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Items: 1 to 50 of 218

1.

Mechanistic study of transdermal delivery of macromolecules assisted by ionic liquids.

Qi QM, Mitragotri S.

J Control Release. 2019 Aug 26;311-312:162-169. doi: 10.1016/j.jconrel.2019.08.029. [Epub ahead of print]

PMID:
31465826
2.

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.

Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufès C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, Caputo F, Boisseau P, Crist RM, McNeil SE, Fadeel B, Tran L, Hansen SF, Hartmann NB, Clausen LPW, Skjolding LM, Baun A, Ågerstrand M, Gu Z, Lamprou DA, Hoskins C, Huang L, Song W, Cao H, Liu X, Jandt KD, Jiang W, Kim BYS, Wheeler KE, Chetwynd AJ, Lynch I, Moghimi SM, Nel A, Xia T, Weiss PS, Sarmento B, das Neves J, Santos HA, Santos L, Mitragotri S, Little S, Peer D, Amiji MM, Alonso MJ, Petri-Fink A, Balog S, Lee A, Drasler B, Rothen-Rutishauser B, Wilhelm S, Acar H, Harrison RG, Mao C, Mukherjee P, Ramesh R, McNally LR, Busatto S, Wolfram J, Bergese P, Ferrari M, Fang RH, Zhang L, Zheng J, Peng C, Du B, Yu M, Charron DM, Zheng G, Pastore C.

Nat Nanotechnol. 2019 Sep;14(9):902. doi: 10.1038/s41565-019-0538-3.

PMID:
31358944
3.

Shape effect in active targeting of nanoparticles to inflamed cerebral endothelium under static and flow conditions.

Da Silva-Candal A, Brown T, Krishnan V, Lopez-Loureiro I, Ávila-Gómez P, Pusuluri A, Pérez-Díaz A, Correa-Paz C, Hervella P, Castillo J, Mitragotri S, Campos F.

J Control Release. 2019 Jul 19;309:94-105. doi: 10.1016/j.jconrel.2019.07.026. [Epub ahead of print]

4.

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.

Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufès C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, Caputo F, Boisseau P, Crist RM, McNeil SE, Fadeel B, Tran L, Hansen SF, Hartmann NB, Clausen LPW, Skjolding LM, Baun A, Ågerstrand M, Gu Z, Lamprou DA, Hoskins C, Huang L, Song W, Cao H, Liu X, Jandt KD, Jiang W, Kim BYS, Wheeler KE, Chetwynd AJ, Lynch I, Moghimi SM, Nel A, Xia T, Weiss PS, Sarmento B, Neves JD, Santos HA, Santos L, Mitragotri S, Little S, Peer D, Amiji MM, Alonso MJ, Petri-Fink A, Balog S, Lee A, Drasler B, Rothen-Rutishauser B, Wilhelm S, Acar H, Harrison RG, Mao C, Mukherjee P, Ramesh R, McNally LR, Busatto S, Wolfram J, Bergese P, Ferrari M, Fang RH, Zhang L, Zheng J, Peng C, Du B, Yu M, Charron DM, Zheng G, Pastore C.

Nat Nanotechnol. 2019 Aug;14(8):811. doi: 10.1038/s41565-019-0523-x.

PMID:
31289407
5.

On the issue of transparency and reproducibility in nanomedicine.

Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufés C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, Caputo F, Boisseau P, Crist RM, McNeil SE, Fadeel B, Tran L, Hansen SF, Hartmann NB, Clausen LPW, Skjolding LM, Baun A, Ågerstrand M, Gu Z, Lamprou DA, Hoskins C, Huang L, Song W, Cao H, Liu X, Jandt KD, Jiang W, Kim BYS, Wheeler KE, Chetwynd AJ, Lynch I, Moghimi SM, Nel A, Xia T, Weiss PS, Sarmento B, das Neves J, Santos HA, Santos L, Mitragotri S, Little S, Peer D, Amiji MM, Alonso MJ, Petri-Fink A, Balog S, Lee A, Drasler B, Rothen-Rutishauser B, Wilhelm S, Acar H, Harrison RG, Mao C, Mukherjee P, Ramesh R, McNally LR, Busatto S, Wolfram J, Bergese P, Ferrari M, Fang RH, Zhang L, Zheng J, Peng C, Du B, Yu M, Charron DM, Zheng G, Pastore C.

