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Urinary Excretion Profile of 11-Nor-9-Carboxy-Δ9-Tetrahydrocannabinol (THCCOOH) Following Smoked and Vaporized Cannabis Administration in Infrequent Cannabis Users.

Spindle TR, Cone EJ, Schlienz NJ, Mitchell JM, Bigelow GE, Flegel R, Hayes E, Vandrey R.

J Anal Toxicol. 2019 May 16. pii: bkz038. doi: 10.1093/jat/bkz038. [Epub ahead of print]


New methods to identify high peak density artifacts in Fourier transform mass spectra and to mitigate their effects on high-throughput metabolomic data analysis.

Mitchell JM, Flight RM, Wang QJ, Higashi RM, Fan TW, Lane AN, Moseley HNB.

Metabolomics. 2018 Sep 17;14(10):125. doi: 10.1007/s11306-018-1426-9.


Acute Effects of Smoked and Vaporized Cannabis in Healthy Adults Who Infrequently Use Cannabis: A Crossover Trial.

Spindle TR, Cone EJ, Schlienz NJ, Mitchell JM, Bigelow GE, Flegel R, Hayes E, Vandrey R.

JAMA Netw Open. 2018 Nov 2;1(7):e184841. doi: 10.1001/jamanetworkopen.2018.4841. Erratum in: JAMA Netw Open. 2018 Dec 7;1(8):e187241.


Acute Pharmacokinetic Profile of Smoked and Vaporized Cannabis in Human Blood and Oral Fluid.

Spindle TR, Cone EJ, Schlienz NJ, Mitchell JM, Bigelow GE, Flegel R, Hayes E, Vandrey R.

J Anal Toxicol. 2019 May 1;43(4):233-258. doi: 10.1093/jat/bky104.


Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche.

Sosa E, Chen D, Rojas EJ, Hennebold JD, Peters KA, Wu Z, Lam TN, Mitchell JM, Sukhwani M, Tailor RC, Meistrich ML, Orwig KE, Shetty G, Clark AT.

Nat Commun. 2018 Dec 17;9(1):5339. doi: 10.1038/s41467-018-07740-7.


Comparison of dynamic contrast-enhanced magnetic resonance imaging and contrast-enhanced ultrasound for evaluation of the effects of sorafenib in a rat model of hepatocellular carcinoma.

Muñoz NM, Minhaj AA, Maldonado KL, Kingsley CV, Cortes AC, Taghavi H, Polak U, Mitchell JM, Ensor JE, Bankson JA, Rashid A, Avritscher R.

Magn Reson Imaging. 2019 Apr;57:156-164. doi: 10.1016/j.mri.2018.11.012. Epub 2018 Nov 19.


Donor spermatogenesis in de novo formed seminiferous tubules from transplanted testicular cells in rhesus monkey testis.

Shetty G, Mitchell JM, Lam TNA, Wu Z, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Orwig KE, Meistrich ML.

Hum Reprod. 2018 Dec 1;33(12):2249-2255. doi: 10.1093/humrep/dey316.


System for Scoring Severity of Acute Radiation Syndrome Response in Rhesus Macaques (Macaca mulatta).

King GL, Sandgren DJ, Mitchell JM, Bolduc DL, Blakely WF.

Comp Med. 2018 Dec 1;68(6):474-488. doi: 10.30802/AALAS-CM-17-000106. Epub 2018 Oct 10.


Dopamine, time perception, and future time perspective.

Mitchell JM, Weinstein D, Vega T, Kayser AS.

Psychopharmacology (Berl). 2018 Oct;235(10):2783-2793. doi: 10.1007/s00213-018-4971-z. Epub 2018 Jul 19.


A potentially important role for T cells and regulatory T cells in Langerhans cell histiocytosis.

Mitchell JM, Berzins SP, Kannourakis G.

Clin Immunol. 2018 Sep;194:19-25. doi: 10.1016/j.clim.2018.06.004. Epub 2018 Jun 18. Review.


Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution.

Miller PW, Pokutta S, Mitchell JM, Chodaparambil JV, Clarke DN, Nelson WJ, Weis WI, Nichols SA.

J Biol Chem. 2018 Jul 27;293(30):11674-11686. doi: 10.1074/jbc.RA117.001325. Epub 2018 Jun 7.


NKX2.2, PDX-1 and CDX-2 as potential biomarkers to differentiate well-differentiated neuroendocrine tumors.

Yang MX, Coates RF, Ambaye A, Cortright V, Mitchell JM, Buskey AM, Zubarik R, Liu JG, Ades S, Barry MM.

