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Items: 1 to 50 of 135

1.

Is frailty a stable predictor of mortality across time? Evidence from the Cognitive Function and Ageing Studies.

Mousa A, Savva GM, Mitnitski A, Rockwood K, Jagger C, Brayne C, Matthews FE.

Age Ageing. 2018 Sep 1;47(5):721-727. doi: 10.1093/ageing/afy077.

2.

Unifying aging and frailty through complex dynamical networks.

Rutenberg AD, Mitnitski AB, Farrell SG, Rockwood K.

Exp Gerontol. 2018 Jul 1;107:126-129. doi: 10.1016/j.exger.2017.08.027. Epub 2017 Aug 25. Review.

PMID:
28847723
3.

Frailty status at admission to hospital predicts multiple adverse outcomes.

Hubbard RE, Peel NM, Samanta M, Gray LC, Mitnitski A, Rockwood K.

Age Ageing. 2017 Sep 1;46(5):801-806. doi: 10.1093/ageing/afx081.

PMID:
28531254
4.

A Scoping Review of Frailty and Acute Care in Middle-Aged and Older Individuals with Recommendations for Future Research.

Hogan DB, Maxwell CJ, Afilalo J, Arora RC, Bagshaw SM, Basran J, Bergman H, Bronskill SE, Carter CA, Dixon E, Hemmelgarn B, Madden K, Mitnitski A, Rolfson D, Stelfox HT, Tam-Tham H, Wunsch H.

Can Geriatr J. 2017 Mar 31;20(1):22-37. doi: 10.5770/cgj.20.240. eCollection 2017 Mar. Review.

5.

Clinical meaningfulness of Alzheimer's Disease Assessment Scale-Cognitive subscale change in relation to goal attainment in patients on cholinesterase inhibitors.

Rockwood K, Howlett SE, Hoffman D, Schindler R, Mitnitski A.

Alzheimers Dement. 2017 Oct;13(10):1098-1106. doi: 10.1016/j.jalz.2017.02.005. Epub 2017 Mar 21.

PMID:
28341540
6.

Aging, frailty and complex networks.

Mitnitski AB, Rutenberg AD, Farrell S, Rockwood K.

Biogerontology. 2017 Aug;18(4):433-446. doi: 10.1007/s10522-017-9684-x. Epub 2017 Mar 2. Review.

PMID:
28255823
7.

A Frailty Index Based On Deficit Accumulation Quantifies Mortality Risk in Humans and in Mice.

Rockwood K, Blodgett JM, Theou O, Sun MH, Feridooni HA, Mitnitski A, Rose RA, Godin J, Gregson E, Howlett SE.

Sci Rep. 2017 Feb 21;7:43068. doi: 10.1038/srep43068.

8.

Frailty affects the initial treatment response and time to recovery of mobility in acutely ill older adults admitted to hospital.

Hatheway OL, Mitnitski A, Rockwood K.

Age Ageing. 2017 Nov 1;46(6):920-925. doi: 10.1093/ageing/afw257.

PMID:
28104595
9.

Network model of human aging: Frailty limits and information measures.

Farrell SG, Mitnitski AB, Rockwood K, Rutenberg AD.

Phys Rev E. 2016 Nov;94(5-1):052409. Epub 2016 Nov 18.

PMID:
27967091
10.

Socioeconomic gradient in health in Canada: Is the gap widening or narrowing?

Hajizadeh M, Mitnitski A, Rockwood K.

Health Policy. 2016 Sep;120(9):1040-50. doi: 10.1016/j.healthpol.2016.07.019. Epub 2016 Aug 3.

PMID:
27523425
11.

Changes in the Lethality of Frailty Over 30 Years: Evidence From Two Cohorts of 70-Year-Olds in Gothenburg Sweden.

Bäckman K, Joas E, Falk H, Mitnitski A, Rockwood K, Skoog I.

J Gerontol A Biol Sci Med Sci. 2017 Jul 1;72(7):945-950. doi: 10.1093/gerona/glw160.

12.

Corrigendum to "Trajectories of changes over twelve years in the health status of Canadians from late middle age" [Exp. Gerontol. 47/12 (2012) 893-899].

Mitnitski A, Song X, Rockwood K.

