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Items: 1 to 50 of 334

1.

Spatiotemporal immune zonation of the human kidney.

Stewart BJ, Ferdinand JR, Young MD, Mitchell TJ, Loudon KW, Riding AM, Richoz N, Frazer GL, Staniforth JUL, Vieira Braga FA, Botting RA, Popescu DM, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Polanski K, Efremova M, Green K, Del Castillo Velasco-Herrera M, Guzzo C, Collord G, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Lindsay S, Bajenoff M, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Behjati S, Clatworthy MR.

Science. 2019 Sep 27;365(6460):1461-1466. doi: 10.1126/science.aat5031.

PMID:
31604275
2.

Genomic landscape and chronological reconstruction of driver events in multiple myeloma.

Maura F, Bolli N, Angelopoulos N, Dawson KJ, Leongamornlert D, Martincorena I, Mitchell TJ, Fullam A, Gonzalez S, Szalat R, Abascal F, Rodriguez-Martin B, Samur MK, Glodzik D, Roncador M, Fulciniti M, Tai YT, Minvielle S, Magrangeas F, Moreau P, Corradini P, Anderson KC, Tubio JMC, Wedge DC, Gerstung M, Avet-Loiseau H, Munshi N, Campbell PJ.

Nat Commun. 2019 Aug 23;10(1):3835. doi: 10.1038/s41467-019-11680-1.

3.

Frequent and Persistent PLCG1 Mutations in Sézary Cells Directly Enhance PLCγ1 Activity and Stimulate NFκB, AP-1, and NFAT Signaling.

Patel VM, Flanagan CE, Martins M, Jones CL, Butler RM, Woollard WJ, Bakr FS, Yoxall A, Begum N, Katan M, Whittaker SJ, Mitchell TJ.

J Invest Dermatol. 2019 Jul 31. pii: S0022-202X(19)32679-X. doi: 10.1016/j.jid.2019.07.693. [Epub ahead of print]

PMID:
31376383
4.

Interactive molecular dynamics in virtual reality from quantum chemistry to drug binding: An open-source multi-person framework.

O'Connor MB, Bennie SJ, Deeks HM, Jamieson-Binnie A, Jones AJ, Shannon RJ, Walters R, Mitchell TJ, Mulholland AJ, Glowacki DR.

J Chem Phys. 2019 Jun 14;150(22):220901. doi: 10.1063/1.5092590.

PMID:
31202243
5.

Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia.

Hupp S, Grandgirard D, Mitchell TJ, Leib SL, Hathaway LJ, Iliev AI.

J Neuroinflammation. 2019 May 18;16(1):105. doi: 10.1186/s12974-019-1491-7.

6.

Characterization and validation of an intra-fraction motion management system for masked-based radiosurgery.

Knutson NC, Hawkins BJ, Bollinger D, Goddu SM, Kavanaugh JA, Santanam L, Mitchell TJ, Zoberi JE, Tsien C, Huang J, Robinson CG, Perkins SM, Dowling JL, Chicoine MR, Rich KM, Dunn GP, Mutic S.

J Appl Clin Med Phys. 2019 May;20(5):21-26. doi: 10.1002/acm2.12573. Epub 2019 May 4.

7.

Contribution of STAT3 and RAD23B in Primary Sézary Cells to Histone Deacetylase Inhibitor FK228 Resistance.

Butler RM, McKenzie RC, Jones CL, Flanagan CE, Woollard WJ, Demontis M, Ferreira S, Tosi I, John S, Whittaker SJ, Mitchell TJ.

J Invest Dermatol. 2019 Sep;139(9):1975-1984.e2. doi: 10.1016/j.jid.2019.03.1130. Epub 2019 Mar 22.

PMID:
30910759
8.

Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia.

Preston JA, Bewley MA, Marriott HM, McGarry Houghton A, Mohasin M, Jubrail J, Morris L, Stephenson YL, Cross S, Greaves DR, Craig RW, van Rooijen N, Bingle CD, Read RC, Mitchell TJ, Whyte MKB, Shapiro SD, Dockrell DH.

Am J Respir Crit Care Med. 2019 Jul 1;200(1):84-97. doi: 10.1164/rccm.201804-0646OC.

9.

Pilot study of head conformation changes over time in the Cavalier King Charles spaniel breed.

Knowler SP, Gillstedt L, Mitchell TJ, Jovanovik J, Volk HA, Rusbridge C.

Vet Rec. 2019 Jan 26;184(4):122. doi: 10.1136/vr.105135. Epub 2019 Jan 11.

10.

Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O.

