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Items: 1 to 50 of 204

1.

Improving North Atlantic Marine Core Chronologies Using 230Th Normalization.

Missiaen L, Waelbroeck C, Pichat S, Jaccard SL, Eynaud F, Greenop R, Burke A.

Paleoceanogr Paleoclimatol. 2019 Jul;34(7):1057-1073. doi: 10.1029/2018PA003444. Epub 2019 Jul 10.

2.

Consistently dated Atlantic sediment cores over the last 40 thousand years.

Waelbroeck C, Lougheed BC, Vazquez Riveiros N, Missiaen L, Pedro J, Dokken T, Hajdas I, Wacker L, Abbott P, Dumoulin JP, Thil F, Eynaud F, Rossignol L, Fersi W, Albuquerque AL, Arz H, Austin WEN, Came R, Carlson AE, Collins JA, Dennielou B, Desprat S, Dickson A, Elliot M, Farmer C, Giraudeau J, Gottschalk J, Henderiks J, Hughen K, Jung S, Knutz P, Lebreiro S, Lund DC, Lynch-Stieglitz J, Malaizé B, Marchitto T, Martínez-Méndez G, Mollenhauer G, Naughton F, Nave S, Nürnberg D, Oppo D, Peck V, Peeters FJC, Penaud A, Portilho-Ramos RDC, Repschläger J, Roberts J, Rühlemann C, Salgueiro E, Sanchez Goni MF, Schönfeld J, Scussolini P, Skinner LC, Skonieczny C, Thornalley D, Toucanne S, Rooij DV, Vidal L, Voelker AHL, Wary M, Weldeab S, Ziegler M.

Sci Data. 2019 Sep 2;6(1):165. doi: 10.1038/s41597-019-0173-8.

3.

A critical appraisal of the role of intracellular Ca2+-signaling pathways in Kawasaki disease.

Bijnens J, Missiaen L, Bultynck G, Parys JB.

Cell Calcium. 2018 May;71:95-103. doi: 10.1016/j.ceca.2018.01.002. Epub 2018 Feb 3. Review.

PMID:
29604968
4.

Ca(2+) signalling in human proximal tubular epithelial cells deficient for cystinosin.

Ivanova EA, Elmonem MA, Bongaerts I, Luyten T, Missiaen L, van den Heuvel LP, Levtchenko EN, Bultynck G.

Cell Calcium. 2016 Oct;60(4):282-7. doi: 10.1016/j.ceca.2016.07.001. Epub 2016 Jul 5.

PMID:
27451386
5.

Altered mTOR signalling in nephropathic cystinosis.

Ivanova EA, van den Heuvel LP, Elmonem MA, De Smedt H, Missiaen L, Pastore A, Mekahli D, Bultynck G, Levtchenko EN.

J Inherit Metab Dis. 2016 May;39(3):457-464. doi: 10.1007/s10545-016-9919-z. Epub 2016 Feb 24.

PMID:
26909499
6.

Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domain.

Vervliet T, Lemmens I, Vandermarliere E, Decrock E, Ivanova H, Monaco G, Sorrentino V, Nadif Kasri N, Missiaen L, Martens L, De Smedt H, Leybaert L, Parys JB, Tavernier J, Bultynck G.

Sci Rep. 2015 Apr 15;5:9641. doi: 10.1038/srep09641.

7.

Bcl-2 binds to and inhibits ryanodine receptors.

Vervliet T, Decrock E, Molgó J, Sorrentino V, Missiaen L, Leybaert L, De Smedt H, Kasri NN, Parys JB, Bultynck G.

J Cell Sci. 2014 Jun 15;127(Pt 12):2782-92. doi: 10.1242/jcs.150011. Epub 2014 Apr 24.

8.

Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival.

Ivanova H, Vervliet T, Missiaen L, Parys JB, De Smedt H, Bultynck G.

Biochim Biophys Acta. 2014 Oct;1843(10):2164-83. doi: 10.1016/j.bbamcr.2014.03.007. Epub 2014 Mar 15. Review.

9.

Measurement of intracellular Ca2+ release in intact cells using 45Ca2+.

Luyten T, Bultynck G, Parys JB, De Smedt H, Missiaen L.

Cold Spring Harb Protoc. 2014 Mar 1;2014(3):284-8. doi: 10.1101/pdb.prot073197.

PMID:
24591687
10.

