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Items: 1 to 50 of 614

1.

A bioassay system of autologous human endothelial, smooth muscle cells, and leukocytes for use in drug discovery, phenotyping, and tissue engineering.

Ahmetaj-Shala B, Kawai R, Marei I, Nikolakopoulou Z, Shih CC, Konain B, Reed DM, Mongey R, Kirkby NS, Mitchell JA.

FASEB J. 2020 Jan;34(1):1745-1754. doi: 10.1096/fj.201901379RR. Epub 2019 Dec 5.

PMID:
31914612
2.

Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis.

Kirkby NS, Raouf J, Ahmetaj-Shala B, Liu B, Mazi SI, Edin ML, Chambers MG, Korotkova M, Wang X, Wahli W, Zeldin DC, Nüsing R, Zhou Y, Jakobsson PJ, Mitchell JA.

Cardiovasc Res. 2019 Nov 5. pii: cvz290. doi: 10.1093/cvr/cvz290. [Epub ahead of print]

PMID:
31688905
3.

Targeting Sleep Duration and Timing for Prevention of Adolescent Obesity.

Mitchell JA, Williamson A, Fiks AG.

JAMA Pediatr. 2019 Sep 16. doi: 10.1001/jamapediatrics.2019.3080. [Epub ahead of print] No abstract available.

PMID:
31524928
4.

Cell-Specific Gene Deletion Reveals the Antithrombotic Function of COX1 and Explains the Vascular COX1/Prostacyclin Paradox.

Mitchell JA, Shala F, Elghazouli Y, Warner TD, Gaston-Massuet C, Crescente M, Armstrong PC, Herschman HR, Kirkby NS.

Circ Res. 2019 Oct 11;125(9):847-854. doi: 10.1161/CIRCRESAHA.119.314927. Epub 2019 Sep 12.

5.

Genes responsive to rapamycin and serum deprivation are clustered on chromosomes and undergo re-organization within local chromatin environments.

Belak ZR, Pickering JA, Gillespie ZE, Audette GF, Eramian M, Mitchell JA, Bridger JM, Kusalik A, Eskiw CH.

Biochem Cell Biol. 2019 Sep 3. doi: 10.1139/bcb-2019-0096. [Epub ahead of print]

PMID:
31479623
6.

Improving the Monitoring of Cardiac Rehabilitation Delivery and Quality: A Call to Action for Australia.

Thomas E, Astley C, Gallagher R, Foreman R, Mitchell JA, Grace SL, Cadilhac DA, Bunker S, Clark A, O'Neil A.

Heart Lung Circ. 2020 Jan;29(1):1-4. doi: 10.1016/j.hlc.2019.07.013. Epub 2019 Aug 16. No abstract available.

PMID:
31466852
7.

Defining a pathological role for the vasculature in the development of fibrosis and pulmonary hypertension in interstitial lung disease.

George PM, Mitchell JA.

Am J Physiol Lung Cell Mol Physiol. 2019 Oct 1;317(4):L431-L433. doi: 10.1152/ajplung.00330.2019. Epub 2019 Aug 21. No abstract available.

PMID:
31432711
8.

EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype.

Ciano M, Mantellato G, Connolly M, Paul-Clark M, Willis-Owen S, Moffatt MF, Cookson WOCM, Mitchell JA, Polkey MI, Hughes SM, Kemp PR, Natanek SA.

Sci Rep. 2019 Jun 25;9(1):9218. doi: 10.1038/s41598-019-45567-4.

9.

KLF4 protein stability regulated by interaction with pluripotency transcription factors overrides transcriptional control.

Dhaliwal NK, Abatti LE, Mitchell JA.

Genes Dev. 2019 Aug 1;33(15-16):1069-1082. doi: 10.1101/gad.324319.119. Epub 2019 Jun 20.

PMID:
31221664
10.

Pluripotency on Lockdown after Deletion of Three Transcription Regulators.

Mitchell JA.