Nat Nanotechnol. 2019 Jul;14(7):629-635. doi: 10.1038/s41565-019-0496-9. No abstract available. Erratum in: Nat Nanotechnol. 2019 Aug;14(8):811. Nat Nanotechnol. 2019 Sep;14(9):902.

PMID:
31270452
6.

Materials for Immunotherapy.

Shields CW 4th, Wang LL, Evans MA, Mitragotri S.

Adv Mater. 2019 Jun 28:e1901633. doi: 10.1002/adma.201901633. [Epub ahead of print] Review.

PMID:
31250498
7.

Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin.

Pusuluri A, Krishnan V, Wu D, Shields CW 4th, Wang LW, Mitragotri S.

Bioeng Transl Med. 2019 Jun 13;4(2):e10129. doi: 10.1002/btm2.10129. eCollection 2019 May.

8.

A microfluidic model of human brain (μHuB) for assessment of blood brain barrier.

Brown TD, Nowak M, Bayles AV, Prabhakarpandian B, Karande P, Lahann J, Helgeson ME, Mitragotri S.

Bioeng Transl Med. 2019 Jan 13;4(2):e10126. doi: 10.1002/btm2.10126. eCollection 2019 May.

9.

Design Principles of Ionic Liquids for Transdermal Drug Delivery.

Tanner EEL, Curreri AM, Balkaran JPR, Selig-Wober NC, Yang AB, Kendig C, Fluhr MP, Kim N, Mitragotri S.

Adv Mater. 2019 Jul;31(27):e1901103. doi: 10.1002/adma.201901103. Epub 2019 May 21.

PMID:
31112631
10.

Immunological consequences of chemotherapy: Single drugs, combination therapies and nanoparticle-based treatments.

Pusuluri A, Wu D, Mitragotri S.

J Control Release. 2019 Jul 10;305:130-154. doi: 10.1016/j.jconrel.2019.04.020. Epub 2019 Apr 17. Review.

PMID:
31004668
11.

Skin delivery of hyaluronic acid by the combined use of sponge spicules and flexible liposomes.

Zhang C, Zhang K, Zhang J, Ou H, Duan J, Zhang S, Wang D, Mitragotri S, Chen M.

Biomater Sci. 2019 Mar 26;7(4):1299-1310. doi: 10.1039/c8bm01555d.

PMID:
30821312
12.

Effect of Chemical Permeation Enhancers on Skin Permeability: In silico screening using Molecular Dynamics simulations.

Gupta R, Dwadasi BS, Rai B, Mitragotri S.

Sci Rep. 2019 Feb 6;9(1):1456. doi: 10.1038/s41598-018-37900-0.

13.

Intestinal iontophoresis from mucoadhesive patches: a strategy for oral delivery.

Banerjee A, Chen R, Arafin S, Mitragotri S.

J Control Release. 2019 Mar 10;297:71-78. doi: 10.1016/j.jconrel.2019.01.037. Epub 2019 Jan 29.

PMID:
30707901
14.

Nanocrystals: A perspective on translational research and clinical studies.

Jarvis M, Krishnan V, Mitragotri S.

Bioeng Transl Med. 2018 Dec 24;4(1):5-16. doi: 10.1002/btm2.10122. eCollection 2019 Jan. Review.

15.

Harnessing cells to deliver nanoparticle drugs to treat cancer.

Singh B, Mitragotri S.

Biotechnol Adv. 2019 Jan 11. pii: S0734-9750(19)30006-0. doi: 10.1016/j.biotechadv.2019.01.006. [Epub ahead of print] Review.

PMID:
30639928
16.

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers.

Zhao Z, Ukidve A, Krishnan V, Mitragotri S.

Adv Drug Deliv Rev. 2019 Mar 15;143:3-21. doi: 10.1016/j.addr.2019.01.002. Epub 2019 Jan 11. Review.

PMID:
30639257
17.