Maurer J, Hupp S, Pillich H, Mitchell TJ, Chakraborty T, Iliev AI.

Sci Rep. 2018 Oct 26;8(1):15846. doi: 10.1038/s41598-018-34031-4.

11.

Host-Derived Microvesicles Carrying Bacterial Pore-Forming Toxins Deliver Signals to Macrophages: A Novel Mechanism of Shaping Immune Responses.

Köffel R, Wolfmeier H, Larpin Y, Besançon H, Schoenauer R, Babiychuk VS, Drücker P, Pabst T, Mitchell TJ, Babiychuk EB, Draeger A.

Front Immunol. 2018 Jul 27;9:1688. doi: 10.3389/fimmu.2018.01688. eCollection 2018.

12.

Genomics and clinical correlates of renal cell carcinoma.

Mitchell TJ, Rossi SH, Klatte T, Stewart GD.

World J Urol. 2018 Dec;36(12):1899-1911. doi: 10.1007/s00345-018-2429-x. Epub 2018 Aug 11. Review.

13.

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.

Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S.

Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699.

14.

IL-17 can be protective or deleterious in murine pneumococcal pneumonia.

Ritchie ND, Ritchie R, Bayes HK, Mitchell TJ, Evans TJ.

PLoS Pathog. 2018 May 29;14(5):e1007099. doi: 10.1371/journal.ppat.1007099. eCollection 2018 May.

15.

Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine.

Herbert JA, Kay EJ, Faustini SE, Richter A, Abouelhadid S, Cuccui J, Wren B, Mitchell TJ.

Vaccine. 2018 Jun 18;36(26):3809-3819. doi: 10.1016/j.vaccine.2018.05.036. Epub 2018 May 25.

16.

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Turajlic S, Xu H, Litchfield K, Rowan A, Horswell S, Chambers T, O'Brien T, Lopez JI, Watkins TBK, Nicol D, Stares M, Challacombe B, Hazell S, Chandra A, Mitchell TJ, Au L, Eichler-Jonsson C, Jabbar F, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Stewart A, Xing W, Smith JC, Escudero M, Huffman A, Matthews N, Elgar G, Phillimore B, Costa M, Begum S, Ward S, Salm M, Boeing S, Fisher R, Spain L, Navas C, Grönroos E, Hobor S, Sharma S, Aurangzeb I, Lall S, Polson A, Varia M, Horsfield C, Fotiadis N, Pickering L, Schwarz RF, Silva B, Herrero J, Luscombe NM, Jamal-Hanjani M, Rosenthal R, Birkbak NJ, Wilson GA, Pipek O, Ribli D, Krzystanek M, Csabai I, Szallasi Z, Gore M, McGranahan N, Van Loo P, Campbell P, Larkin J, Swanton C; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):595-610.e11. doi: 10.1016/j.cell.2018.03.043. Epub 2018 Apr 12.

17.

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

Mitchell TJ, Turajlic S, Rowan A, Nicol D, Farmery JHR, O'Brien T, Martincorena I, Tarpey P, Angelopoulos N, Yates LR, Butler AP, Raine K, Stewart GD, Challacombe B, Fernando A, Lopez JI, Hazell S, Chandra A, Chowdhury S, Rudman S, Soultati A, Stamp G, Fotiadis N, Pickering L, Au L, Spain L, Lynch J, Stares M, Teague J, Maura F, Wedge DC, Horswell S, Chambers T, Litchfield K, Xu H, Stewart A, Elaidi R, Oudard S, McGranahan N, Csabai I, Gore M, Futreal PA, Larkin J, Lynch AG, Szallasi Z, Swanton C, Campbell PJ; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):611-623.e17. doi: 10.1016/j.cell.2018.02.020. Epub 2018 Apr 12.

18.

Intra-tumour diversification in colorectal cancer at the single-cell level.

Roerink SF, Sasaki N, Lee-Six H, Young MD, Alexandrov LB, Behjati S, Mitchell TJ, Grossmann S, Lightfoot H, Egan DA, Pronk A, Smakman N, van Gorp J, Anderson E, Gamble SJ, Alder C, van de Wetering M, Campbell PJ, Stratton MR, Clevers H.

Nature. 2018 Apr;556(7702):457-462. doi: 10.1038/s41586-018-0024-3. Epub 2018 Apr 11.

PMID:
29643510
19.

Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia.

Gutbier B, Neuhauß AK, Reppe K, Ehrler C, Santel A, Kaufmann J, Scholz M, Weissmann N, Morawietz L, Mitchell TJ, Aliberti S, Hippenstiel S, Suttorp N, Witzenrath M; CAPNETZ and PROGRESS Study Groups ‡.