Measurement of intracellular Ca2+ release in permeabilized cells using 45Ca2+.

Luyten T, Bultynck G, Parys JB, De Smedt H, Missiaen L.

Cold Spring Harb Protoc. 2014 Mar 1;2014(3):289-94. doi: 10.1101/pdb.prot073189.

PMID:
24591686
11.

Measurement of intracellular Ca2+ release in intact and permeabilized cells using 45Ca2+.

Missiaen L, Luyten T, Bultynck G, Parys JB, De Smedt H.

Cold Spring Harb Protoc. 2014 Mar 1;2014(3):263-70. doi: 10.1101/pdb.top066126.

PMID:
24591684
12.

Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.

Mekahli D, Decuypere JP, Sammels E, Welkenhuyzen K, Schoeber J, Audrezet MP, Corvelyn A, Dechênes G, Ong AC, Wilmer MJ, van den Heuvel L, Bultynck G, Parys JB, Missiaen L, Levtchenko E, De Smedt H.

Pflugers Arch. 2014 Aug;466(8):1591-604. doi: 10.1007/s00424-013-1394-x. Epub 2013 Nov 6.

PMID:
24193408
13.

Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor.

Monaco G, Decrock E, Nuyts K, Wagner LE 2nd, Luyten T, Strelkov SV, Missiaen L, De Borggraeve WM, Leybaert L, Yule DI, De Smedt H, Parys JB, Bultynck G.

PLoS One. 2013 Aug 30;8(8):e73386. doi: 10.1371/journal.pone.0073386. eCollection 2013.

14.

IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.

Akl H, Monaco G, La Rovere R, Welkenhuyzen K, Kiviluoto S, Vervliet T, Molgó J, Distelhorst CW, Missiaen L, Mikoshiba K, Parys JB, De Smedt H, Bultynck G.

Cell Death Dis. 2013 May 16;4:e632. doi: 10.1038/cddis.2013.140.

15.

mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.

Decuypere JP, Kindt D, Luyten T, Welkenhuyzen K, Missiaen L, De Smedt H, Bultynck G, Parys JB.

PLoS One. 2013;8(4):e61020. doi: 10.1371/journal.pone.0061020. Epub 2013 Apr 2.

16.

Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress.

Kiviluoto S, Vervliet T, Ivanova H, Decuypere JP, De Smedt H, Missiaen L, Bultynck G, Parys JB.

Biochim Biophys Acta. 2013 Jul;1833(7):1612-24. doi: 10.1016/j.bbamcr.2013.01.026. Epub 2013 Feb 1. Review.

17.

Polycystins and cellular Ca2+ signaling.

Mekahli D, Parys JB, Bultynck G, Missiaen L, De Smedt H.

Cell Mol Life Sci. 2013 Aug;70(15):2697-712. doi: 10.1007/s00018-012-1188-x. Epub 2012 Oct 18. Review.

18.

Profiling of the Bcl-2/Bcl-X(L)-binding sites on type 1 IP(3) receptor.

Monaco G, Beckers M, Ivanova H, Missiaen L, Parys JB, De Smedt H, Bultynck G.

Biochem Biophys Res Commun. 2012 Nov 9;428(1):31-5. doi: 10.1016/j.bbrc.2012.10.002. Epub 2012 Oct 8.

PMID:
23058917
19.

Bax inhibitor-1 is a novel IP₃ receptor-interacting and -sensitizing protein.

Kiviluoto S, Schneider L, Luyten T, Vervliet T, Missiaen L, De Smedt H, Parys JB, Methner A, Bultynck G.

Cell Death Dis. 2012 Aug 9;3:e367. doi: 10.1038/cddis.2012.103. No abstract available.

20.

Polycystin-1 and polycystin-2 are both required to amplify inositol-trisphosphate-induced Ca2+ release.

Mekahli D, Sammels E, Luyten T, Welkenhuyzen K, van den Heuvel LP, Levtchenko EN, Gijsbers R, Bultynck G, Parys JB, De Smedt H, Missiaen L.

Cell Calcium. 2012 Jun;51(6):452-8. doi: 10.1016/j.ceca.2012.03.002. Epub 2012 Mar 27.

PMID:
22456092
21.

The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.

Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A.

J Biol Chem. 2012 Jan 20;287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28.

22.

Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.

