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Bioactive glass-containing hydrogel delivery system for osteogenic differentiation of human dental pulp stem cells.

Sevari SP, Shahnazi S, Chen C, Mitchell JC, Ansari S, Moshaverinia A.

J Biomed Mater Res A. 2019 Nov 9. doi: 10.1002/jbm.a.36836. [Epub ahead of print]


Myristic Acid Coated Protein Immobilised Mesoporous Silica Particles as pH Induced Oral Delivery System for the Delivery of Biomolecules.

Trivedi V, Bhomia R, Mitchell JC.

Pharmaceuticals (Basel). 2019 Oct 12;12(4). pii: E153. doi: 10.3390/ph12040153.


Using Small-Angle Scattering Data and Parametric Machine Learning to Optimize Force Field Parameters for Intrinsically Disordered Proteins.

Demerdash O, Shrestha UR, Petridis L, Smith JC, Mitchell JC, Ramanathan A.

Front Mol Biosci. 2019 Aug 13;6:64. doi: 10.3389/fmolb.2019.00064. eCollection 2019.


Predicting kinase inhibitors using bioactivity matrix derived informer sets.

Zhang H, Ericksen SS, Lee CP, Ananiev GE, Wlodarchak N, Yu P, Mitchell JC, Gitter A, Wright SJ, Hoffmann FM, Wildman SA, Newton MA.

PLoS Comput Biol. 2019 Aug 5;15(8):e1006813. doi: 10.1371/journal.pcbi.1006813. eCollection 2019 Aug.


Development and evaluation of performance characteristics of timolol-loaded composite ocular films as potential delivery platforms for treatment of glaucoma.

Tighsazzadeh M, Mitchell JC, Boateng JS.

Int J Pharm. 2019 Jul 20;566:111-125. doi: 10.1016/j.ijpharm.2019.05.059. Epub 2019 May 23.


Prediction of human intestinal absorption using micellar liquid chromatography with an aminopropyl stationary phase.

Shokry DS, Waters LJ, Parkes GMB, Mitchell JC.

Biomed Chromatogr. 2019 Jul;33(7):e4515. doi: 10.1002/bmc.4515. Epub 2019 Mar 20.


Review: Modelling the pathology and behaviour of frontotemporal dementia.

Solomon DA, Mitchell JC, Salcher-Konrad MT, Vance CA, Mizielinska S.

Neuropathol Appl Neurobiol. 2019 Feb;45(1):58-80. doi: 10.1111/nan.12536. Review.


Formation of a Bile Salt-Drug Hydrogel to Predict Human Intestinal Absorption.

Shokry DS, Waters LJ, Parkes GMB, Mitchell JC, Snowden MJ.

J Pharm Sci. 2019 Jan;108(1):279-287. doi: 10.1016/j.xphs.2018.10.005. Epub 2018 Oct 12.


Rapid identification of nonblood sterile site broth cultures using the FilmArray blood culture identification panel.

Messacar K, Hamilton SL, Prinzi AM, Mitchell JC, Beil ED, Dowell EB, Dominguez SR.

Diagn Microbiol Infect Dis. 2019 Jan;93(1):22-23. doi: 10.1016/j.diagmicrobio.2018.07.018. Epub 2018 Jul 31.


Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption.

Shokry DS, Waters LJ, Parkes GMB, Mitchell JC.

Biomed Chromatogr. 2018 Dec;32(12):e4351. doi: 10.1002/bmc.4351. Epub 2018 Aug 16.


The development of a novel smart material based on colloidal microgels and cotton.

Majcen N, Mohsen R, Snowden MJ, Mitchell JC, Voncina B.

Adv Colloid Interface Sci. 2018 Jun;256:193-202. doi: 10.1016/j.cis.2018.04.005. Epub 2018 Apr 22.


dbAMEPNI: a database of alanine mutagenic effects for protein-nucleic acid interactions.

Liu L, Xiong Y, Gao H, Wei DQ, Mitchell JC, Zhu X.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay034.


Effect of plasma surface treatment of poly(dimethylsiloxane) on the permeation of pharmaceutical compounds.

Waters LJ, Finch CV, Bhuiyan AKMMH, Hemming K, Mitchell JC.

J Pharm Anal. 2017 Oct;7(5):338-342. doi: 10.1016/j.jpha.2017.05.003. Epub 2017 May 19.


Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice.

So E, Mitchell JC, Memmi C, Chennell G, Vizcay-Barrena G, Allison L, Shaw CE, Vance C.

Hum Mol Genet. 2018 Feb 1;27(3):463-474. doi: 10.1093/hmg/ddx415.


Effects of crystal habit on the sticking propensity of ibuprofen-A case study.

Hooper D, Clarke FC, Docherty R, Mitchell JC, Snowden MJ.

Int J Pharm. 2017 Oct 5;531(1):266-275. doi: 10.1016/j.ijpharm.2017.08.091. Epub 2017 Aug 24.


Preparation of polycaprolactone nanoparticles via supercritical carbon dioxide extraction of emulsions.

Ajiboye AL, Trivedi V, Mitchell JC.

Drug Deliv Transl Res. 2018 Dec;8(6):1790-1796. doi: 10.1007/s13346-017-0422-3.


Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Smith BN, Topp SD, Fallini C, Shibata H, Chen HJ, Troakes C, King A, Ticozzi N, Kenna KP, Soragia-Gkazi A, Miller JW, Sato A, Dias DM, Jeon M, Vance C, Wong CH, de Majo M, Kattuah W, Mitchell JC, Scotter EL, Parkin NW, Sapp PC, Nolan M, Nestor PJ, Simpson M, Weale M, Lek M, Baas F, Vianney de Jong JM, Ten Asbroek ALMA, Redondo AG, Esteban-Pérez J, Tiloca C, Verde F, Duga S, Leigh N, Pall H, Morrison KE, Al-Chalabi A, Shaw PJ, Kirby J, Turner MR, Talbot K, Hardiman O, Glass JD, De Belleroche J, Maki M, Moss SE, Miller C, Gellera C, Ratti A, Al-Sarraj S, Brown RH Jr, Silani V, Landers JE, Shaw CE.

Sci Transl Med. 2017 May 3;9(388). pii: eaad9157. doi: 10.1126/scitranslmed.aad9157.


Maladaptive Cardiac Autonomic Control during a Stress Reactivity Assessment Among Primary Care Patients with Metabolic Syndrome.

Mitchell JC, Paulson J, Cannarozzi M, Neer SM, Cassisi JE.

Appl Psychophysiol Biofeedback. 2017 Jun;42(2):97-105. doi: 10.1007/s10484-017-9355-3.


The Use of Bile Salt Micelles for the Prediction of Human Intestinal Absorption.

Waters LJ, Shokry DS, Parkes GMB, Mitchell JC.

J Pharm Sci. 2016 Dec;105(12):3611-3614. doi: 10.1016/j.xphs.2016.09.007. Epub 2016 Oct 21.


The thermal and storage stability of bovine haemoglobin by ultraviolet-visible and circular dichroism spectroscopies.

Bhomia R, Trivedi V, Coleman NJ, Mitchell JC.

J Pharm Anal. 2016 Aug;6(4):242-248. doi: 10.1016/j.jpha.2016.02.004. Epub 2016 Mar 8.


ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.

Stoica R, Paillusson S, Gomez-Suaga P, Mitchell JC, Lau DH, Gray EH, Sancho RM, Vizcay-Barrena G, De Vos KJ, Shaw CE, Hanger DP, Noble W, Miller CC.

EMBO Rep. 2016 Sep;17(9):1326-42. doi: 10.15252/embr.201541726. Epub 2016 Jul 14.


A Mouthful of Anomalies.

Adamji R, Bryant C, Ahluwalia M, Mitchell JC.

Dent Update. 2016 Jul-Aug;43(6):545-8.


Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate.

Bondulich MK, Guo T, Meehan C, Manion J, Rodriguez Martin T, Mitchell JC, Hortobagyi T, Yankova N, Stygelbout V, Brion JP, Noble W, Hanger DP.

Brain. 2016 Aug;139(Pt 8):2290-306. doi: 10.1093/brain/aww137. Epub 2016 Jun 12.


DBSI server: DNA binding site identifier.

Sukumar S, Zhu X, Ericksen SS, Mitchell JC.

Bioinformatics. 2016 Sep 15;32(18):2853-5. doi: 10.1093/bioinformatics/btw315. Epub 2016 Jun 3.


Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy.

Ehiwe TO, Alexander BD, Mitchell JC, Snowden MJ, Waters LJ.

