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Growth and Resorption of Chronic Subdural Hematomas: Gardner, Weir, and the Osmotic Hypothesis Revisited.

Thomas PAW, Marshman LAG, Rudd D, Moffat C, Mitchell PS.

World Neurosurg. 2019 Dec;132:e202-e207. doi: 10.1016/j.wneu.2019.08.204. Epub 2019 Sep 4.


Prospective randomized placebo-controlled double-blind clinical study of adjuvant dexamethasone with surgery for chronic subdural haematoma with post-operative subdural drainage: Interim analysis.

Mebberson K, Colditz M, Marshman LAG, Thomas PAW, Mitchell PS, Robertson K.

J Clin Neurosci. 2019 Sep 3. pii: S0967-5868(19)31364-5. doi: 10.1016/j.jocn.2019.08.095. [Epub ahead of print]


The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries.

Mitchell PS, Sandstrom A, Vance RE.

Curr Opin Immunol. 2019 Oct;60:37-45. doi: 10.1016/j.coi.2019.04.015. Epub 2019 May 20. Review.


Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes.

Sandstrom A, Mitchell PS, Goers L, Mu EW, Lesser CF, Vance RE.

Science. 2019 Apr 5;364(6435). pii: eaau1330. doi: 10.1126/science.aau1330. Epub 2019 Mar 14.


Utility of the Abbott RealTime HCV Genotype Plus RUO assay used in combination with the Abbott RealTime HCV Genotype II assay.

He C, Germer JJ, Ptacek ER, Bommersbach CE, Mitchell PS, Yao JDC.

J Clin Virol. 2018 Feb - Mar;99-100:97-100. doi: 10.1016/j.jcv.2018.01.004. Epub 2018 Jan 12.


An Assessment of Host Associations, Geographic Distributions, and Genetic Diversity of Avian Chewing Lice (Insecta: Phthiraptera) from Benin.

Takano OM, Mitchell PS, Gustafsson DR, Adite A, Voelker G, Light JE.

J Parasitol. 2017 Apr;103(2):152-160. doi: 10.1645/16-137. Epub 2017 Jan 7.


The cobas® 6800/8800 System: a new era of automation in molecular diagnostics.

Cobb B, Simon CO, Stramer SL, Body B, Mitchell PS, Reisch N, Stevens W, Carmona S, Katz L, Will S, Liesenfeld O.

Expert Rev Mol Diagn. 2017 Feb;17(2):167-180. doi: 10.1080/14737159.2017.1275962. Review.


Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation.

Chavarría-Smith J, Mitchell PS, Ho AM, Daugherty MD, Vance RE.

PLoS Pathog. 2016 Dec 7;12(12):e1006052. doi: 10.1371/journal.ppat.1006052. eCollection 2016 Dec.


Outcome of microsurgical excision of unruptured brain arteriovenous malformations in ARUBA-eligible patients.

Javadpour M, Al-Mahfoudh R, Mitchell PS, Kirollos R.

Br J Neurosurg. 2016 Dec;30(6):619-622. Epub 2016 May 13.


Management of Giant Calcified Thoracic Disks and Description of the Trench Vertebrectomy Technique.

Al-Mahfoudh R, Mitchell PS, Wilby M, Crooks D, Barrett C, Pillay R, Pigott T.

Global Spine J. 2016 Sep;6(6):584-91. doi: 10.1055/s-0035-1570087. Epub 2015 Dec 19.


Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction.

Mitchell PS, Young JM, Emerman M, Malik HS.

PLoS Pathog. 2015 Dec 10;11(12):e1005304. doi: 10.1371/journal.ppat.1005304. eCollection 2015 Dec.


The development of an efficient mass balance approach for the purity assignment of organic calibration standards.

Davies SR, Alamgir M, Chan BK, Dang T, Jones K, Krishnaswami M, Luo Y, Mitchell PS, Moawad M, Swan H, Tarrant GJ.

