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Association of daily physical activity with cognition and mood disorders in treatment-naive patients with early-stage Parkinson's disease.

Terashi H, Taguchi T, Ueta Y, Mitoma H, Aizawa H.

J Neural Transm (Vienna). 2019 Sep 30. doi: 10.1007/s00702-019-02085-x. [Epub ahead of print]


CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines.

Takaki-Kuwahara A, Arinobu Y, Miyawaki K, Yamada H, Tsuzuki H, Irino K, Ayano M, Kimoto Y, Mitoma H, Akahoshi M, Tsukamoto H, Horiuchi T, Niiro H, Akashi K.

Arthritis Res Ther. 2019 Aug 30;21(1):198. doi: 10.1186/s13075-019-1984-x.


Contribution of the Cerebellum to Predictive Motor Control and Its Evaluation in Ataxic Patients.

Kakei S, Lee J, Mitoma H, Tanaka H, Manto M, Hampe CS.

Front Hum Neurosci. 2019 Jun 26;13:216. doi: 10.3389/fnhum.2019.00216. eCollection 2019.


The Classification of Autosomal Recessive Cerebellar Ataxias: a Consensus Statement from the Society for Research on the Cerebellum and Ataxias Task Force.

Beaudin M, Matilla-Dueñas A, Soong BW, Pedroso JL, Barsottini OG, Mitoma H, Tsuji S, Schmahmann JD, Manto M, Rouleau GA, Klein C, Dupre N.

Cerebellum. 2019 Jul 2. doi: 10.1007/s12311-019-01052-2. [Epub ahead of print] Review.


Efficacy of istradefylline for gait disorders with freezing of gait in Parkinson's disease: A single-arm, open-label, prospective, multicenter study.

Iijima M, Orimo S, Terashi H, Suzuki M, Hayashi A, Shimura H, Mitoma H, Kitagawa K, Okuma Y.

Expert Opin Pharmacother. 2019 Aug;20(11):1405-1411. doi: 10.1080/14656566.2019.1614167. Epub 2019 May 28.


CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan.

Ayano M, Tsukamoto H, Mitoma H, Kimoto Y, Akahoshi M, Arinobu Y, Miyamoto T, Horiuchi T, Niiro H, Nagafuji K, Harada M, Akashi K.

Arthritis Res Ther. 2019 Jan 22;21(1):30. doi: 10.1186/s13075-019-1823-0.


Critical Thinking and Scientific Writing Skills of Non-Anglophone Medical Students: a Model of Training Course.

Barroga E, Mitoma H.

J Korean Med Sci. 2019 Jan 4;34(3):e18. doi: 10.3346/jkms.2019.34.e18. eCollection 2019 Jan 21. Review.


Improving Scientific Writing Skills and Publishing Capacity by Developing University-Based Editing System and Writing Programs.

Barroga E, Mitoma H.

J Korean Med Sci. 2018 Dec 28;34(1):e9. doi: 10.3346/jkms.2019.34.e9. eCollection 2019 Jan 7. Review.


Task Force Paper On Cerebellar Transplantation: Are We Ready to Treat Cerebellar Disorders with Cell Therapy?

Cendelin J, Buffo A, Hirai H, Magrassi L, Mitoma H, Sherrard R, Vozeh F, Manto M.

Cerebellum. 2019 Jun;18(3):575-592. doi: 10.1007/s12311-018-0999-1. Review.


The Era of Cerebellar Therapy.

Mitoma H, Manto M.

Curr Neuropharmacol. 2019;17(1):3-6. doi: 10.2174/1570159X1701181129111212.


Long-term efficacy of infliximab treatment and the predictors of treatment outcomes in patients with refractory uveitis associated with Behçet's disease.

Ueda S, Akahoshi M, Takeda A, Inoue Y, Omoto A, Ayano M, Kimoto Y, Mitoma H, Arinobu Y, Niiro H, Tsukamoto H, Horiuchi T, Hikita SI, Fukuhara T, Ishibashi T, Sonoda KH, Akashi K.

Eur J Rheumatol. 2018 Mar;5(1):9-15. doi: 10.5152/eurjrheum.2017.17068.


Anti-GAD Antibodies and the Cerebellum: Where Do We Stand?

