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Items: 1 to 50 of 73

1.

VEGFR2 activation mediates the pro-angiogenic activity of BMP4.

Rezzola S, Di Somma M, Corsini M, Leali D, Ravelli C, Polli VAB, Grillo E, Presta M, Mitola S.

Angiogenesis. 2019 Jul 30. doi: 10.1007/s10456-019-09676-y. [Epub ahead of print]

PMID:
31363885
2.

Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migration.

Tobia C, Chiodelli P, Barbieri A, Buraschi S, Ferrari E, Mitola S, Borsani G, Guerra J, Presta M.

Front Immunol. 2019 May 15;10:1092. doi: 10.3389/fimmu.2019.01092. eCollection 2019.

3.

Silencing of pantothenate kinase 2 reduces endothelial cell angiogenesis.

Pagani F, Trivedi A, Khatri D, Zizioli D, Garrafa E, Mitola S, Finazzi D.

Mol Med Rep. 2018 Nov;18(5):4739-4746. doi: 10.3892/mmr.2018.9480. Epub 2018 Sep 13.

PMID:
30221726
4.

Claudin3 is localized outside the tight junctions in human carcinomas.

Corsini M, Ravaggi A, Odicino F, Santin AD, Ravelli C, Presta M, Romani C, Mitola S.

Oncotarget. 2018 Apr 6;9(26):18446-18453. doi: 10.18632/oncotarget.24858. eCollection 2018 Apr 6.

5.

Multi-physics interactions drive VEGFR2 relocation on endothelial cells.

Damioli V, Salvadori A, Beretta GP, Ravelli C, Mitola S.

Sci Rep. 2017 Dec 1;7(1):16700. doi: 10.1038/s41598-017-16786-4.

6.

Tumor angiogenesis revisited: Regulators and clinical implications.

Ronca R, Benkheil M, Mitola S, Struyf S, Liekens S.

Med Res Rev. 2017 Nov;37(6):1231-1274. doi: 10.1002/med.21452. Epub 2017 Jun 23. Review.

PMID:
28643862
7.

Role of Autophagy in HIV-1 Matrix Protein p17-Driven Lymphangiogenesis.

Mazzuca P, Marsico S, Schulze K, Mitola S, Pils MC, Giagulli C, Guzman CA, Caruso A, Caccuri F.

J Virol. 2017 Jul 27;91(16). pii: e00801-17. doi: 10.1128/JVI.00801-17. Print 2017 Aug 15.

8.

Inflammation and N-formyl peptide receptors mediate the angiogenic activity of human vitreous humour in proliferative diabetic retinopathy.

Rezzola S, Corsini M, Chiodelli P, Cancarini A, Nawaz IM, Coltrini D, Mitola S, Ronca R, Belleri M, Lista L, Rusciano D, De Rosa M, Pavone V, Semeraro F, Presta M.

Diabetologia. 2017 Apr;60(4):719-728. doi: 10.1007/s00125-016-4204-0. Epub 2017 Jan 13.

PMID:
28083635
9.

Cellular aspartyl proteases promote the unconventional secretion of biologically active HIV-1 matrix protein p17.

Caccuri F, Iaria ML, Campilongo F, Varney K, Rossi A, Mitola S, Schiarea S, Bugatti A, Mazzuca P, Giagulli C, Fiorentini S, Lu W, Salmona M, Caruso A.

Sci Rep. 2016 Dec 1;6:38027. doi: 10.1038/srep38027.

10.

Annexin 2A sustains glioblastoma cell dissemination and proliferation.

Maule F, Bresolin S, Rampazzo E, Boso D, Della Puppa A, Esposito G, Porcù E, Mitola S, Lombardi G, Accordi B, Tumino M, Basso G, Persano L.

Oncotarget. 2016 Aug 23;7(34):54632-54649. doi: 10.18632/oncotarget.10565.

11.

The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.

Porcù E, Persano L, Ronca R, Mitola S, Bortolozzi R, Romagnoli R, Oliva P, Basso G, Viola G.

Sci Rep. 2016 Jun 13;6:27886. doi: 10.1038/srep27886.

12.

Vascular disrupting activity of combretastatin analogues.

Porcù E, Salvador A, Primac I, Mitola S, Ronca R, Ravelli C, Bortolozzi R, Vedaldi D, Romagnoli R, Basso G, Viola G.

Vascul Pharmacol. 2016 Aug;83:78-89. doi: 10.1016/j.vph.2016.05.006. Epub 2016 May 25.

PMID:
27235861
13.

Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist.

Grillo E, Ravelli C, Corsini M, Ballmer-Hofer K, Zammataro L, Oreste P, Zoppetti G, Tobia C, Ronca R, Presta M, Mitola S.

Oncotarget. 2016 Jun 7;7(23):35353-68. doi: 10.18632/oncotarget.9286.