Anal Bioanal Chem. 2015 Oct;407(26):7983-93. doi: 10.1007/s00216-015-8971-0. Epub 2015 Sep 5.


Purity assessment of organic calibration standards using a combination of quantitative NMR and mass balance.

Davies SR, Jones K, Goldys A, Alamgir M, Chan BK, Elgindy C, Mitchell PS, Tarrant GJ, Krishnaswami MR, Luo Y, Moawad M, Lawes D, Hook JM.

Anal Bioanal Chem. 2015 Apr;407(11):3103-13. doi: 10.1007/s00216-014-7893-6. Epub 2014 Jun 20.


Adoption of lean principles in a high-volume molecular diagnostic microbiology laboratory.

Mitchell PS, Mandrekar JN, Yao JD.

J Clin Microbiol. 2014 Jul;52(7):2689-93. doi: 10.1128/JCM.00430-14. Epub 2014 May 14.


Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity.

Huang JW, Wang Y, Dhillon KK, Calses P, Villegas E, Mitchell PS, Tewari M, Kemp CJ, Taniguchi T.

Mol Cancer Res. 2013 Dec;11(12):1564-73. doi: 10.1158/1541-7786.MCR-13-0292. Epub 2013 Oct 2.


Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia.

Cheng HH, Mitchell PS, Kroh EM, Dowell AE, Chéry L, Siddiqui J, Nelson PS, Vessella RL, Knudsen BS, Chinnaiyan AM, Pienta KJ, Morrissey C, Tewari M.

PLoS One. 2013 Jul 30;8(7):e69239. doi: 10.1371/journal.pone.0069239. Print 2013.


An evolutionary perspective on the broad antiviral specificity of MxA.

Mitchell PS, Emerman M, Malik HS.

Curr Opin Microbiol. 2013 Aug;16(4):493-9. doi: 10.1016/j.mib.2013.04.005. Epub 2013 May 28. Review.


Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA.

Mitchell PS, Patzina C, Emerman M, Haller O, Malik HS, Kochs G.

Cell Host Microbe. 2012 Oct 18;12(4):598-604. doi: 10.1016/j.chom.2012.09.005.


MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression.

Wang Y, Huang JW, Li M, Cavenee WK, Mitchell PS, Zhou X, Tewari M, Furnari FB, Taniguchi T.

Mol Cancer Res. 2011 Aug;9(8):1100-11. doi: 10.1158/1541-7786.MCR-11-0007. Epub 2011 Jun 21.


Hepatitis C virus genotypes in clinical specimens tested at a national reference testing laboratory in the United States.

Germer JJ, Mandrekar JN, Bendel JL, Mitchell PS, Yao JD.

J Clin Microbiol. 2011 Aug;49(8):3040-3. doi: 10.1128/JCM.00457-11. Epub 2011 May 25.


Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma.

Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, Mitchell PS, Bennett CF, Pogosova-Agadjanyan EL, Stirewalt DL, Tait JF, Tewari M.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5003-8. doi: 10.1073/pnas.1019055108. Epub 2011 Mar 7.


MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B, CDKNIC and overall survival.

Wurz K, Garcia RL, Goff BA, Mitchell PS, Lee JH, Tewari M, Swisher EM.

Genes Chromosomes Cancer. 2010 Jul;49(7):577-84. doi: 10.1002/gcc.20768.


Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR).

Kroh EM, Parkin RK, Mitchell PS, Tewari M.

Methods. 2010 Apr;50(4):298-301. doi: 10.1016/j.ymeth.2010.01.032. Epub 2010 Feb 8. Erratum in: Methods. 2010 Nov;52(3):268.


Anomalous quantitation standard growth curves in a laboratory-developed hepatitis C virus (HCV) RNA quantification assay using the TaqMan HCV analyte-specific reagent.

Germer JJ, Kathrotiya JD, Bouse CF, Mitchell PS, Yao JD.