Shape-based separation of synthetic microparticles.

Mage PL, Csordas AT, Brown T, Klinger D, Eisenstein M, Mitragotri S, Hawker C, Soh HT.

Nat Mater. 2019 Jan;18(1):82-89. doi: 10.1038/s41563-018-0244-9. Epub 2018 Dec 10.

PMID:
30542094
18.

Treating Tumors at Low Drug Doses Using an Aptamer-Peptide Synergistic Drug Conjugate.

Pusuluri A, Krishnan V, Lensch V, Sarode A, Bunyan E, Vogus DR, Menegatti S, Soh HT, Mitragotri S.

Angew Chem Int Ed Engl. 2019 Jan 28;58(5):1437-1441. doi: 10.1002/anie.201812650. Epub 2018 Dec 21.

PMID:
30537284
19.

Non-invasive delivery strategies for biologics.

Anselmo AC, Gokarn Y, Mitragotri S.

Nat Rev Drug Discov. 2019 Jan;18(1):19-40. doi: 10.1038/nrd.2018.183. Epub 2018 Nov 30. Review.

PMID:
30498202
20.

Reply to Rogers and Gurau: Definitions of ionic liquids and deep eutectic solvents.

Banerjee A, Ibsen K, Brown T, Chen R, Agatemor C, Mitragotri S.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11000-E11001. doi: 10.1073/pnas.1815526115. Epub 2018 Nov 6. No abstract available.

21.

Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer.

Vaidya B, Parvathaneni V, Kulkarni NS, Shukla SK, Damon JK, Sarode A, Kanabar D, Garcia JV, Mitragotri S, Muth A, Gupta V.

Int J Biol Macromol. 2019 Feb 1;122:338-347. doi: 10.1016/j.ijbiomac.2018.10.181. Epub 2018 Oct 26.

PMID:
30401652
22.

Engineering clinical translation-Introduction to Special Issue Dedicated to 2017 Bioengineering and Translational Medicine Conference.

Kannan RM, Mitragotri S.

Bioeng Transl Med. 2018 Oct 8;3(3):185. doi: 10.1002/btm2.10115. eCollection 2018 Sep. No abstract available.

23.

Influence of particle size and shape on their margination and wall-adhesion: implications in drug delivery vehicle design across nano-to-micro scale.

Cooley M, Sarode A, Hoore M, Fedosov DA, Mitragotri S, Sen Gupta A.

Nanoscale. 2018 Aug 16;10(32):15350-15364. doi: 10.1039/c8nr04042g.

24.

Detachment of ligands from nanoparticle surface under flow and endothelial cell contact: Assessment using microfluidic devices.

Jarvis M, Arnold M, Ott J, Krishnan V, Pant K, Prabhakarpandian B, Mitragotri S.

Bioeng Transl Med. 2018 Apr 17;3(2):148-155. doi: 10.1002/btm2.10089. eCollection 2018 May.

25.

Engineering clinical translation-Introduction to Special Issue Dedicated to 2017 Bioengineering and Translational Medicine Conference.

Kannan RM, Mitragotri S.

Bioeng Transl Med. 2018 Jul 27;3(2):73. doi: 10.1002/btm2.10099. eCollection 2018 May. No abstract available.

26.

Transdermal insulin delivery using choline-based ionic liquids (CAGE).

Tanner EEL, Ibsen KN, Mitragotri S.

J Control Release. 2018 Sep 28;286:137-144. doi: 10.1016/j.jconrel.2018.07.029. Epub 2018 Jul 17.

PMID:
30026081
27.

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude.

Brenner JS, Pan DC, Myerson JW, Marcos-Contreras OA, Villa CH, Patel P, Hekierski H, Chatterjee S, Tao JQ, Parhiz H, Bhamidipati K, Uhler TG, Hood ED, Kiseleva RY, Shuvaev VS, Shuvaeva T, Khoshnejad M, Johnston I, Gregory JV, Lahann J, Wang T, Cantu E, Armstead WM, Mitragotri S, Muzykantov V.

Nat Commun. 2018 Jul 11;9(1):2684. doi: 10.1038/s41467-018-05079-7.