Exp Gerontol. 2016 Oct;83:171. doi: 10.1016/j.exger.2016.07.009. Epub 2016 Aug 4. No abstract available.

PMID:
27499524
13.

Prevalence of and factors associated with frailty and disability in older adults from China, Ghana, India, Mexico, Russia and South Africa.

Biritwum RB, Minicuci N, Yawson AE, Theou O, Mensah GP, Naidoo N, Wu F, Guo Y, Zheng Y, Jiang Y, Maximova T, Kalula S, Arokiasamy P, Salinas-Rodríguez A, Manrique-Espinoza B, Snodgrass JJ, Sterner KN, Eick G, Liebert MA, Schrock J, Afshar S, Thiele E, Vollmer S, Harttgen K, Strulik H, Byles JE, Rockwood K, Mitnitski A, Chatterji S, Kowal P; WHO SAGE Collaboration.

Maturitas. 2016 Sep;91:8-18. doi: 10.1016/j.maturitas.2016.05.012. Epub 2016 May 24.

PMID:
27451316
14.

Frailty and life satisfaction in Shanghai older adults: The roles of age and social vulnerability.

Yang F, Gu D, Mitnitski A.

Arch Gerontol Geriatr. 2016 Nov-Dec;67:68-73. doi: 10.1016/j.archger.2016.07.001. Epub 2016 Jul 12.

PMID:
27434744
15.

Changes in Frailty Predict Changes in Cognition in Older Men: The Honolulu-Asia Aging Study.

Armstrong JJ, Godin J, Launer LJ, White LR, Mitnitski A, Rockwood K, Andrew MK.

J Alzheimers Dis. 2016 Jun 15;53(3):1003-13. doi: 10.3233/JAD-151172.

16.

Heterogeneity of Human Aging and Its Assessment.

Mitnitski A, Howlett SE, Rockwood K.

J Gerontol A Biol Sci Med Sci. 2017 Jul 1;72(7):877-884. doi: 10.1093/gerona/glw089.

17.

Dynamical network model for age-related health deficits and mortality.

Taneja S, Mitnitski AB, Rockwood K, Rutenberg AD.

Phys Rev E. 2016 Feb;93(2):022309. doi: 10.1103/PhysRevE.93.022309. Epub 2016 Feb 29.

PMID:
26986354
18.

Mortality in Relation to Frailty in Patients Admitted to a Specialized Geriatric Intensive Care Unit.

Zeng A, Song X, Dong J, Mitnitski A, Liu J, Guo Z, Rockwood K.

J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1586-94. doi: 10.1093/gerona/glv084. Epub 2015 Sep 22.

19.

Frailty: Scaling from Cellular Deficit Accumulation?

Rockwood K, Mitnitski A, Howlett SE.

Interdiscip Top Gerontol Geriatr. 2015;41:1-14. doi: 10.1159/000381127. Epub 2015 Jul 17. Review.

PMID:
26301975
20.

Age-related frailty and its association with biological markers of ageing.

Mitnitski A, Collerton J, Martin-Ruiz C, Jagger C, von Zglinicki T, Rockwood K, Kirkwood TB.

BMC Med. 2015 Jul 13;13:161. doi: 10.1186/s12916-015-0400-x.

21.

Cumulative impact of health deficits, social vulnerabilities, and protective factors on cognitive dynamics in late life: a multistate modeling approach.

Armstrong JJ, Mitnitski A, Andrew MK, Launer LJ, White LR, Rockwood K.

Alzheimers Res Ther. 2015 Jun 5;7(1):38. doi: 10.1186/s13195-015-0120-7. eCollection 2015.

22.

The rate of aging: the rate of deficit accumulation does not change over the adult life span.

Mitnitski A, Rockwood K.

Biogerontology. 2016 Feb;17(1):199-204. doi: 10.1007/s10522-015-9583-y. Epub 2015 May 14.

PMID:
25972341
23.

A Frailty Index Based on Common Laboratory Tests in Comparison With a Clinical Frailty Index for Older Adults in Long-Term Care Facilities.

Rockwood K, McMillan M, Mitnitski A, Howlett SE.

J Am Med Dir Assoc. 2015 Oct 1;16(10):842-7. doi: 10.1016/j.jamda.2015.03.027. Epub 2015 May 5.

PMID:
25952475
24.

Derivation of a frailty index from the interRAI acute care instrument.