Decuypere JP, Welkenhuyzen K, Luyten T, Ponsaerts R, Dewaele M, Molgó J, Agostinis P, Missiaen L, De Smedt H, Parys JB, Bultynck G.

Autophagy. 2011 Dec;7(12):1472-89.

23.

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

Monaco G, Decrock E, Akl H, Ponsaerts R, Vervliet T, Luyten T, De Maeyer M, Missiaen L, Distelhorst CW, De Smedt H, Parys JB, Leybaert L, Bultynck G.

Cell Death Differ. 2012 Feb;19(2):295-309. doi: 10.1038/cdd.2011.97. Epub 2011 Aug 5.

24.

STIM1 as a key regulator for Ca2+ homeostasis in skeletal-muscle development and function.

Kiviluoto S, Decuypere JP, De Smedt H, Missiaen L, Parys JB, Bultynck G.

Skelet Muscle. 2011 Apr 4;1(1):16. doi: 10.1186/2044-5040-1-16.

25.

Systematic review: the pathophysiology and management of polycystic liver disease.

Temmerman F, Missiaen L, Bammens B, Laleman W, Cassiman D, Verslype C, van Pelt J, Nevens F.

Aliment Pharmacol Ther. 2011 Oct;34(7):702-13. doi: 10.1111/j.1365-2036.2011.04783.x. Epub 2011 Jul 26. Review.

26.

Endoplasmic-reticulum calcium depletion and disease.

Mekahli D, Bultynck G, Parys JB, De Smedt H, Missiaen L.

Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6). pii: a004317. doi: 10.1101/cshperspect.a004317. Review.

27.

IP(3) Receptors, Mitochondria, and Ca Signaling: Implications for Aging.

Decuypere JP, Monaco G, Missiaen L, De Smedt H, Parys JB, Bultynck G.

J Aging Res. 2011 Mar 8;2011:920178. doi: 10.4061/2011/920178.

28.

Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca signaling.

Sammels E, Devogelaere B, Mekahli D, Bultynck G, Missiaen L, Parys JB, De Smedt H.

Commun Integr Biol. 2010 Nov;3(6):530-2. doi: 10.4161/cib.3.6.12751. Epub 2010 Nov 1.

29.

The IP(3) receptor-mitochondria connection in apoptosis and autophagy.

Decuypere JP, Monaco G, Bultynck G, Missiaen L, De Smedt H, Parys JB.

Biochim Biophys Acta. 2011 May;1813(5):1003-13. doi: 10.1016/j.bbamcr.2010.11.023. Epub 2010 Dec 10. Review.

30.

STIM1, but not STIM2, is required for proper agonist-induced Ca2+ signaling.

Decuypere JP, Monaco G, Kiviluoto S, Oh-hora M, Luyten T, De Smedt H, Parys JB, Missiaen L, Bultynck G.

Cell Calcium. 2010 Aug-Sep;48(2-3):161-7. doi: 10.1016/j.ceca.2010.08.003.

PMID:
20801505
31.

Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.

Sammels E, Devogelaere B, Mekahli D, Bultynck G, Missiaen L, Parys JB, Cai Y, Somlo S, De Smedt H.

J Biol Chem. 2010 Jun 11;285(24):18794-805. doi: 10.1074/jbc.M109.090662. Epub 2010 Apr 7.

32.

Intracellular Ca2+ storage in health and disease: a dynamic equilibrium.

Sammels E, Parys JB, Missiaen L, De Smedt H, Bultynck G.

Cell Calcium. 2010 Apr;47(4):297-314. doi: 10.1016/j.ceca.2010.02.001. Epub 2010 Mar 1. Review.

PMID:
20189643
33.

Intracellular Ca2+- and Mn2+-transport ATPases.

Vangheluwe P, Sepúlveda MR, Missiaen L, Raeymaekers L, Wuytack F, Vanoevelen J.

Chem Rev. 2009 Oct;109(10):4733-59. doi: 10.1021/cr900013m. Review. No abstract available.

PMID:
19678701
34.

Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation.

Vanderheyden V, Devogelaere B, Missiaen L, De Smedt H, Bultynck G, Parys JB.

Biochim Biophys Acta. 2009 Jun;1793(6):959-70. doi: 10.1016/j.bbamcr.2008.12.003. Epub 2008 Dec 16. Review.

35.

Contribution of intracellular Ca2+ stores to Ca2+ signaling during chemokinesis of human neutrophil granulocytes.