28.

Ionic liquids for oral insulin delivery.

Banerjee A, Ibsen K, Brown T, Chen R, Agatemor C, Mitragotri S.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7296-7301. doi: 10.1073/pnas.1722338115. Epub 2018 Jun 25.

29.

Macrophage-mediated delivery of light activated nitric oxide prodrugs with spatial, temporal and concentration control.

Evans MA, Huang PJ, Iwamoto Y, Ibsen KN, Chan EM, Hitomi Y, Ford PC, Mitragotri S.

Chem Sci. 2018 Mar 16;9(15):3729-3741. doi: 10.1039/c8sc00015h. eCollection 2018 Apr 21.

30.

Transdermal immunomodulation: Principles, advances and perspectives.

Zhao Z, Ukidve A, Dasgupta A, Mitragotri S.

Adv Drug Deliv Rev. 2018 Mar 1;127:3-19. doi: 10.1016/j.addr.2018.03.010. Epub 2018 Mar 29. Review.

PMID:
29604373
31.

Schedule dependent synergy of gemcitabine and doxorubicin: Improvement of in vitro efficacy and lack of in vitro-in vivo correlation.

Vogus DR, Pusuluri A, Chen R, Mitragotri S.

Bioeng Transl Med. 2018 Jan 19;3(1):49-57. doi: 10.1002/btm2.10082. eCollection 2018 Jan.

32.

Ionic liquids for addressing unmet needs in healthcare.

Agatemor C, Ibsen KN, Tanner EEL, Mitragotri S.

Bioeng Transl Med. 2018 Jan 19;3(1):7-25. doi: 10.1002/btm2.10083. eCollection 2018 Jan. Review.

33.

Nanoparticle Properties Modulate Their Attachment and Effect on Carrier Red Blood Cells.

Pan DC, Myerson JW, Brenner JS, Patel PN, Anselmo AC, Mitragotri S, Muzykantov V.

Sci Rep. 2018 Jan 25;8(1):1615. doi: 10.1038/s41598-018-19897-8.

34.

Microfluidic co-culture devices to assess penetration of nanoparticles into cancer cell mass.

Jarvis M, Arnold M, Ott J, Pant K, Prabhakarpandian B, Mitragotri S.

Bioeng Transl Med. 2017 Sep 26;2(3):268-277. doi: 10.1002/btm2.10079. eCollection 2017 Sep.

35.

Introduction to Special Issue: 2016 Translational Medicine and Bioengineering Conference.

Rege K, Mitragotri S.

Bioeng Transl Med. 2017 Jul 25;2(2):137-138. doi: 10.1002/btm2.10071. eCollection 2017 Jun. No abstract available.

36.

Influence of Particle Geometry on Gastrointestinal Transit and Absorption following Oral Administration.

Li D, Zhuang J, He H, Jiang S, Banerjee A, Lu Y, Wu W, Mitragotri S, Gan L, Qi J.

ACS Appl Mater Interfaces. 2017 Dec 13;9(49):42492-42502. doi: 10.1021/acsami.7b11821. Epub 2017 Nov 29.

PMID:
29148702
37.

Controlling Complex Nanoemulsion Morphology Using Asymmetric Cosurfactants for the Preparation of Polymer Nanocapsules.

Zhang M, Corona PT, Ruocco N, Alvarez D, Malo de Molina P, Mitragotri S, Helgeson ME.

Langmuir. 2018 Jan 23;34(3):978-990. doi: 10.1021/acs.langmuir.7b02843. Epub 2017 Nov 10.

PMID:
29087721
38.

Intestinal patch systems for oral drug delivery.

Banerjee A, Mitragotri S.

Curr Opin Pharmacol. 2017 Oct;36:58-65. doi: 10.1016/j.coph.2017.08.005. Epub 2017 Aug 30. Review.

PMID:
28850875
39.

A hyaluronic acid conjugate engineered to synergistically and sequentially deliver gemcitabine and doxorubicin to treat triple negative breast cancer.

Vogus DR, Evans MA, Pusuluri A, Barajas A, Zhang M, Krishnan V, Nowak M, Menegatti S, Helgeson ME, Squires TM, Mitragotri S.