Cell Stem Cell. 2019 May 2;24(5):681-683. doi: 10.1016/j.stem.2019.04.008.

PMID:
31051130
11.

The Role of Age and Multimorbidity in Shaping Older African American Men's Experiences with Patient⁻Provider Communication.

Perry RG, Mitchell JA, Hawkins J, Johnson-Lawrence V.

Geriatrics (Basel). 2018 Oct 24;3(4). pii: E74. doi: 10.3390/geriatrics3040074.

12.

Imaging of Tissue-Specific and Temporal Activation of GPCR Signaling Using DREADD Knock-In Mice.

Akhmedov D, Kirkby NS, Mitchell JA, Berdeaux R.

Methods Mol Biol. 2019;1947:361-376. doi: 10.1007/978-1-4939-9121-1_21.

13.

Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors.

Szczepanski A, Owczarek K, Bzowska M, Gula K, Drebot I, Ochman M, Maksym B, Rajfur Z, Mitchell JA, Pyrc K.

Viruses. 2019 Apr 5;11(4). pii: E328. doi: 10.3390/v11040328.

14.

Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2.

Lucotti S, Cerutti C, Soyer M, Gil-Bernabé AM, Gomes AL, Allen PD, Smart S, Markelc B, Watson K, Armstrong PC, Mitchell JA, Warner TD, Ridley AJ, Muschel RJ.

J Clin Invest. 2019 Mar 25;129(5):1845-1862. doi: 10.1172/JCI121985. eCollection 2019 Mar 25.

15.

Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors.

Kaczmarski JA, Mitchell JA, Spence MA, Vongsouthi V, Jackson CJ.

Curr Opin Struct Biol. 2019 Aug;57:31-38. doi: 10.1016/j.sbi.2019.01.013. Epub 2019 Feb 27. Review.

PMID:
30825845
16.

Associations Between Timing of Meals, Physical Activity, Light Exposure, and Sleep With Body Mass Index in Free-Living Adults.

Marinac CR, Quante M, Mariani S, Weng J, Redline S, Cespedes Feliciano EM, Hipp JA, Wang D, Kaplan ER, James P, Mitchell JA.

J Phys Act Health. 2019 Mar 1;16(3):214-221. doi: 10.1123/jpah.2017-0389. Epub 2019 Feb 24.

17.

Variational infinite heterogeneous mixture model for semi-supervised clustering of heart enhancers.

Mehdi TF, Singh G, Mitchell JA, Moses AM.

Bioinformatics. 2019 Sep 15;35(18):3232-3239. doi: 10.1093/bioinformatics/btz064.

18.

Postmenopausal osteoporotic fracture-associated COLIA1 variant impacts bone accretion in girls.

Cousminer DL, McCormack SE, Mitchell JA, Chesi A, Kindler JM, Kelly A, Voight BF, Kalkwarf HJ, Lappe JM, Shepherd JA, Oberfield SE, Gilsanz V, Zemel BS, Grant SFA.

Bone. 2019 Apr;121:221-226. doi: 10.1016/j.bone.2019.01.026. Epub 2019 Jan 31.

19.

Commentary on "What Attracts Medical Students to Primary Care? A Nominal Group Evaluation".

Mitchell JA, Rodríguez JE.

South Med J. 2019 Feb;112(2):83-84. doi: 10.14423/SMJ.0000000000000934. No abstract available.

PMID:
30708370
20.

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Manousaki D, Dudding T, Haworth S, Hsu YH, Liu CT, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Ikram MA, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, de Groot LCPGM, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards JB.

Am J Hum Genet. 2018 Dec 6;103(6):1053. doi: 10.1016/j.ajhg.2018.11.010. No abstract available.

21.

Preventing bronchopulmonary dysplasia: new tools for an old challenge.

