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Grounding Value-Based Drug Pricing in Population Health.

Kaltenboeck A, Calsyn M, Frederix GWJ, Lowenthal J, Mitchell D, Rector B, Sarpatwari A.

Clin Pharmacol Ther. 2020 Jan 17. doi: 10.1002/cpt.1741. [Epub ahead of print] No abstract available.


Pain in Clients Attending a South African Voluntary Counseling and Testing Center Was Frequent and Extensive But Did Not Depend on HIV Status.

Wadley AL, Lazarus E, Gray GE, Mitchell D, Kamerman PR.

J Acquir Immune Defic Syndr. 2020 Feb 1;83(2):181-188. doi: 10.1097/QAI.0000000000002248.


Laparoscopic colectomies associated with decreased retrieval of 12 or more lymph nodes compared to open in elective colon cancer surgery.

Puckett Y, Mitchell D, Pham T.

Ecancermedicalscience. 2019 Oct 14;13:968. doi: 10.3332/ecancer.2019.968. eCollection 2019.


Case 1-2020: An 11-Year-Old Boy with Vomiting and Weight Loss.

Fasano A, Leonard MM, Mitchell DM, Eng G.

N Engl J Med. 2020 Jan 9;382(2):180-189. doi: 10.1056/NEJMcpc1913469. No abstract available.


Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening.

Wellaway CR, Amans D, Bamborough P, Barnett H, Bit RA, Brown JA, Carlson NR, Chung CW, Cooper AWJ, Craggs PD, Davis RP, Dean TW, Evans JP, Gordon L, Harada IL, Hirst DJ, Humphreys PG, Jones KL, Lewis AJ, Lindon MJ, Lugo D, Mahmood M, McCleary S, Medeiros P, Mitchell DJ, O'Sullivan M, Le Gall A, Patel VK, Patten C, Poole DL, Shah RR, Smith JE, Stafford KAJ, Thomas PJ, Vimal M, Wall ID, Watson RJ, Wellaway N, Yao G, Prinjha RK.

J Med Chem. 2020 Jan 6. doi: 10.1021/acs.jmedchem.9b01670. [Epub ahead of print]


Energetic Oxygen and Sulfur Charge States in the Outer Jovian Magnetosphere: Insights From the Cassini Jupiter Flyby.

Allen RC, Paranicas CP, Bagenal F, Vines SK, Hamilton DC, Allegrini F, Clark G, Delamere PA, Kim TK, Krimigis SM, Mitchell DG, Smith TH, Wilson RJ.

Geophys Res Lett. 2019 Nov 16;46(21):11709-11717. doi: 10.1029/2019GL085185. Epub 2019 Nov 8.


High-Energy (>10 MeV) Oxygen and Sulfur Ions Observed at Jupiter From Pulse Width Measurements of the JEDI Sensors.

Westlake JH, Clark G, Haggerty DK, Jaskulek SE, Kollmann P, Mauk BH, Mitchell DG, Nelson KS, Paranicas CP, Rymer AM.

Geophys Res Lett. 2019 Oct 28;46(20):10959-10966. doi: 10.1029/2019GL083842.


CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas.

Flores-Toro JA, Luo D, Gopinath A, Sarkisian MR, Campbell JJ, Charo IF, Singh R, Schall TJ, Datta M, Jain RK, Mitchell DA, Harrison JK.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1129-1138. doi: 10.1073/pnas.1910856117. Epub 2019 Dec 26.


The Expanding Burden of Acute Kidney Injury in California: Impact of the Epidemic of Diabetes on Kidney Injury Hospital Admissions.

Medel-Herrero A, Mitchell D, Moyce S, Udaltsova I, Schenker M.

Nephrol Nurs J. 2019 May-Jun;46(6):629-640.


Contemporary utilization patterns and outcomes of thrombolytic administration for ischemic stroke among patients with cancer.

Owusu-Guha J, Guha A, Miller PE, Pawar S, Dey AK, Ahmad T, Attar H, Awan FT, Mitchell D, Desai NR, Addison D.