J Control Release. 2017 Dec 10;267:191-202. doi: 10.1016/j.jconrel.2017.08.016. Epub 2017 Aug 18.

PMID:
28823957
40.

Skin Delivery of Hydrophilic Biomacromolecules Using Marine Sponge Spicules.

Zhang S, Ou H, Liu C, Zhang Y, Mitragotri S, Wang D, Chen M.

Mol Pharm. 2017 Sep 5;14(9):3188-3200. doi: 10.1021/acs.molpharmaceut.7b00468. Epub 2017 Aug 18.

PMID:
28763230
41.

Synthesis of Oil-Laden Poly(ethylene glycol) Diacrylate Hydrogel Nanocapsules from Double Nanoemulsions.

Zhang M, Nowak M, Malo de Molina P, Abramovitch M, Santizo K, Mitragotri S, Helgeson ME.

Langmuir. 2017 Jun 20;33(24):6116-6126. doi: 10.1021/acs.langmuir.7b01162. Epub 2017 Jun 12.

PMID:
28605186
42.

Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization.

Niu J, Lunn DJ, Pusuluri A, Yoo JI, O'Malley MA, Mitragotri S, Soh HT, Hawker CJ.

Nat Chem. 2017 Jun;9(6):537-545. doi: 10.1038/nchem.2713. Epub 2017 Jan 30.

PMID:
28537595
43.

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes.

Wibroe PP, Anselmo AC, Nilsson PH, Sarode A, Gupta V, Urbanics R, Szebeni J, Hunter AC, Mitragotri S, Mollnes TE, Moghimi SM.

Nat Nanotechnol. 2017 Jul;12(6):589-594. doi: 10.1038/nnano.2017.47. Epub 2017 Apr 10.

PMID:
28396605
44.

Transdermal Protein Delivery Using Choline and Geranate (CAGE) Deep Eutectic Solvent.

Banerjee A, Ibsen K, Iwao Y, Zakrewsky M, Mitragotri S.

Adv Healthc Mater. 2017 Aug;6(15). doi: 10.1002/adhm.201601411. Epub 2017 Mar 24.

PMID:
28337858
45.

Intestinal micropatches for oral insulin delivery.

Banerjee A, Wong J, Gogoi R, Brown T, Mitragotri S.

J Drug Target. 2017 Aug;25(7):608-615. doi: 10.1080/1061186X.2017.1300664. Epub 2017 Mar 19.

PMID:
28266884
46.

Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond.

Mitragotri S, Lammers T, Bae YH, Schwendeman S, De Smedt S, Leroux JC, Peer D, Kwon IC, Harashima H, Kikuchi A, Oh YK, Torchilin V, Hennink W, Hanes J, Park K.

J Control Release. 2017 Jan 28;246:183-184. doi: 10.1016/j.jconrel.2017.01.011. No abstract available.

PMID:
28110715
47.

Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems.

Villa CH, Anselmo AC, Mitragotri S, Muzykantov V.

Adv Drug Deliv Rev. 2016 Nov 15;106(Pt A):88-103. doi: 10.1016/j.addr.2016.02.007. Epub 2016 Mar 3. Review.

48.

Therapeutic RNAi robed with ionic liquid moieties as a simple, scalable prodrug platform for treating skin disease.

Zakrewsky M, Mitragotri S.

J Control Release. 2016 Nov 28;242:80-88. doi: 10.1016/j.jconrel.2016.09.003. Epub 2016 Sep 6.

49.

Intestinal mucoadhesive devices for oral delivery of insulin.

Banerjee A, Lee J, Mitragotri S.

Bioeng Transl Med. 2016 Aug 19;1(3):338-346. doi: 10.1002/btm2.10015. eCollection 2016 Sep.

50.

Role of nanoparticle size, shape and surface chemistry in oral drug delivery.

Banerjee A, Qi J, Gogoi R, Wong J, Mitragotri S.

J Control Release. 2016 Sep 28;238:176-185. doi: 10.1016/j.jconrel.2016.07.051. Epub 2016 Jul 30.

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