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Items: 1 to 50 of 165

1.

Systems analysis-based assessment of post-treatment adverse events in lymphatic filariasis.

Andersen BJ, Rosa BA, Kupritz J, Meite A, Serge T, Hertz MI, Curtis K, King CL, Mitreva M, Fischer PU, Weil GJ.

PLoS Negl Trop Dis. 2019 Sep 26;13(9):e0007697. doi: 10.1371/journal.pntd.0007697. eCollection 2019 Sep.

2.

Adaptive radiation of the flukes of the family Fasciolidae inferred from genome-wide comparisons of key species.

Choi YJ, Fontenla S, Fischer PU, Le TH, Costábile A, Blair D, Brindley PJ, Tort JF, Cabada MM, Mitreva M.

Mol Biol Evol. 2019 Sep 10. pii: msz204. doi: 10.1093/molbev/msz204. [Epub ahead of print]

PMID:
31501870
3.

Stunting Is Preceded by Intestinal Mucosal Damage and Microbiome Changes and Is Associated with Systemic Inflammation in a Cohort of Peruvian Infants.

Zambruni M, Ochoa TJ, Somasunderam A, Cabada MM, Morales ML, Mitreva M, Rosa BA, Acosta GJ, Vigo NI, Riveros M, Arango S, Durand D, Berends MN, Melby P, Utay NS.

Am J Trop Med Hyg. 2019 Nov;101(5):1009-1017. doi: 10.4269/ajtmh.18-0975.

PMID:
31482782
4.

Omics Driven Understanding of the Intestines of Parasitic Nematodes.

Jasmer DP, Rosa BA, Tyagi R, Mitreva M.

Front Genet. 2019 Jul 25;10:652. doi: 10.3389/fgene.2019.00652. eCollection 2019. Review.

5.

Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease.

Schwimmer JB, Johnson JS, Angeles JE, Behling C, Belt PH, Borecki I, Bross C, Durelle J, Goyal NP, Hamilton G, Holtz ML, Lavine JE, Mitreva M, Newton KP, Pan A, Simpson PM, Sirlin CB, Sodergren E, Tyagi R, Yates KP, Weinstock GM, Salzman NH.

Gastroenterology. 2019 Oct;157(4):1109-1122. doi: 10.1053/j.gastro.2019.06.028. Epub 2019 Jun 27.

PMID:
31255652
6.

Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics.

Tyagi R, Elfawal MA, Wildman SA, Helander J, Bulman CA, Sakanari J, Rosa BA, Brindley PJ, Janetka JW, Aroian RV, Mitreva M.

Sci Rep. 2019 Jun 24;9(1):9085. doi: 10.1038/s41598-019-45548-7.

7.

V1 and V2 Domains of HIV Envelope Contribute to CCR5 Antagonist Resistance.

Wu E, Du Y, Gao X, Zhang J, Martin J, Mitreva M, Ratner L.

J Virol. 2019 Apr 17;93(9). pii: e00050-19. doi: 10.1128/JVI.00050-19. Print 2019 May 1.

8.

The mixed model for the analysis of a repeated-measurement multivariate count data.

Martin I, Uh HW, Supali T, Mitreva M, Houwing-Duistermaat JJ.

Stat Med. 2019 May 30;38(12):2248-2268. doi: 10.1002/sim.8101. Epub 2019 Feb 13.

9.

Skin Ecology during Sebaceous Drought-How Skin Microbes Respond to Isotretinoin.

McCoy WH 4th, Otchere E, Rosa BA, Martin J, Mann CM, Mitreva M.

J Invest Dermatol. 2019 Mar;139(3):732-735. doi: 10.1016/j.jid.2018.09.023. Epub 2018 Oct 24. No abstract available.

PMID:
30579608
10.

Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties.

Leroux LP, Nasr M, Valanparambil R, Tam M, Rosa BA, Siciliani E, Hill DE, Zarlenga DS, Jaramillo M, Weinstock JV, Geary TG, Stevenson MM, Urban JF Jr, Mitreva M, Jardim A.

Sci Rep. 2018 Oct 29;8(1):15921. doi: 10.1038/s41598-018-34174-4.

11.

Publisher Correction: Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Nov;3(11):1327. doi: 10.1038/s41564-018-0281-9.

PMID:
30327492
12.

A tale of three kingdoms: members of the Phylum Nematoda independently acquired the detoxifying enzyme cyanase through horizontal gene transfer from plants and bacteria.

Zarlenga DS, Mitreva M, Thompson P, Tyagi R, Tuo W, Hoberg EP.

Parasitology. 2019 Apr;146(4):445-452. doi: 10.1017/S0031182018001701. Epub 2018 Oct 10.

13.