14.

Cortical Structure Alterations and Social Behavior Impairment in p50-Deficient Mice.

Bonini SA, Mastinu A, Maccarinelli G, Mitola S, Premoli M, La Rosa LR, Ferrari-Toninelli G, Grilli M, Memo M.

Cereb Cortex. 2016 Jun;26(6):2832-49. doi: 10.1093/cercor/bhw037. Epub 2016 Mar 5.

15.

A tool for the quantification of radial neo-vessels in chick chorioallantoic membrane angiogenic assays.

Gnutti A, Signoroni A, Leonardi R, Corsini M, Presta M, Mitola S.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:763-6. doi: 10.1109/EMBC.2015.7318474.

PMID:
26736374
16.

Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery.

Romani C, Cocco E, Bignotti E, Moratto D, Bugatti A, Todeschini P, Bandiera E, Tassi R, Zanotti L, Pecorelli S, Sartori E, Odicino FE, de Marco A, Santin AD, Ravaggi A, Mitola S.

Oncotarget. 2015 Oct 27;6(33):34617-28. doi: 10.18632/oncotarget.5315.

17.

β3 Integrin Promotes Long-Lasting Activation and Polarization of Vascular Endothelial Growth Factor Receptor 2 by Immobilized Ligand.

Ravelli C, Grillo E, Corsini M, Coltrini D, Presta M, Mitola S.

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2161-71. doi: 10.1161/ATVBAHA.115.306230. Epub 2015 Aug 20.

18.

Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma.

Faggi F, Chiarelli N, Colombi M, Mitola S, Ronca R, Madaro L, Bouche M, Poliani PL, Vezzoli M, Longhena F, Monti E, Salani B, Maggi D, Keller C, Fanzani A.

Lab Invest. 2015 Jun;95(6):585-602. doi: 10.1038/labinvest.2015.45. Epub 2015 Mar 30.

19.

Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Lopez-Cara C, Schiaffino Ortega S, Brancale A, Hamel E, Castagliuolo I, Mitola S, Ronca R, Bortolozzi R, Porcù E, Basso G, Viola G.

J Med Chem. 2015 Apr 9;58(7):3209-22. doi: 10.1021/acs.jmedchem.5b00155. Epub 2015 Mar 26.

20.

The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization.

Ruzzenenti P, Asperti M, Mitola S, Crescini E, Maccarinelli F, Gryzik M, Regoni M, Finazzi D, Arosio P, Poli M.

Biochim Biophys Acta. 2015 Jun;1850(6):1267-73. doi: 10.1016/j.bbagen.2015.02.016. Epub 2015 Mar 5.

PMID:
25749565
21.

Biosafe inertization of municipal solid waste incinerator residues by COSMOS technology.

Guarienti M, Gianoncelli A, Bontempi E, Moscoso Cardozo S, Borgese L, Zizioli D, Mitola S, Depero LE, Presta M.

J Hazard Mater. 2014 Aug 30;279:311-21. doi: 10.1016/j.jhazmat.2014.07.017. Epub 2014 Jul 18.

PMID:
25080155
22.

Phosphocaveolin-1 enforces tumor growth and chemoresistance in rhabdomyosarcoma.

Faggi F, Mitola S, Sorci G, Riuzzi F, Donato R, Codenotti S, Poliani PL, Cominelli M, Vescovi R, Rossi S, Calza S, Colombi M, Penna F, Costelli P, Perini I, Sampaolesi M, Monti E, Fanzani A.

PLoS One. 2014 Jan 10;9(1):e84618. doi: 10.1371/journal.pone.0084618. eCollection 2014.

23.

Cyclic adenosine monophosphate-response element-binding protein mediates the proangiogenic or proinflammatory activity of gremlin.

Corsini M, Moroni E, Ravelli C, Andrés G, Grillo E, Ali IH, Brazil DP, Presta M, Mitola S.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):136-45. doi: 10.1161/ATVBAHA.113.302517. Epub 2013 Nov 14.

PMID:
24233491
24.

Induction of death receptor 5 expression in tumor vasculature by perifosine restores the vascular disruption activity of TRAIL-expressing CD34(+) cells.

Giacomini A, Righi M, Cleris L, Locatelli SL, Mitola S, Daidone MG, Gianni AM, Carlo-Stella C.

Angiogenesis. 2013 Jul;16(3):707-22. doi: 10.1007/s10456-013-9348-7. Epub 2013 Apr 20.

PMID:
23605004
25.

Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine D3 receptors and Akt-mTORC1 signaling.

Collo G, Bono F, Cavalleri L, Plebani L, Mitola S, Merlo Pich E, Millan MJ, Zoli M, Maskos U, Spano P, Missale C.

