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Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality.

Lagree K, Woolford CA, Huang MY, May G, McManus CJ, Solis NV, Filler SG, Mitchell AP.

PLoS Genet. 2020 Jan 21;16(1):e1008582. doi: 10.1371/journal.pgen.1008582. eCollection 2020 Jan.


Use of High-Cost Cancer Treatments in Academic and Nonacademic Practice.

Mitchell AP, Kinlaw AC, Peacock-Hinton S, Dusetzina SB, Sanoff HK, Lund JL.

Oncologist. 2020 Jan;25(1):46-54. doi: 10.1634/theoncologist.2019-0338. Epub 2019 Oct 14.


Significant Publications on Infectious Diseases Pharmacotherapy in 2018.

Borjan J, Gonzales-Luna AJ, Carlson TJ, Finch NA, Mitchell AP, McDaneld PM, Phe K, Foolad F.

J Pharm Pract. 2019 Oct;32(5):546-557. doi: 10.1177/0897190019863921. Epub 2019 Jul 21. Review.


Genome Sequence for Candida albicans Clinical Oral Isolate 529L.

Cuomo CA, Fanning S, Gujja S, Zeng Q, Naglik JR, Filler SG, Mitchell AP.

Microbiol Resour Announc. 2019 Jun 20;8(25). pii: e00554-19. doi: 10.1128/MRA.00554-19.


Circuit diversification in a biofilm regulatory network.

Huang MY, Woolford CA, May G, McManus CJ, Mitchell AP.

PLoS Pathog. 2019 May 22;15(5):e1007787. doi: 10.1371/journal.ppat.1007787. eCollection 2019 May. Erratum in: PLoS Pathog. 2019 Jul 19;15(7):e1007966.


Candida albicans Morphogenesis Programs Control the Balance between Gut Commensalism and Invasive Infection.

Witchley JN, Penumetcha P, Abon NV, Woolford CA, Mitchell AP, Noble SM.

Cell Host Microbe. 2019 Mar 13;25(3):432-443.e6. doi: 10.1016/j.chom.2019.02.008.


Evaluating the Strength of the Association Between Industry Payments and Prescribing Practices in Oncology.

Mitchell AP, Winn AN, Lund JL, Dusetzina SB.

Oncologist. 2019 May;24(5):632-639. doi: 10.1634/theoncologist.2018-0423. Epub 2019 Feb 6.


Association Between Reimbursement Incentives and Physician Practice in Oncology: A Systematic Review.

Mitchell AP, Rotter JS, Patel E, Richardson D, Wheeler SB, Basch E, Goldstein DA.

JAMA Oncol. 2019 Jun 1;5(6):893-899. doi: 10.1001/jamaoncol.2018.6196.


Function of BriC peptide in the pneumococcal competence and virulence portfolio.

Aggarwal SD, Eutsey R, West-Roberts J, Domenech A, Xu W, Abdullah IT, Mitchell AP, Veening JW, Yesilkaya H, Hiller NL.

PLoS Pathog. 2018 Oct 11;14(10):e1007328. doi: 10.1371/journal.ppat.1007328. eCollection 2018 Oct.


Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity.

Liu H, Xu W, Solis NV, Woolford C, Mitchell AP, Filler SG.

Virulence. 2018;9(1):1062-1073. doi: 10.1080/21505594.2018.1482182.


Impact of surface topography on biofilm formation by Candida albicans.

Lagree K, Mon HH, Mitchell AP, Ducker WA.

PLoS One. 2018 Jun 18;13(6):e0197925. doi: 10.1371/journal.pone.0197925. eCollection 2018.


Risk factors and variations in detection of new bovine tuberculosis breakdowns via slaughterhouse surveillance in Great Britain.

McKinley TJ, Lipschutz-Powell D, Mitchell AP, Wood JLN, Conlan AJK.

PLoS One. 2018 Jun 8;13(6):e0198760. doi: 10.1371/journal.pone.0198760. eCollection 2018.


Rapid Gene Concatenation for Genetic Rescue of Multigene Mutants in Candida albicans.

