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Items: 25

1.

Tertiary Lymphoid Organs in Central Nervous System Autoimmunity.

Mitsdoerffer M, Peters A.

Front Immunol. 2016 Oct 25;7:451. eCollection 2016. Review.

2.

IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis.

Lee Y, Mitsdoerffer M, Xiao S, Gu G, Sobel RA, Kuchroo VK.

J Clin Invest. 2015 Nov 2;125(11):4011-20. doi: 10.1172/JCI75933. Epub 2015 Sep 28.

3.

IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1.

Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A, Korn T.

Nat Commun. 2014 May 6;5:3770. doi: 10.1038/ncomms4770.

PMID:
24796719
4.

Th17 cells in central nervous system autoimmunity.

Sie C, Korn T, Mitsdoerffer M.

Exp Neurol. 2014 Dec;262 Pt A:18-27. doi: 10.1016/j.expneurol.2014.03.009. Epub 2014 Mar 27. Review.

PMID:
24681001
5.

Immunology of neuromyelitis optica: a T cell-B cell collaboration.

Mitsdoerffer M, Kuchroo V, Korn T.

Ann N Y Acad Sci. 2013 Apr;1283:57-66. doi: 10.1111/nyas.12118. Review.

6.

Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation.

Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK.

Immunity. 2011 Dec 23;35(6):986-96. doi: 10.1016/j.immuni.2011.10.015. Epub 2011 Dec 15.

7.

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis.

Quintana FJ, Murugaiyan G, Farez MF, Mitsdoerffer M, Tukpah AM, Burns EJ, Weiner HL.

Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20768-73. doi: 10.1073/pnas.1009201107. Epub 2010 Nov 10.

8.

Proinflammatory T helper type 17 cells are effective B-cell helpers.

Mitsdoerffer M, Lee Y, Jäger A, Kim HJ, Korn T, Kolls JK, Cantor H, Bettelli E, Kuchroo VK.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14292-7. doi: 10.1073/pnas.1009234107. Epub 2010 Jul 26.

9.

IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections.

Riol-Blanco L, Lazarevic V, Awasthi A, Mitsdoerffer M, Wilson BS, Croxford A, Waisman A, Kuchroo VK, Glimcher LH, Oukka M.

J Immunol. 2010 Feb 15;184(4):1710-20. doi: 10.4049/jimmunol.0902796. Epub 2010 Jan 18.

10.

Immunological basis for the development of tissue inflammation and organ-specific autoimmunity in animal models of multiple sclerosis.

Korn T, Mitsdoerffer M, Kuchroo VK.

Results Probl Cell Differ. 2010;51:43-74. doi: 10.1007/400_2008_17. Review.

PMID:
19513635
11.

New pieces in the puzzle: how does interferon-beta really work in multiple sclerosis?

Mitsdoerffer M, Kuchroo V.

Ann Neurol. 2009 May;65(5):487-8. doi: 10.1002/ana.21722. No abstract available.

PMID:
19479722
12.

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells.

Bauquet AT, Jin H, Paterson AM, Mitsdoerffer M, Ho IC, Sharpe AH, Kuchroo VK.

Nat Immunol. 2009 Feb;10(2):167-75. doi: 10.1038/ni.1690. Epub 2008 Dec 21.

13.

IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells.

Korn T, Mitsdoerffer M, Croxford AL, Awasthi A, Dardalhon VA, Galileos G, Vollmar P, Stritesky GL, Kaplan MH, Waisman A, Kuchroo VK, Oukka M.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18460-5. doi: 10.1073/pnas.0809850105. Epub 2008 Nov 17.

14.

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells.

Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK.

Nat Immunol. 2008 Dec;9(12):1347-55. doi: 10.1038/ni.1677. Epub 2008 Nov 9. Erratum in: Nat Immunol. 2009 May;10(5):551.

15.

Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-beta in vitro and in vivo: rationale for the therapy of multiple sclerosis.

Mitsdoerffer M, Schreiner B, Kieseier BC, Neuhaus O, Dichgans J, Hartung HP, Weller M, Wiendl H.

J Neuroimmunol. 2005 Feb;159(1-2):155-64. Epub 2004 Dec 28.

PMID:
15652415
16.
17.

Hide-and-seek in the brain: a role for HLA-G mediating immune privilege for glioma cells.

Wiendl H, Mitsdoerffer M, Weller M.

Semin Cancer Biol. 2003 Oct;13(5):343-51. Review.

PMID:
14708714
18.

Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis.

Wintterle S, Schreiner B, Mitsdoerffer M, Schneider D, Chen L, Meyermann R, Weller M, Wiendl H.

Cancer Res. 2003 Nov 1;63(21):7462-7.

19.

Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo.

Schreiner B, Wischhusen J, Mitsdoerffer M, Schneider D, Bornemann A, Melms A, Tolosa E, Weller M, Wiendl H.

Glia. 2003 Dec;44(3):296-301.

PMID:
14603470
20.

Express and protect yourself: the potential role of HLA-G on muscle cells and in inflammatory myopathies.

Wiendl H, Mitsdoerffer M, Weller M.

Hum Immunol. 2003 Nov;64(11):1050-6. Review.

PMID:
14602235
21.

Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies.

Wiendl H, Mitsdoerffer M, Schneider D, Chen L, Lochmüller H, Melms A, Weller M.

FASEB J. 2003 Oct;17(13):1892-4. Epub 2003 Aug 15.

PMID:
12923066
22.

The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis.

Wiendl H, Neuhaus O, Mehling M, Wintterle S, Schreiner B, Mitsdoerffer M, Wienhold W, Weissert R, Wessels J, Hartung HP, Weller M, Tolosa E, Melms A.

J Neuroimmunol. 2003 Jul;140(1-2):177-87.

PMID:
12864987
23.

Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies.

Wiendl H, Mitsdoerffer M, Schneider D, Melms A, Lochmuller H, Hohlfeld R, Weller M.

Brain. 2003 May;126(Pt 5):1026-35.

PMID:
12690043
24.

The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy.

Wiendl H, Mitsdoerffer M, Hofmeister V, Wischhusen J, Weiss EH, Dichgans J, Lochmuller H, Hohlfeld R, Melms A, Weller M.

Brain. 2003 Jan;126(Pt 1):176-85.

PMID:
12477705
25.

A functional role of HLA-G expression in human gliomas: an alternative strategy of immune escape.

Wiendl H, Mitsdoerffer M, Hofmeister V, Wischhusen J, Bornemann A, Meyermann R, Weiss EH, Melms A, Weller M.

J Immunol. 2002 May 1;168(9):4772-80.

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