Int J Stroke. 2019 Dec 22:1747493019895709. doi: 10.1177/1747493019895709. [Epub ahead of print]


Correction to "Orchestration of Enzymatic Processing by Thiazole/Oxazole-Modified Microcin Dehydrogenases".

Melby JO, Li X, Mitchell DA.

Biochemistry. 2019 Dec 19. doi: 10.1021/acs.biochem.9b01042. [Epub ahead of print] No abstract available.


Cyclin-dependent kinase 4 inhibits the translational repressor 4E-BP1 to promote cap-dependent translation during mitosis-G1 transition.

Mitchell DC, Menon A, Garner AL.

FEBS Lett. 2019 Dec 18. doi: 10.1002/1873-3468.13721. [Epub ahead of print]


APOBEC3A is a prominent cytidine deaminase in breast cancer.

Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA.

PLoS Genet. 2019 Dec 16;15(12):e1008545. doi: 10.1371/journal.pgen.1008545. eCollection 2019 Dec.


Ultradian oscillations in brain temperature in sheep: implications for thermoregulatory control?

Fuller A, Hetem RS, Meyer LCR, Mitchell D, Maloney SK.

J Comp Physiol B. 2019 Dec 13. doi: 10.1007/s00360-019-01248-2. [Epub ahead of print]


A Cost-Effectiveness Analysis of Glecaprevir/Pibrentasvir Versus Existing Direct-Acting Antivirals to Treat Chronic Hepatitis C in Japan.

Kawaguchi I, Chayama K, Gonzalez YS, Virabhak S, Mitchell D, Yuen C, Kumada H.

Adv Ther. 2020 Jan;37(1):457-476. doi: 10.1007/s12325-019-01166-3. Epub 2019 Dec 5.


Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy.

Flores C, Wildes T, Dean BD, Moore G, Drake J, Abraham R, Gil J, Yegorov O, Yang C, Dean J, Moneypenny C, Shin D, Pham C, Krauser J, King J, Grant G, Driscoll T, Kurtzberg J, McLendon R, Gururangan S, Mitchell D.

Sci Adv. 2019 Nov 27;5(11):eaav9879. doi: 10.1126/sciadv.aav9879. eCollection 2019 Nov.


Aurora B functions at the apical surface after specialized cytokinesis during morphogenesis in C. elegans.

Bai X, Melesse M, Sorensen Turpin CG, Sloan DE, Chen CY, Wang WC, Lee PY, Simmons JR, Nebenfuehr B, Mitchell D, Klebanow LR, Mattson N, Betzig E, Chen BC, Cheerambathur D, Bembenek JN.

Development. 2020 Jan 8;147(1). pii: dev181099. doi: 10.1242/dev.181099.


Retrospective comparison of EASL 2018 and LI-RADS 2018 for the noninvasive diagnosis of hepatocellular carcinoma using magnetic resonance imaging.

Lee S, Kim MJ, Kim SS, Shin H, Kim DY, Choi JY, Park MS, Mitchell DG.

Hepatol Int. 2019 Dec 4. doi: 10.1007/s12072-019-10002-3. [Epub ahead of print]


Probing the energetic particle environment near the Sun.

McComas DJ, Christian ER, Cohen CMS, Cummings AC, Davis AJ, Desai MI, Giacalone J, Hill ME, Joyce CJ, Krimigis SM, Labrador AW, Leske RA, Malandraki O, Matthaeus WH, McNutt RL Jr, Mewaldt RA, Mitchell DG, Posner A, Rankin JS, Roelof EC, Schwadron NA, Stone EC, Szalay JR, Wiedenbeck ME, Bale SD, Kasper JC, Case AW, Korreck KE, MacDowall RJ, Pulupa M, Stevens ML, Rouillard AP.

Nature. 2019 Dec;576(7786):223-227. doi: 10.1038/s41586-019-1811-1. Epub 2019 Dec 4.


Acute kidney injury and workload in a sample of California agricultural workers.

Moyce S, Armitage T, Mitchell D, Schenker M.