Huang MY, Woolford CA, Mitchell AP.

mSphere. 2018 Apr 25;3(2). pii: e00169-18. doi: 10.1128/mSphere.00169-18. Print 2018 Apr 25.


Pharmaceutical Industry Payments and Oncologists' Selection of Targeted Cancer Therapies in Medicare Beneficiaries.

Mitchell AP, Winn AN, Dusetzina SB.

JAMA Intern Med. 2018 Jun 1;178(6):854-856. doi: 10.1001/jamainternmed.2018.0776. No abstract available.


Conservation and Divergence in the Candida Species Biofilm Matrix Mannan-Glucan Complex Structure, Function, and Genetic Control.

Dominguez E, Zarnowski R, Sanchez H, Covelli AS, Westler WM, Azadi P, Nett J, Mitchell AP, Andes DR.

mBio. 2018 Apr 3;9(2). pii: e00451-18. doi: 10.1128/mBio.00451-18.


A novel streptococcal cell-cell communication peptide promotes pneumococcal virulence and biofilm formation.

Cuevas RA, Eutsey R, Kadam A, West-Roberts JA, Woolford CA, Mitchell AP, Mason KM, Hiller NL.

Mol Microbiol. 2017 Aug;105(4):554-571. doi: 10.1111/mmi.13721. Epub 2017 Jun 23.


Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage.

Kadam A, Eutsey RA, Rosch J, Miao X, Longwell M, Xu W, Woolford CA, Hillman T, Motib AS, Yesilkaya H, Mitchell AP, Hiller NL.

PLoS Pathog. 2017 May 18;13(5):e1006339. doi: 10.1371/journal.ppat.1006339. eCollection 2017 May.


Negative control of Candida albicans filamentation-associated gene expression by essential protein kinase gene KIN28.

Woolford CA, Lagree K, Aleynikov T, Mitchell AP.

Curr Genet. 2017 Dec;63(6):1073-1079. doi: 10.1007/s00294-017-0705-8. Epub 2017 May 13.


Fungal Biofilms: Inside Out.

Lagree K, Mitchell AP.

Microbiol Spectr. 2017 Apr;5(2). doi: 10.1128/microbiolspec.FUNK-0024-2016. Review.


Location, location, location: Use of CRISPR-Cas9 for genome editing in human pathogenic fungi.

Mitchell AP.

PLoS Pathog. 2017 Mar 30;13(3):e1006209. doi: 10.1371/journal.ppat.1006209. eCollection 2017 Mar. Review. No abstract available.


Marker Recycling in Candida albicans through CRISPR-Cas9-Induced Marker Excision.

Huang MY, Mitchell AP.

mSphere. 2017 Mar 15;2(2). pii: e00050-17. doi: 10.1128/mSphere.00050-17. eCollection 2017 Mar-Apr.


Splenectomy as a Destination: Improving Quality of Care Among Asplenic Veterans Through a Travel Clinic.

Mitchell AP, Boggan JC, Lau K, Simel DL.

Am J Med. 2017 Jul;130(7):856-861. doi: 10.1016/j.amjmed.2017.01.024. Epub 2017 Feb 14.


Genetic evaluation for bovine tuberculosis resistance in dairy cattle.

Banos G, Winters M, Mrode R, Mitchell AP, Bishop SC, Woolliams JA, Coffey MP.

J Dairy Sci. 2017 Feb;100(2):1272-1281. doi: 10.3168/jds.2016-11897. Epub 2016 Dec 9.


Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1.

Woolford CA, Lagree K, Xu W, Aleynikov T, Adhikari H, Sanchez H, Cullen PJ, Lanni F, Andes DR, Mitchell AP.

PLoS Genet. 2016 Dec 9;12(12):e1006487. doi: 10.1371/journal.pgen.1006487. eCollection 2016 Dec.


Financial Relationships With Industry Among National Comprehensive Cancer Network Guideline Authors.

Mitchell AP, Basch EM, Dusetzina SB.