Am J Respir Crit Care Med. 2018 Jul 15;198(2):220-231. doi: 10.1164/rccm.201708-1733OC.

PMID:
29447449
20.

Expression of the lux genes in Streptococcus pneumoniae modulates pilus expression and virulence.

Herbert JA, Mitchell AM, Ritchie R, Ma J, Ross-Hutchinson K, Mitchell TJ.

PLoS One. 2018 Jan 17;13(1):e0189426. doi: 10.1371/journal.pone.0189426. eCollection 2018.

21.

Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge.

Morozov GI, Porat N, Kushnir T, Najmuldeen H, Adawi A, Chalifa-Caspi V, Benisty R, Ohayon A, Liron O, Azriel S, Malka I, Dotan S, Portnoi M, Piotrowski AA, Kafka D, Hajaj B, Fishilevich T, Shagan M, Tal M, Ellis R, Morrison DA, Mitchell AM, Mitchell TJ, Dagan R, Yesilkaya H, Nebenzahl YM.

Sci Rep. 2018 Jan 10;8(1):314. doi: 10.1038/s41598-017-18645-8.

22.

Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.

Nerlich A, Mieth M, Letsiou E, Fatykhova D, Zscheppang K, Imai-Matsushima A, Meyer TF, Paasch L, Mitchell TJ, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Eggeling S, Schimek M, Witzenrath M, Suttorp N, Hippenstiel S, Hocke AC.

Sci Rep. 2018 Jan 9;8(1):182. doi: 10.1038/s41598-017-18468-7.

23.

Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2.

Gutbier B, Schönrock SM, Ehrler C, Haberberger R, Dietert K, Gruber AD, Kummer W, Michalick L, Kuebler WM, Hocke AC, Szymanski K, Letsiou E, Lüth A, Schumacher F, Kleuser B, Mitchell TJ, Bertrams W, Schmeck B, Treue D, Klauschen F, Bauer TT, Tönnies M, Weissmann N, Hippenstiel S, Suttorp N, Witzenrath M; CAPNETZ Study Group.

Crit Care Med. 2018 Mar;46(3):e258-e267. doi: 10.1097/CCM.0000000000002916.

PMID:
29298188
24.

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia.

Gutbier B, Jiang X, Dietert K, Ehrler C, Lienau J, Van Slyke P, Kim H, Hoang VC, Maynes JT, Dumont DJ, Gruber AD, Weissmann N, Mitchell TJ, Suttorp N, Witzenrath M.

Crit Care. 2017 Nov 13;21(1):274. doi: 10.1186/s13054-017-1851-6.

25.

Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation.

Hupp S, Ribes S, Seele J, Bischoff C, Förtsch C, Maier E, Benz R, Mitchell TJ, Nau R, Iliev AI.

Br J Pharmacol. 2017 Dec;174(23):4295-4307. doi: 10.1111/bph.14027. Epub 2017 Oct 19.

26.

Streptococcus pneumoniae and lytic antibiotic therapy: are we adding insult to injury during invasive pneumococcal disease and sepsis?

Brown LA, Mitchell AM, Mitchell TJ.

J Med Microbiol. 2017 Aug 10. doi: 10.1099/jmm.0.000545. [Epub ahead of print]

PMID:
28792379
27.

Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties.

Lizcano A, Akula Suresh Babu R, Shenoy AT, Saville AM, Kumar N, D'Mello A, Hinojosa CA, Gilley RP, Segovia J, Mitchell TJ, Tettelin H, Orihuela CJ.

Microbes Infect. 2017 Jun;19(6):323-333. doi: 10.1016/j.micinf.2017.04.001. Epub 2017 Apr 10.

28.

Pneumolysin mediates heterotypic aggregation of neutrophils and platelets in vitro.

Nel JG, Durandt C, Theron AJ, Tintinger GR, Pool R, Richards GA, Mitchell TJ, Feldman C, Anderson R.

J Infect. 2017 Jun;74(6):599-608. doi: 10.1016/j.jinf.2017.02.010. Epub 2017 Mar 4.

PMID:
28267572
29.

Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes.

Maurer J, Hupp S, Bischoff C, Foertsch C, Mitchell TJ, Chakraborty T, Iliev AI.

Toxins (Basel). 2017 Jan 13;9(1). pii: E34. doi: 10.3390/toxins9010034.

30.

Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack.

Wolfmeier H, Radecke J, Schoenauer R, Koeffel R, Babiychuk VS, Drücker P, Hathaway LJ, Mitchell TJ, Zuber B, Draeger A, Babiychuk EB.

Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2498-2509. doi: 10.1016/j.bbagen.2016.07.022. Epub 2016 Jul 30.

PMID:
27481675
31.

NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence.

Kostadinova E, Chaput C, Gutbier B, Lippmann J, Sander LE, Mitchell TJ, Suttorp N, Witzenrath M, Opitz B.

Sci Rep. 2016 Aug 1;6:30943. doi: 10.1038/srep30943.

32.

Pneumolysin Mediates Platelet Activation In Vitro.

Nel JG, Durandt C, Mitchell TJ, Feldman C, Anderson R, Tintinger GR.

Lung. 2016 Aug;194(4):589-93. doi: 10.1007/s00408-016-9900-5. Epub 2016 May 18.

PMID:
27192991
33.

Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome.

Woollard WJ, Pullabhatla V, Lorenc A, Patel VM, Butler RM, Bayega A, Begum N, Bakr F, Dedhia K, Fisher J, Aguilar-Duran S, Flanagan C, Ghasemi AA, Hoffmann RM, Castillo-Mosquera N, Nuttall EA, Paul A, Roberts CA, Solomonidis EG, Tarrant R, Yoxall A, Beyers CZ, Ferreira S, Tosi I, Simpson MA, de Rinaldis E, Mitchell TJ, Whittaker SJ.

Blood. 2016 Jun 30;127(26):3387-97. doi: 10.1182/blood-2016-02-699843. Epub 2016 Apr 27.

PMID:
27121473
34.

Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine.

Mizrachi Nebenzahl Y, Blau K, Kushnir T, Shagan M, Portnoi M, Cohen A, Azriel S, Malka I, Adawi A, Kafka D, Dotan S, Guterman G, Troib S, Fishilevich T, Gershoni JM, Braiman A, Mitchell AM, Mitchell TJ, Porat N, Goliand I, Chalifa Caspi V, Swiatlo E, Tal M, Ellis R, Elia N, Dagan R.

PLoS One. 2016 Mar 18;11(3):e0150320. doi: 10.1371/journal.pone.0150320. eCollection 2016.

35.

Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES.

Bokori-Brown M, Petrov PG, Khafaji MA, Mughal MK, Naylor CE, Shore AC, Gooding KM, Casanova F, Mitchell TJ, Titball RW, Winlove CP.

J Biol Chem. 2016 May 6;291(19):10210-27. doi: 10.1074/jbc.M115.691899. Epub 2016 Mar 16.

36.

Evaluation of Immunophenotypic and Molecular Biomarkers for Sézary Syndrome Using Standard Operating Procedures: A Multicenter Study of 59 Patients.

Boonk SE, Zoutman WH, Marie-Cardine A, van der Fits L, Out-Luiting JJ, Mitchell TJ, Tosi I, Morris SL, Moriarty B, Booken N, Felcht M, Quaglino P, Ponti R, Barberio E, Ram-Wolff C, Jäntti K, Ranki A, Bernengo MG, Klemke CD, Bensussan A, Michel L, Whittaker S, Bagot M, Tensen CP, Willemze R, Vermeer MH.

J Invest Dermatol. 2016 Jul;136(7):1364-1372. doi: 10.1016/j.jid.2016.01.038. Epub 2016 Feb 28.

37.

Independent Loss of Methylthioadenosine Phosphorylase (MTAP) in Primary Cutaneous T-Cell Lymphoma.

Woollard WJ, Kalaivani NP, Jones CL, Roper C, Tung L, Lee JJ, Thomas BR, Tosi I, Ferreira S, Beyers CZ, McKenzie RCT, Butler RM, Lorenc A, Whittaker SJ, Mitchell TJ.

J Invest Dermatol. 2016 Jun;136(6):1238-1246. doi: 10.1016/j.jid.2016.01.028. Epub 2016 Feb 9.

38.

Resting-State Blood Oxygen Level-Dependent Functional MRI: A Paradigm Shift in Preoperative Brain Mapping.

Leuthardt EC, Allen M, Kamran M, Hawasli AH, Snyder AZ, Hacker CD, Mitchell TJ, Shimony JS.

Stereotact Funct Neurosurg. 2015;93(6):427-39. doi: 10.1159/000442424. Epub 2016 Jan 20. Review.

39.

Pneumolysin activates neutrophil extracellular trap formation.

Nel JG, Theron AJ, Durandt C, Tintinger GR, Pool R, Mitchell TJ, Feldman C, Anderson R.

