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Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors.

Dalvi S, Nguyen HH, On N, Mitchell RW, Aukema HM, Miller DW, Hatch GM.

J Neurochem. 2015 Dec;135(5):867-79. doi: 10.1111/jnc.13117. Epub 2015 Apr 27.


Role of dystrophin in airway smooth muscle phenotype, contraction and lung function.

Sharma P, Basu S, Mitchell RW, Stelmack GL, Anderson JE, Halayko AJ.

PLoS One. 2014 Jul 23;9(7):e102737. doi: 10.1371/journal.pone.0102737. eCollection 2014.


Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation.

Taylor WA, Mejia EM, Mitchell RW, Choy PC, Sparagna GC, Hatch GM.

PLoS One. 2012;7(11):e48628. doi: 10.1371/journal.pone.0048628. Epub 2012 Nov 9.


Epithelium-dependent modulation of responsiveness of airways from caveolin-1 knockout mice is mediated through cyclooxygenase-2 and 5-lipoxygenase.

Sharma P, Ryu MH, Basu S, Maltby SA, Yeganeh B, Mutawe MM, Mitchell RW, Halayko AJ.

Br J Pharmacol. 2012 Oct;167(3):548-60. doi: 10.1111/j.1476-5381.2012.02014.x.


Delineating the role of alterations in lipid metabolism to the pathogenesis of inherited skeletal and cardiac muscle disorders: Thematic Review Series: Genetics of Human Lipid Diseases.

Saini-Chohan HK, Mitchell RW, Vaz FM, Zelinski T, Hatch GM.

J Lipid Res. 2012 Jan;53(1):4-27. doi: 10.1194/jlr.R012120. Epub 2011 Nov 7. Review.


Fatty acid transport into the brain: of fatty acid fables and lipid tails.

Mitchell RW, Hatch GM.

Prostaglandins Leukot Essent Fatty Acids. 2011 Nov;85(5):293-302. doi: 10.1016/j.plefa.2011.04.007. Epub 2011 Aug 3. Review.


Mifepristone treatment results in differential regulation of glycerolipid biosynthesis in baby hamster kidney cells expressing a mifepristone-inducible ABCA1.

Hauff KD, Mitchell RW, Xu FY, Dembinski T, Mymin D, Zha X, Choy PC, Hatch GM.

Lipids. 2011 Sep;46(9):795-804. doi: 10.1007/s11745-011-3582-9. Epub 2011 Jun 28.


Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells.

Mitchell RW, On NH, Del Bigio MR, Miller DW, Hatch GM.

J Neurochem. 2011 May;117(4):735-46. doi: 10.1111/j.1471-4159.2011.07245.x. Epub 2011 Mar 31.


A resolution between mentalism and teleonomy, or fodder for a continuing dialogue?

Mitchell RW.

Integr Psychol Behav Sci. 2010 Dec;44(4):360-9. doi: 10.1007/s12124-010-9140-9.


MEK modulates force-fluctuation-induced relengthening of canine tracheal smooth muscle.

Dowell ML, Lavoie TL, Lakser OJ, Dulin NO, Fredberg JJ, Gerthoffer WT, Seow CY, Mitchell RW, Solway J.

Eur Respir J. 2010 Sep;36(3):630-7. doi: 10.1183/09031936.00160209. Epub 2010 Jan 28.


Characterization of microRNAs encoded by the bovine herpesvirus 1 genome.

Glazov EA, Horwood PF, Assavalapsakul W, Kongsuwan K, Mitchell RW, Mitter N, Mahony TJ.

J Gen Virol. 2010 Jan;91(Pt 1):32-41. doi: 10.1099/vir.0.014290-0. Epub 2009 Sep 30.


Regulation of cardiolipin biosynthesis by fatty acid transport protein-1 IN HEK 293 cells.

Mitchell RW, Hatch GM.

Biochim Biophys Acta. 2009 Oct;1788(10):2015-21. doi: 10.1016/j.bbamem.2009.06.002. Epub 2009 Jun 11.


On the mechanism of oleate transport across human brain microvessel endothelial cells.

Mitchell RW, Edmundson CL, Miller DW, Hatch GM.

J Neurochem. 2009 Aug;110(3):1049-57. doi: 10.1111/j.1471-4159.2009.06199.x. Epub 2009 May 31.


Disrupting actin-myosin-actin connectivity in airway smooth muscle as a treatment for asthma?

Lavoie TL, Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Seow CY, Mitchell RW, Solway J.

Proc Am Thorac Soc. 2009 May 1;6(3):295-300. doi: 10.1513/pats.200808-078RM. Review.


Self-awareness without inner speech: a commentary on Morin.

Mitchell RW.

Conscious Cogn. 2009 Jun;18(2):532-4. doi: 10.1016/j.concog.2008.12.003. Epub 2009 Jan 17.


Steroids augment relengthening of contracted airway smooth muscle: potential additional mechanism of benefit in asthma.

