Dynamic and Cell Based Liver Tests during Extracorporeal Treatments.

Sauer M, Altrichter J, Haubner C, Pertschy A, Wild T, Doß F, Mencke T, Thomsen M, Ehler J, Henschel J, Doß S, Koch S, Richter G, Nöldge-Schomburg G, Mitzner SR.

Biomed Res Int. 2016;2016:7056492. doi: 10.1155/2016/7056492. Epub 2016 Jun 28.

11.

Molecular adsorbent recirculating system and single-pass albumin dialysis in liver failure--a prospective, randomised crossover study.

Sponholz C, Matthes K, Rupp D, Backaus W, Klammt S, Karailieva D, Bauschke A, Settmacher U, Kohl M, Clemens MG, Mitzner S, Bauer M, Kortgen A.

Crit Care. 2016 Jan 4;20:2. doi: 10.1186/s13054-015-1159-3.

12.

Response to Therapeutic Plasma Exchange as a Rescue Treatment in Clinically Isolated Syndromes and Acute Worsening of Multiple Sclerosis: A Retrospective Analysis of 90 Patients.

Ehler J, Koball S, Sauer M, Mitzner S, Hickstein H, Benecke R, Zettl UK.

PLoS One. 2015 Aug 5;10(8):e0134583. doi: 10.1371/journal.pone.0134583. eCollection 2015.

13.

Pneumocystis pneumonia (PCP) and Pneumocystis jirovecii carriage in renal transplantation patients: a single-centre experience.

Maruschke M, Riebold D, Holtfreter MC, Sombetzki M, Mitzner S, Loebermann M, Reisinger EC, Hakenberg OW.

Wien Klin Wochenschr. 2014 Dec;126(23-24):762-6. doi: 10.1007/s00508-014-0608-3. Epub 2014 Sep 19.

PMID:
25234937
14.

First description of single-pass albumin dialysis combined with cytokine adsorption in fulminant liver failure and hemophagocytic syndrome resulting from generalized herpes simplex virus 1 infection.

Frimmel S, Schipper J, Henschel J, Yu TT, Mitzner SR, Koball S.

Liver Transpl. 2014 Dec;20(12):1523-4. doi: 10.1002/lt.24005. No abstract available.

15.

No sustained impact of intermittent extracorporeal liver support on thrombocyte time course in a randomized controlled albumin dialysis trial.

Klammt S, Mitzner SR, Reisinger EC, Stange J.

Ther Apher Dial. 2014 Oct;18(5):502-8. doi: 10.1111/1744-9987.12124. Epub 2014 Sep 4.

PMID:
25195684
16.

Therapeutic plasma exchange in glucocorticosteroid-unresponsive patients with Clinically Isolated Syndrome.

Ehler J, Koball S, Sauer M, Hickstein H, Mitzner S, Benecke R, Zettl UK.

Ther Apher Dial. 2014 Oct;18(5):489-96. doi: 10.1111/1744-9987.12176. Epub 2014 Mar 27.

PMID:
24674271
17.

AB0 incompatible kidney transplantation using unspecific immunoadsorption.

Hickstein H, Koball S, Lehmann R, Protzel C, Stein K, Mitzner S, Hakenberg O.

Transfus Apher Sci. 2014 Apr;50(2):263-6. doi: 10.1016/j.transci.2014.01.006. Epub 2014 Jan 17.

PMID:
24517873
18.

[Role of MARS® dialysis in acute-on-chronic liver failure].

Mitzner S.

Z Gastroenterol. 2013 Oct;51(10):1193-4. doi: 10.1055/s-0033-1350351. Epub 2013 Oct 11. German. No abstract available.

PMID:
24122382
19.

Establishment of a novel extracorporeal bowel model to study luminal approaches to treat inflammatory bowel disease.

Breitrück A, Sparmann G, Mitzner S, Kerkhoff C.

Dis Model Mech. 2013 Nov;6(6):1487-93. doi: 10.1242/dmm.011734. Epub 2013 Aug 14.

20.

Improvement of hemodynamic and inflammatory parameters by combined hemoadsorption and hemodiafiltration in septic shock: a case report.

Mitzner SR, Gloger M, Henschel J, Koball S.

Blood Purif. 2013;35(4):314-5. doi: 10.1159/000351206. Epub 2013 Jul 31. No abstract available.

PMID:
23920222
21.

Role of different replacement fluids during extracorporeal treatment in a pig model of sepsis.

Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR.

Ther Apher Dial. 2013 Feb;17(1):84-92. doi: 10.1111/j.1744-9987.2012.01103.x. Epub 2012 Aug 29.

PMID:
23379499
22.

Ciprofloxacin reduces the risk of hemolytic uremic syndrome in patients with Escherichia coli O104:H4-associated diarrhea.

Geerdes-Fenge HF, Löbermann M, Nürnberg M, Fritzsche C, Koball S, Henschel J, Höhn R, Schober HC, Mitzner S, Podbielski A, Reisinger EC.

Infection. 2013 Jun;41(3):669-73. doi: 10.1007/s15010-012-0387-6. Epub 2013 Jan 5.