Am J Ind Med. 2019 Nov 26. doi: 10.1002/ajim.23076. [Epub ahead of print]


Analysis of the Potential for N4-Hydroxycytidine to Inhibit Mitochondrial Replication and Function.

Sticher ZM, Lu G, Mitchell DG, Marlow J, Moellering L, Bluemling GR, Guthrie DB, Natchus MG, Painter GR, Kolykhalov AA.

Antimicrob Agents Chemother. 2019 Nov 25. pii: AAC.01719-19. doi: 10.1128/AAC.01719-19. [Epub ahead of print]


Elevated HbA1c is associated with altered cortical and trabecular microarchitecture in girls with type 1 diabetes.

Mitchell DM, Caksa S, Joseph T, Bouxsein ML, Misra M.

J Clin Endocrinol Metab. 2019 Nov 25. pii: dgz221. doi: 10.1210/clinem/dgz221. [Epub ahead of print]


Metagenomics: Is it a powerful tool to obtain lipases for application in biocatalysis?

Almeida JM, Alnoch RC, Souza EM, Mitchell DA, Krieger N.

Biochim Biophys Acta Proteins Proteom. 2020 Feb;1868(2):140320. doi: 10.1016/j.bbapap.2019.140320. Epub 2019 Nov 20. Review.


Sarcosine promotes trafficking of dendritic cells and improves efficacy of anti-tumor dendritic cell vaccines via CXC chemokine family signaling.

Dastmalchi F, Karachi A, Yang C, Azari H, Sayour EJ, Dechkovskaia A, Vlasak AL, Saia ME, Lovaton RE, Mitchell DA, Rahman M.

J Immunother Cancer. 2019 Nov 21;7(1):321. doi: 10.1186/s40425-019-0809-4.


Mechanistic evaluation of biochar potential for plant growth promotion and alleviation of chromium-induced phytotoxicity in Ficus elastica.

Kumar A, Joseph S, Tsechansky L, Schreiter IJ, Schüth C, Taherysoosavi S, Mitchell DRG, Graber ER.

Chemosphere. 2019 Nov 11;243:125332. doi: 10.1016/j.chemosphere.2019.125332. [Epub ahead of print]


Evaluating the risk to humans from mineral oils in foods: Current state of the evidence.

Bevan R, Harrison PTC, Jeffery B, Mitchell D.

Food Chem Toxicol. 2019 Nov 18:110966. doi: 10.1016/j.fct.2019.110966. [Epub ahead of print] Review.


The Patient-Centered Future of Clinical Pharmacology.

Shahin MH, Abdel-Rahman S, Hartman D, Johnson JA, Mitchell DY, Reynolds KS, Wagner JA, Morrissey KM.

Clin Pharmacol Ther. 2020 Jan;107(1):72-75. doi: 10.1002/cpt.1681. Epub 2019 Nov 21. No abstract available.


Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging.

Grippin AJ, Wummer B, Wildes T, Dyson K, Trivedi V, Yang C, Sebastian M, Mendez-Gomez HR, Padala S, Grubb M, Fillingim M, Monsalve A, Sayour EJ, Dobson J, Mitchell DA.

ACS Nano. 2019 Dec 24;13(12):13884-13898. doi: 10.1021/acsnano.9b05037. Epub 2019 Dec 2.


Biochar bound urea boosts plant growth and reduces nitrogen leaching.

Shi W, Ju Y, Bian R, Li L, Joseph S, Mitchell DRG, Munroe P, Taherymoosavi S, Pan G.

Sci Total Environ. 2020 Jan 20;701:134424. doi: 10.1016/j.scitotenv.2019.134424. Epub 2019 Sep 12.


Dysregulation of glutamate transport enhances Treg function that promotes VEGF blockade resistance in glioblastoma.

Long Y, Tao H, Karachi A, Grippin AJ, Jin L, Chang YE, Zhang W, Dyson KA, Hou AY, Na M, Deleyrolle LP, Sayour EJ, Rahman M, Mitchell DA, Lin Z, Huang J.