Mol Pharmacol. 2013 Jun;83(6):1176-89. doi: 10.1124/mol.113.084863. Epub 2013 Mar 29.

PMID:
23543412
26.

TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis.

Porcù E, Viola G, Bortolozzi R, Persano L, Mitola S, Ronca R, Presta M, Romagnoli R, Baraldi PG, Basso G.

Angiogenesis. 2013 Jul;16(3):647-62. doi: 10.1007/s10456-013-9343-z. Epub 2013 Mar 2.

PMID:
23456551
27.

Involvement of αvβ3 integrin in gremlin-induced angiogenesis.

Ravelli C, Mitola S, Corsini M, Presta M.

Angiogenesis. 2013 Jan;16(1):235-43. doi: 10.1007/s10456-012-9309-6. Epub 2012 Sep 30.

PMID:
23053782
28.

Role of nanomechanics in canonical and noncanonical pro-angiogenic ligand/VEGF receptor-2 activation.

Maiolo D, Mitola S, Leali D, Oliviero G, Ravelli C, Bugatti A, Depero LE, Presta M, Bergese P.

J Am Chem Soc. 2012 Sep 5;134(35):14573-9. doi: 10.1021/ja305816p. Epub 2012 Aug 23.

PMID:
22860754
29.

Sphingosine-1-phosphate receptor-1 controls venous endothelial barrier integrity in zebrafish.

Tobia C, Chiodelli P, Nicoli S, Dell'era P, Buraschi S, Mitola S, Foglia E, van Loenen PB, Alewijnse AE, Presta M.

Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):e104-16. doi: 10.1161/ATVBAHA.112.250035. Epub 2012 Jul 26.

PMID:
22837470
30.

IL-12-dependent innate immunity arrests endothelial cells in G0-G1 phase by a p21(Cip1/Waf1)-mediated mechanism.

Napione L, Strasly M, Meda C, Mitola S, Alvaro M, Doronzo G, Marchiò S, Giraudo E, Primo L, Arese M, Bussolino F.

Angiogenesis. 2012 Dec;15(4):713-25. doi: 10.1007/s10456-012-9286-9. Epub 2012 Jul 15.

PMID:
22797886
31.

Anti-angiogenic activity of the flavonoid precursor 4-hydroxychalcone.

Varinska L, van Wijhe M, Belleri M, Mitola S, Perjesi P, Presta M, Koolwijk P, Ivanova L, Mojzis J.

Eur J Pharmacol. 2012 Sep 15;691(1-3):125-33. doi: 10.1016/j.ejphar.2012.06.017. Epub 2012 Jun 18.

PMID:
22721615
32.

Sialic acid associated with αvβ3 integrin mediates HIV-1 Tat protein interaction and endothelial cell proangiogenic activation.

Chiodelli P, Urbinati C, Mitola S, Tanghetti E, Rusnati M.

J Biol Chem. 2012 Jun 8;287(24):20456-66. doi: 10.1074/jbc.M111.337139. Epub 2012 Apr 23.

33.

Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin.

Chiodelli P, Mitola S, Ravelli C, Oreste P, Rusnati M, Presta M.

Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):e116-27. doi: 10.1161/ATVBAHA.111.235184. Epub 2011 Sep 15.

PMID:
21921258
34.

Nanoliter contact angle probes tumor angiogenic ligand-receptor protein interactions.

Olivero G, Maiolo D, Leali D, Federici S, Depero LE, Presta M, Mitola S, Bergese P.

Biosens Bioelectron. 2010 Dec 15;26(4):1571-5. doi: 10.1016/j.bios.2010.07.115. Epub 2010 Aug 13.

PMID:
20810271
35.

Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2.

Mitola S, Ravelli C, Moroni E, Salvi V, Leali D, Ballmer-Hofer K, Zammataro L, Presta M.

Blood. 2010 Nov 4;116(18):3677-80. doi: 10.1182/blood-2010-06-291930. Epub 2010 Jul 21.

PMID:
20660291
36.

Trichostatin A blocks type I interferon production by activated plasmacytoid dendritic cells.

Salvi V, Bosisio D, Mitola S, Andreoli L, Tincani A, Sozzani S.

Immunobiology. 2010 Sep-Oct;215(9-10):756-61. doi: 10.1016/j.imbio.2010.05.023. Epub 2010 Jun 4.

PMID:
20573419
37.

The COOH-terminal peptide of platelet factor-4 variant (CXCL4L1/PF-4var47-70) strongly inhibits angiogenesis and suppresses B16 melanoma growth in vivo.

Vandercappellen J, Liekens S, Bronckaers A, Noppen S, Ronsse I, Dillen C, Belleri M, Mitola S, Proost P, Presta M, Struyf S, Van Damme J.

