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Experimental translocations to low predation lead to non-parallel increases in relative brain size.

Mitchell DJ, Vega-Trejo R, Kotrschal A.

Biol Lett. 2020 Jan;16(1):20190654. doi: 10.1098/rsbl.2019.0654. Epub 2020 Jan 22.


Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening.

Wellaway CR, Amans D, Bamborough P, Barnett H, Bit RA, Brown JA, Carlson NR, Chung CW, Cooper AWJ, Craggs PD, Davis RP, Dean TW, Evans JP, Gordon L, Harada IL, Hirst DJ, Humphreys PG, Jones KL, Lewis AJ, Lindon MJ, Lugo D, Mahmood M, McCleary S, Medeiros P, Mitchell DJ, O'Sullivan M, Le Gall A, Patel VK, Patten C, Poole DL, Shah RR, Smith JE, Stafford KAJ, Thomas PJ, Vimal M, Wall ID, Watson RJ, Wellaway N, Yao G, Prinjha RK.

J Med Chem. 2020 Jan 23;63(2):714-746. doi: 10.1021/acs.jmedchem.9b01670. Epub 2020 Jan 6.


The effect of rule retrieval on activity in the default mode network.

Smith V, Mitchell DJ, Duncan J.

Neuroimage. 2019 Nov 15;202:116088. doi: 10.1016/j.neuroimage.2019.116088. Epub 2019 Aug 10.


A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification.

Bamborough P, Chung CW, Demont EH, Bridges AM, Craggs PD, Dixon DP, Francis P, Furze RC, Grandi P, Jones EJ, Karamshi B, Locke K, Lucas SCC, Michon AM, Mitchell DJ, Pogány P, Prinjha RK, Rau C, Roa AM, Roberts AD, Sheppard RJ, Watson RJ.

J Med Chem. 2019 Aug 22;62(16):7506-7525. doi: 10.1021/acs.jmedchem.9b00673. Epub 2019 Aug 9.


Progressive Recruitment of the Frontoparietal Multiple-demand System with Increased Task Complexity, Time Pressure, and Reward.

Shashidhara S, Mitchell DJ, Erez Y, Duncan J.

J Cogn Neurosci. 2019 Nov;31(11):1617-1630. doi: 10.1162/jocn_a_01440. Epub 2019 Jul 5.


The time-course of component processes of selective attention.

Wen T, Duncan J, Mitchell DJ.

Neuroimage. 2019 Oct 1;199:396-407. doi: 10.1016/j.neuroimage.2019.05.067. Epub 2019 May 29.


Aiming to Miss a Moving Target: Bromo and Extra Terminal Domain (BET) Selectivity in Constrained ATAD2 Inhibitors.

Bamborough P, Chung CW, Furze RC, Grandi P, Michon AM, Watson RJ, Mitchell DJ, Barnett H, Prinjha RK, Rau C, Sheppard RJ, Werner T, Demont EH.

J Med Chem. 2018 Sep 27;61(18):8321-8336. doi: 10.1021/acs.jmedchem.8b00862. Epub 2018 Sep 18.


Functional reorganisation and recovery following cortical lesions: A preliminary study in macaque monkeys.

Ainsworth M, Browncross H, Mitchell DJ, Mitchell AS, Passingham RE, Buckley MJ, Duncan J, Bell AH.

Neuropsychologia. 2018 Oct;119:382-391. doi: 10.1016/j.neuropsychologia.2018.08.024. Epub 2018 Sep 12.


From corps to discipline, part one: Charles d'Almeida, Pierre Bertin and French experimental physics, 1840-1880.

Mitchell DJ.

Br J Hist Sci. 2018 Sep;51(3):333-368. doi: 10.1017/S0007087418000535.


Bayesian updating during development predicts genotypic differences in plasticity.

Stamps JA, Biro PA, Mitchell DJ, Saltz JB.

Evolution. 2018 Oct;72(10):2167-2180. doi: 10.1111/evo.13585. Epub 2018 Sep 5.


Visual short-term memory through the lifespan: Preserved benefits of context and metacognition.

Mitchell DJ, Cusack R; Cam-CAN.