Manto M, Mitoma H, Hampe CS.

Cerebellum. 2019 Apr;18(2):153-156. doi: 10.1007/s12311-018-0986-6.


Cerebellar Cortex as a Therapeutic Target for Neurostimulation.

van Dun K, Mitoma H, Manto M.

Cerebellum. 2018 Dec;17(6):777-787. doi: 10.1007/s12311-018-0976-8. Review.


Consensus paper: Decoding the Contributions of the Cerebellum as a Time Machine. From Neurons to Clinical Applications.

Bareš M, Apps R, Avanzino L, Breska A, D'Angelo E, Filip P, Gerwig M, Ivry RB, Lawrenson CL, Louis ED, Lusk NA, Manto M, Meck WH, Mitoma H, Petter EA.

Cerebellum. 2019 Apr;18(2):266-286. doi: 10.1007/s12311-018-0979-5.


Immune-mediated Cerebellar Ataxias: Practical Guidelines and Therapeutic Challenges.

Mitoma H, Manto M, Hampe CS.

Curr Neuropharmacol. 2019;17(1):33-58. doi: 10.2174/1570159X16666180917105033. Review.


Characteristics of apathy in treatment-naïve patients with Parkinson's disease.

Terashi H, Ueta Y, Kato H, Mitoma H, Aizawa H.

Int J Neurosci. 2019 Jan;129(1):16-21. doi: 10.1080/00207454.2018.1503184. Epub 2018 Nov 29.


Editorial: Advances in Therapies of Cerebellar Disorders.

Mitoma H, Manto M.

CNS Neurol Disord Drug Targets. 2018;17(3):157-160. doi: 10.2174/187152731703180619151532. No abstract available.


Neurotransplantation therapy.

Cendelin J, Mitoma H.

Handb Clin Neurol. 2018;155:379-391. doi: 10.1016/B978-0-444-64189-2.00025-1. Review.


Metabolic ataxias.

Ismail FY, Mitoma H, Fatemi A.

Handb Clin Neurol. 2018;155:117-127. doi: 10.1016/B978-0-444-64189-2.00008-1. Review.


Effects of tumor necrosis factor inhibitors and tocilizumab on the glycosylated hemoglobin levels in patients with rheumatoid arthritis; an observational study.

Otsuka Y, Kiyohara C, Kashiwado Y, Sawabe T, Nagano S, Kimoto Y, Ayano M, Mitoma H, Akahoshi M, Arinobu Y, Niiro H, Akashi K, Horiuchi T.

PLoS One. 2018 Apr 25;13(4):e0196368. doi: 10.1371/journal.pone.0196368. eCollection 2018.


Time Is Cerebellum.

Mitoma H, Manto M, Hampe CS.

Cerebellum. 2018 Aug;17(4):387-391. doi: 10.1007/s12311-018-0925-6.


Long-term Monitoring Gait Analysis Using a Wearable Device in Daily Lives of Patients with Parkinson's Disease: The Efficacy of Selegiline Hydrochloride for Gait Disturbance.

Iijima M, Mitoma H, Uchiyama S, Kitagawa K.

Front Neurol. 2017 Oct 24;8:542. doi: 10.3389/fneur.2017.00542. eCollection 2017.


Immune-mediated cerebellar ataxias: from bench to bedside.

Mitoma H, Manto M, Hampe CS.

Cerebellum Ataxias. 2017 Sep 21;4:16. doi: 10.1186/s40673-017-0073-7. eCollection 2017. Review.


Neurotransplantation Therapy and Cerebellar Reserve.

Cendelin J, Mitoma H, Manto M.

CNS Neurol Disord Drug Targets. 2018;17(3):172-183. doi: 10.2174/1871527316666170810114559. Review.


Quantitative Analysis of Motor Status in Parkinson's Disease Using Wearable Devices: From Methodological Considerations to Problems in Clinical Applications.

Suzuki M, Mitoma H, Yoneyama M.

Parkinsons Dis. 2017;2017:6139716. doi: 10.1155/2017/6139716. Epub 2017 May 18. Review.


Pathogenesis of systemic sclerosis-current concept and emerging treatments.