Baron S, Struyf S, Wuytack F, Van Damme J, Missiaen L, Raeymaekers L, Vanoevelen J.

Biochim Biophys Acta. 2009 Jun;1793(6):1041-9. doi: 10.1016/j.bbamcr.2008.11.005. Epub 2008 Nov 27.

36.

Diseases involving the Golgi calcium pump.

Vanoevelen J, Dode L, Raeymaekers L, Wuytack F, Missiaen L.

Subcell Biochem. 2007;45:385-404. Review.

PMID:
18193645
37.

Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca2+ leak and disturbs Ca2+ signalling.

Verbert L, Lee B, Kocks SL, Assefa Z, Parys JB, Missiaen L, Callewaert G, Fissore RA, De Smedt H, Bultynck G.

Biol Cell. 2008 Jan;100(1):39-49.

38.

Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor.

Devogelaere B, Beullens M, Sammels E, Derua R, Waelkens E, van Lint J, Parys JB, Missiaen L, Bollen M, De Smedt H.

Biochem J. 2007 Oct 15;407(2):303-11.

39.

The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor.

Devogelaere B, Verbert L, Parys JB, Missiaen L, De Smedt H.

Cell Calcium. 2008 Jan;43(1):17-27. Epub 2007 May 17. Review.

PMID:
17499849
40.

Biphenyl 2,3',4,5',6-pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca2+ responses in rat hepatocytes.

Vandeput F, Combettes L, Mills SJ, Backers K, Wohlkönig A, Parys JB, De Smedt H, Missiaen L, Dupont G, Potter BV, Erneux C.

FASEB J. 2007 May;21(7):1481-91. Epub 2007 Jan 30.

PMID:
17264160
41.

Calcium in the Golgi apparatus.

Missiaen L, Dode L, Vanoevelen J, Raeymaekers L, Wuytack F.

Cell Calcium. 2007 May;41(5):405-16. Epub 2006 Nov 30. Review.

PMID:
17140658
42.

Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knock-out cells.

Kasri NN, Kocks SL, Verbert L, Hébert SS, Callewaert G, Parys JB, Missiaen L, De Smedt H.

Cell Calcium. 2006 Jul;40(1):41-51. Epub 2006 May 3.

PMID:
16675011
43.

Binding of IRBIT to the IP3 receptor: determinants and functional effects.

Devogelaere B, Nadif Kasri N, Derua R, Waelkens E, Callewaert G, Missiaen L, Parys JB, De Smedt H.

Biochem Biophys Res Commun. 2006 Apr 28;343(1):49-56. Epub 2006 Feb 28.

PMID:
16527252
44.

The suppressor domain of inositol 1,4,5-trisphosphate receptor plays an essential role in the protection against apoptosis.

Szlufcik K, Bultynck G, Callewaert G, Missiaen L, Parys JB, De Smedt H.

Cell Calcium. 2006 Apr;39(4):325-36. Epub 2006 Feb 3.

PMID:
16458354
45.

Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy.

Buytaert E, Callewaert G, Hendrickx N, Scorrano L, Hartmann D, Missiaen L, Vandenheede JR, Heirman I, Grooten J, Agostinis P.

FASEB J. 2006 Apr;20(6):756-8. Epub 2006 Feb 2.

PMID:
16455754
46.

Endogenously bound calmodulin is essential for the function of the inositol 1,4,5-trisphosphate receptor.

Kasri NN, Török K, Galione A, Garnham C, Callewaert G, Missiaen L, Parys JB, De Smedt H.

J Biol Chem. 2006 Mar 31;281(13):8332-8. Epub 2006 Jan 12.

47.

Uncoupled IP3 receptor can function as a Ca2+-leak channel: cell biological and pathological consequences.

Szlufcik K, Missiaen L, Parys JB, Callewaert G, De Smedt H.

Biol Cell. 2006 Jan;98(1):1-14. Review.

PMID:
16354157
48.

Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.

Dode L, Andersen JP, Vanoevelen J, Raeymaekers L, Missiaen L, Vilsen B, Wuytack F.

J Biol Chem. 2006 Feb 10;281(6):3182-9. Epub 2005 Dec 6.

49.

Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses.

Dode L, Andersen JP, Raeymaekers L, Missiaen L, Vilsen B, Wuytack F.

J Biol Chem. 2005 Nov 25;280(47):39124-34. Epub 2005 Sep 28.

50.

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