PMID:
23292662
23.

Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial.

Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M, Saliba F, Sauerbruch T, Klammt S, Ockenga J, Pares A, Wendon J, Brünnler T, Kramer L, Mathurin P, de la Mata M, Gasbarrini A, Müllhaupt B, Wilmer A, Laleman W, Eefsen M, Sen S, Zipprich A, Tenorio T, Pavesi M, Schmidt HH, Mitzner S, Williams R, Arroyo V; RELIEF study group.

Hepatology. 2013 Mar;57(3):1153-62. doi: 10.1002/hep.26185. Epub 2013 Feb 15.

PMID:
23213075
24.

Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome: an analysis of the German STEC-HUS registry.

Kielstein JT, Beutel G, Fleig S, Steinhoff J, Meyer TN, Hafer C, Kuhlmann U, Bramstedt J, Panzer U, Vischedyk M, Busch V, Ries W, Mitzner S, Mees S, Stracke S, Nürnberger J, Gerke P, Wiesner M, Sucke B, Abu-Tair M, Kribben A, Klause N, Schindler R, Merkel F, Schnatter S, Dorresteijn EM, Samuelsson O, Brunkhorst R; Collaborators of the DGfN STEC-HUS registry.

Nephrol Dial Transplant. 2012 Oct;27(10):3807-15. doi: 10.1093/ndt/gfs394.

PMID:
23114903
25.

Plasma separation by centrifugation and subsequent plasma filtration: impact on survival in a pig model of sepsis.

Sauer M, Altrichter J, Mencke T, Klöhr S, Thomsen M, Kreutzer HJ, Nöldge-Schomburg G, Mitzner SR.

Ther Apher Dial. 2012 Jun;16(3):205-12. doi: 10.1111/j.1744-9987.2011.01055.x. Epub 2012 Mar 5.

PMID:
22607562
26.

Impaired cell functions of hepatocytes incubated with plasma of septic patients.

Sauer M, Haubner C, Mencke T, Nöldge-Schomburg G, Mitzner S, Altrichter J, Stange J.

Inflamm Res. 2012 Jun;61(6):609-16. doi: 10.1007/s00011-012-0451-9. Epub 2012 Feb 28.

PMID:
22370970
27.

Albumin-binding capacity (ABiC) is reduced in patients with chronic kidney disease along with an accumulation of protein-bound uraemic toxins.

Klammt S, Wojak HJ, Mitzner A, Koball S, Rychly J, Reisinger EC, Mitzner S.

Nephrol Dial Transplant. 2012 Jun;27(6):2377-83. doi: 10.1093/ndt/gfr616. Epub 2011 Nov 15.

PMID:
22086973
28.

Industrial stabilizers caprylate and N-acetyltryptophanate reduce the efficacy of albumin in liver patients.

Stange J, Stiffel M, Goetze A, Strube S, Gruenert J, Klammt S, Mitzner S, Koball S, Liebe S, Reisinger E.

Liver Transpl. 2011 Jun;17(6):705-9. doi: 10.1002/lt.22237.

29.
30.

Extracorporeal cell therapy of septic shock patients with donor granulocytes: a pilot study.

Altrichter J, Sauer M, Kaftan K, Birken T, Gloger D, Gloger M, Henschel J, Hickstein H, Klar E, Koball S, Pertschy A, Nöldge-Schomburg G, Vagts DA, Mitzner SR.

Crit Care. 2011;15(2):R82. doi: 10.1186/cc10076. Epub 2011 Mar 3.

31.

Acute functional neurotoxicity of lanthanum(III) in primary cortical networks.

Gramowski A, Jügelt K, Schröder OH, Weiss DG, Mitzner S.

Toxicol Sci. 2011 Mar;120(1):173-83. doi: 10.1093/toxsci/kfq385. Epub 2010 Dec 22.

PMID:
21177771
32.

Neutrophil-derived circulating free DNA (cf-DNA/NETs), a potential prognostic marker for mortality in patients with severe burn injury.

Altrichter J, Zedler S, Kraft R, Faist E, Mitzner SR, Sauer M, Windolf J, Scholz M, Lögters T.

Eur J Trauma Emerg Surg. 2010 Dec;36(6):551-7. doi: 10.1007/s00068-010-0013-1. Epub 2010 Mar 17.

PMID:
26816310
33.

Atypical electrolyte kinetics during an emergency dialysis session in a patient with Leriche syndrome.

Koball S, Hickstein H, Führer A, Heller T, Stange J, Mitzner S.

Clin Nephrol. 2010 Dec;74(6):471-3.

PMID:
21084051
34.

Use of preconditioned human phagocytes for extracorporeal adsorption of viruses.

Oberender F, Oberender H, Altrichter J, Reisinger EC, Mitzner SR.

Antiviral Res. 2010 Aug;87(2):230-4. doi: 10.1016/j.antiviral.2010.05.007. Epub 2010 Jun 1.

PMID:
20546790
35.

Treatment of thyrotoxic crisis with plasmapheresis and single pass albumin dialysis: a case report.

Koball S, Hickstein H, Gloger M, Hinz M, Henschel J, Stange J, Mitzner S.