Biomark Res. 2018 Apr 18;6:15. doi: 10.1186/s40364-018-0129-8. eCollection 2018.


Development and application of two multiplex real-time PCR assays for detection and speciation of bacterial pathogens in the koala.

Hulse LS, Hickey D, Mitchell JM, Beagley KW, Ellis W, Johnston SD.

J Vet Diagn Invest. 2018 Jul;30(4):523-529. doi: 10.1177/1040638718770490. Epub 2018 Apr 9.


An update in international trends in incidence rates of thyroid cancer, 1973-2007.

James BC, Mitchell JM, Jeon HD, Vasilottos N, Grogan RH, Aschebrook-Kilfoy B.

Cancer Causes Control. 2018 May;29(4-5):465-473. doi: 10.1007/s10552-018-1023-2. Epub 2018 Apr 5.


First live birth after uterus transplantation in the United States.

Testa G, McKenna GJ, Gunby RT Jr, Anthony T, Koon EC, Warren AM, Putman JM, Zhang L, dePrisco G, Mitchell JM, Wallis K, Klintmalm GB, Olausson M, Johannesson L.

Am J Transplant. 2018 May;18(5):1270-1274. doi: 10.1111/ajt.14737. Epub 2018 Apr 12.


Development of a Quantitative LC-MS-MS Assay for Codeine, Morphine, 6-Acetylmorphine, Hydrocodone, Hydromorphone, Oxycodone and Oxymorphone in Neat Oral Fluid.

Grabenauer M, Moore KN, Bynum ND, White RM, Mitchell JM, Hayes ED, Flegel R.

J Anal Toxicol. 2018 Jul 1;42(6):392-399. doi: 10.1093/jat/bky021.


Pharmacokinetic Characterization of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in Urine Following Acute Oral Cannabis Ingestion in Healthy Adults.

Schlienz NJ, Cone EJ, Herrmann ES, Lembeck NA, Mitchell JM, Bigelow GE, Flegel R, LoDico CP, Hayes ED, Vandrey R.

J Anal Toxicol. 2018 May 1;42(4):232-247. doi: 10.1093/jat/bkx102.


Treatments and Health Outcomes of Medicare Patients With Back Pain.

Mitchell JM, Hadley J.

Med Care Res Rev. 2018 Jan 1:1077558717751209. doi: 10.1177/1077558717751209. [Epub ahead of print]


Assessment of the stability of DNA in specimens collected under conditions for drug testing-A pilot study.

White RM Sr, Mitchell JM, Hart ED, Evans A, Meaders M, Norsworthy SE, Hayes ED, Flegel R, Maha GC, Shaffer MD, Hall EM, Rogers K.

Forensic Sci Int. 2018 Feb;283:41-46. doi: 10.1016/j.forsciint.2017.11.011. Epub 2017 Nov 13.


Detection and quantification of codeine-6-glucuronide, hydromorphone-3-glucuronide, oxymorphone-3-glucuronide, morphine 3-glucuronide and morphine-6-glucuronide in human hair from opioid users by LC-MS-MS.

Grabenauer M, Bynum ND, Moore KN, White RM, Mitchell JM, Hayes ED, Flegel R.

J Anal Toxicol. 2018 Mar 1;42(2):115-125. doi: 10.1093/jat/bkx086.


Specialization as an Organizing Principle: The Case of Ambulatory Surgery Centers.

Carey K, Mitchell JM.

Med Care Res Rev. 2017 Aug 1:1077558717729228. doi: 10.1177/1077558717729228. [Epub ahead of print]


Specialization and production cost efficiency: evidence from ambulatory surgery centers.

Carey K, Mitchell JM.

Int J Health Econ Manag. 2018 Mar;18(1):83-98. doi: 10.1007/s10754-017-9225-9. Epub 2017 Sep 12.


Significance of positive and inhibitory regulators in the TGF-β signaling pathway in colorectal cancers.

Coates RF, Gardner JA, Gao Y, Cortright VM, Mitchell JM, Ashikaga T, Skelly J, Yang MX.

Hum Pathol. 2017 Aug;66:34-39. doi: 10.1016/j.humpath.2017.05.021. Epub 2017 Jun 7.


Examining Drivers of Health Care Spending: Evidence on Self-referral Among a Privately Insured Population.

Mitchell JM, Reschovsky JD, Film RJ, Franzini L.

Med Care. 2017 Jul;55(7):684-692. doi: 10.1097/MLR.0000000000000732.


Living Donor Uterus Transplantation: A Single Center's Observations and Lessons Learned From Early Setbacks to Technical Success.