Álvarez-Fuente M, Moreno L, Mitchell JA, Reiss IK, Lopez P, Elorza D, Duijts L, Avila-Alvarez A, Arruza L, Ramirez Orellana M, Baraldi E, Zaramella P, Rueda S, Gimeno-Díaz de Atauri Á, Guimarães H, Rocha G, Proença E, Thébaud B, Del Cerro MJ.

Pediatr Res. 2019 Mar;85(4):432-441. doi: 10.1038/s41390-018-0228-0. Epub 2018 Nov 21. Review.

PMID:
30464331
22.

Zeitgebers and their association with rest-activity patterns.

Quante M, Mariani S, Weng J, Marinac CR, Kaplan ER, Rueschman M, Mitchell JA, James P, Hipp JA, Cespedes Feliciano EM, Wang R, Redline S.

Chronobiol Int. 2019 Feb;36(2):203-213. doi: 10.1080/07420528.2018.1527347. Epub 2018 Oct 26.

PMID:
30365354
23.

PPARβ/δ a potential target in pulmonary hypertension blighted by cancer risk.

Mitchell JA, Bishop-Bailey D.

Pulm Circ. 2019 Jan-Mar;9(1):2045894018812053. doi: 10.1177/2045894018812053. Epub 2018 Oct 23. No abstract available.

24.

Body Mass Index Is a Better Indicator of Body Composition than Weight-for-Length at Age 1 Month.

Roy SM, Fields DA, Mitchell JA, Hawkes CP, Kelly A, Wu GD, DeRusso PA, Elovitz MA, Ford E, Drigo D, Zemel BS, McCormack SE.

J Pediatr. 2019 Jan;204:77-83.e1. doi: 10.1016/j.jpeds.2018.08.007. Epub 2018 Sep 26.

25.

Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping.

Ahmetaj-Shala B, Olanipekun M, Tesfai A, MacCallum N, Kirkby NS, Quinlan GJ, Shih CC, Kawai R, Mumby S, Paul-Clark M, Want EJ, Mitchell JA.

Sci Rep. 2018 Sep 18;8(1):13987. doi: 10.1038/s41598-018-31055-8.

26.

Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS.

Zhang WH, Herde MK, Mitchell JA, Whitfield JH, Wulff AB, Vongsouthi V, Sanchez-Romero I, Gulakova PE, Minge D, Breithausen B, Schoch S, Janovjak H, Jackson CJ, Henneberger C.

Nat Chem Biol. 2018 Sep;14(9):861-869. doi: 10.1038/s41589-018-0108-2. Epub 2018 Jul 30.

PMID:
30061718
27.

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells.

Szczepanski A, Owczarek K, Milewska A, Baster Z, Rajfur Z, Mitchell JA, Pyrc K.

Vet Res. 2018 Jul 3;49(1):55. doi: 10.1186/s13567-018-0551-9.

28.

Letter by Mitchell et al Regarding Article, "Urinary Prostaglandin Metabolites: An Incomplete Reckoning and a Flush to Judgment".

Mitchell JA, Knowles RB, Kirkby NS, Reed DM, Edin ML, White WE, Chan MV, Longhurst H, Yaqoob MM, Milne GL, Zeldin DC, Warner TD.

Circ Res. 2018 May 11;122(10):e84-e85. doi: 10.1161/CIRCRESAHA.118.312976. No abstract available.

29.

Changes in pediatric DXA measures of musculoskeletal outcomes and correlation with quantitative CT following treatment of acute lymphoblastic leukemia.

Mostoufi-Moab S, Kelly A, Mitchell JA, Baker J, Zemel BS, Brodsky J, Long J, Leonard MB.

Bone. 2018 Jul;112:128-135. doi: 10.1016/j.bone.2018.04.012. Epub 2018 Apr 19.

30.

Intergenerational Mobility and Goal-Striving Stress Among Black Americans: The Roles of Ethnicity and Nativity Status.

Mouzon DM, Watkins DC, Perry R, Simpson TM, Mitchell JA.

J Immigr Minor Health. 2019 Apr;21(2):393-400. doi: 10.1007/s10903-018-0735-4.