Mol Cancer Res. 2010 Mar;8(3):322-34. doi: 10.1158/1541-7786.MCR-09-0176. Epub 2010 Mar 9.

38.

Fibroblast growth factor 2-antagonist activity of a long-pentraxin 3-derived anti-angiogenic pentapeptide.

Leali D, Bianchi R, Bugatti A, Nicoli S, Mitola S, Ragona L, Tomaselli S, Gallo G, Catello S, Rivieccio V, Zetta L, Presta M.

J Cell Mol Med. 2010 Aug;14(8):2109-21. doi: 10.1111/j.1582-4934.2009.00855.x. Epub 2010 Jul 20.

39.

Tumor necrosis factor-alpha in airway secretions from cystic fibrosis patients upregulate endothelial adhesion molecules and induce airway epithelial cell apoptosis: implications for cystic fibrosis lung disease.

Mitola S, Sorbello V, Ponte E, Copreni E, Mascia C, Bardessono M, Goia M, Biasi F, Conese M, Poli G, Bussolino F, De Rose V.

Int J Immunopathol Pharmacol. 2008 Oct-Dec;21(4):851-65.

PMID:
19144271
40.

Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity.

Rusnati M, Bugatti A, Mitola S, Leali D, Bergese P, Depero LE, Presta M.

Sensors (Basel). 2009;9(8):6471-503. doi: 10.3390/s90806471. Epub 2009 Aug 20.

41.

alphavbeta3 Integrin-dependent antiangiogenic activity of resveratrol stereoisomers.

Belleri M, Ribatti D, Savio M, Stivala LA, Forti L, Tanghetti E, Alessi P, Coltrini D, Bugatti A, Mitola S, Nicoli S, Vannini V, Presta M.

Mol Cancer Ther. 2008 Dec;7(12):3761-70. doi: 10.1158/1535-7163.MCT-07-2351.

42.

Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1.

Ponticelli S, Marasco D, Tarallo V, Albuquerque RJ, Mitola S, Takeda A, Stassen JM, Presta M, Ambati J, Ruvo M, De Falco S.

J Biol Chem. 2008 Dec 5;283(49):34250-9. doi: 10.1074/jbc.M806607200. Epub 2008 Oct 15.

43.

A pro-inflammatory signature mediates FGF2-induced angiogenesis.

Andrés G, Leali D, Mitola S, Coltrini D, Camozzi M, Corsini M, Belleri M, Hirsch E, Schwendener RA, Christofori G, Alcamí A, Presta M.

J Cell Mol Med. 2009 Aug;13(8B):2083-108. doi: 10.1111/j.1582-4934.2008.00415.x.

44.

Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm.

Mitola S, Moroni E, Ravelli C, Andres G, Belleri M, Presta M.

Blood. 2008 Aug 15;112(4):1154-7. doi: 10.1182/blood-2007-09-111450. Epub 2008 May 27.

PMID:
18505784
45.

Integrins: a flexible platform for endothelial vascular tyrosine kinase receptors.

Napione L, Cascone I, Mitola S, Serini G, Bussolino F.

Autoimmun Rev. 2007 Nov;7(1):18-22. doi: 10.1016/j.autrev.2007.03.007. Epub 2007 Apr 3. Review.

PMID:
17967720
46.

Dendritic cell-endothelial cell cross-talk in angiogenesis.

Sozzani S, Rusnati M, Riboldi E, Mitola S, Presta M.

Trends Immunol. 2007 Sep;28(9):385-92. Epub 2007 Aug 10. Review.

PMID:
17692569
47.

CEACAM1/VEGF cross-talk during neuroblastic tumour differentiation.

Poliani PL, Mitola S, Ravanini M, Ferrari-Toninelli G, D'Ippolito C, Notarangelo LD, Bercich L, Wagener C, Memo M, Presta M, Facchetti F.

J Pathol. 2007 Apr;211(5):541-9.

PMID:
17310502
48.

Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor.

Stabile H, Mitola S, Moroni E, Belleri M, Nicoli S, Coltrini D, Peri F, Pessi A, Orsatti L, Talamo F, Castronovo V, Waltregny D, Cotelli F, Ribatti D, Presta M.

Blood. 2007 Mar 1;109(5):1834-40. Epub 2006 Oct 31.

PMID:
17077323
49.

Regulation of dendritic cell migration and adaptive immune response by leukotriene B4 receptors: a role for LTB4 in up-regulation of CCR7 expression and function.

Del Prete A, Shao WH, Mitola S, Santoro G, Sozzani S, Haribabu B.

Blood. 2007 Jan 15;109(2):626-31. Epub 2006 Sep 19.

50.

Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine.

Mitola S, Belleri M, Urbinati C, Coltrini D, Sparatore B, Pedrazzi M, Melloni E, Presta M.

J Immunol. 2006 Jan 1;176(1):12-5.

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