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Oct;3(10):1099-1108. doi: 10.1038/s41564-018-0245-0. Epub 2018 Sep 17. Erratum in: Nat Microbiol. 2018 Nov;3(11):1327.

14.

A novel role for C-C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis.

Dunlap MD, Howard N, Das S, Scott N, Ahmed M, Prince O, Rangel-Moreno J, Rosa BA, Martin J, Kaushal D, Kaplan G, Mitreva M, Kim KW, Randolph GJ, Khader SA.

Mucosal Immunol. 2018 Nov;11(6):1727-1742. doi: 10.1038/s41385-018-0071-y. Epub 2018 Aug 16.

15.

Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia.

Martin I, Djuardi Y, Sartono E, Rosa BA, Supali T, Mitreva M, Houwing-Duistermaat JJ, Yazdanbakhsh M.

PLoS Negl Trop Dis. 2018 Aug 9;12(8):e0006620. doi: 10.1371/journal.pntd.0006620. eCollection 2018 Aug.

16.

A Multi-Omics Database for Parasitic Nematodes and Trematodes.

Martin J, Tyagi R, Rosa BA, Mitreva M.

Methods Mol Biol. 2018;1757:371-397. doi: 10.1007/978-1-4939-7737-6_13.

17.

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.

Tyagi R, Maddirala AR, Elfawal M, Fischer C, Bulman CA, Rosa BA, Gao X, Chugani R, Zhou M, Helander J, Brindley PJ, Tseng CC, Greig IR, Sakanari J, Wildman SA, Aroian R, Janetka JW, Mitreva M.

ACS Infect Dis. 2018 Jul 13;4(7):1130-1145. doi: 10.1021/acsinfecdis.8b00090. Epub 2018 May 14.

18.

Improving eukaryotic genome annotation using single molecule mRNA sequencing.

Magrini V, Gao X, Rosa BA, McGrath S, Zhang X, Hallsworth-Pepin K, Martin J, Hawdon J, Wilson RK, Mitreva M.

BMC Genomics. 2018 Mar 1;19(1):172. doi: 10.1186/s12864-018-4555-7.

19.

Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia.

Rosa BA, Supali T, Gankpala L, Djuardi Y, Sartono E, Zhou Y, Fischer K, Martin J, Tyagi R, Bolay FK, Fischer PU, Yazdanbakhsh M, Mitreva M.

Microbiome. 2018 Feb 28;6(1):33. doi: 10.1186/s40168-018-0416-5.

20.

Tackling Hypotheticals in Helminth Genomes.

International Molecular Helminthology Annotation Network (IMHAN); IMHAN consortium authors include, Palevich N, Britton C, Kamenetzky L, Mitreva M, de Moraes Mourão M, Bennuru S, Quack T, Scholte LLS, Tyagi R, Slatko BE.

Trends Parasitol. 2018 Mar;34(3):179-183. doi: 10.1016/j.pt.2017.11.007. Epub 2017 Dec 14.

PMID:
29249363
21.

Insights Into Onchocerca volvulus Population Biology Through Multilocus Immunophenotyping.

Norice-Tra CT, Ribeiro J, Bennuru S, Fay MP, Tyagi R, Mitreva M, Nutman TB.

J Infect Dis. 2017 Sep 15;216(6):736-743. doi: 10.1093/infdis/jix394.

22.

Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria.

Dobbs KR, Embury P, Vulule J, Odada PS, Rosa BA, Mitreva M, Kazura JW, Dent AE.

JCI Insight. 2017 Sep 21;2(18). pii: 95352. doi: 10.1172/jci.insight.95352. eCollection 2017 Sep 21.

23.

Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta.

Choi YJ, Bisset SA, Doyle SR, Hallsworth-Pepin K, Martin J, Grant WN, Mitreva M.

PLoS Genet. 2017 Jun 23;13(6):e1006857. doi: 10.1371/journal.pgen.1006857. eCollection 2017 Jun.

24.

Variant in a common odorant-binding protein gene is associated with bitter sensitivity in people.

Tomassini Barbarossa I, Ozdener MH, Melania, Love-Gregory L, Mitreva M, Abumrad NA, Pepino MY.

Behav Brain Res. 2017 Jun 30;329:200-204. doi: 10.1016/j.bbr.2017.05.015. Epub 2017 May 6.

25.

Application of Taxonomic Modeling to Microbiota Data Mining for Detection of Helminth Infection in Global Populations.

Torbati ME, Mitreva M, Gopalakrishnan V.

Data (Basel). 2016 Dec;1(3). pii: 19. doi: 10.3390/data1030019. Epub 2016 Dec 13.

26.

Direct experimental manipulation of intestinal cells in Ascaris suum, with minor influences on the global transcriptome.