J Pharm Anal. 2016 Jun;6(3):179-183. doi: 10.1016/j.jpha.2015.12.002. Epub 2016 Jan 8.


Evaluating the privacy properties of telephone metadata.

Mayer J, Mutchler P, Mitchell JC.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5536-41. doi: 10.1073/pnas.1508081113.


Modeling Sexual Assault Risk Perception Among Heterosexual College Females: The Impact of Previous Victimization, Alcohol Use, and Coping Style.

Mitchell JC, MacLeod BP, Cassisi JE.

Violence Against Women. 2017 Feb;23(2):143-162. doi: 10.1177/1077801216638767. Epub 2016 Jul 9.


The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis.

Chen HJ, Mitchell JC, Novoselov S, Miller J, Nishimura AL, Scotter EL, Vance CA, Cheetham ME, Shaw CE.

Brain. 2016 May;139(Pt 5):1417-32. doi: 10.1093/brain/aww028. Epub 2016 Mar 1.


CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites.

Cimermancic P, Weinkam P, Rettenmaier TJ, Bichmann L, Keedy DA, Woldeyes RA, Schneidman-Duhovny D, Demerdash ON, Mitchell JC, Wells JA, Fraser JS, Sali A.

J Mol Biol. 2016 Feb 22;428(4):709-719. doi: 10.1016/j.jmb.2016.01.029. Epub 2016 Feb 5.


Variation in Location of the Mandibular Foramen/Inferior Alveolar Nerve Complex Given Anatomic Landmarks Using Cone-beam Computed Tomographic Scans.

Blacher J, Van DaHuvel S, Parashar V, Mitchell JC.

J Endod. 2016 Mar;42(3):393-6. doi: 10.1016/j.joen.2015.12.009. Epub 2016 Jan 16.


Bioactive glass fillers reduce bacterial penetration into marginal gaps for composite restorations.

Khvostenko D, Hilton TJ, Ferracane JL, Mitchell JC, Kruzic JJ.

Dent Mater. 2016 Jan;32(1):73-81. doi: 10.1016/ Epub 2015 Nov 24.


Effects of Oxide Layer on the Bonding Strength of Ni-Cr Alloys with Porcelain Ceramics.

Park WU, Jung SH, Zhao J, Hwang KH, Lee JK, Mitchell JC.

J Nanosci Nanotechnol. 2015 Aug;15(8):5901-4.


Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties.

Rudrangi SR, Trivedi V, Mitchell JC, Wicks SR, Alexander BD.

Int J Pharm. 2015 Oct 15;494(1):408-16. doi: 10.1016/j.ijpharm.2015.08.062. Epub 2015 Aug 24.


Development and functional characterization of alginate dressing as potential protein delivery system for wound healing.

Momoh FU, Boateng JS, Richardson SC, Chowdhry BZ, Mitchell JC.

Int J Biol Macromol. 2015 Nov;81:137-50. doi: 10.1016/j.ijbiomac.2015.07.037. Epub 2015 Jul 26.


Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.

Mitchell JC, Constable R, So E, Vance C, Scotter E, Glover L, Hortobagyi T, Arnold ES, Ling SC, McAlonis M, Da Cruz S, Polymenidou M, Tessarolo L, Cleveland DW, Shaw CE.

Acta Neuropathol Commun. 2015 Jun 25;3:36. doi: 10.1186/s40478-015-0212-4.


Sol-gel-derived bioactive glasses demonstrate antimicrobial effects on common oral bacteria.

Salehi S, Davis HB, Ferracane JL, Mitchell JC.

Am J Dent. 2015 Apr;28(2):111-5.


Sex Differences in Affective Expression Among Individuals with Psychometrically Defined Schizotypy: Diagnostic Implications.

Mitchell JC, Ragsdale KA, Bedwell JS, Beidel DC, Cassisi JE.

Appl Psychophysiol Biofeedback. 2015 Sep;40(3):173-81. doi: 10.1007/s10484-015-9283-z.


Cyclic mechanical loading promotes bacterial penetration along composite restoration marginal gaps.

Khvostenko D, Salehi S, Naleway SE, Hilton TJ, Ferracane JL, Mitchell JC, Kruzic JJ.

Dent Mater. 2015 Jun;31(6):702-10. doi: 10.1016/ Epub 2015 Apr 18.