Cancer Res. 2019 Nov 13. pii: canres.1577.2019. doi: 10.1158/0008-5472.CAN-19-1577. [Epub ahead of print]


Keeping cool in the heat: Behavioral thermoregulation and body temperature patterns in wild vervet monkeys.

McFarland R, Barrett L, Costello MA, Fuller A, Hetem RS, Maloney SK, Mitchell D, Henzi PS.

Am J Phys Anthropol. 2019 Nov 12. doi: 10.1002/ajpa.23962. [Epub ahead of print]


A case of concurrent systemic sclerosis and scleredema.

Mitchell DC, Agnihothri R, Scott GA, Korman B, Richardson CT.

JAAD Case Rep. 2019 Oct 24;5(11):940-942. doi: 10.1016/j.jdcr.2019.09.004. eCollection 2019 Nov. No abstract available.


Mandated Imaging Appropriate Use Criteria.

Mitchell DM.

Ann Intern Med. 2019 Nov 5;171(9):682. doi: 10.7326/L19-0531. No abstract available.


Safety, Tolerability, Pharmacokinetics, Target Occupancy, and Concentration-QT Analysis of the Novel BTK Inhibitor Evobrutinib in Healthy Volunteers.

Becker A, Martin EC, Mitchell DY, Grenningloh R, Bender AT, Laurent J, Mackenzie H, Johne A.

Clin Transl Sci. 2019 Oct 24. doi: 10.1111/cts.12713. [Epub ahead of print]


Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.

Toots M, Yoon JJ, Cox RM, Hart M, Sticher ZM, Makhsous N, Plesker R, Barrena AH, Reddy PG, Mitchell DG, Shean RC, Bluemling GR, Kolykhalov AA, Greninger AL, Natchus MG, Painter GR, Plemper RK.

Sci Transl Med. 2019 Oct 23;11(515). pii: eaax5866. doi: 10.1126/scitranslmed.aax5866.


Liver MR Elastography Technique and Image Interpretation: Pearls and Pitfalls.

Guglielmo FF, Venkatesh SK, Mitchell DG.

Radiographics. 2019 Nov-Dec;39(7):1983-2002. doi: 10.1148/rg.2019190034. Epub 2019 Oct 18.


The RNA-binding protein SART3 promotes miR-34a biogenesis and G1 cell cycle arrest in lung cancer cells.

Sherman EJ, Mitchell DC, Garner AL.

J Biol Chem. 2019 Nov 15;294(46):17188-17196. doi: 10.1074/jbc.AC119.010419. Epub 2019 Oct 16.


Platinum-based regimens versus cetuximab in definitive chemoradiation for human papillomavirus-unrelated head and neck cancer.

Beckham TH, Barney C, Healy E, Wolfe AR, Branstetter A, Yaney A, Riaz N, McBride SM, Tsai CJ, Kang J, Yu Y, Chen L, Sherman E, Dunn L, Pfister DG, Tan J, Rupert R, Bonomi M, Zhang Z, Lobaugh SM, Grecula JC, Mitchell DL, Wobb JL, Miller ED, Blakaj DM, Diavolitsis VM, Lee N, Bhatt AD.

Int J Cancer. 2019 Oct 14. doi: 10.1002/ijc.32736. [Epub ahead of print]


Characterising recovery from renal transplantation and live-related donation using cardiopulmonary exercise testing.

Angell J, Dodds N, Darweish-Mednuik AM, Lewis S, Pyke M, Mitchell DC, Hamilton K, White P, Tolchard S.

Disabil Rehabil. 2019 Oct 10:1-7. doi: 10.1080/09638288.2019.1674387. [Epub ahead of print]


Safety profile of autologous macrophage therapy for liver cirrhosis.

Moroni F, Dwyer BJ, Graham C, Pass C, Bailey L, Ritchie L, Mitchell D, Glover A, Laurie A, Doig S, Hargreaves E, Fraser AR, Turner ML, Campbell JDM, McGowan NWA, Barry J, Moore JK, Hayes PC, Leeming DJ, Nielsen MJ, Musa K, Fallowfield JA, Forbes SJ.