Testa G, Koon EC, Johannesson L, McKenna GJ, Anthony T, Klintmalm GB, Gunby RT, Warren AM, Putman JM, dePrisco G, Mitchell JM, Wallis K, Olausson M.

Am J Transplant. 2017 Nov;17(11):2901-2910. doi: 10.1111/ajt.14326. Epub 2017 May 23.


Pharmacokinetic Profile of Oral Cannabis in Humans: Blood and Oral Fluid Disposition and Relation to Pharmacodynamic Outcomes.

Vandrey R, Herrmann ES, Mitchell JM, Bigelow GE, Flegel R, LoDico C, Cone EJ.

J Anal Toxicol. 2017 Mar 1;41(2):83-99. doi: 10.1093/jat/bkx012.


Right inferior frontal cortex activity correlates with tolcapone responsivity in problem and pathological gamblers.

Kayser AS, Vega T, Weinstein D, Peters J, Mitchell JM.

Neuroimage Clin. 2016 Dec 20;13:339-348. doi: 10.1016/j.nicl.2016.12.022. eCollection 2017.


Exploring the potential of boronic acids as inhibitors of OXA-24/40 β-lactamase.

Werner JP, Mitchell JM, Taracila MA, Bonomo RA, Powers RA.

Protein Sci. 2017 Mar;26(3):515-526. doi: 10.1002/pro.3100. Epub 2017 Feb 23.


Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.

Plisson F, Hill TA, Mitchell JM, Hoang HN, de Araujo AD, Xu W, Cotterell A, Edmonds DJ, Stanton RV, Derksen DR, Loria PM, Griffith DA, Price DA, Liras S, Fairlie DP.

Eur J Med Chem. 2017 Feb 15;127:703-714. doi: 10.1016/j.ejmech.2016.10.044. Epub 2016 Oct 21.


Implementation of a structured programme of preceptorship for newly qualified midwives in a maternity unit.

Mitchell JM, Davies S.

Nurs Manag (Harrow). 2016 Sep 30;23(6):35-39.


Prescription Opioids. V. Metabolism and Excretion of Oxymorphone in Urine Following Controlled Single Dose Administration.

DePriest AZ, Heltsley R, Black DL, Mitchell JM, LoDico C, Flegel R, Cone EJ.

J Anal Toxicol. 2016 Oct;40(8):566-574. Epub 2016 Jul 11.


Prescription Opioids. VI. Metabolism and Excretion of Hydromorphone in Urine Following Controlled Single-Dose Administration.

DePriest AZ, Heltsley R, Black DL, Mitchell JM, LoDico C, Flegel R, Cone EJ.

J Anal Toxicol. 2016 Oct;40(8):575-582. Epub 2016 Jul 11.


Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV Exposures.

Srinivasan P, Moss JA, Gunawardana M, Churchman SA, Yang F, Dinh CT, Mitchell JM, Zhang J, Fanter R, Miller CS, Butkyavichene I, McNicholl JM, Smith TJ, Baum MM, Smith JM.

PLoS One. 2016 Jun 8;11(6):e0157061. doi: 10.1371/journal.pone.0157061. eCollection 2016.


Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.

Swedberg JE, Schroeder CI, Mitchell JM, Fairlie DP, Edmonds DJ, Griffith DA, Ruggeri RB, Derksen DR, Loria PM, Price DA, Liras S, Craik DJ.

J Biol Chem. 2016 Jul 22;291(30):15778-87. doi: 10.1074/jbc.M116.724542. Epub 2016 May 10.


Intranasal Oxytocin Selectively Modulates Social Perception, Craving, and Approach Behavior in Subjects With Alcohol Use Disorder.

Mitchell JM, Arcuni PA, Weinstein D, Woolley JD.

J Addict Med. 2016 May-Jun;10(3):182-9. doi: 10.1097/ADM.0000000000000213.


Use of Physical Therapy Following Total Knee Replacement Surgery: Implications of Orthopedic Surgeons' Ownership of Physical Therapy Services.

Mitchell JM, Reschovsky JD, Reicherter EA.

Health Serv Res. 2016 Oct;51(5):1838-57. doi: 10.1111/1475-6773.12465. Epub 2016 Feb 23.


A Comparison of Ambulatory Surgery Center Production Costs and Medicare Payments: Evidence on Colonoscopy and Endoscopy.

Mitchell JM, Carey K.

Med Care. 2016 Feb;54(2):126-32. doi: 10.1097/MLR.0000000000000466.


The effect of maternal and child early life factors on grade repetition among HIV exposed and unexposed children in rural KwaZulu-Natal, South Africa.

Mitchell JM, Rochat TJ, Houle B, Stein A, Newell ML, Bland RM.

