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Items: 1 to 50 of 83

1.

Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.

Bonacina F, Coe D, Wang G, Longhi MP, Baragetti A, Moregola A, Garlaschelli K, Uboldi P, Pellegatta F, Grigore L, Da Dalt L, Annoni A, Gregori S, Xiao Q, Caruso D, Mitro N, Catapano AL, Marelli-Berg FM, Norata GD.

Nat Commun. 2018 Aug 6;9(1):3083. doi: 10.1038/s41467-018-05322-1.

2.

Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth.

Pacella I, Procaccini C, Focaccetti C, Miacci S, Timperi E, Faicchia D, Severa M, Rizzo F, Coccia EM, Bonacina F, Mitro N, Norata GD, Rossetti G, Ranzani V, Pagani M, Giorda E, Wei Y, Matarese G, Barnaba V, Piconese S.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6546-E6555. doi: 10.1073/pnas.1720113115. Epub 2018 Jun 25.

PMID:
29941600
3.

Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver.

Della Torre S, Mitro N, Meda C, Lolli F, Pedretti S, Barcella M, Ottobrini L, Metzger D, Caruso D, Maggi A.

Cell Metab. 2018 Aug 7;28(2):256-267.e5. doi: 10.1016/j.cmet.2018.05.021. Epub 2018 Jun 14.

4.

Mitochondria, lysosomes, and dysfunction: their meaning in neurodegeneration.

Audano M, Schneider A, Mitro N.

J Neurochem. 2018 May 27. doi: 10.1111/jnc.14471. [Epub ahead of print] Review.

PMID:
29804302
5.

Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage.

Collino A, Termanini A, Nicoli P, Diaferia G, Polletti S, Recordati C, Castiglioni V, Caruso D, Mitro N, Natoli G, Ghisletti S.

PLoS Genet. 2018 May 7;14(5):e1007380. doi: 10.1371/journal.pgen.1007380. eCollection 2018 May.

6.

PPAR Agonists and Metabolic Syndrome: An Established Role?

Botta M, Audano M, Sahebkar A, Sirtori CR, Mitro N, Ruscica M.

Int J Mol Sci. 2018 Apr 14;19(4). pii: E1197. doi: 10.3390/ijms19041197. Review.

7.

Zc3h10 is a novel mitochondrial regulator.

Audano M, Pedretti S, Cermenati G, Brioschi E, Diaferia GR, Ghisletti S, Cuomo A, Bonaldi T, Salerno F, Mora M, Grigore L, Garlaschelli K, Baragetti A, Bonacina F, Catapano AL, Norata GD, Crestani M, Caruso D, Saez E, De Fabiani E, Mitro N.

EMBO Rep. 2018 Apr;19(4). pii: e45531. doi: 10.15252/embr.201745531. Epub 2018 Mar 5.

PMID:
29507079
8.

Intermittent Fasting Applied in Combination with Rotenone Treatment Exacerbates Dopamine Neurons Degeneration in Mice.

Tatulli G, Mitro N, Cannata SM, Audano M, Caruso D, D'Arcangelo G, Lettieri-Barbato D, Aquilano K.

Front Cell Neurosci. 2018 Jan 17;12:4. doi: 10.3389/fncel.2018.00004. eCollection 2018.

9.

Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.

Pesaresi M, Giatti S, Spezzano R, Romano S, Diviccaro S, Borsello T, Mitro N, Caruso D, Garcia-Segura LM, Melcangi RC.

Biol Sex Differ. 2018 Jan 19;9(1):6. doi: 10.1186/s13293-018-0164-z.

10.

Fenofibrate attenuates cardiac and renal alterations in young salt-loaded spontaneously hypertensive stroke-prone rats through mitochondrial protection.

Castiglioni L, Pignieri A, Fiaschè M, Giudici M, Crestani M, Mitro N, Abbate M, Zoja C, Rottoli D, Foray C, Fiordaliso F, Guerrini U, Tremoli E, Sironi L, Gelosa P.

J Hypertens. 2018 May;36(5):1129-1146. doi: 10.1097/HJH.0000000000001651.

PMID:
29278547
11.