Furue M, Mitoma C, Mitoma H, Tsuji G, Chiba T, Nakahara T, Uchi H, Kadono T.

Immunol Res. 2017 Aug;65(4):790-797. doi: 10.1007/s12026-017-8926-y. Review.


Whole-Day Gait Monitoring in Patients with Alzheimer's Disease: A Relationship between Attention and Gait Cycle.

Higuma M, Sanjo N, Mitoma H, Yoneyama M, Yokota T.

J Alzheimers Dis Rep. 2017 Apr 28;1(1):1-8. doi: 10.3233/ADR-170001.


Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias.

Mitoma H, Manto M, Hampe CS.

J Immunol Res. 2017;2017:2913297. doi: 10.1155/2017/2913297. Epub 2017 Mar 12. Review.


The physiological basis of therapies for cerebellar ataxias.

Mitoma H, Manto M.

Ther Adv Neurol Disord. 2016 Sep;9(5):396-413. doi: 10.1177/1756285616648940. Epub 2016 May 20. Review.


Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes.

Tsuzuki H, Arinobu Y, Miyawaki K, Takaki A, Ota SI, Ota Y, Mitoma H, Akahoshi M, Mori Y, Iwasaki H, Niiro H, Tsukamoto H, Akashi K.

Immunology. 2017 Jan;150(1):64-73. doi: 10.1111/imm.12667. Epub 2016 Sep 30.


Molecular mechanisms of action of anti-TNF-α agents - Comparison among therapeutic TNF-α antagonists.

Mitoma H, Horiuchi T, Tsukamoto H, Ueda N.

Cytokine. 2018 Jan;101:56-63. doi: 10.1016/j.cyto.2016.08.014. Epub 2016 Aug 24. Review.


Prevalence of Autoantibodies and the Efficacy of Immunotherapy for Autoimmune Cerebellar Ataxia.

Nanri K, Okuma M, Sato S, Yoneda M, Taguchi T, Mitoma H, Yamada J, Unezaki S, Nagatani T, Otsubo S, Sugawara M, Tanaka N, Mizusawa H.

Intern Med. 2016;55(5):449-54. doi: 10.2169/internalmedicine.55.5156. Epub 2016 Mar 1.


Guidelines for treatment of immune-mediated cerebellar ataxias.

Mitoma H, Hadjivassiliou M, Honnorat J.

Cerebellum Ataxias. 2015 Nov 10;2:14. doi: 10.1186/s40673-015-0034-y. eCollection 2015. Review.


Overlooked Holmes' clinical signs: reevaluation by recent physiological findings.

Ishikawa T, Kakei S, Mitoma H.

Cerebellum Ataxias. 2015 Nov 6;2:13. doi: 10.1186/s40673-015-0033-z. eCollection 2015.


Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer.

Okugawa Y, Toiyama Y, Toden S, Mitoma H, Nagasaka T, Tanaka K, Inoue Y, Kusunoki M, Boland CR, Goel A.

Gut. 2017 Jan;66(1):107-117. doi: 10.1136/gutjnl-2015-309359. Epub 2015 Oct 15.


Ambulatory Gait Behavior in Patients With Dementia: A Comparison With Parkinson's Disease.

Yoneyama M, Mitoma H, Sanjo N, Higuma M, Terashi H, Yokota T.

IEEE Trans Neural Syst Rehabil Eng. 2016 Aug;24(8):817-26. doi: 10.1109/TNSRE.2015.2477856. Epub 2015 Sep 11.


Increased CD226 Expression on CD8+ T Cells Is Associated with Upregulated Cytokine Production and Endothelial Cell Injury in Patients with Systemic Sclerosis.

Ayano M, Tsukamoto H, Kohno K, Ueda N, Tanaka A, Mitoma H, Akahoshi M, Arinobu Y, Niiro H, Horiuchi T, Akashi K.

J Immunol. 2015 Aug 1;195(3):892-900. doi: 10.4049/jimmunol.1403046. Epub 2015 Jun 24.


Quality of life in Japanese female patients with systemic lupus erythematosus: Evaluation using the Short Form 36 Health Survey.

Furukawa M, Kiyohara C, Horiuchi T, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, Akashi K.