J Dev Orig Health Dis. 2016 Apr;7(2):185-96. doi: 10.1017/S2040174415007230. Epub 2015 Oct 9. Erratum in: J Dev Orig Health Dis. 2016 Apr;7(2):218.


Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists.

Swedberg JE, Schroeder CI, Mitchell JM, Durek T, Fairlie DP, Edmonds DJ, Griffith DA, Ruggeri RB, Derksen DR, Loria PM, Liras S, Price DA, Craik DJ.

Eur J Med Chem. 2015 Oct 20;103:175-84. doi: 10.1016/j.ejmech.2015.08.046. Epub 2015 Aug 29.


Nonsmoker Exposure to Secondhand Cannabis Smoke. III. Oral Fluid and Blood Drug Concentrations and Corresponding Subjective Effects.

Cone EJ, Bigelow GE, Herrmann ES, Mitchell JM, LoDico C, Flegel R, Vandrey R.

J Anal Toxicol. 2015 Sep;39(7):497-509. doi: 10.1093/jat/bkv070. Epub 2015 Jul 2.


Molecular and histologic considerations in the assessment of serrated polyps.

Yang HM, Mitchell JM, Sepulveda JL, Sepulveda AR.

Arch Pathol Lab Med. 2015 Jun;139(6):730-41. doi: 10.5858/arpa.2014-0424-RA. Review.


Prescription Opioids. IV: Disposition of Hydrocodone in Oral Fluid and Blood Following Single-Dose Administration.

Cone EJ, DePriest AZ, Heltsley R, Black DL, Mitchell JM, LoDico C, Flegel R.

J Anal Toxicol. 2015 Sep;39(7):510-8. doi: 10.1093/jat/bkv050. Epub 2015 May 10.


Non-smoker exposure to secondhand cannabis smoke II: Effect of room ventilation on the physiological, subjective, and behavioral/cognitive effects.

Herrmann ES, Cone EJ, Mitchell JM, Bigelow GE, LoDico C, Flegel R, Vandrey R.

Drug Alcohol Depend. 2015 Jun 1;151:194-202. doi: 10.1016/j.drugalcdep.2015.03.019. Epub 2015 Apr 6.


Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.

Hoang HN, Song K, Hill TA, Derksen DR, Edmonds DJ, Kok WM, Limberakis C, Liras S, Loria PM, Mascitti V, Mathiowetz AM, Mitchell JM, Piotrowski DW, Price DA, Stanton RV, Suen JY, Withka JM, Griffith DA, Fairlie DP.

J Med Chem. 2015 May 14;58(9):4080-5. doi: 10.1021/acs.jmedchem.5b00166. Epub 2015 Apr 16.


Structural basis of activity against aztreonam and extended spectrum cephalosporins for two carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii.

Mitchell JM, Clasman JR, June CM, Kaitany KC, LaFleur JR, Taracila MA, Klinger NV, Bonomo RA, Wymore T, Szarecka A, Powers RA, Leonard DA.

Biochemistry. 2015 Mar 17;54(10):1976-87. doi: 10.1021/bi501547k. Epub 2015 Mar 2.


Response to protocol review scenario: submit a new proposal.

Mitchell JM, Wafer LN.

Lab Anim (NY). 2015 Feb;44(2):57-8. doi: 10.1038/laban.689. No abstract available.


Prescription opioids. III. Disposition of oxycodone in oral fluid and blood following controlled single-dose administration.

Cone EJ, DePriest AZ, Heltsley R, Black DL, Mitchell JM, LoDico C, Flegel R.

J Anal Toxicol. 2015 Apr;39(3):192-202. doi: 10.1093/jat/bku176. Epub 2015 Jan 13.


Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease.

Wilkerson I, Laban J, Mitchell JM, Sheibani N, Alcendor DJ.

J Neuroinflammation. 2015 Jan 9;12:2. doi: 10.1186/s12974-014-0219-y.


Chemotherapy with cytochalasin congeners in vitro and in vivo against murine models.

Trendowski M, Mitchell JM, Corsette CM, Acquafondata C, Fondy TP.

Invest New Drugs. 2015 Apr;33(2):290-9. doi: 10.1007/s10637-014-0203-5. Epub 2015 Jan 7.


Chemotherapy in vivo against M109 murine lung carcinoma with cytochalasin B by localized, systemic, and liposomal administration.

Trendowski M, Mitchell JM, Corsette CM, Acquafondata C, Fondy TP.

Invest New Drugs. 2015 Apr;33(2):280-9. doi: 10.1007/s10637-014-0202-6. Epub 2015 Jan 6.

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