J Clin Microbiol. 2009 Jul;47(7):2317-20. doi: 10.1128/JCM.00028-09. Epub 2009 May 6.


Multiple integrated copies and high-level production of the human retrovirus XMRV (xenotropic murine leukemia virus-related virus) from 22Rv1 prostate carcinoma cells.

Knouf EC, Metzger MJ, Mitchell PS, Arroyo JD, Chevillet JR, Tewari M, Miller AD.

J Virol. 2009 Jul;83(14):7353-6. doi: 10.1128/JVI.00546-09. Epub 2009 Apr 29.


Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries.

Wyman SK, Parkin RK, Mitchell PS, Fritz BR, O'Briant K, Godwin AK, Urban N, Drescher CW, Knudsen BS, Tewari M.

PLoS One. 2009;4(4):e5311. doi: 10.1371/journal.pone.0005311. Epub 2009 Apr 23.


Comparison of the Abbott realtime human immunodeficiency virus type 1 (HIV-1) assay to the Cobas AmpliPrep/Cobas TaqMan HIV-1 test: workflow, reliability, and direct costs.

Sloma CR, Germer JJ, Gerads TM, Mandrekar JN, Mitchell PS, Yao JD.

J Clin Microbiol. 2009 Apr;47(4):889-95. doi: 10.1128/JCM.02231-08. Epub 2009 Feb 4.


An FTIR investigation of flanking sequence effects on the structure and flexibility of DNA binding sites.

Kahn TR, Fong KK, Jordan B, Lek JC, Levitan R, Mitchell PS, Wood C, Hatcher ME.

Biochemistry. 2009 Feb 17;48(6):1315-21. doi: 10.1021/bi8015235.


Circulating microRNAs as stable blood-based markers for cancer detection.

Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O'Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari M.

Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10513-8. doi: 10.1073/pnas.0804549105. Epub 2008 Jul 28.


MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries.

Bar M, Wyman SK, Fritz BR, Qi J, Garg KS, Parkin RK, Kroh EM, Bendoraite A, Mitchell PS, Nelson AM, Ruzzo WL, Ware C, Radich JP, Gentleman R, Ruohola-Baker H, Tewari M.

Stem Cells. 2008 Oct;26(10):2496-505. doi: 10.1634/stemcells.2008-0356. Epub 2008 Jun 26.


Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer.

Grady WM, Parkin RK, Mitchell PS, Lee JH, Kim YH, Tsuchiya KD, Washington MK, Paraskeva C, Willson JK, Kaz AM, Kroh EM, Allen A, Fritz BR, Markowitz SD, Tewari M.

Oncogene. 2008 Jun 19;27(27):3880-8. doi: 10.1038/onc.2008.10. Epub 2008 Feb 11.


Impact of the COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, Version 1.5, on clinical laboratory operations.

Germer JJ, Bendel JL, Dolenc CA, Nelson SR, Masters AL, Gerads TM, Mandrekar JN, Mitchell PS, Yao JD.

J Clin Microbiol. 2007 Sep;45(9):3101-4. Epub 2007 Jul 18.


Detection of HIV-1 proviral DNA with the AMPLICOR HIV-1 DNA Test, version 1.5, following sample processing by the MagNA Pure LC instrument.

Germer JJ, Gerads TM, Mandrekar JN, Mitchell PS, Yao JD.

J Clin Virol. 2006 Nov;37(3):195-8. Epub 2006 Sep 12.


Evaluation of the invader assay for genotyping hepatitis C virus.

Germer JJ, Majewski DW, Yung B, Mitchell PS, Yao JD.

J Clin Microbiol. 2006 Feb;44(2):318-23.


Evaluation of the MagNA Pure LC used with the TRUGENE HBV Genotyping Kit.

Gintowt AA, Germer JJ, Mitchell PS, Yao JD.

J Clin Virol. 2005 Oct;34(2):155-7.