Lakser OJ, Dowell ML, Hoyte FL, Chen B, Lavoie TL, Ferreira C, Pinto LH, Dulin NO, Kogut P, Churchill J, Mitchell RW, Solway J.

Eur Respir J. 2008 Nov;32(5):1224-30. doi: 10.1183/09031936.00092908. Epub 2008 Sep 3.


Gene-environment interactions in a mutant mouse kindred with native airway constrictor hyperresponsiveness.

Pinto LH, Eaton E, Chen B, Fleisher J, Shuster D, McCauley J, Kedainis D, Siepka SM, Shimomura K, Song EJ, Husain A, Lakser OJ, Mitchell RW, Dowell ML, Brown M, Camoretti-Mercado B, Naclerio R, Sperling AI, Levin SI, Turek FW, Solway J.

Mamm Genome. 2008 Jan;19(1):2-14. doi: 10.1007/s00335-007-9082-9. Epub 2008 Jan 1.


Force fluctuation-induced relengthening of acetylcholine-contracted airway smooth muscle.

Mitchell RW, Dowell ML, Solway J, Lakser OJ.

Proc Am Thorac Soc. 2008 Jan 1;5(1):68-72. Review.


Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.

An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L.

Eur Respir J. 2007 May;29(5):834-60. Review.


Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits.

Dupasquier CM, Weber AM, Ander BP, Rampersad PP, Steigerwald S, Wigle JT, Mitchell RW, Kroeger EA, Gilchrist JS, Moghadasian MM, Lukas A, Pierce GN.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2987-96. Epub 2006 Jul 14.


Tidal breathing pattern differentially antagonizes bronchoconstriction in C57BL/6J vs. A/J mice.

Chen B, Liu G, Shardonofsky F, Dowell M, Lakser O, Mitchell RW, Fredberg JJ, Pinto LH, Solway J.

J Appl Physiol (1985). 2006 Jul;101(1):249-55. Epub 2006 Feb 16.


On the terminology for describing the length-force relationship and its changes in airway smooth muscle.

Bai TR, Bates JH, Brusasco V, Camoretti-Mercado B, Chitano P, Deng LH, Dowell M, Fabry B, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gunst SJ, Hai CM, Halayko AJ, Hirst SJ, James AL, Janssen LJ, Jones KA, King GG, Lakser OJ, Lambert RK, Lauzon AM, Lutchen KR, Maksym GN, Meiss RA, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Schellenberg RR, Seow CY, Sieck GC, Smith PG, Smolensky AV, Solway J, Stephens NL, Stewart AG, Tang DD, Wang L.

J Appl Physiol (1985). 2004 Dec;97(6):2029-34. Review.


Latrunculin B increases force fluctuation-induced relengthening of ACh-contracted, isotonically shortened canine tracheal smooth muscle.

Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Stelmack GL, Halayko AJ, Solway J, Mitchell RW.

J Appl Physiol (1985). 2005 Feb;98(2):489-97. Epub 2004 Oct 1.


Methodologic advancements in the study of airway smooth muscle.

Kotlikoff MI, Kannan MS, Solway J, Deng KY, Deshpande DA, Dowell M, Feldman M, Green KS, Ji G, Johnston R, Lakser O, Lee J, Lund FE, Milla C, Mitchell RW, Nakai J, Rishniw M, Walseth TF, White TA, Wilson J, Xin HB, Woodruff PG.

J Allergy Clin Immunol. 2004 Aug;114(2 Suppl):S18-31. Review.


Force and myosin light chain phosphorylation in dog airway smooth muscle activated in different ways.

Burdyga T, Mitchell RW, Ragozzino J, Ford LE.

Respir Physiol Neurobiol. 2003 Sep 16;137(2-3):141-9.


Do inflammatory mediators influence the contribution of airway smooth muscle contraction to airway hyperresponsiveness in asthma?

Fernandes DJ, Mitchell RW, Lakser O, Dowell M, Stewart AG, Solway J.

J Appl Physiol (1985). 2003 Aug;95(2):844-53. Review.


The RhoA/Rho kinase pathway regulates nuclear localization of serum response factor.

Liu HW, Halayko AJ, Fernandes DJ, Harmon GS, McCauley JA, Kocieniewski P, McConville J, Fu Y, Forsythe SM, Kogut P, Bellam S, Dowell M, Churchill J, Lesso H, Kassiri K, Mitchell RW, Hershenson MB, Camoretti-Mercado B, Solway J.

Am J Respir Cell Mol Biol. 2003 Jul;29(1):39-47. Epub 2003 Jan 10.


Myosin light chain phosphorylation facilitates in vivo myosin filament reassembly after mechanical perturbation.

Qi D, Mitchell RW, Burdyga T, Ford LE, Kuo KH, Seow CY.

Am J Physiol Cell Physiol. 2002 Jun;282(6):C1298-305.


Relationship between myosin phosphorylation and contractile capability of canine airway smooth muscle.

Mitchell RW, Seow CY, Burdyga T, Maass-Moreno R, Pratusevich VR, Ragozzino J, Ford LE.