Mod Rheumatol. 2016;26(2):240-7. doi: 10.3109/14397595.2015.1060668. Epub 2015 Jul 20.


Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis.

Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, Ohta S, Kimoto Y, Akahoshi M, Arinobu Y, Niiro H, Tada Y, Horiuchi T, Akashi K.

Arthritis Res Ther. 2015 Feb 10;17:27. doi: 10.1186/s13075-015-0547-z.


Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotransmission and affect motor learning and behavioral functions.

Manto M, Honnorat J, Hampe CS, Guerra-Narbona R, López-Ramos JC, Delgado-García JM, Saitow F, Suzuki H, Yanagawa Y, Mizusawa H, Mitoma H.

Front Behav Neurosci. 2015 Mar 27;9:78. doi: 10.3389/fnbeh.2015.00078. eCollection 2015.


Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias.

Mitoma H, Adhikari K, Aeschlimann D, Chattopadhyay P, Hadjivassiliou M, Hampe CS, Honnorat J, Joubert B, Kakei S, Lee J, Manto M, Matsunaga A, Mizusawa H, Nanri K, Shanmugarajah P, Yoneda M, Yuki N.

Cerebellum. 2016 Apr;15(2):213-32. doi: 10.1007/s12311-015-0664-x. Review.


Generation mechanism of RANKL(+) effector memory B cells: relevance to the pathogenesis of rheumatoid arthritis.

Ota Y, Niiro H, Ota S, Ueki N, Tsuzuki H, Nakayama T, Mishima K, Higashioka K, Jabbarzadeh-Tabrizi S, Mitoma H, Akahoshi M, Arinobu Y, Kukita A, Yamada H, Tsukamoto H, Akashi K.

Arthritis Res Ther. 2016 Mar 16;18:67. doi: 10.1186/s13075-016-0957-6.


Human NLRP3 inflammasome senses multiple types of bacterial RNAs.

Sha W, Mitoma H, Hanabuchi S, Bao M, Weng L, Sugimoto N, Liu Y, Zhang Z, Zhong J, Sun B, Liu YJ.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16059-64. doi: 10.1073/pnas.1412487111. Epub 2014 Oct 29.


Kinematic analysis of 24-hour recording of walking pattern in patients with vascular parkinsonism.

Terashi H, Utsumi H, Ishimura Y, Aizawa H, Yoneyama M, Mitoma H.

Int J Neurosci. 2015;125(10):733-41. doi: 10.3109/00207454.2014.967350. Epub 2014 Dec 2.


The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation.

Weng L, Mitoma H, Trichot C, Bao M, Liu Y, Zhang Z, Liu YJ.

J Immunol. 2014 Oct 1;193(7):3676-82. doi: 10.4049/jimmunol.1401448. Epub 2014 Aug 29. Erratum in: J Immunol. 2014 Nov 15;193(10):5351. Tricot, Coline [Corrected to Trichot, Coline].


Gluten ataxia in Japan.

Nanri K, Mitoma H, Ihara M, Tanaka N, Taguchi T, Takeguchi M, Ishiko T, Mizusawa H.

Cerebellum. 2014 Oct;13(5):623-7. doi: 10.1007/s12311-014-0582-3.


[The utility of voxel-based morphometry in the diagnosis of spinocerebellar degeneration].

Tanaka N, Nanri K, Taguchi T, Tanaka N, Fujita T, Mitoma H, Kawata A, Mizusawa H.

Brain Nerve. 2014 Jun;66(6):699-704. Japanese.


Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system.

Sugimoto N, Mitoma H, Kim T, Hanabuchi S, Liu YJ.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7747-52. doi: 10.1073/pnas.1400139111. Epub 2014 May 12.


Human turnover dynamics during sleep: statistical behavior and its modeling.

Yoneyama M, Okuma Y, Utsumi H, Terashi H, Mitoma H.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Mar;89(3):032721. Epub 2014 Mar 31.


The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome.

Mitoma H, Hanabuchi S, Kim T, Bao M, Zhang Z, Sugimoto N, Liu YJ.

Immunity. 2013 Jul 25;39(1):123-35. doi: 10.1016/j.immuni.2013.07.001. Epub 2013 Jul 18.

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