Evaluation of the COBAS TaqMan HCV test with automated sample processing using the MagNA pure LC instrument.

Germer JJ, Harmsen WS, Mandrekar JN, Mitchell PS, Yao JD.

J Clin Microbiol. 2005 Jan;43(1):293-8.


Automated sample preparation for the TRUGENE HIV-1 genotyping kit using the MagNA pure LC instrument.

Germer JJ, Vandenameele JN, Mitchell PS, Harmsen WS, Yao JD.

Diagn Microbiol Infect Dis. 2004 May;49(1):59-61.


Clinical spectrum and laboratory characteristics associated with detection of herpes simplex virus DNA in cerebrospinal fluid.

O'Sullivan CE, Aksamit AJ, Harrington JR, Harmsen WS, Mitchell PS, Patel R.

Mayo Clin Proc. 2003 Nov;78(11):1347-52.


Evaluation of the TRUGENE HCV 5'NC genotyping kit with the new GeneLibrarian module 3.1.2 for genotyping of hepatitis C virus from clinical specimens.

Germer JJ, Majewski DW, Rosser M, Thompson A, Mitchell PS, Smith TF, Elagin S, Yao JD.

J Clin Microbiol. 2003 Oct;41(10):4855-7. Erratum in: J Clin Microbiol. 2004 Aug;42(8):3911.


Evaluation of the MagNA pure LC instrument for extraction of hepatitis C virus RNA for the COBAS AMPLICOR Hepatitis C Virus Test, version 2.0.

Germer JJ, Lins MM, Jensen ME, Harmsen WS, Ilstrup DM, Mitchell PS, Cockerill FR 3rd, Patel R.

J Clin Microbiol. 2003 Aug;41(8):3503-8.


Minimal exposure to ethanol increases ethanol preference in Maudsley reactive male rats.

Adams N, Campbell SD, Mitchell PS.

Alcohol. 2003 Apr;29(3):149-56.


A simple PDMS-based electro-fluidic interface for microchip electrophoretic separations.

Sanders JC, Breadmore MC, Mitchell PS, Landers JP.

Analyst. 2002 Dec;127(12):1558-63.


Ethanol self-administration in Maudsley reactive and Maudsley nonreactive inbred rats.

Adams N, Mitchell PS, Campbell SD, Samson HH.

Alcohol. 2002 Apr;26(3):155-61.


Synthesis of pyrroloquinolines as indole analogues of flavonols.

Black DS, Kumar N, Mitchell PS.

J Org Chem. 2002 Apr 19;67(8):2464-73.


Comparison of line probe assay and DNA sequencing of 5' untranslated region for genotyping hepatitis C virus: description of novel line probe patterns.

Mitchell PS, Sloan LM, Majewski DW, Rys PN, Heimgartner PJ, Rosenblatt JE, Cockerill FR 3rd, Smith TF, Patel R.

Diagn Microbiol Infect Dis. 2002 Mar;42(3):175-9.


Multiplex LightCycler PCR assay for detection and differentiation of Bordetella pertussis and Bordetella parapertussis in nasopharyngeal specimens.

Sloan LM, Hopkins MK, Mitchell PS, Vetter EA, Rosenblatt JE, Harmsen WS, Cockerill FR, Patel R.

J Clin Microbiol. 2002 Jan;40(1):96-100.


Diagnosis of herpes simplex virus infections in the clinical laboratory by LightCycler PCR.

Espy MJ, Uhl JR, Mitchell PS, Thorvilson JN, Svien KA, Wold AD, Smith TF.

J Clin Microbiol. 2000 Feb;38(2):795-9.


Analysis of candidate-host immunogenetic determinants in herpes simplex virus-associated Mollaret's meningitis.

Tang YW, Cleavinger PJ, Li H, Mitchell PS, Smith TF, Persing DH.

Clin Infect Dis. 2000 Jan;30(1):176-8.


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