Hubbard RE, Peel NM, Samanta M, Gray LC, Fries BE, Mitnitski A, Rockwood K.

BMC Geriatr. 2015 Mar 18;15:27. doi: 10.1186/s12877-015-0026-z.

26.

What are frailty instruments for?

Rockwood K, Theou O, Mitnitski A.

Age Ageing. 2015 Jul;44(4):545-7. doi: 10.1093/ageing/afv043. Epub 2015 Mar 29. Review.

PMID:
25824236
27.

Social vulnerability and survival across levels of frailty in the Honolulu-Asia Aging Study.

Armstrong JJ, Andrew MK, Mitnitski A, Launer LJ, White LR, Rockwood K.

Age Ageing. 2015 Jul;44(4):709-12. doi: 10.1093/ageing/afv016. Epub 2015 Mar 10.

28.

Predicting 3-year survival in older people with intellectual disabilities using a Frailty Index.

Schoufour JD, Mitnitski A, Rockwood K, Evenhuis HM, Echteld MA.

J Am Geriatr Soc. 2015 Mar;63(3):531-6. doi: 10.1111/jgs.13239. Epub 2015 Mar 6.

PMID:
25754689
29.

The validation of a care partner-derived frailty index based upon comprehensive geriatric assessment (CP-FI-CGA) in emergency medical services and geriatric ambulatory care.

Goldstein J, Hubbard RE, Moorhouse P, Andrew MK, Mitnitski A, Rockwood K.

Age Ageing. 2015 Mar;44(2):327-30. doi: 10.1093/ageing/afu161. Epub 2014 Nov 1.

PMID:
25362501
30.

Age-related deficit accumulation and the risk of late-life dementia.

Song X, Mitnitski A, Rockwood K.

Alzheimers Res Ther. 2014 Sep 18;6(5-8):54. doi: 10.1186/s13195-014-0054-5. eCollection 2014.

31.

Aging as a process of deficit accumulation: its utility and origin.

Mitnitski A, Rockwood K.

Interdiscip Top Gerontol. 2015;40:85-98. doi: 10.1159/000364933. Epub 2014 Oct 13. Review.

32.

Standard laboratory tests to identify older adults at increased risk of death.

Howlett SE, Rockwood MR, Mitnitski A, Rockwood K.

BMC Med. 2014 Oct 7;12:171. doi: 10.1186/s12916-014-0171-9.

33.

Frailty in the Honolulu-Asia Aging Study: deficit accumulation in a male cohort followed to 90% mortality.

Armstrong JJ, Mitnitski A, Launer LJ, White LR, Rockwood K.

J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):125-31. doi: 10.1093/gerona/glu089. Epub 2014 Jun 27.

34.

Predicting disabilities in daily functioning in older people with intellectual disabilities using a frailty index.

Schoufour JD, Mitnitski A, Rockwood K, Hilgenkamp TI, Evenhuis HM, Echteld MA.

Res Dev Disabil. 2014 Oct;35(10):2267-77. doi: 10.1016/j.ridd.2014.05.022. Epub 2014 Jun 18.

PMID:
24950014
35.

Neuropsychiatric symptom clusters targeted for treatment at earlier versus later stages of dementia.

Rockwood K, Mitnitski A, Richard M, Kurth M, Kesslak P, Abushakra S.

Int J Geriatr Psychiatry. 2015 Apr;30(4):357-67. doi: 10.1002/gps.4136. Epub 2014 May 5.

PMID:
24798635
36.

Effect of health protective factors on health deficit accumulation and mortality risk in older adults in the Beijing Longitudinal Study of Aging.

Wang C, Song X, Mitnitski A, Fang X, Tang Z, Yu P, Rockwood K.

J Am Geriatr Soc. 2014 May;62(5):821-8. doi: 10.1111/jgs.12792. Epub 2014 Apr 18.

37.

Identifying common characteristics of frailty across seven scales.

Theou O, Brothers TD, Peña FG, Mitnitski A, Rockwood K.

J Am Geriatr Soc. 2014 May;62(5):901-6. doi: 10.1111/jgs.12773. Epub 2014 Apr 2.

PMID:
24697631
38.

Precipitating and predisposing events and symptoms for admission to assisted living or nursing home care.

