Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 25

1.

Chemokine receptor antagonist development.

Garin A, Johnson Z, Hermant A, Beltran F, Ratinaud Y, Michel A, Krohn S, Gaudet M, Carboni S, Ji H, Missotten M, Leger O, Power C, Proudfoot A.

Methods Mol Biol. 2013;1013:67-92. doi: 10.1007/978-1-62703-426-5_6.

PMID:
23625494
2.

Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids.

Crosignani S, Jorand-Lebrun C, Campbell G, Prêtre A, Grippi-Vallotton T, Quattropani A, Bouscary-Desforges G, Bombrun A, Missotten M, Humbert Y, Frémaux C, Pâquet M, El Harkani K, Bradshaw CG, Cleva C, Abla N, Daff H, Schott O, Pittet PA, Arrighi JF, Gaudet M, Johnson Z.

ACS Med Chem Lett. 2011 Oct 10;2(12):938-42. doi: 10.1021/ml200223s. eCollection 2011 Dec 8.

3.

Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.

Crosignani S, Prêtre A, Jorand-Lebrun C, Fraboulet G, Seenisamy J, Augustine JK, Missotten M, Humbert Y, Cleva C, Abla N, Daff H, Schott O, Schneider M, Burgat-Charvillon F, Rivron D, Hamernig I, Arrighi JF, Gaudet M, Zimmerli SC, Juillard P, Johnson Z.

J Med Chem. 2011 Oct 27;54(20):7299-317. doi: 10.1021/jm200866y. Epub 2011 Oct 3.

PMID:
21916510
4.

Optimization of the Central Core of Indolinone-Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists.

Crosignani S, Jorand-Lebrun C, Page P, Campbell G, Colovray V, Missotten M, Humbert Y, Cleva C, Arrighi JF, Gaudet M, Johnson Z, Ferro P, Chollet A.

ACS Med Chem Lett. 2011 Jun 9;2(8):644-9. doi: 10.1021/ml2001196. eCollection 2011 Aug 11.

5.

Discovery of a novel series of CXCR3 antagonists.

Crosignani S, Missotten M, Cleva C, Dondi R, Ratinaud Y, Humbert Y, Mandal AB, Bombrun A, Power C, Chollet A, Proudfoot A.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3614-7. doi: 10.1016/j.bmcl.2010.04.113. Epub 2010 Apr 28.

PMID:
20483605
6.

Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.

Crosignani S, Page P, Missotten M, Colovray V, Cleva C, Arrighi JF, Atherall J, Macritchie J, Martin T, Humbert Y, Gaudet M, Pupowicz D, Maio M, Pittet PA, Golzio L, Giachetti C, Rocha C, Bernardinelli G, Filinchuk Y, Scheer A, Schwarz MK, Chollet A.

J Med Chem. 2008 Apr 10;51(7):2227-43. doi: 10.1021/jm701383e. Epub 2008 Mar 5.

PMID:
18318469
7.

Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP).

Cirillo R, Tos EG, Page P, Missotten M, Quattropani A, Scheer A, Schwarz MK, Chollet A.

Am J Obstet Gynecol. 2007 Jul;197(1):54.e1-9.

PMID:
17618756
8.

G protein-coupled receptor-mediated ERK1/2 phosphorylation: towards a generic sensor of GPCR activation.

Leroy D, Missotten M, Waltzinger C, Martin T, Scheer A.

J Recept Signal Transduct Res. 2007;27(1):83-97.

PMID:
17365511
9.

Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists.

Quattropani A, Dorbais J, Covini D, Pittet PA, Colovray V, Thomas RJ, Coxhead R, Halazy S, Scheer A, Missotten M, Ayala G, Bradshaw C, De Raemy-Schenk AM, Nichols A, Cirillo R, Tos EG, Giachetti C, Golzio L, Marinelli P, Church DJ, Barberis C, Chollet A, Schwarz MK.

J Med Chem. 2005 Dec 1;48(24):7882-905.

PMID:
16302826
10.