31.

Characterizing Mobility Limitations Among Older African American Men.

Mitchell JA, Johnson-Lawrence V, Williams EG, Thorpe R Jr.

J Natl Med Assoc. 2018 Apr;110(2):190-196. doi: 10.1016/j.jnma.2017.05.002. Epub 2017 Jun 7.

32.

KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency.

Dhaliwal NK, Miri K, Davidson S, Tamim El Jarkass H, Mitchell JA.

Stem Cell Reports. 2018 Apr 10;10(4):1308-1323. doi: 10.1016/j.stemcr.2018.02.007. Epub 2018 Mar 8.

33.

Eicosanoids, prostacyclin and cyclooxygenase in the cardiovascular system.

Mitchell JA, Kirkby NS.

Br J Pharmacol. 2019 Apr;176(8):1038-1050. doi: 10.1111/bph.14167. Epub 2018 Apr 14. Review.

34.

Physical Activity and Bone Accretion: Isotemporal Modeling and Genetic Interactions.

Mitchell JA, Chesi A, McCormack SE, Cousminer DL, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SFA, Zemel BS.

Med Sci Sports Exerc. 2018 May;50(5):977-986. doi: 10.1249/MSS.0000000000001520.

35.

Enzyme and Cancer Cell Selectivity of Nanoparticles: Inhibition of 3D Metastatic Phenotype and Experimental Melanoma by Zinc Oxide.

DeLong RK, Mitchell JA, Morris RT, Comer J, Hurst MN, Ghosh K, Wanekaya A, Mudge M, Schaeffer A, Washington LL, Risor-Marhanka A, Thomas S, Marroquin S, Lekey A, Smith JJ, Garrad R, Aryal S, Abdelhakiem M, Glaspell GP.

J Biomed Nanotechnol. 2017 Feb;13(2):221-31.

PMID:
29377653
36.

The thalamus in drug addiction: from rodents to humans.

Huang AS, Mitchell JA, Haber SN, Alia-Klein N, Goldstein RZ.

Philos Trans R Soc Lond B Biol Sci. 2018 Mar 19;373(1742). pii: 20170028. doi: 10.1098/rstb.2017.0028. Review.

37.

Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.

Mitchell JA, Knowles RB, Kirkby NS, Reed DM, Edin ML, White WE, Chan MV, Longhurst H, Yaqoob MM, Milne GL, Zeldin DC, Warner TD.

Circ Res. 2018 Feb 16;122(4):555-559. doi: 10.1161/CIRCRESAHA.117.312144. Epub 2018 Jan 3.

38.

Cyclooxygenase-2 Selectively Controls Renal Blood Flow Through a Novel PPARβ/δ-Dependent Vasodilator Pathway.

Kirkby NS, Sampaio W, Etelvino G, Alves DT, Anders KL, Temponi R, Shala F, Nair AS, Ahmetaj-Shala B, Jiao J, Herschman HR, Wang X, Wahli W, Santos RA, Mitchell JA.

Hypertension. 2018 Feb;71(2):297-305. doi: 10.1161/HYPERTENSIONAHA.117.09906. Epub 2018 Jan 2. Erratum in: Hypertension. 2018 Mar;71(3):e10.

39.

Moving effective treatment for posttraumatic stress disorder to primary care: A randomized controlled trial with active duty military.

Cigrang JA, Rauch SA, Mintz J, Brundige AR, Mitchell JA, Najera E, Litz BT, Young-McCaughan S, Roache JD, Hembree EA, Goodie JL, Sonnek SM, Peterson AL; STRONG STAR Consortium.

Fam Syst Health. 2017 Dec;35(4):450-462. doi: 10.1037/fsh0000315.

PMID:
29283612
40.

Multidimensional Bone Density Phenotyping Reveals New Insights Into Genetic Regulation of the Pediatric Skeleton.

Mitchell JA, Chesi A, Cousminer DL, McCormack SE, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Zemel BS, Grant SF.