Diabetes induces mitochondrial dysfunction and alters cholesterol homeostasis and neurosteroidogenesis in the rat cerebral cortex.

Romano S, Mitro N, Giatti S, Diviccaro S, Pesaresi M, Spezzano R, Audano M, Garcia-Segura LM, Caruso D, Melcangi RC.

J Steroid Biochem Mol Biol. 2018 Apr;178:108-116. doi: 10.1016/j.jsbmb.2017.11.009. Epub 2017 Nov 26.

PMID:
29183767
12.

Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile.

Buratta S, Urbanelli L, Sagini K, Giovagnoli S, Caponi S, Fioretto D, Mitro N, Caruso D, Emiliani C.

PLoS One. 2017 Nov 28;12(11):e0188840. doi: 10.1371/journal.pone.0188840. eCollection 2017.

13.

Motor Deficits and Cerebellar Atrophy in Elovl5 Knock Out Mice.

Hoxha E, Gabriele RMC, Balbo I, Ravera F, Masante L, Zambelli V, Albergo C, Mitro N, Caruso D, Di Gregorio E, Brusco A, Borroni B, Tempia F.

Front Cell Neurosci. 2017 Oct 30;11:343. doi: 10.3389/fncel.2017.00343. eCollection 2017.

14.

In vitro and in vivo evaluation of silk fibroin functionalized with GABA and allopregnanolone for Schwann cell and neuron survival.

Gennari CG, Cilurzo F, Mitro N, Caruso D, Minghetti P, Magnaghi V.

Regen Med. 2018 Mar;13(2):141-157. doi: 10.2217/rme-2017-0102. Epub 2017 Nov 21.

PMID:
29160149
15.

Gender-related metabolomics and lipidomics: From experimental animal models to clinical evidence.

Audano M, Maldini M, De Fabiani E, Mitro N, Caruso D.

J Proteomics. 2018 Apr 30;178:82-91. doi: 10.1016/j.jprot.2017.11.001. Epub 2017 Nov 6. Review.

PMID:
29122727
16.

microRNA 221 Targets ADAM10 mRNA and is Downregulated in Alzheimer's Disease.

Manzine PR, Pelucchi S, Horst MA, Vale FAC, Pavarini SCI, Audano M, Mitro N, Di Luca M, Marcello E, Cominetti MR.

J Alzheimers Dis. 2018;61(1):113-123. doi: 10.3233/JAD-170592.

PMID:
29036829
17.

Docosahexaenoic acid is a beneficial replacement treatment for spinocerebellar ataxia 38.

Manes M, Alberici A, Di Gregorio E, Boccone L, Premi E, Mitro N, Pasolini MP, Pani C, Paghera B, Perani D, Orsi L, Costanzi C, Ferrero M, Zoppo A, Tempia F, Caruso D, Grassi M, Padovani A, Brusco A, Borroni B.

Ann Neurol. 2017 Oct;82(4):615-621. doi: 10.1002/ana.25059. Epub 2017 Oct 22.

18.

Neuroactive steroids and diabetic complications in the nervous system.

Giatti S, Mastrangelo R, D'Antonio M, Pesaresi M, Romano S, Diviccaro S, Caruso D, Mitro N, Melcangi RC.

Front Neuroendocrinol. 2018 Jan;48:58-69. doi: 10.1016/j.yfrne.2017.07.006. Epub 2017 Jul 21. Review.

PMID:
28739507
19.

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.

Ferrari A, Longo R, Fiorino E, Silva R, Mitro N, Cermenati G, Gilardi F, Desvergne B, Andolfo A, Magagnotti C, Caruso D, Fabiani E, Hiebert SW, Crestani M.

Nat Commun. 2017 Jul 21;8(1):93. doi: 10.1038/s41467-017-00182-7.

20.

The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells.

Castella B, Kopecka J, Sciancalepore P, Mandili G, Foglietta M, Mitro N, Caruso D, Novelli F, Riganti C, Massaia M.

Nat Commun. 2017 Jun 5;8:15663. doi: 10.1038/ncomms15663.

21.

Sterol regulatory element binding protein-1C knockout mice show altered neuroactive steroid levels in sciatic nerve.