The DRY motif as a molecular switch of the human oxytocin receptor.

Favre N, Fanelli F, Missotten M, Nichols A, Wilson J, di Tiani M, Rommel C, Scheer A.

Biochemistry. 2005 Aug 2;44(30):9990-10008.

PMID:
16042376
11.

Pharmacology of (2S,4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a new potent and selective nonpeptide antagonist of the oxytocin receptor.

Cirillo R, Gillio Tos E, Schwarz MK, Quattropani A, Scheer A, Missotten M, Dorbais J, Nichols A, Borrelli F, Giachetti C, Golzio L, Marinelli P, Thomas RJ, Chevillard C, Laurent F, Portet K, Barberis C, Chollet A.

J Pharmacol Exp Ther. 2003 Jul;306(1):253-61. Epub 2003 Mar 26.

PMID:
12660315
13.

Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization.

Chatellard-Causse C, Blot B, Cristina N, Torch S, Missotten M, Sadoul R.

J Biol Chem. 2002 Aug 9;277(32):29108-15. Epub 2002 May 28.

14.

Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein.

Missotten M, Nichols A, Rieger K, Sadoul R.

Cell Death Differ. 1999 Feb;6(2):124-9.

15.

Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons.

Martinou I, Missotten M, Fernandez PA, Sadoul R, Martinou JC.

Neuroreport. 1998 Jan 5;9(1):15-9.

PMID:
9592040
16.

Dissecting processing and apoptotic activity of a cysteine protease by mutant analysis.

Allet B, Hochmann A, Martinou I, Berger A, Missotten M, Antonsson B, Sadoul R, Martinou JC, Bernasconi L.

J Cell Biol. 1996 Oct;135(2):479-86.

17.

Mechanisms of neuronal cell death.

Sadoul R, Dubois-Dauphin M, Fernandez PA, Frankowski H, Quiquerez AL, Martinou I, Missotten M, Pietra C, Martinou JC.

Adv Neurol. 1996;71:419-23; discussion 423-4. No abstract available.

PMID:
8790817
18.

Function and expression of the Bcl-x gene in the developing and adult nervous system.

Frankowski H, Missotten M, Fernandez PA, Martinou I, Michel P, Sadoul R, Martinou JC.

Neuroreport. 1995 Oct 2;6(14):1917-21.

PMID:
8547598
19.

Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation.

Martinou I, Fernandez PA, Missotten M, White E, Allet B, Sadoul R, Martinou JC.

J Cell Biol. 1995 Jan;128(1-2):201-8.

20.

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia.

Martinou JC, Dubois-Dauphin M, Staple JK, Rodriguez I, Frankowski H, Missotten M, Albertini P, Talabot D, Catsicas S, Pietra C, et al.

Neuron. 1994 Oct;13(4):1017-30.

PMID:
7946326
21.

Metabolites of 4-chlorotestosterone acetate in cattle urine as diagnostic markers for its illegal use.

Leyssens L, Royackers E, Gielen B, Missotten M, Schoofs J, Czech J, Noben JP, Hendriks L, Raus J.

J Chromatogr B Biomed Appl. 1994 Mar 18;654(1):43-54.

PMID:
8004242
22.

Bcl-2 and neuronal selection during development of the nervous system.

Martinou JC, Frankowski H, Missotten M, Martinou I, Potier L, Dubois-Dauphin M.

J Physiol Paris. 1994;88(3):209-11. No abstract available.

PMID:
7833862
23.

Molecular characterisation, expression and localisation of human neurokinin-3 receptor.

Buell G, Schulz MF, Arkinstall SJ, Maury K, Missotten M, Adami N, Talabot F, Kawashima E.

FEBS Lett. 1992 Mar 24;299(1):90-5.

24.
25.

Functional characterization of a cAMP-responsive element of the rat insulin I gene.

Philippe J, Missotten M.

J Biol Chem. 1990 Jan 25;265(3):1465-9.

Supplemental Content

Loading ...
Support Center