Artif Organs. 2010 Feb;34(2):E55-8. doi: 10.1111/j.1525-1594.2009.00924.x.

PMID:
20420590
36.

Levomethadone is poorly removed by the molecular adsorbents recirculating system.

Czock D, Keller F, Hameister J, Tiefenbach B, Mitzner S.

J Clin Psychopharmacol. 2009 Dec;29(6):622-4. doi: 10.1097/JCP.0b013e3181c28957. No abstract available.

PMID:
19910741
37.

Safety evaluation for a cell-based immune support system in an ex vivo rat model of gram-negative sepsis.

Sauer M, Altrichter J, Kreutzer HJ, Schmidt H, Nöldge-Schomburg G, Schmidt R, Mitzner SR.

Ther Apher Dial. 2009 Oct;13(5):444-50. doi: 10.1111/j.1744-9987.2009.00764.x.

PMID:
19788463
38.

Increase of octanoate concentrations during extracorporeal albumin dialysis treatments.

Klammt S, Koball S, Hickstein H, Gloger M, Henschel J, Mitzner S, Stange J, Reisinger EC.

Ther Apher Dial. 2009 Oct;13(5):437-43. doi: 10.1111/j.1744-9987.2009.00763.x.

PMID:
19788462
39.

Albumin dialysis molecular adsorbents recirculating system: impact of dialysate albumin concentration on detoxification efficacy.

Drexler K, Baustian C, Richter G, Ludwig J, Ramlow W, Mitzner S.

Ther Apher Dial. 2009 Oct;13(5):393-8. doi: 10.1111/j.1744-9987.2009.00757.x.

PMID:
19788455
40.

Liver support 2009: time for another revolution?

Mitzner SR, Kaplan AA.

Ther Apher Dial. 2009 Oct;13(5):381-3. doi: 10.1111/j.1744-9987.2009.00755.x. No abstract available.

PMID:
19788453
41.

Cost-effectiveness of the artificial liver support system MARS in patients with acute-on-chronic liver failure.

Hessel FP, Bramlage P, Wasem J, Mitzner SR.

Eur J Gastroenterol Hepatol. 2010 Feb;22(2):213-20. doi: 10.1097/MEG.0b013e3283314e48.

PMID:
19773666
42.

Albumin dialysis MARS: knowledge from 10 years of clinical investigation.

Mitzner SR, Stange J, Klammt S, Koball S, Hickstein H, Reisinger EC.

ASAIO J. 2009 Sep-Oct;55(5):498-502. doi: 10.1097/MAT.0b013e3181b37d86. Review.

PMID:
19730006
43.

The clinical value of neutrophil extracellular traps.

Lögters T, Margraf S, Altrichter J, Cinatl J, Mitzner S, Windolf J, Scholz M.

Med Microbiol Immunol. 2009 Nov;198(4):211-9. doi: 10.1007/s00430-009-0121-x. Epub 2009 Aug 4. Review.

PMID:
19653000
44.

Biocompatibility assessment of peritoneal dialysis solutions with a new in vitro model of preconditioned human HL60 cells.

Koball S, Korten G, Stange J, Schmidt R, Mitzner S.

Artif Organs. 2009 Jul;33(7):544-50. doi: 10.1111/j.1525-1594.2009.00735.x.

PMID:
19566731
45.

Extracorporeal cell therapy with granulocytes in a pig model of Gram-positive sepsis.

Sauer M, Altrichter J, Kreutzer HJ, Lögters T, Scholz M, Nöldge-Schomburg G, Schmidt R, Mitzner SR.

Crit Care Med. 2009 Feb;37(2):606-13. doi: 10.1097/CCM.0b013e318194aa77.

PMID:
19114920
46.

Improvement of impaired albumin binding capacity in acute-on-chronic liver failure by albumin dialysis.

Klammt S, Mitzner SR, Stange J, Loock J, Heemann U, Emmrich J, Reisinger EC, Schmidt R.

Liver Transpl. 2008 Sep;14(9):1333-9. doi: 10.1002/lt.21504.

47.

Albumin dialysis: an update.

Mitzner SR.

Curr Opin Nephrol Hypertens. 2007 Nov;16(6):589-95. Review.

PMID:
18089976
48.

Albumin-binding function is reduced in patients with decompensated cirrhosis and correlates inversely with severity of liver disease assessed by model for end-stage liver disease.

Klammt S, Mitzner S, Stange J, Brinkmann B, Drewelow B, Emmrich J, Liebe S, Schmidt R.

Eur J Gastroenterol Hepatol. 2007 Mar;19(3):257-63.

PMID:
17301654
49.

Albumin regeneration in liver support-comparison of different methods.

Mitzner S, Klammt S, Stange J, Schmidt R.

Ther Apher Dial. 2006 Apr;10(2):108-17. Review. Erratum in: Ther Apher Dial. 2006 Dec;10(6):518.

PMID:
16684211
50.

Drain the brain: albumin dialysis for intracranial hypertension.

Mitzner SR.

Crit Care Med. 2006 Jan;34(1):254-5. No abstract available.

PMID:
16374193

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