Mitro N, Cermenati G, Audano M, Giatti S, Pesaresi M, Pedretti S, Spezzano R, Caruso D, Melcangi RC.

J Neurochem. 2017 Aug;142(3):420-428. doi: 10.1111/jnc.14063. Epub 2017 May 29.

22.

Liver ERα regulates AgRP neuronal activity in the arcuate nucleus of female mice.

Benedusi V, Della Torre S, Mitro N, Caruso D, Oberto A, Tronel C, Meda C, Maggi A.

Sci Rep. 2017 Apr 26;7(1):1194. doi: 10.1038/s41598-017-01393-0.

23.

Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals.

Mauro C, Smith J, Cucchi D, Coe D, Fu H, Bonacina F, Baragetti A, Cermenati G, Caruso D, Mitro N, Catapano AL, Ammirati E, Longhi MP, Okkenhaug K, Norata GD, Marelli-Berg FM.

Cell Metab. 2017 Mar 7;25(3):593-609. doi: 10.1016/j.cmet.2017.01.008. Epub 2017 Feb 9.

24.

Diabetes alters myelin lipid profile in rat cerebral cortex: Protective effects of dihydroprogesterone.

Cermenati G, Giatti S, Audano M, Pesaresi M, Spezzano R, Caruso D, Mitro N, Melcangi RC.

J Steroid Biochem Mol Biol. 2017 Apr;168:60-70. doi: 10.1016/j.jsbmb.2017.02.002. Epub 2017 Feb 3.

PMID:
28167298
25.

Short-term effects of diabetes on neurosteroidogenesis in the rat hippocampus.

Romano S, Mitro N, Diviccaro S, Spezzano R, Audano M, Garcia-Segura LM, Caruso D, Melcangi RC.

J Steroid Biochem Mol Biol. 2017 Mar;167:135-143. doi: 10.1016/j.jsbmb.2016.11.019. Epub 2016 Nov 23.

PMID:
27890531
26.

Non-insulin anti-diabetic drugs: An update on pharmacological interactions.

Ruscica M, Baldessin L, Boccia D, Racagni G, Mitro N.

Pharmacol Res. 2017 Jan;115:14-24. doi: 10.1016/j.phrs.2016.11.005. Epub 2016 Nov 9. Review.

PMID:
27838511
27.

Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases.

Ferrari A, Fiorino E, Longo R, Barilla S, Mitro N, Cermenati G, Giudici M, Caruso D, Mai A, Guerrini U, De Fabiani E, Crestani M.

Int J Obes (Lond). 2017 Feb;41(2):289-298. doi: 10.1038/ijo.2016.191. Epub 2016 Oct 28.

PMID:
27795551
28.

FABP1 in wonderland.

Prinetti A, Mitro N.

J Neurochem. 2016 Aug;138(3):371-3. doi: 10.1111/jnc.13685. Epub 2016 Jun 22.

29.

Clinical and neuroradiological features of spinocerebellar ataxia 38 (SCA38).

Borroni B, Di Gregorio E, Orsi L, Vaula G, Costanzi C, Tempia F, Mitro N, Caruso D, Manes M, Pinessi L, Padovani A, Brusco A, Boccone L.

Parkinsonism Relat Disord. 2016 Jul;28:80-6. doi: 10.1016/j.parkreldis.2016.04.030. Epub 2016 Apr 27.

30.

An Essential Role for Liver ERα in Coupling Hepatic Metabolism to the Reproductive Cycle.

Della Torre S, Mitro N, Fontana R, Gomaraschi M, Favari E, Recordati C, Lolli F, Quagliarini F, Meda C, Ohlsson C, Crestani M, Uhlenhaut NH, Calabresi L, Maggi A.

Cell Rep. 2016 Apr 12;15(2):360-71. doi: 10.1016/j.celrep.2016.03.019. Epub 2016 Mar 31.

31.

Ring finger protein 10 is a novel synaptonuclear messenger encoding activation of NMDA receptors in hippocampus.

Dinamarca MC, Guzzetti F, Karpova A, Lim D, Mitro N, Musardo S, Mellone M, Marcello E, Stanic J, Samaddar T, Burguière A, Caldarelli A, Genazzani AA, Perroy J, Fagni L, Canonico PL, Kreutz MR, Gardoni F, Di Luca M.