Psychol Aging. 2018 Aug;33(5):841-854. doi: 10.1037/pag0000265.


Role of the Default Mode Network in Cognitive Transitions.

Smith V, Mitchell DJ, Duncan J.

Cereb Cortex. 2018 Oct 1;28(10):3685-3696. doi: 10.1093/cercor/bhy167.


Response of the multiple-demand network during simple stimulus discriminations.

Wen T, Mitchell DJ, Duncan J.

Neuroimage. 2018 Aug 15;177:79-87. doi: 10.1016/j.neuroimage.2018.05.019. Epub 2018 May 10.


Methodologies for the airbrush application of MALDI matrices.

Warren AD, Mitchell DJ, Gates PJ.

Eur J Mass Spectrom (Chichester). 2018 Feb;24(1):89-95. doi: 10.1177/1469066717750031.


The making of measurement: Editors' introduction.

Mitchell DJ, Tal E, Chang H.

Stud Hist Philos Sci. 2017 Oct - Dec;65-66:1-7. doi: 10.1016/j.shpsa.2017.10.001.


Is behavioural plasticity consistent across different environmental gradients and through time?

Mitchell DJ, Biro PA.

Proc Biol Sci. 2017 Aug 16;284(1860). pii: 20170893. doi: 10.1098/rspb.2017.0893.


The neural basis of precise visual short-term memory for complex recognisable objects.

Veldsman M, Mitchell DJ, Cusack R.

Neuroimage. 2017 Oct 1;159:131-145. doi: 10.1016/j.neuroimage.2017.07.033. Epub 2017 Jul 17.


Correction: Recruitment of the default mode network during a demanding act of executive control.

Crittenden BM, Mitchell DJ, Duncan J.

Elife. 2017 Jun 5;6. pii: e29017. doi: 10.7554/eLife.29017. No abstract available.


Complexity and compositionality in fluid intelligence.

Duncan J, Chylinski D, Mitchell DJ, Bhandari A.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5295-5299. doi: 10.1073/pnas.1621147114. Epub 2017 May 1.


Towards powerful experimental and statistical approaches to study intraindividual variability in labile traits.

Mitchell DJ, Fanson BG, Beckmann C, Biro PA.

R Soc Open Sci. 2016 Oct 26;3(10):160352. eCollection 2016 Oct.


A Putative Multiple-Demand System in the Macaque Brain.

Mitchell DJ, Bell AH, Buckley MJ, Mitchell AS, Sallet J, Duncan J.

J Neurosci. 2016 Aug 17;36(33):8574-85. doi: 10.1523/JNEUROSCI.0810-16.2016.


A Chemical Probe for the ATAD2 Bromodomain.

Bamborough P, Chung CW, Demont EH, Furze RC, Bannister AJ, Che KH, Diallo H, Douault C, Grandi P, Kouzarides T, Michon AM, Mitchell DJ, Prinjha RK, Rau C, Robson S, Sheppard RJ, Upton R, Watson RJ.

Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11382-6. doi: 10.1002/anie.201603928. Epub 2016 Aug 17.


GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain.

Bamborough P, Barnett HA, Becher I, Bird MJ, Chung CW, Craggs PD, Demont EH, Diallo H, Fallon DJ, Gordon LJ, Grandi P, Hobbs CI, Hooper-Greenhill E, Jones EJ, Law RP, Le Gall A, Lugo D, Michon AM, Mitchell DJ, Prinjha RK, Sheppard RJ, Watson AJ, Watson RJ.

ACS Med Chem Lett. 2016 May 9;7(6):552-7. doi: 10.1021/acsmedchemlett.6b00092. eCollection 2016 Jun 9.


Task Encoding across the Multiple Demand Cortex Is Consistent with a Frontoparietal and Cingulo-Opercular Dual Networks Distinction.

Crittenden BM, Mitchell DJ, Duncan J.

J Neurosci. 2016 Jun 8;36(23):6147-55. doi: 10.1523/JNEUROSCI.4590-15.2016. Erratum in: J Neurosci. 2017 Jun 28;37(26):6388.


Neural Coding for Instruction-Based Task Sets in Human Frontoparietal and Visual Cortex.