Rockwood JKh, Richard M, Garden K, Hominick K, Mitnitski A, Rockwood K.

Can Geriatr J. 2013 Mar 5;17(1):16-21. doi: 10.5770/cgj.17.93. eCollection 2014 Mar.

39.

Comparison of alternate scoring of variables on the performance of the frailty index.

Peña FG, Theou O, Wallace L, Brothers TD, Gill TM, Gahbauer EA, Kirkland S, Mitnitski A, Rockwood K.

BMC Geriatr. 2014 Feb 24;14:25. doi: 10.1186/1471-2318-14-25.

40.

Characteristics of the least frail adults with intellectual disabilities: a positive biology perspective.

Schoufour JD, van Wijngaarden J, Mitnitski A, Rockwood K, Evenhuis HM, Echteld MA.

Res Dev Disabil. 2014 Jan;35(1):127-36. doi: 10.1016/j.ridd.2013.10.016. Epub 2013 Nov 16.

PMID:
24252590
41.

The risk of adverse outcomes in hospitalized older patients in relation to a frailty index based on a comprehensive geriatric assessment.

Evans SJ, Sayers M, Mitnitski A, Rockwood K.

Age Ageing. 2014 Jan;43(1):127-32. doi: 10.1093/ageing/aft156. Epub 2013 Oct 30.

PMID:
24171946
42.

Sex differences in the limit to deficit accumulation in late middle-aged and older Chinese people: results from the Beijing Longitudinal Study of Aging.

Shi J, Yang Z, Song X, Yu P, Fang X, Tang Z, Peng D, Mitnitski A, Rockwood K.

J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):702-9. doi: 10.1093/gerona/glt143. Epub 2013 Oct 14.

43.

Biological age revisited.

Mitnitski A, Rockwood K.

J Gerontol A Biol Sci Med Sci. 2014 Mar;69(3):295-6. doi: 10.1093/gerona/glt137. Epub 2013 Oct 10. No abstract available.

PMID:
24115774
44.

Operationalization of frailty using eight commonly used scales and comparison of their ability to predict all-cause mortality.

Theou O, Brothers TD, Mitnitski A, Rockwood K.

J Am Geriatr Soc. 2013 Sep;61(9):1537-51. doi: 10.1111/jgs.12420. Epub 2013 Aug 26.

PMID:
24028357
45.

Staging dementia from symptom profiles on a care partner website.

Rockwood K, Richard M, Leibman C, Mucha L, Mitnitski A.

J Med Internet Res. 2013 Aug 7;15(8):e145. doi: 10.2196/jmir.2461.

46.

Assessing biological aging: the origin of deficit accumulation.

Mitnitski A, Song X, Rockwood K.

Biogerontology. 2013 Dec;14(6):709-17. doi: 10.1007/s10522-013-9446-3. Epub 2013 Jul 17.

47.

Cognitive change in donepezil treated patients with vascular or mixed dementia.

Rockwood K, Mitnitski A, Black SE, Richard M, Defoy I, VASPECT study investigators.

Can J Neurol Sci. 2013 Jul;40(4):564-71.

PMID:
23786741
48.

Development of a frailty index for older people with intellectual disabilities: results from the HA-ID study.

Schoufour JD, Mitnitski A, Rockwood K, Evenhuis HM, Echteld MA.

Res Dev Disabil. 2013 May;34(5):1541-55. doi: 10.1016/j.ridd.2013.01.029. Epub 2013 Mar 5.

PMID:
23475005
49.

Co-occurrence of cardiometabolic diseases and frailty in older Chinese adults in the Beijing Longitudinal Study of Ageing.

Tang Z, Wang C, Song X, Shi J, Mitnitski A, Fang X, Yu P, Rockwood K.

Age Ageing. 2013 May;42(3):346-51. doi: 10.1093/ageing/aft004. Epub 2013 Mar 4. Erratum in: Age Ageing. 2013 Sep;42(5):663.

PMID:
23462693
50.

Exploring the relationship between national economic indicators and relative fitness and frailty in middle-aged and older Europeans.

Theou O, Brothers TD, Rockwood MR, Haardt D, Mitnitski A, Rockwood K.

Age Ageing. 2013 Sep;42(5):614-9. doi: 10.1093/ageing/aft010. Epub 2013 Feb 25.

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