Elife. 2016 Mar 15;5:e12430. doi: 10.7554/eLife.12430.

32.

Neuroactive steroids and the peripheral nervous system: An update.

Giatti S, Romano S, Pesaresi M, Cermenati G, Mitro N, Caruso D, Tetel MJ, Garcia-Segura LM, Melcangi RC.

Steroids. 2015 Nov;103:23-30. doi: 10.1016/j.steroids.2015.03.014. Epub 2015 Mar 28. Review.

PMID:
25824325
33.

Lack of sterol regulatory element binding factor-1c imposes glial Fatty Acid utilization leading to peripheral neuropathy.

Cermenati G, Audano M, Giatti S, Carozzi V, Porretta-Serapiglia C, Pettinato E, Ferri C, D'Antonio M, De Fabiani E, Crestani M, Scurati S, Saez E, Azcoitia I, Cavaletti G, Garcia-Segura LM, Melcangi RC, Caruso D, Mitro N.

Cell Metab. 2015 Apr 7;21(4):571-83. doi: 10.1016/j.cmet.2015.02.016. Epub 2015 Mar 26.

34.

Dihydrotestosterone as a Protective Agent in Chronic Experimental Autoimmune Encephalomyelitis.

Giatti S, Rigolio R, Romano S, Mitro N, Viviani B, Cavaletti G, Caruso D, Garcia-Segura LM, Melcangi RC.

Neuroendocrinology. 2015;101(4):296-308. doi: 10.1159/000381064. Epub 2015 Feb 26.

PMID:
25765436
35.

Olive oil phenolic extract regulates interleukin-8 expression by transcriptional and posttranscriptional mechanisms in Caco-2 cells.

Muto E, Dell'Agli M, Sangiovanni E, Mitro N, Fumagalli M, Crestani M, De Fabiani E, Caruso D.

Mol Nutr Food Res. 2015 Jun;59(6):1217-21. doi: 10.1002/mnfr.201400800. Epub 2015 Apr 27.

PMID:
25708117
36.

Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function.

Audano M, Ferrari A, Fiorino E, Kuenzl M, Caruso D, Mitro N, Crestani M, De Fabiani E.

Curr Genomics. 2014 Dec;15(6):436-56. doi: 10.2174/138920291506150106151119.

37.

The lipogenic regulator Sterol Regulatory Element Binding Factor-1c is required to maintain peripheral nerve structure and function.

Mitro N, Cermenati G, Audano M, Giatti S, D'Antonio M, Fabiani ED, Crestani M, Saez E, Azcoitia I, Cavaletti G, Garcia-Segura LM, Melcangi RC, Caruso D.

Springerplus. 2015 Jun 12;4(Suppl 1):L45. doi: 10.1186/2193-1801-4-S1-L45. eCollection 2015. No abstract available.

38.

Lipids in the nervous system: from biochemistry and molecular biology to patho-physiology.

Cermenati G, Mitro N, Audano M, Melcangi RC, Crestani M, De Fabiani E, Caruso D.

Biochim Biophys Acta. 2015 Jan;1851(1):51-60. doi: 10.1016/j.bbalip.2014.08.011. Epub 2014 Aug 20. Review.

PMID:
25150974
39.

ELOVL5 mutations cause spinocerebellar ataxia 38.

Di Gregorio E, Borroni B, Giorgio E, Lacerenza D, Ferrero M, Lo Buono N, Ragusa N, Mancini C, Gaussen M, Calcia A, Mitro N, Hoxha E, Mura I, Coviello DA, Moon YA, Tesson C, Vaula G, Couarch P, Orsi L, Duregon E, Papotti MG, Deleuze JF, Imbert J, Costanzi C, Padovani A, Giunti P, Maillet-Vioud M, Durr A, Brice A, Tempia F, Funaro A, Boccone L, Caruso D, Stevanin G, Brusco A.

Am J Hum Genet. 2014 Aug 7;95(2):209-17. doi: 10.1016/j.ajhg.2014.07.001. Epub 2014 Jul 24.

40.

Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy.