Nat Med. 2019 Oct;25(10):1560-1565. doi: 10.1038/s41591-019-0599-8. Epub 2019 Oct 7.


Ventricular volume expansion in presymptomatic genetic frontotemporal dementia.

Tavares TP, Mitchell DGV, Coleman K, Shoesmith C, Bartha R, Cash DM, Moore KM, van Swieten J, Borroni B, Galimberti D, Tartaglia MC, Rowe J, Graff C, Tagliavini F, Frisoni G, Cappa S, Laforce R Jr, de Mendonça A, Sorbi S, Wallstrom G, Masellis M, Rohrer JD, Finger EC; Genetic FTD Initiative, GENFI.

Neurology. 2019 Oct 29;93(18):e1699-e1706. doi: 10.1212/WNL.0000000000008386. Epub 2019 Oct 2.


Modification of Peak Plasticity Induced by Brief Dark Exposure.

Lingley AJ, Mitchell DE, Crowder NA, Duffy KR.

Neural Plast. 2019 Sep 3;2019:3198285. doi: 10.1155/2019/3198285. eCollection 2019.


Navigating the Wild West of Medication Adherence Reporting in Specialty Pharmacy.

Canfield SL, Zuckerman A, Anguiano RH, Jolly JA, DeClercq J, Wascher M, Choi L, Knox S, Mitchell DG.

J Manag Care Spec Pharm. 2019 Oct;25(10):1073-1077. doi: 10.18553/jmcp.2019.25.10.1073.


Sodium Butylated Hydroxytoluene (NaBHT) as a New and Efficient Hydride Source for Pd-Catalysed Reduction Reactions.

Sharif S, Rodriguez MJ, Lu Y, Kopach ME, Mitchell D, Hunter HN, Organ MG.

Chemistry. 2019 Oct 11;25(57):13099-13103. doi: 10.1002/chem.201902876. Epub 2019 Sep 19.


Probing RNA structure in vivo.

Mitchell D 3rd, Assmann SM, Bevilacqua PC.

Curr Opin Struct Biol. 2019 Dec;59:151-158. doi: 10.1016/ Epub 2019 Sep 13. Review.


The anatomy of a crushing bite: The specialised cranial mechanics of a giant extinct kangaroo.

Mitchell DR.

PLoS One. 2019 Sep 11;14(9):e0221287. doi: 10.1371/journal.pone.0221287. eCollection 2019.


The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection.

Painter GR, Bowen RA, Bluemling GR, DeBergh J, Edpuganti V, Gruddanti PR, Guthrie DB, Hager M, Kuiper DL, Lockwood MA, Mitchell DG, Natchus MG, Sticher ZM, Kolykhalov AA.

Antiviral Res. 2019 Nov;171:104597. doi: 10.1016/j.antiviral.2019.104597. Epub 2019 Sep 5.


CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors.

Jin L, Tao H, Karachi A, Long Y, Hou AY, Na M, Dyson KA, Grippin AJ, Deleyrolle LP, Zhang W, Rajon DA, Wang QJ, Yang JC, Kresak JL, Sayour EJ, Rahman M, Bova FJ, Lin Z, Mitchell DA, Huang J.

Nat Commun. 2019 Sep 5;10(1):4016. doi: 10.1038/s41467-019-11869-4.


Adolescents' perceptions of standardised cigarette packaging design and brand variant name post-implementation: a focus group study in Scotland.

Mitchell D, Moodie C, Critchlow N, Bauld L.

BMC Public Health. 2019 Sep 5;19(1):1227. doi: 10.1186/s12889-019-7552-0.


Common Molecular Alterations in Canine Oligodendroglioma and Human Malignant Gliomas and Potential Novel Therapeutic Targets.

Mitchell D, Chintala S, Fetcko K, Henriquez M, Tewari BN, Ahmed A, Bentley RT, Dey M.

Front Oncol. 2019 Aug 14;9:780. doi: 10.3389/fonc.2019.00780. eCollection 2019.

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