J Appl Physiol (1985). 2001 Jun;90(6):2460-5.


Simple freezing apparatus for resolving rapid metabolic events associated with smooth muscle activation.

Maass-Moreno R, Burdyga T, Mitchell RW, Seow CY, Ragozzino J, Ford LE.

J Appl Physiol (1985). 2001 Jun;90(6):2453-9.


Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes.

Mitchell RW, Halayko AJ, Kahraman S, Solway J, Wylam ME.

Am J Physiol Lung Cell Mol Physiol. 2000 May;278(5):L1091-100.


Macaques but not lemurs co-orient visually with humans.

Anderson JR, Mitchell RW.

Folia Primatol (Basel). 1999 Jan-Feb;70(1):17-22.


Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes.

Halayko AJ, Camoretti-Mercado B, Forsythe SM, Vieira JE, Mitchell RW, Wylam ME, Hershenson MB, Solway J.

Am J Physiol. 1999 Jan;276(1):L197-206. doi: 10.1152/ajplung.1999.276.1.L197.


Eosinophils, major basic protein, and polycationic peptides augment bovine airway myocyte Ca2+ mobilization.

Wylam ME, Gungor N, Mitchell RW, Umans JG.

Am J Physiol. 1998 Jun;274(6):L997-L1005. doi: 10.1152/ajplung.1998.274.6.L997.


Differential effects of cyclosporine A after acute antigen challenge in sensitized cats in vivo and ex vivo.

Mitchell RW, Cozzi P, Ndukwu IM, Spaethe S, Leff AR, Padrid PA.

Br J Pharmacol. 1998 Mar;123(6):1198-204.


Pointing, withholding information, and deception in capuchin monkeys (Cebus apella).

Mitchell RW, Anderson JR.

J Comp Psychol. 1997 Dec;111(4):351-61.


Passive sensitization of human airways induces myogenic contractile responses in vitro.

Mitchell RW, Rabe KF, Magnussen H, Leff AR.

J Appl Physiol (1985). 1997 Oct;83(4):1276-81.


EP1 receptor blockade attenuates both spontaneous tone and PGE2-elicited contraction in guinea pig trachealis.

Ndukwu IM, White SR, Leff AR, Mitchell RW.

Am J Physiol. 1997 Sep;273(3 Pt 1):L626-33.


A comparison of the self-awareness and kinesthetic-visual matching theories of self-recognition: autistic children and others.

Mitchell RW.

Ann N Y Acad Sci. 1997 Jun 18;818:38-62. Review. No abstract available.


Muscarinic hyperresponsiveness of antigen-sensitized feline airway smooth muscle in vitro.

Mitchell RW, Ndukwu IM, Leff AR, Padrid PA.

Am J Vet Res. 1997 Jun;58(6):672-6.


Conservation of bronchiolar wall area during constriction and dilation of human airways.

Mitchell RW, Rühlmann E, Magnussen H, Muñoz NM, Leff AR, Rabe KF.

J Appl Physiol (1985). 1997 Mar;82(3):954-8.


Differential tachykinin receptor subtype activation in capsaicin and KCl contractions of guinea pig trachealis.

Mitchell RW, Ndukwu IM, Herrnreiter A, Uzendoski K, Gitter B, Solway J, Leff AR.

Am J Physiol. 1995 Dec;269(6 Pt 1):L837-42.


Evidence of dolphin self-recognition and the difficulties of interpretation.

Mitchell RW.

Conscious Cogn. 1995 Jun;4(2):229-34. No abstract available.


Cyproheptadine-induced attenuation of type-I immediate-hypersensitivity reactions of airway smooth muscle from immune-sensitized cats.

Padrid PA, Mitchell RW, Ndukwu IM, Spaethe S, Shiue P, Cozzi P, Leff AR, Shiou P [corrected to Shiue P].

Am J Vet Res. 1995 Jan;56(1):109-15. Erratum in: Am J Vet Res 1995 Mar;56(3):402.


Passive sensitization of human bronchi augments smooth muscle shortening velocity and capacity.

Mitchell RW, Rühlmann E, Magnussen H, Leff AR, Rabe KF.

Am J Physiol. 1994 Aug;267(2 Pt 1):L218-22.


Immune sensitization augments epithelium-dependent spontaneous tone in guinea pig trachealis.

Ndukwu IM, Solway J, Arbetter K, Uzendoski K, Leff AR, Mitchell RW.

Am J Physiol. 1994 May;266(5 Pt 1):L485-92.


Exposure of immature rats to hyperoxia increases tracheal smooth muscle stress generation in vitro.

Hershenson MB, Wylam ME, Punjabi N, Umans JG, Schumacker PT, Mitchell RW, Solway J.

J Appl Physiol (1985). 1994 Feb;76(2):743-9.


Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis.

Mitchell RW, Ndukwu IM, Arbetter K, Solway J, Leff AR.

Am J Physiol. 1993 Dec;265(6 Pt 1):L549-54.


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