J Bone Miner Res. 2018 May;33(5):812-821. doi: 10.1002/jbmr.3362. Epub 2018 Mar 30.

41.

Adaptation of Bone to Mechanical Strain-Reply.

McCormack SE, Mitchell JA, Zemel BS.

JAMA Pediatr. 2018 Feb 1;172(2):196-197. doi: 10.1001/jamapediatrics.2017.4654. No abstract available.

PMID:
29228153
42.

European surveillance of emerging pathogens associated with canine infectious respiratory disease.

Mitchell JA, Cardwell JM, Leach H, Walker CA, Le Poder S, Decaro N, Rusvai M, Egberink H, Rottier P, Fernandez M, Fragkiadaki E, Shields S, Brownlie J.

Vet Microbiol. 2017 Dec;212:31-38. doi: 10.1016/j.vetmic.2017.10.019. Epub 2017 Oct 28.

PMID:
29173585
43.

Genetically Determined Later Puberty Impacts Lowered Bone Mineral Density in Childhood and Adulthood.

Cousminer DL, Mitchell JA, Chesi A, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, McCormack SE, Voight BF, Zemel BS, Grant SF.

J Bone Miner Res. 2018 Mar;33(3):430-436. doi: 10.1002/jbmr.3320. Epub 2017 Nov 17.

44.

Actigraphy-Derived Daily Rest-Activity Patterns and Body Mass Index in Community-Dwelling Adults.

Cespedes Feliciano EM, Quante M, Weng J, Mitchell JA, James P, Marinac CR, Mariani S, Redline S, Kerr J, Godbole S, Manteiga A, Wang D, Hipp JA.

Sleep. 2017 Dec 1;40(12). doi: 10.1093/sleep/zsx168.

45.

The Paradoxical Impact of Companionship on the Mental Health of Older African American Men.

Mitchell JA, Cadet T, Burke S, Williams ED, Alvarez D.

J Gerontol B Psychol Sci Soc Sci. 2018 Jan 11;73(2):230-239. doi: 10.1093/geronb/gbx089.

46.

Perceptions and receptivity of non-spousal family support: A mixed methods study of psychological distress among older, church-going African American men.

Watkins DC, Wharton T, Mitchell JA, Matusko N, Kales H.

J Mix Methods Res. 2017 Oct 1;11(4):487-509. doi: 10.1177/1558689815622707. Epub 2015 Dec 30.

47.

Metabolomic profiling of amines in sepsis predicts changes in NOS canonical pathways.

Tesfai A, MacCallum N, Kirkby NS, Gashaw H, Gray N, Want E, Quinlan GJ, Mumby S, Leiper JM, Paul-Clark M, Ahmetaj-Shala B, Mitchell JA.

PLoS One. 2017 Aug 15;12(8):e0183025. doi: 10.1371/journal.pone.0183025. eCollection 2017.

48.

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Manousaki D, Dudding T, Haworth S, Hsu YH, Liu CT, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Ikram MA, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, de Groot LCPGM, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards JB.

Am J Hum Genet. 2017 Aug 3;101(2):227-238. doi: 10.1016/j.ajhg.2017.06.014. Epub 2017 Jul 27. Erratum in: Am J Hum Genet. 2018 Dec 6;103(6):1053.

49.

Capturing the Dynamics of a Spring-Loaded Protein.

Mitchell JA, O'Mara ML.

Structure. 2017 Jul 5;25(7):963-964. doi: 10.1016/j.str.2017.06.008.

50.

Association Between Linear Growth and Bone Accrual in a Diverse Cohort of Children and Adolescents.

McCormack SE, Cousminer DL, Chesi A, Mitchell JA, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Winer KK, Kelly A, Grant SFA, Zemel BS.

JAMA Pediatr. 2017 Sep 5;171(9):e171769. doi: 10.1001/jamapediatrics.2017.1769. Epub 2017 Sep 5.

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