JAMA Oncol. 2016 Dec 1;2(12):1628-1631. doi: 10.1001/jamaoncol.2016.2710.


Candida albicans Gene Deletion with a Transient CRISPR-Cas9 System.

Min K, Ichikawa Y, Woolford CA, Mitchell AP.

mSphere. 2016 Jun 15;1(3). pii: e00130-16. doi: 10.1128/mSphere.00130-16. eCollection 2016 May-Jun.


Sequence-directed nucleosome-depletion is sufficient to activate transcription from a yeast core promoter in vivo.

Ichikawa Y, Morohashi N, Tomita N, Mitchell AP, Kurumizaka H, Shimizu M.

Biochem Biophys Res Commun. 2016 Jul 22;476(2):57-62. doi: 10.1016/j.bbrc.2016.05.063. Epub 2016 May 18.


Microbiology: Fungus produces a toxic surprise.

Mitchell AP.

Nature. 2016 Apr 7;532(7597):41-2. doi: 10.1038/nature17319. Epub 2016 Mar 30. No abstract available.


Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

J Vis Exp. 2016 Jan 13;(107):e53460. doi: 10.3791/53460.


The New Shape of EC.

Mitchell AP.

Eukaryot Cell. 2015 Dec;14(12):1151-2. doi: 10.1128/EC.00139-15.


Pathogen Gene Expression Profiling During Infection Using a Nanostring nCounter Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

Methods Mol Biol. 2016;1361:57-65. doi: 10.1007/978-1-4939-3079-1_3.


Clinical Trial Participants With Metastatic Renal Cell Carcinoma Differ From Patients Treated in Real-World Practice.

Mitchell AP, Harrison MR, Walker MS, George DJ, Abernethy AP, Hirsch BR.

J Oncol Pract. 2015 Nov;11(6):491-7. doi: 10.1200/JOP.2015.004929. Epub 2015 Sep 1.


Coordination of Candida albicans Invasion and Infection Functions by Phosphoglycerol Phosphatase Rhr2.

Desai JV, Cheng S, Ying T, Nguyen MH, Clancy CJ, Lanni F, Mitchell AP.

Pathogens. 2015 Jul 24;4(3):573-89. doi: 10.3390/pathogens4030573.


Candida albicans Biofilm Development and Its Genetic Control.

Desai JV, Mitchell AP.

Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MB-0005-2014.


A Candida albicans Strain Expressing Mammalian Interleukin-17A Results in Early Control of Fungal Growth during Disseminated Infection.

Huppler AR, Whibley N, Woolford CA, Childs EE, He J, Biswas PS, McGeachy MJ, Mitchell AP, Gaffen SL.

Infect Immun. 2015 Sep;83(9):3684-92. doi: 10.1128/IAI.03057-14. Epub 2015 Jul 6.


New signaling pathways govern the host response to C. albicans infection in various niches.

Liu Y, Shetty AC, Schwartz JA, Bradford LL, Xu W, Phan QT, Kumari P, Mahurkar A, Mitchell AP, Ravel J, Fraser CM, Filler SG, Bruno VM.

Genome Res. 2015 May;25(5):679-89. doi: 10.1101/gr.187427.114. Epub 2015 Apr 9.


Deferred systemic therapy in patients with metastatic renal cell carcinoma.

Mitchell AP, Hirsch BR, Harrison MR, Abernethy AP, George DJ.

Clin Genitourin Cancer. 2015 Jun;13(3):e159-66. doi: 10.1016/j.clgc.2014.12.017. Epub 2014 Dec 31.


Community participation in biofilm matrix assembly and function.

Mitchell KF, Zarnowski R, Sanchez H, Edward JA, Reinicke EL, Nett JE, Mitchell AP, Andes DR.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4092-7. doi: 10.1073/pnas.1421437112. Epub 2015 Mar 13.


Potential benefits of cattle vaccination as a supplementary control for bovine tuberculosis.

Conlan AJ, Brooks Pollock E, McKinley TJ, Mitchell AP, Jones GJ, Vordermeier M, Wood JL.