Interolog interfaces in protein-protein docking.

Alsop JD, Mitchell JC.

Proteins. 2015 Nov;83(11):1940-6. doi: 10.1002/prot.24788. Epub 2015 Sep 29.


Influence of the preparation method on the physicochemical properties of indomethacin and methyl-β-cyclodextrin complexes.

Rudrangi SR, Bhomia R, Trivedi V, Vine GJ, Mitchell JC, Alexander BD, Wicks SR.

Int J Pharm. 2015 Feb 20;479(2):381-90. doi: 10.1016/j.ijpharm.2015.01.010. Epub 2015 Jan 8.


Cytotoxicity of resin composites containing bioactive glass fillers.

Salehi S, Gwinner F, Mitchell JC, Pfeifer C, Ferracane JL.

Dent Mater. 2015 Feb;31(2):195-203. doi: 10.1016/ Epub 2015 Jan 3.


Novel mutations support a role for Profilin 1 in the pathogenesis of ALS.

Smith BN, Vance C, Scotter EL, Troakes C, Wong CH, Topp S, Maekawa S, King A, Mitchell JC, Lund K, Al-Chalabi A, Ticozzi N, Silani V, Sapp P, Brown RH Jr, Landers JE, Al-Sarraj S, Shaw CE.

Neurobiol Aging. 2015 Mar;36(3):1602.e17-27. doi: 10.1016/j.neurobiolaging.2014.10.032. Epub 2014 Oct 31.


Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.

Lohman DC, Forouhar F, Beebe ET, Stefely MS, Minogue CE, Ulbrich A, Stefely JA, Sukumar S, Luna-Sánchez M, Jochem A, Lew S, Seetharaman J, Xiao R, Wang H, Westphall MS, Wrobel RL, Everett JK, Mitchell JC, López LC, Coon JJ, Tong L, Pagliarini DJ.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4697-705. doi: 10.1073/pnas.1413128111. Epub 2014 Oct 22.


Detection of pathogenic Batrachochytrium dendrobatidis using water filtration, animal and bait testing.

Wimsatt J, Feldman SH, Heffron M, Hammond M, Ruehling MP, Grayson KL, Mitchell JC.

Zoo Biol. 2014 Nov-Dec;33(6):577-85. doi: 10.1002/zoo.21154. Epub 2014 Sep 17.


Structural analysis and modeling reveals new mechanisms governing ESCRT-III spiral filament assembly.

Shen QT, Schuh AL, Zheng Y, Quinney K, Wang L, Hanna M, Mitchell JC, Otegui MS, Ahlquist P, Cui Q, Audhya A.

J Cell Biol. 2014 Sep 15;206(6):763-77. doi: 10.1083/jcb.201403108. Epub 2014 Sep 8.


Speech prosody abnormalities and specific dimensional schizotypy features: are relationships limited to male participants?

Bedwell JS, Cohen AS, Trachik BJ, Deptula AE, Mitchell JC.

J Nerv Ment Dis. 2014 Oct;202(10):745-51. doi: 10.1097/NMD.0000000000000184.


The utility of the Dementia Severity Rating Scale in differentiating mild cognitive impairment and Alzheimer disease from controls.

Mitchell JC, Dick MB, Wood AE, Tapp AM, Ziegler R.

Alzheimer Dis Assoc Disord. 2015 Jul-Sep;29(3):222-8. doi: 10.1097/WAD.0000000000000057.


Subtypes of anhedonia and facial electromyography response to negative affective pictures in non-psychiatric adults.

Kadison LS, Ragsdale KA, Mitchell JC, Cassisi JE, Bedwell JS.

Cogn Neuropsychiatry. 2015;20(1):31-40. doi: 10.1080/13546805.2014.955172. Epub 2014 Sep 4.


Ion release from, and fluoride recharge of a composite with a fluoride-containing bioactive glass.

Davis HB, Gwinner F, Mitchell JC, Ferracane JL.

Dent Mater. 2014 Oct;30(10):1187-94. doi: 10.1016/ Epub 2014 Aug 28.


Functional characterisation and permeation studies of lyophilised thiolated chitosan xerogels for buccal delivery of insulin.

Boateng JS, Mitchell JC, Pawar H, Ayensu I.

Protein Pept Lett. 2014;21(11):1163-75.


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