Mitro N, Cermenati G, Brioschi E, Abbiati F, Audano M, Giatti S, Crestani M, De Fabiani E, Azcoitia I, Garcia-Segura LM, Caruso D, Melcangi RC.

J Steroid Biochem Mol Biol. 2014 Sep;143:115-21. doi: 10.1016/j.jsbmb.2014.02.015. Epub 2014 Mar 4.

PMID:
24607810
41.

The sirtuin class of histone deacetylases: regulation and roles in lipid metabolism.

Fiorino E, Giudici M, Ferrari A, Mitro N, Caruso D, De Fabiani E, Crestani M.

IUBMB Life. 2014 Feb;66(2):89-99. doi: 10.1002/iub.1246. Epub 2014 Feb 3. Review.

42.

LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.

Gilardi F, Giudici M, Mitro N, Maschi O, Guerrini U, Rando G, Maggi A, Cermenati G, Laghezza A, Loiodice F, Pochetti G, Lavecchia A, Caruso D, De Fabiani E, Bamberg K, Crestani M.

J Biol Chem. 2014 Mar 7;289(10):6908-20. doi: 10.1074/jbc.M113.506394. Epub 2014 Jan 22.

43.

Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions.

Melcangi RC, Giatti S, Calabrese D, Pesaresi M, Cermenati G, Mitro N, Viviani B, Garcia-Segura LM, Caruso D.

Prog Neurobiol. 2014 Feb;113:56-69. doi: 10.1016/j.pneurobio.2013.07.006. Epub 2013 Aug 16. Review.

PMID:
23958466
44.

Liver X receptors, nervous system, and lipid metabolism.

Cermenati G, Brioschi E, Abbiati F, Melcangi RC, Caruso D, Mitro N.

J Endocrinol Invest. 2013 Jun;36(6):435-43. doi: 10.3275/8941. Epub 2013 Apr 18. Review.

PMID:
23609963
45.

Fluorescence resonance energy transfer techniques to study ligand-mediated interactions of PPARs with coregulators.

Mitro N, Godio C, Crestani M.

Methods Mol Biol. 2013;952:219-27. doi: 10.1007/978-1-62703-155-4_16.

PMID:
23100236
46.

Site-directed mutagenesis to study the role of specific amino acids in the ligand binding domain of PPARs.

Mitro N, Gilardi F, Giudici M, Godio C, Scotti E, Crestani M.

Methods Mol Biol. 2013;952:137-44. doi: 10.1007/978-1-62703-155-4_9.

PMID:
23100229
47.

Linking epigenetics to lipid metabolism: focus on histone deacetylases.

Ferrari A, Fiorino E, Giudici M, Gilardi F, Galmozzi A, Mitro N, Cermenati G, Godio C, Caruso D, De Fabiani E, Crestani M.

Mol Membr Biol. 2012 Nov;29(7):257-66. doi: 10.3109/09687688.2012.729094. Epub 2012 Oct 24. Review.

PMID:
23095054
48.

Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue.

Galmozzi A, Mitro N, Ferrari A, Gers E, Gilardi F, Godio C, Cermenati G, Gualerzi A, Donetti E, Rotili D, Valente S, Guerrini U, Caruso D, Mai A, Saez E, De Fabiani E, Crestani M.

Diabetes. 2013 Mar;62(3):732-42. doi: 10.2337/db12-0548. Epub 2012 Oct 15.

49.

Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes.

Campia I, Sala V, Kopecka J, Leo C, Mitro N, Costamagna C, Caruso D, Pescarmona G, Crepaldi T, Ghigo D, Bosia A, Riganti C.

Biochem J. 2012 Oct 15;447(2):301-11.

PMID:
22845468
50.

LXR and TSPO as new therapeutic targets to increase the levels of neuroactive steroids in the central nervous system of diabetic animals.

Mitro N, Cermenati G, Giatti S, Abbiati F, Pesaresi M, Calabrese D, Garcia-Segura LM, Caruso D, Melcangi RC.

Neurochem Int. 2012 May;60(6):616-21. doi: 10.1016/j.neuint.2012.02.025. Epub 2012 Mar 3.

PMID:
22406419

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