PLoS Comput Biol. 2015 Feb 19;11(2):e1004038. doi: 10.1371/journal.pcbi.1004038. eCollection 2015 Feb.


Activation and alliance of regulatory pathways in C. albicans during mammalian infection.

Xu W, Solis NV, Ehrlich RL, Woolford CA, Filler SG, Mitchell AP.

PLoS Biol. 2015 Feb 18;13(2):e1002076. doi: 10.1371/journal.pbio.1002076. eCollection 2015 Feb.


Divergent targets of Aspergillus fumigatus AcuK and AcuM transcription factors during growth in vitro versus invasive disease.

Pongpom M, Liu H, Xu W, Snarr BD, Sheppard DC, Mitchell AP, Filler SG.

Infect Immun. 2015 Mar;83(3):923-33. doi: 10.1128/IAI.02685-14. Epub 2014 Dec 22.


Sudden motility reversal indicates sensing of magnetic field gradients in Magnetospirillum magneticum AMB-1 strain.

González LM, Ruder WC, Mitchell AP, Messner WC, LeDuc PR.

ISME J. 2015 Jun;9(6):1399-409. doi: 10.1038/ismej.2014.224. Epub 2014 Dec 5.


ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence.

Chung D, Barker BM, Carey CC, Merriman B, Werner ER, Lechner BE, Dhingra S, Cheng C, Xu W, Blosser SJ, Morohashi K, Mazurie A, Mitchell TK, Haas H, Mitchell AP, Cramer RA.

PLoS Pathog. 2014 Nov 6;10(11):e1004487. doi: 10.1371/journal.ppat.1004487. eCollection 2014 Nov. Erratum in: PLoS Pathog. 2014 Nov;10(11):e1004576.


Fungal biofilms, drug resistance, and recurrent infection.

Desai JV, Mitchell AP, Andes DR.

Cold Spring Harb Perspect Med. 2014 Oct 1;4(10). pii: a019729. doi: 10.1101/cshperspect.a019729. Review.


Mutational analysis of essential septins reveals a role for septin-mediated signaling in filamentation.

Blankenship JR, Cheng S, Woolford CA, Xu W, Johnson TM, Rogers PD, Fanning S, Nguyen MH, Clancy CJ, Mitchell AP.

Eukaryot Cell. 2014 Nov;13(11):1403-10. doi: 10.1128/EC.00127-14. Epub 2014 Sep 12.


Rivaroxaban for treatment of venous thromboembolism in older adults.

Mitchell AP, Conway SE.

Consult Pharm. 2014 Sep;29(9):627-30. doi: 10.4140/TCP.n.2014.627. Review.


Disruption of the transcriptional regulator Cas5 results in enhanced killing of Candida albicans by Fluconazole.

Vasicek EM, Berkow EL, Bruno VM, Mitchell AP, Wiederhold NP, Barker KS, Rogers PD.

Antimicrob Agents Chemother. 2014 Nov;58(11):6807-18. doi: 10.1128/AAC.00064-14. Epub 2014 Sep 2.


Novel entries in a fungal biofilm matrix encyclopedia.

Zarnowski R, Westler WM, Lacmbouh GA, Marita JM, Bothe JR, Bernhardt J, Lounes-Hadj Sahraoui A, Fontaine J, Sanchez H, Hatfield RD, Ntambi JM, Nett JE, Mitchell AP, Andes DR.

mBio. 2014 Aug 5;5(4):e01333-14. doi: 10.1128/mBio.01333-14.


Lack of timely accrual information in oncology clinical trials: a cross-sectional analysis.

Mitchell AP, Hirsch BR, Abernethy AP.

Trials. 2014 Mar 25;15:92. doi: 10.1186/1745-6215-15-92.


Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans.

Liu Y, Solis NV, Heilmann CJ, Phan QT, Mitchell AP, Klis FM, Filler SG.

Eukaryot Cell. 2014 Feb;13(2):279-87. doi: 10.1128/EC.00295-13. Epub 2013 Dec 20.

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