Rosa BA, McNulty SN, Mitreva M, Jasmer DP.

Int J Parasitol. 2017 Apr;47(5):271-279. doi: 10.1016/j.ijpara.2016.12.005. Epub 2017 Feb 20.

27.

Genome Sequence of Christensenella minuta DSM 22607T.

Rosa BA, Hallsworth-Pepin K, Martin J, Wollam A, Mitreva M.

Genome Announc. 2017 Jan 12;5(2). pii: e01451-16. doi: 10.1128/genomeA.01451-16.

28.

Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers.

McNulty SN, Tort JF, Rinaldi G, Fischer K, Rosa BA, Smircich P, Fontenla S, Choi YJ, Tyagi R, Hallsworth-Pepin K, Mann VH, Kammili L, Latham PS, Dell'Oca N, Dominguez F, Carmona C, Fischer PU, Brindley PJ, Mitreva M.

PLoS Genet. 2017 Jan 6;13(1):e1006537. doi: 10.1371/journal.pgen.1006537. eCollection 2017 Jan.

29.

Genomic diversity in Onchocerca volvulus and its Wolbachia endosymbiont.

Choi YJ, Tyagi R, McNulty SN, Rosa BA, Ozersky P, Martin J, Hallsworth-Pepin K, Unnasch TR, Norice CT, Nutman TB, Weil GJ, Fischer PU, Mitreva M.

Nat Microbiol. 2016 Nov 21;2:16207. doi: 10.1038/nmicrobiol.2016.207.

30.

Changes in duodenal tissue-associated microbiota following hookworm infection and consecutive gluten challenges in humans with coeliac disease.

Giacomin P, Zakrzewski M, Jenkins TP, Su X, Al-Hallaf R, Croese J, de Vries S, Grant A, Mitreva M, Loukas A, Krause L, Cantacessi C.

Sci Rep. 2016 Nov 9;6:36797. doi: 10.1038/srep36797.

31.

Genome Sequences of Nine Gram-Negative Vaginal Bacterial Isolates.

Deitzler GE, Ruiz MJ, Lu W, Weimer C, Park S, Robinson LS, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis WG, Lewis AL.

Genome Announc. 2016 Sep 29;4(5). pii: e00889-16. doi: 10.1128/genomeA.00889-16.

32.

Genome Sequences of 14 Firmicutes Strains Isolated from the Human Vagina.

Deitzler GE, Ruiz MJ, Weimer C, Park S, Robinson L, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis AL, Lewis WG.

Genome Announc. 2016 Sep 29;4(5). pii: e00888-16. doi: 10.1128/genomeA.00888-16.

33.

Genome Sequences of 11 Human Vaginal Actinobacteria Strains.

Lewis AL, Deitzler GE, Ruiz MJ, Weimer C, Park S, Robinson LS, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis WG.

Genome Announc. 2016 Sep 29;4(5). pii: e00887-16. doi: 10.1128/genomeA.00887-16.

34.

Genome Sequences of 12 Bacterial Isolates Obtained from the Urine of Pregnant Women.

Weimer CM, Deitzler GE, Robinson LS, Park S, Hallsworth-Pepin K, Wollam A, Mitreva M, Lewis WG, Lewis AL.

Genome Announc. 2016 Sep 29;4(5). pii: e00882-16. doi: 10.1128/genomeA.00882-16.

35.

The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates.

Wei J, Damania A, Gao X, Liu Z, Mejia R, Mitreva M, Strych U, Bottazzi ME, Hotez PJ, Zhan B.

Parasit Vectors. 2016 Sep 27;9(1):518.

36.

Conservation and diversification of the transcriptomes of adult Paragonimus westermani and P. skrjabini.

Li BW, McNulty SN, Rosa BA, Tyagi R, Zeng QR, Gu KZ, Weil GJ, Mitreva M.

Parasit Vectors. 2016 Sep 13;9:497. doi: 10.1186/s13071-016-1785-x.

37.

Downregulation of the Syk Signaling Pathway in Intestinal Dendritic Cells Is Sufficient To Induce Dendritic Cells That Inhibit Colitis.

Hang L, Blum AM, Kumar S, Urban JF Jr, Mitreva M, Geary TG, Jardim A, Stevenson MM, Lowell CA, Weinstock JV.

J Immunol. 2016 Oct 1;197(7):2948-57. doi: 10.4049/jimmunol.1600063. Epub 2016 Aug 24.

38.

Trichinella spiralis: Adaptation and parasitism.

Zarlenga D, Wang Z, Mitreva M.

Vet Parasitol. 2016 Nov 15;231:8-21. doi: 10.1016/j.vetpar.2016.07.003. Epub 2016 Jul 2.

39.

Evolution of coreceptor utilization to escape CCR5 antagonist therapy.