Muhle-Karbe PS, Duncan J, De Baene W, Mitchell DJ, Brass M.

Cereb Cortex. 2017 Mar 1;27(3):1891-1905. doi: 10.1093/cercor/bhw032.


Semantic and emotional content of imagined representations in human occipitotemporal cortex.

Mitchell DJ, Cusack R.

Sci Rep. 2016 Feb 3;6:20232. doi: 10.1038/srep20232.


Live cell imaging of cytoplasmic dynein movement in transfected embryonic rat neurons.

Ross MW, Mitchell DJ, Cain JC, Blasier KR, Pfister KK.

Methods Cell Biol. 2016;131:253-67. doi: 10.1016/bs.mcb.2015.06.020. Epub 2015 Sep 2.


Training refines brain representations for multitasking.

Duncan J, Mitchell DJ.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14127-8. doi: 10.1073/pnas.1518636112. Epub 2015 Oct 29. No abstract available.


Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors.

Bamborough P, Chung CW, Furze RC, Grandi P, Michon AM, Sheppard RJ, Barnett H, Diallo H, Dixon DP, Douault C, Jones EJ, Karamshi B, Mitchell DJ, Prinjha RK, Rau C, Watson RJ, Werner T, Demont EH.

J Med Chem. 2015 Aug 13;58(15):6151-78. doi: 10.1021/acs.jmedchem.5b00773. Epub 2015 Jul 31.


Detection of Mild and Reversible Neurohistopathological Changes in the Brain of Juvenile (Preweaned) Beagle Dogs Treated with Vigabatrin for up to 91 Days.

Bottomley AL, Rowles A, Mitchell DJ, Rasmussen AD.

Toxicol Pathol. 2015 Oct;43(7):1015-24. doi: 10.1177/0192623315591838. Epub 2015 Jul 7.


Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.

Demont EH, Chung CW, Furze RC, Grandi P, Michon AM, Wellaway C, Barrett N, Bridges AM, Craggs PD, Diallo H, Dixon DP, Douault C, Emmons AJ, Jones EJ, Karamshi BV, Locke K, Mitchell DJ, Mouzon BH, Prinjha RK, Roberts AD, Sheppard RJ, Watson RJ, Bamborough P.

J Med Chem. 2015 Jul 23;58(14):5649-73. doi: 10.1021/acs.jmedchem.5b00772. Epub 2015 Jul 9.


Concurrent brain responses to separate auditory and visual targets.

Finoia P, Mitchell DJ, Hauk O, Beste C, Pizzella V, Duncan J.

J Neurophysiol. 2015 Aug;114(2):1239-47. doi: 10.1152/jn.01050.2014. Epub 2015 Jun 17.


Recruitment of the default mode network during a demanding act of executive control.

Crittenden BM, Mitchell DJ, Duncan J.

Elife. 2015 Apr 13;4:e06481. doi: 10.7554/eLife.06481. Erratum in: Elife. 2017 Jun 05;6:.


Automatic analysis (aa): efficient neuroimaging workflows and parallel processing using Matlab and XML.

Cusack R, Vicente-Grabovetsky A, Mitchell DJ, Wild CJ, Auer T, Linke AC, Peelle JE.

Front Neuroinform. 2015 Jan 15;8:90. doi: 10.3389/fninf.2014.00090. eCollection 2014.


Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking.

Kievit RA, Davis SW, Mitchell DJ, Taylor JR, Duncan J; Cam-CAN Research Team, Henson RN; Cam-CAN Research Team.

Nat Commun. 2014 Dec 18;5:5658. doi: 10.1038/ncomms6658.


1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain.

Demont EH, Bamborough P, Chung CW, Craggs PD, Fallon D, Gordon LJ, Grandi P, Hobbs CI, Hussain J, Jones EJ, Le Gall A, Michon AM, Mitchell DJ, Prinjha RK, Roberts AD, Sheppard RJ, Watson RJ.

ACS Med Chem Lett. 2014 Sep 10;5(11):1190-5. doi: 10.1021/ml5002932. eCollection 2014 Nov 13.