Clin Exp Immunol. 2016 Jun;184(3):358-67. doi: 10.1111/cei.12766. Epub 2016 Mar 2.

40.

Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets.

Hitchcock JR, Cook CN, Bobat S, Ross EA, Flores-Langarica A, Lowe KL, Khan M, Dominguez-Medina CC, Lax S, Carvalho-Gaspar M, Hubscher S, Rainger GE, Cobbold M, Buckley CD, Mitchell TJ, Mitchell A, Jones ND, Van Rooijen N, Kirchhofer D, Henderson IR, Adams DH, Watson SP, Cunningham AF.

J Clin Invest. 2015 Dec;125(12):4429-46. doi: 10.1172/JCI79070. Epub 2015 Nov 16.

41.

Immune ageing and susceptibility to Streptococcus pneumoniae.

Gonçalves MT, Mitchell TJ, Lord JM.

Biogerontology. 2016 Jun;17(3):449-65. doi: 10.1007/s10522-015-9614-8. Epub 2015 Oct 15. Review.

PMID:
26472172
42.

Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue.

Fatykhova D, Rabes A, Machnik C, Guruprasad K, Pache F, Berg J, Toennies M, Bauer TT, Schneider P, Schimek M, Eggeling S, Mitchell TJ, Mitchell AM, Hilker R, Hain T, Suttorp N, Hippenstiel S, Hocke AC, Opitz B.

PLoS One. 2015 Aug 28;10(8):e0137108. doi: 10.1371/journal.pone.0137108. eCollection 2015.

43.

A Serine-Threonine Kinase (StkP) Regulates Expression of the Pneumococcal Pilus and Modulates Bacterial Adherence to Human Epithelial and Endothelial Cells In Vitro.

Herbert JA, Mitchell AM, Mitchell TJ.

PLoS One. 2015 Jun 19;10(6):e0127212. doi: 10.1371/journal.pone.0127212. eCollection 2015.

44.

Genetic conjugation of components in two pneumococcal fusion protein vaccines enhances paediatric mucosal immune responses.

Pope C, Oliver EH, Ma J, Langton Hewer C, Mitchell TJ, Finn A.

Vaccine. 2015 Mar 30;33(14):1711-8. doi: 10.1016/j.vaccine.2015.02.012. Epub 2015 Feb 17.

PMID:
25698489
45.

Normative amplitude-integrated EEG measures in preterm infants.

Vesoulis ZA, Paul RA, Mitchell TJ, Wong C, Inder TE, Mathur AM.

J Perinatol. 2015 Jun;35(6):428-33. doi: 10.1038/jp.2014.225. Epub 2014 Dec 18.

46.

Seroprevalence and risk factors associated with exposure of water buffalo (Bubalus bubalis) to Neospora caninum in northeast Thailand.

Kengradomkij C, Inpankaew T, Kamyingkird K, Wongpanit K, Wongnakphet S, Mitchell TJ, Xuan X, Igarashi I, Jittapalapong S, Stich RW.

Vet Parasitol. 2015 Jan 15;207(1-2):156-60. doi: 10.1016/j.vetpar.2014.10.034. Epub 2014 Nov 27.

PMID:
25499824
47.

Resting-state blood oxygen level-dependent functional magnetic resonance imaging for presurgical planning.

Kamran M, Hacker CD, Allen MG, Mitchell TJ, Leuthardt EC, Snyder AZ, Shimony JS.

Neuroimaging Clin N Am. 2014 Nov;24(4):655-69. doi: 10.1016/j.nic.2014.07.009. Epub 2014 Sep 6. Review.

48.

Quantitative high dynamic range beam profiling for fluorescence microscopy.

Mitchell TJ, Saunter CD, O'Nions W, Girkin JM, Love GD.

Rev Sci Instrum. 2014 Oct;85(10):103713. doi: 10.1063/1.4899208.

PMID:
25362409
49.

Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation.

Bewley MA, Naughton M, Preston J, Mitchell A, Holmes A, Marriott HM, Read RC, Mitchell TJ, Whyte MK, Dockrell DH.

MBio. 2014 Oct 7;5(5):e01710-14. doi: 10.1128/mBio.01710-14.

50.

Exposure of a 23F serotype strain of Streptococcus pneumoniae to cigarette smoke condensate is associated with selective upregulation of genes encoding the two-component regulatory system 11 (TCS11).

Cockeran R, Herbert JA, Mitchell TJ, Dix-Peek T, Dickens C, Anderson R, Feldman C.

Biomed Res Int. 2014;2014:976347. doi: 10.1155/2014/976347. Epub 2014 Jun 11.

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