Zhang J, Gao X, Martin J, Rosa B, Chen Z, Mitreva M, Henrich T, Kuritzkes D, Ratner L.

Virology. 2016 Jul;494:198-214. doi: 10.1016/j.virol.2016.04.010. Epub 2016 Apr 26.

40.

Compartmentalization of functions and predicted miRNA regulation among contiguous regions of the nematode intestine.

Gao X, Tyagi R, Magrini V, Ly A, Jasmer DP, Mitreva M.

RNA Biol. 2017 Oct 3;14(10):1335-1352. doi: 10.1080/15476286.2016.1166333. Epub 2016 Mar 22.

41.

Dictyocaulus viviparus genome, variome and transcriptome elucidate lungworm biology and support future intervention.

McNulty SN, Strübe C, Rosa BA, Martin JC, Tyagi R, Choi YJ, Wang Q, Hallsworth Pepin K, Zhang X, Ozersky P, Wilson RK, Sternberg PW, Gasser RB, Mitreva M.

Sci Rep. 2016 Feb 9;6:20316. doi: 10.1038/srep20316.

42.

Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.

Wang Q, Heizer E, Rosa BA, Wildman SA, Janetka JW, Mitreva M.

Infect Genet Evol. 2016 Apr;39:201-211. doi: 10.1016/j.meegid.2016.01.025. Epub 2016 Jan 30.

43.

Gene diversity and genetic variation in lung flukes (genus Paragonimus).

Blair D, Nawa Y, Mitreva M, Doanh PN.

Trans R Soc Trop Med Hyg. 2016 Jan;110(1):6-12. doi: 10.1093/trstmh/trv101. Review.

PMID:
26740357
44.

Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis.

Monin L, Griffiths KL, Lam WY, Gopal R, Kang DD, Ahmed M, Rajamanickam A, Cruz-Lagunas A, Zúñiga J, Babu S, Kolls JK, Mitreva M, Rosa BA, Ramos-Payan R, Morrison TE, Murray PJ, Rangel-Moreno J, Pearce EJ, Khader SA.

J Clin Invest. 2015 Dec;125(12):4699-713. doi: 10.1172/JCI77378. Epub 2015 Nov 16.

45.

Pan-Nematoda Transcriptomic Elucidation of Essential Intestinal Functions and Therapeutic Targets With Broad Potential.

Wang Q, Rosa BA, Jasmer DP, Mitreva M.

EBioMedicine. 2015 Jul 29;2(9):1079-89. doi: 10.1016/j.ebiom.2015.07.030. eCollection 2015 Sep.

46.

mBLAST: Keeping up with the sequencing explosion for (meta)genome analysis.

Davis C, Kota K, Baldhandapani V, Gong W, Abubucker S, Becker E, Martin J, Wylie KM, Khetani R, Hudson ME, Weinstock GM, Mitreva M.

J Data Mining Genomics Proteomics. 2015 Aug;4(3). pii: 135. Epub 2013 Jul 31.

47.

An Integrated Multiomics Approach to Identify Candidate Antigens for Serodiagnosis of Human Onchocerciasis.

McNulty SN, Rosa BA, Fischer PU, Rumsey JM, Erdmann-Gilmore P, Curtis KC, Specht S, Townsend RR, Weil GJ, Mitreva M.

Mol Cell Proteomics. 2015 Dec;14(12):3224-33. doi: 10.1074/mcp.M115.051953. Epub 2015 Oct 15.

48.

The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia.

Muñoz JF, Gauthier GM, Desjardins CA, Gallo JE, Holder J, Sullivan TD, Marty AJ, Carmen JC, Chen Z, Ding L, Gujja S, Magrini V, Misas E, Mitreva M, Priest M, Saif S, Whiston EA, Young S, Zeng Q, Goldman WE, Mardis ER, Taylor JW, McEwen JG, Clay OK, Klein BS, Cuomo CA.

PLoS Genet. 2015 Oct 6;11(10):e1005493. doi: 10.1371/journal.pgen.1005493. eCollection 2015 Oct.

49.

Targeting Lysine Deacetylases (KDACs) in Parasites.

Wang Q, Rosa BA, Nare B, Powell K, Valente S, Rotili D, Mai A, Marshall GR, Mitreva M.

PLoS Negl Trop Dis. 2015 Sep 24;9(9):e0004026. doi: 10.1371/journal.pntd.0004026. eCollection 2015.

50.

Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects.

Giacomin P, Zakrzewski M, Croese J, Su X, Sotillo J, McCann L, Navarro S, Mitreva M, Krause L, Loukas A, Cantacessi C.

Sci Rep. 2015 Sep 18;5:13797. doi: 10.1038/srep13797.

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