Expression of the orphan cytosolic sulfotransferase SULT4A1 and its major splice variant in human tissues and cells: dimerization, degradation and polyubiquitination.

Sidharthan NP, Butcher NJ, Mitchell DJ, Minchin RF.

PLoS One. 2014 Jul 2;9(7):e101520. doi: 10.1371/journal.pone.0101520. eCollection 2014.


Live cell imaging reveals differential modifications to cytoplasmic dynein properties by phospho- and dephosphomimic mutations of the intermediate chain 2C S84.

Blasier KR, Humsi MK, Ha J, Ross MW, Smiley WR, Inamdar NA, Mitchell DJ, Lo KW, Pfister KK.

J Neurosci Res. 2014 Sep;92(9):1143-54. doi: 10.1002/jnr.23388. Epub 2014 May 5.


Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport.

Mitchell DJ, Blasier KR, Jeffery ED, Ross MW, Pullikuth AK, Suo D, Park J, Smiley WR, Lo KW, Shabanowitz J, Deppmann CD, Trinidad JC, Hunt DF, Catling AD, Pfister KK.

J Neurosci. 2012 Oct 31;32(44):15495-510. doi: 10.1523/JNEUROSCI.5599-11.2012.


Implementation and testing of a multivariate inverse radiation transport solver.

Mattingly J, Mitchell DJ.

Appl Radiat Isot. 2012 Jul;70(7):1136-40. doi: 10.1016/j.apradiso.2011.10.020. Epub 2011 Nov 12.


The temporal evolution of electromagnetic markers sensitive to the capacity limits of visual short-term memory.

Mitchell DJ, Cusack R.

Front Hum Neurosci. 2011 Feb 15;5:18. doi: 10.3389/fnhum.2011.00018. eCollection 2011.


Seeing different objects in different ways: measuring ventral visual tuning to sensory and semantic features with dynamically adaptive imaging.

Cusack R, Veldsman M, Naci L, Mitchell DJ, Linke AC.

Hum Brain Mapp. 2012 Feb;33(2):387-97. doi: 10.1002/hbm.21219. Epub 2011 Mar 9.


The preferred priorities for care document in motor neurone disease: views of bereaved relatives and carers.

Preston H, Fineberg IC, Callagher P, Mitchell DJ.

Palliat Med. 2012 Mar;26(2):132-8. doi: 10.1177/0269216311399664. Epub 2011 Mar 7.


Encoding strategy accounts for individual differences in change detection measures of VSTM.

Linke AC, Vicente-Grabovetsky A, Mitchell DJ, Cusack R.

Neuropsychologia. 2011 May;49(6):1476-86. doi: 10.1016/j.neuropsychologia.2010.11.034. Epub 2010 Dec 3.


Phosphorylation/dephosphorylation of human SULT4A1: role of Erk1 and PP2A.

Mitchell DJ, Butcher NJ, Minchin RF.

Biochim Biophys Acta. 2011 Jan;1813(1):231-7. doi: 10.1016/j.bbamcr.2010.09.011. Epub 2010 Oct 12.


Regulation of mouse brain-selective sulfotransferase sult4a1 by cAMP response element-binding protein and activating transcription factor-2.

Butcher NJ, Mitchell DJ, Burow R, Minchin RF.

Mol Pharmacol. 2010 Sep;78(3):503-10. doi: 10.1124/mol.110.063404. Epub 2010 Jun 22.


Rydberg gas theory of a glow discharge plasma: I. Application to the electrical behaviour of a fast flowing glow discharge plasma.

Mason RS, Mitchell DJ, Dickinson PM.

Phys Chem Chem Phys. 2010 Apr 21;12(15):3698-717. doi: 10.1039/b918079f. Epub 2010 Feb 24.


Encoding strategy and not visual working memory capacity correlates with intelligence.

Cusack R, Lehmann M, Veldsman M, Mitchell DJ.

Psychon Bull Rev. 2009 Aug;16(4):641-7. doi: 10.3758/PBR.16.4.641.


Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.

Mitchell DJ, Minchin RF.

Mol Pharmacol. 2009 Aug;76(2):388-95. doi: 10.1124/mol.109.055442. Epub 2009 May 13.


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